Institut for Biomedicin

Asbjørn Mohr Drewes

Hyper-IgE-syndromet. Job's syndrom

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Since 1972, 150 cases of the hyper-IgE-syndrome have been reported. The clinical manifestations are rather homogeneous with recurrent subcutaneous infections and infections in the respiratory tract, mostly with juvenile onset. Laboratory tests show minor eosinophilia and elevated immunoglobulin E-levels are always seen, partly specific to Staphylococcus aureus. Also varying decreases of polymorphonuclear leucocyte-chemotactic response are seen. There is no specific treatment of the disorder, only treatment of current infections has proved valuable. A case history is presented.
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind152
Nummer34
Sider (fra-til)2417-20
Antal sider4
ISSN0041-5782
StatusUdgivet - 1990

    Forskningsområder

  • Humans, Immunoglobulin E, Job's Syndrome, Male, Middle Aged, Phagocyte Bactericidal Dysfunction

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