Mechanisms of antidepressant action: an integrated dopaminergic perspective

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Standard

Mechanisms of antidepressant action : an integrated dopaminergic perspective. / Porcelli, S; Drago, A; Fabbri, C; Serretti, A.

I: Progress in Neuro-Psychopharmacology & Biological Psychiatry, Bind 35, Nr. 7, 15.08.2011, s. 1532-43.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Porcelli, S, Drago, A, Fabbri, C & Serretti, A 2011, 'Mechanisms of antidepressant action: an integrated dopaminergic perspective', Progress in Neuro-Psychopharmacology & Biological Psychiatry, bind 35, nr. 7, s. 1532-43. https://doi.org/10.1016/j.pnpbp.2011.03.005

APA

Porcelli, S., Drago, A., Fabbri, C., & Serretti, A. (2011). Mechanisms of antidepressant action: an integrated dopaminergic perspective. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 35(7), 1532-43. https://doi.org/10.1016/j.pnpbp.2011.03.005

CBE

Porcelli S, Drago A, Fabbri C, Serretti A. 2011. Mechanisms of antidepressant action: an integrated dopaminergic perspective. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35(7):1532-43. https://doi.org/10.1016/j.pnpbp.2011.03.005

MLA

Porcelli, S o.a.. "Mechanisms of antidepressant action: an integrated dopaminergic perspective". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2011, 35(7). 1532-43. https://doi.org/10.1016/j.pnpbp.2011.03.005

Vancouver

Porcelli S, Drago A, Fabbri C, Serretti A. Mechanisms of antidepressant action: an integrated dopaminergic perspective. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2011 aug. 15;35(7):1532-43. https://doi.org/10.1016/j.pnpbp.2011.03.005

Author

Porcelli, S ; Drago, A ; Fabbri, C ; Serretti, A. / Mechanisms of antidepressant action : an integrated dopaminergic perspective. I: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2011 ; Bind 35, Nr. 7. s. 1532-43.

Bibtex

@article{9cbebf7546c24596b03b0bbc55a5c5e6,
title = "Mechanisms of antidepressant action: an integrated dopaminergic perspective",
abstract = "The molecular mechanisms that cause and maintain the major depressive disorder (MDD) are currently unknown. Consistently, antidepressant treatments are characterized by insufficient success rates. This causes high social costs and severe personal sufferings. In the present review we analyze some of the paradigms that are used to explain MDD, particularly from the perspective of the dopaminergic (DA) system. DA has been more classically associated with psychosis and substance abuse disorders, even though a role of DA in MDD has been proposed as well and some antidepressants with DA profile exist. In the present work, we review some of the molecular mechanisms that underpin MDD from the perspective of the dopaminergic system, in the hope of unifying some of the major theories of MDD - the monoaminergic, inflammatory, epigenetics, neurotrophin and anti-apoptotic theories. Several shared components of these theories are highlighted, partially accounted by the functions of the DA system (see supplementary video).",
keywords = "Antidepressive Agents, Biogenic Monoamines, Depressive Disorder, Major, Dopamine, Dopamine Agents, Humans, Inflammation, Nerve Growth Factors",
author = "S Porcelli and A Drago and C Fabbri and A Serretti",
note = "Copyright {\textcopyright} 2011 Elsevier Inc. All rights reserved.",
year = "2011",
month = aug,
day = "15",
doi = "10.1016/j.pnpbp.2011.03.005",
language = "English",
volume = "35",
pages = "1532--43",
journal = "Progress in Neuro-Psychopharmacology & Biological Psychiatry",
issn = "0278-5846",
publisher = "Elsevier Inc.",
number = "7",

}

RIS

TY - JOUR

T1 - Mechanisms of antidepressant action

T2 - an integrated dopaminergic perspective

AU - Porcelli, S

AU - Drago, A

AU - Fabbri, C

AU - Serretti, A

N1 - Copyright © 2011 Elsevier Inc. All rights reserved.

PY - 2011/8/15

Y1 - 2011/8/15

N2 - The molecular mechanisms that cause and maintain the major depressive disorder (MDD) are currently unknown. Consistently, antidepressant treatments are characterized by insufficient success rates. This causes high social costs and severe personal sufferings. In the present review we analyze some of the paradigms that are used to explain MDD, particularly from the perspective of the dopaminergic (DA) system. DA has been more classically associated with psychosis and substance abuse disorders, even though a role of DA in MDD has been proposed as well and some antidepressants with DA profile exist. In the present work, we review some of the molecular mechanisms that underpin MDD from the perspective of the dopaminergic system, in the hope of unifying some of the major theories of MDD - the monoaminergic, inflammatory, epigenetics, neurotrophin and anti-apoptotic theories. Several shared components of these theories are highlighted, partially accounted by the functions of the DA system (see supplementary video).

AB - The molecular mechanisms that cause and maintain the major depressive disorder (MDD) are currently unknown. Consistently, antidepressant treatments are characterized by insufficient success rates. This causes high social costs and severe personal sufferings. In the present review we analyze some of the paradigms that are used to explain MDD, particularly from the perspective of the dopaminergic (DA) system. DA has been more classically associated with psychosis and substance abuse disorders, even though a role of DA in MDD has been proposed as well and some antidepressants with DA profile exist. In the present work, we review some of the molecular mechanisms that underpin MDD from the perspective of the dopaminergic system, in the hope of unifying some of the major theories of MDD - the monoaminergic, inflammatory, epigenetics, neurotrophin and anti-apoptotic theories. Several shared components of these theories are highlighted, partially accounted by the functions of the DA system (see supplementary video).

KW - Antidepressive Agents

KW - Biogenic Monoamines

KW - Depressive Disorder, Major

KW - Dopamine

KW - Dopamine Agents

KW - Humans

KW - Inflammation

KW - Nerve Growth Factors

U2 - 10.1016/j.pnpbp.2011.03.005

DO - 10.1016/j.pnpbp.2011.03.005

M3 - Journal article

C2 - 21402119

VL - 35

SP - 1532

EP - 1543

JO - Progress in Neuro-Psychopharmacology & Biological Psychiatry

JF - Progress in Neuro-Psychopharmacology & Biological Psychiatry

SN - 0278-5846

IS - 7

ER -