Incomplete coverage of candidate genes: a poorly considered bias

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Standard

Incomplete coverage of candidate genes : a poorly considered bias. / Drago, Antonio; De Ronchi, Diana; Serretti, Alessandro.

I: Current genomics, Bind 8, Nr. 7, 11.2007, s. 476-83.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Drago, A, De Ronchi, D & Serretti, A 2007, 'Incomplete coverage of candidate genes: a poorly considered bias', Current genomics, bind 8, nr. 7, s. 476-83. https://doi.org/10.2174/138920207783591681

APA

Drago, A., De Ronchi, D., & Serretti, A. (2007). Incomplete coverage of candidate genes: a poorly considered bias. Current genomics, 8(7), 476-83. https://doi.org/10.2174/138920207783591681

CBE

Drago A, De Ronchi D, Serretti A. 2007. Incomplete coverage of candidate genes: a poorly considered bias. Current genomics. 8(7):476-83. https://doi.org/10.2174/138920207783591681

MLA

Drago, Antonio, Diana De Ronchi og Alessandro Serretti. "Incomplete coverage of candidate genes: a poorly considered bias". Current genomics. 2007, 8(7). 476-83. https://doi.org/10.2174/138920207783591681

Vancouver

Drago A, De Ronchi D, Serretti A. Incomplete coverage of candidate genes: a poorly considered bias. Current genomics. 2007 nov.;8(7):476-83. https://doi.org/10.2174/138920207783591681

Author

Drago, Antonio ; De Ronchi, Diana ; Serretti, Alessandro. / Incomplete coverage of candidate genes : a poorly considered bias. I: Current genomics. 2007 ; Bind 8, Nr. 7. s. 476-83.

Bibtex

@article{dc0bb6ce9c724dc4bccf8b01d28d6aab,
title = "Incomplete coverage of candidate genes: a poorly considered bias",
abstract = "Current genetic investigations are performed both on the basis of a rational and biologically based choice of candidate genes and through genome wide scans. Nonetheless, lack of replication is a common problem in psychiatric genetics as well as in other genetic fields. There are a number of reasons for this inconsistency, among them a well known but poorly considered issue is gene coverage. The aim of the present paper is to focus on this well known and defectively deemed bias, especially when a candidate gene approach is chosen. The rational and the technical feasibility of this proposal are discussed as well as a survey of current investigations. The known consistent methodology to fix this bias is also discussed.",
author = "Antonio Drago and {De Ronchi}, Diana and Alessandro Serretti",
year = "2007",
month = nov,
doi = "10.2174/138920207783591681",
language = "English",
volume = "8",
pages = "476--83",
journal = "Current genomics",
issn = "1389-2029",
publisher = "Bentham Science Publishers B.V.",
number = "7",

}

RIS

TY - JOUR

T1 - Incomplete coverage of candidate genes

T2 - a poorly considered bias

AU - Drago, Antonio

AU - De Ronchi, Diana

AU - Serretti, Alessandro

PY - 2007/11

Y1 - 2007/11

N2 - Current genetic investigations are performed both on the basis of a rational and biologically based choice of candidate genes and through genome wide scans. Nonetheless, lack of replication is a common problem in psychiatric genetics as well as in other genetic fields. There are a number of reasons for this inconsistency, among them a well known but poorly considered issue is gene coverage. The aim of the present paper is to focus on this well known and defectively deemed bias, especially when a candidate gene approach is chosen. The rational and the technical feasibility of this proposal are discussed as well as a survey of current investigations. The known consistent methodology to fix this bias is also discussed.

AB - Current genetic investigations are performed both on the basis of a rational and biologically based choice of candidate genes and through genome wide scans. Nonetheless, lack of replication is a common problem in psychiatric genetics as well as in other genetic fields. There are a number of reasons for this inconsistency, among them a well known but poorly considered issue is gene coverage. The aim of the present paper is to focus on this well known and defectively deemed bias, especially when a candidate gene approach is chosen. The rational and the technical feasibility of this proposal are discussed as well as a survey of current investigations. The known consistent methodology to fix this bias is also discussed.

U2 - 10.2174/138920207783591681

DO - 10.2174/138920207783591681

M3 - Journal article

C2 - 19412419

VL - 8

SP - 476

EP - 483

JO - Current genomics

JF - Current genomics

SN - 1389-2029

IS - 7

ER -