Aarhus Universitets segl

Anna Schönherz


Profile photoAnna A. Schönherz
Institut for Husdyr- og Veterinærvidenskab - Sundhed for tarm og vært (GHH)
iCLIMATE Aarhus University Interdisciplinary Centre for Climate Change
Blichers Allé 20
D23, 3213
E-mail: anna.schonherz@anivet.au.dk

Research Focus

My research aims at gaining a better understanding of gastrointestinal microbiota dynamics, activity and host-microbiome interactions (e.g., microbiota-gut brain axis signaling) in monogastric and ruminant livestock species with the emphasis to explore strategies of microbial alteration for disease prevention, reduced antibiotic usage and methane mitigation. In this work, I exploit high-throughput ‘omics’ data and utilizes comparative as well as integrative computational approaches

Area of Expertise

- Bioinformatics of high-throughput ‘omics’ data
- Linux-based high-performance computing
- Gut metagenomics
- Host-microbiome interaction
- Population genomics
- Phylogenetic and evolutionary analysis
- Viral evolution and genomics
- Pathway and network analyses


June 2014: PhD in Genetics, Dept. of Molecular Biology and Genetics, Aahus University of Molecular Biology and Genetics, Aarhus University (AU)
August 2011: MSc in Agrobiology, Dept. of Molecular Biology and Genetics


Research Scientist in Bioinformatics and Metagenomics, Dept. of Animal Science, AU
Postdoc in Population Genomics, Center for Quantitative Genetics and Genomics, AU
Postdoc in Clinical Bioinformatics, Dept. of Clinical Medicine, Aalborg University
Postdoc in Genomics, Dept. of Molecular Biology and Genetics, AU


Reduceret metanproduktion med optimeret mælkeproduktion: Udnyttelse af samspillet mellem foderadditiver, den enkelte kos genetik og vommens mikrober (INCOME). Role: WP Leader

PIG-PARADIGM: Preventing Infection in the Gut of developing Piglets -and thus Antimicrobial Resistance - by disentAngling the interface of DIet, the host and the Gastrointestinal Microbiome. Role: WP Co-Leader

MethEnzwine Reducing methane emissions and improving growth performance and health with a novel enzyme applied to swine. Role: Participant

NO-METHANE: Novel triple action feed additive approach to reduce enteric methane emission from cattle by blocking the enzymatic process, draining the hydrogen substrate and suppressing methanogenic archaea (NO-METHANE). Role: Participant

UVIBA: UV kombilys i staldmiljø - virkning og effekt (UVIBA). Role: Participant

FF-KO: Feeding and phenotype of the climate-efficient dairy cow. Role: Participant

FORFRA: Feed the pigs and train the enzymes prior to weaning. Role: Participant

Dansk Korthornsavl i Fremtiden - Genomisk Kortlægning af Korthornspopulationer; Role: Grant holder

Genomic Characterization of Native Norwegian Cattle breeds. Role: WP Co-Leader

Biodiversity within and between European Red dairy breeds - conservation through utilization (REDIVERSE). Role: Participant

National Experimental Therapy Partnership (NEXT) – Bioinformatics. Role: Participant

Genetisk struktur, genomisk indavl og forbedret avlsplanlægning i bevaringsracer af danske husdyr. Role: Participant

Leadership and Administration

2019-2022: Project leader of one and WP leader of 3 projects
2016-2022: Co-supervisor of 2 BSc, 4 MSc and 2 PhD students
2019: Organization and session chair of the 5th Annual Danish Bioinformatic Conference
2018: Organization of the 4th Annual Danish Bioinformatic Conference
2013: Organization of the Annual PhD workshop, Dept. of Molecular Biology and
Genetics, AU

Academic Awards and Honours

2012: Best research presentation, PhD-Day, Dept. of Molecular Biology and Genetics, AU, DK
2010: Best newcomer poster, Shell Fish Immunology Workshop, Wageningen University, Netherlands


2022: Instructor at the international PhD course 'Gut Biology and Health, AU (5 ECTS)
2020-2022: Instructor at the BSc course “AgroMicrobiology”, AU (10 ECTS
2020:Instructor at the BSc course “Angewandte Tierzucht”, Rheinische Friedrich-Wilhelms-Universität Bonn (10 ECTS)
2018-2020: Instructor at the MSc course “Conservation Genetics and Molecular Ecology”, AU (10 ECTS)
2017: Course coordinator and instructor for the PhD course “How to analyze and interpret large datasets from emerging – omics based technologies in clinical settings”,
Aalborg University (5 ECTS)

2014-2015:Instructor at the BSc course “Genetics & Evolutionary Genetics”, AU (10 ECTS)
2013: Instructor at the EURL Training Course “Molecular techniques and bioinformatics”, National Veterinary Institute, Technical University of Denmark
2010- 2013: Student assistant at the BSc course “Genetics & Evolutionary Genetics”, AU
2011-2012: Instructor at the High school outreaching program, AU

Scientific qualifications

Project Management for Researchers, Aalborg University
High-Throughput Biology: From Sequence to Networks, Cold Spring Harbor Laboratory
Conferences: 15 poster presentations, 7 oral presentations
Publications: 23 peer-reviewed articles, 6conference proceedings, 2 non peer-reviewed publications, Google Scholar: 198, h-index: 8;Scopus: 143, h-index: 8 (05-10-2022)


Enteric methane emission of dairy cows supplemented with iodoform in a dose–response study

Thorsteinsson, M., Lund, P., Weisbjerg, M. R., Noel, S. J., Schönherz, A. A., Hellwing, A. L. F., Hansen, H. H. & Nielsen, M. O., aug. 2023, I: Scientific Reports. 13, 1, 20 s., 12797.

A westernized diet changed the colonic bacterial composition and metabolite concentration in a dextran sulfate sodium pig model for ulcerative colitis

M. Panah, F., Nielsen, K. D., Simpson, G., Schönherz, A. A., Schramm, A., Lauridsen, C., Nielsen, T. S., Højberg, O., Fredborg, M., Purup, S. & Canibe, N., apr. 2023, I: Frontiers in Microbiology. 14, 17 s., 1018242.

Corrigendum: A westernized diet changed the colonic bacterial composition and metabolite concentration in a dextran sulfate sodium pig model for ulcerative colitis

Panah, F. M., Nielsen, K. D., Simpson, G. L., Schönherz, A., Schramm, A., Lauridsen, C., Nielsen, T. S., Højberg, O., Fredborg, M., Purup, S. & Canibe, N., 2023, I: Frontiers in Microbiology. 14, 1238157.

Inbreeding and pedigree analysis of the European red dairy cattle

Nyman, S., Johansson, A. M., Palucci, V., Schönherz, A. A., Guldbrandtsen, B., Hinrichs, D. & de Koning, D. J., okt. 2022, I: Genetics Selection Evolution. 54, 70.

Weaning intact litters in farrowing pens for loose housed sows: diarrhoea and microbiota composition

Winters, J. F. M., Schönherz, A. A., Canibe, N., Foldager, L. & Pedersen, L. J., sep. 2022, Book of Abstracts of the 73rd Annual Meeting of the European Federation of Animal Science. Wageningen Academic Publishers, s. 348-348 (EAAP Book of Abstracts, Bind 28).

The influence of dietary ingredient quality and protein level on gut microbiota composition and microbial metabolites in weanling pigs

Canibe, N., Schönherz, A. A., Lærke, H. N. & Hedemann, M. S., jul. 2022, I: Animal - Science proceedings. 13, 2, s. 203-203 P149.

Positive Selection and Adaptive Introgression of Haplotypes from Bos indicus Improve the Modern Bos taurus Cattle

Zhang, Q., Schönherz, A. A., Lund, M. S. & Guldbrandtsen, B., jun. 2022, I: Agriculture (Switzerland). 12, 6, 844.

Large-scale mitogenome sequencing reveals consecutive expansions of domestic taurine cattle and supports sporadic aurochs introgression

Cubric-Curik, V., Novosel, D., Brajkovic, V., Stabelli, O. R., Krebs, S., Solkner, J., Salamon, D., Ristov, S., Berger, B., Trivizaki, S., Bizelis, I., Ferencakovic, M., Rothammer, S., Kunz, E., Simcic, M., Dovc, P., Bunevski, G., Bytyqi, H., Markovic, B., Brka, M., & 12 flereKume, K., Stojanovid, S., Nikolov, V., Zinovieva, N., Schonherz, A. A., Guldbrandtsen, B., Cacic, M., Radovic, S., Miracle, P., Vernesi, C., Curik, I. & Medugorac, I., apr. 2022, I: Evolutionary Applications. 15, 4, s. 663-678 16 s.

Diet and microbiota-gut-brain axis in relation to tail biting in pigs: A review

Kobek-Kjeldager, C., Schönherz, A. A., Canibe, N. & Pedersen, L. J., jan. 2022, I: Applied Animal Behaviour Science. 246, 14 s., 105514.

Impact of Dietary Sodium Butyrate and Salinomycin on Performance and Intestinal Microbiota in a Broiler Gut Leakage Model

Naghizadeh, M., Klaver, L., Schönherz, A. A., Rani, S., Dalgaard, T. S. & Engberg, R. M., jan. 2022, I: Animals. 12, 1, 23 s., 111.

Review on Preventive Measures to Reduce Post-Weaning Diarrhoea in Piglets

Canibe, N., Højberg, O., Kongsted, H., Vodolazs'ka, D., Lauridsen, C., Nielsen, T. S. & Schönherz, A. A., 2022, I: Animals. 12, 19, 71 s., 2585.

Genomic inbreeding and selection signatures in the local dairy breed Icelandic Cattle

Gautason, E., Schönherz, A. A., Sahana, G. & Guldbrandtsen, B., jun. 2021, I: Animal Genetics. 52, 3, s. 251-262 12 s.

Effect of Maternal Dietary Redox Levels on Antioxidative Status and Immunity of the Suckling Off-Spring

Lauridsen, C., Schönherz, A. A. & Højsgaard, S., mar. 2021, I: Antioxidants. 10, 3, s. 1-13 12 s., 478.

Assessing the genetic background and genomic relatedness of red cattle populations originating from Northern Europe

Schmidtmann, C., Schönherz, A., Guldbrandtsen, B., Marjanovic, J., Calus, M., Hinrichs, D. & Thaller, G., 2021, I: Genetics Selection Evolution. 53, 1, 18 s., 23.

Genetic diversity in Iranian indigenous sheep vis-à-vis selected exogenous sheep breeds and wild mouflon

Eydivandi, S., Sahana, G., Momen, M., Moradi, M. H. & Schönherz, A. A., okt. 2020, I: Animal Genetics. 51, 5, s. 772-787 16 s.

Population structure and genetic characterization of two native Danish sheep breeds

Schonherz, A. A., Szekeres, B. D., Nielsen, V. H. & Guldbrandtsen, B., apr. 2020, I: Acta Agriculturae Scandinavica, Section A - Animal Science. 69, 1-2, s. 53-67

Relationship of Icelandic cattle with Northern and Western European cattle breeds, admixture and population structure

Gautason, E., Schonherz, A. A., Sahana, G. & Guldbrandtsen, B., apr. 2020, I: Acta Agriculturae Scandinavica, Section A - Animal Science. 69, 1-2, s. 25-38

Genomic assessment of suitability of pigs for inclusion in the Pied Danish Pig conservation program – A case study

Guldbrandtsen, B., Nielsen, V. H. & Schönherz, A. A., mar. 2020, I: Acta Agriculturae Scandinavica, Section A - Animal Science. 69, 1-2, s. 95-100

Normal myeloid progenitor cell subsetassociated gene signatures for acute myeloid leukaemia subtyping with prognostic impact

Schonherz, A. A., Bødker, J. S., Schmitz, A., Brøndum, R. F., Jakobsen, L. H., Roug, A. S., Severinsen, M. T., El-Galaly, T. C., Jensen, P., Johnsen, H. E., Bøgsted, M. & Dybkær, K., 2020, I: PLOS ONE. 15, 4, 21 s., e0229593.

Expression of NOTCH3 exon 16 differentiates Diffuse Large B-cell Lymphoma into molecular subtypes and is associated with prognosis

Jespersen, D. S., Schönherz, A. A., Due, H., Bøgsted, M., Sondergaard, T. E. & Dybkær, K., dec. 2019, I: Scientific Reports. 9, 11 s., 335.

MicroRNA-155 controls vincristine sensitivity and predicts superior clinical outcome in diffuse large B-cell lymphoma

Due, H., Schönherz, A. A., Ryø, L., Primo, M. N., Jespersen, D. S., Thomsen, E. A., Roug, A. S., Xiao, M., Tan, X., Pang, Y., Young, K. H., Bøgsted, M., Mikkelsen, J. G. & Dybkær, K., 9 apr. 2019, I: Blood Advances. 3, 7, s. 1185-1196 12 s.

High CXCR4 expression impairs rituximab response and the prognosis of R-CHOP-treated diffuse large B-cell lymphoma patients

Laursen, M. B., Reinholdt, L., Schönherz, A. A., Due, H., Jespersen, D. S., Grubach, L., Ettrup, M. S., Røge, R., Falgreen, S., Sørensen, S., Bødker, J. S., Schmitz, A., Johnsen, H. E., Bøgsted, M. & Dybkær, K., 22 jan. 2019, I: OncoTarget. 10, 7, s. 717-731 15 s.

A multiple myeloma classification system that associates normal B-cell subset phenotypes with prognosis

Bødker, J. S., Brøndum, R. F., Schmitz, A., Schönherz, A. A., Jespersen, D. S., Sønderkær, M., Vesteghem, C., Due, H., Nørgaard, C. H., Perez-Andres, M., Samur, M. K., Davies, F., Walker, B., Pawlyn, C., Kaiser, M., Johnson, D., Bertsch, U., Broyl, A., van Duin, M., Shah, R., & 12 flereJohansen, P., Nørgaard, M. A., Samworth, R. J., Sonneveld, P., Goldschmidt, H., Morgan, G. J., Orfao, A., Munshi, N., Johnson, H. E., El-Galaly, T., Dybkær, K. & Bøgsted, M., 25 sep. 2018, I: Blood Advances. 2, 18, s. 2400-2411 12 s.

Introduction of Viral Hemorrhagic Septicemia Virus into Freshwater Cultured Rainbow Trout Is Followed by Bursts of Adaptive Evolution

Schönherz, A. A., Forsberg, R., Guldbrandtsen, B., Buitenhuis, A. J. & Einer-Jensen, K., 2018, I: Journal of Virology. 92, 12, 20 s., e00436-18.

Ultra-deep sequencing of VHSV isolates contributes to understanding the role of viral quasispecies

Schönherz, A. A., Lorenzen, N., Guldbrandtsen, B., Buitenhuis, B. & Einer-Jensen, K., 8 jan. 2016, I: Veterinary Research. 47, 10, 12 s., 10.

Inter-species transmission of viral hamoerrhagic septicaemia virus (VHSV) from turbot (Scophtalmus maximus) to rainbow trout (Onchorhyncus mykiss)

Schönherz, A., Lorenzen, N. & Einer-Jensen, K., apr. 2013, I: Journal of General Virology. 94, 4, s. 869-875 7 s.

Oral transmission as a route of infection for viral haemorrhagic septicaemia virus in rainbow trout, Oncorhynchus mykiss (Walbaum)

Schönherz, A. A., Hansen, M. H. H., Jørgensen, H. B. H., Berg, P., Lorenzen, N. & Einer-Jensen, K., jun. 2012, I: Journal of Fish Diseases. 35, 6, s. 395-406 12 s.


Dansk Korthornsavl i Fremtiden – Genomisk Kortlægning af Korthornpopulatione - Slutrapport

Schönherz, A. A., mar. 2021, København: Landbrugsstyrelsen. 2 s.

Gamle danske husdyrracers genomer - Racernes oprindelse og slægtskab

Szekeres, B. D., Schönherz, A., Nielsen, V. H. & Guldbrandtsen, B., aug. 2016, DCA - Nationalt Center for Fødevarer og Jordbrug,. 64 s. (DCA rapport; Nr. 082).

Genomic characterization of Danish farm animal genetic resources

Schönherz, A., Nielsen, V. H., Sørensen, A. C. & Guldbrandtsen, B., 31 aug. 2015, Book of Abstracts of the 66th Annual Meeting of the European Federation of Animal Science. The Netherlands: Wageningen Academic Publishers, Bind 21. s. 104-104 1 s. (EAAP Book of Abstracts).

Genetic markers of virulence in a fish rhabdovirus

Schönherz, A., Einer-Jensen, K., Hansen, M. H. H. & Buitenhuis, B., 1 nov. 2012. 1 s.

Inter-Species Transmission of viral haemorrhagic septicaemia virus between marine and freshwater fishes

Schönherz, A., Lorenzen, N. & Einer-Jensen, K., jun. 2012. 1 s.

Inter-species transmission of viral haemorrhagic septicaemia virus between turbot (Scophthalmus maximus) and rainbow trout (Onchorhynchus mykiss)

Schönherz, A., Lorenzen, N. & Einer-Jensen, K., jun. 2012. 1 s.