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Alexander Schmitz

Generation of a predictive melphalan resistance index by drug screen of B-cell cancer cell lines

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

Standard

Generation of a predictive melphalan resistance index by drug screen of B-cell cancer cell lines. / Bøgsted, Martin; Holst, Johanne Marie; Fogd, Kirsten et al.

I: P L o S One, Bind 6, Nr. 4, 01.01.2011, s. e19322.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

Harvard

Bøgsted, M, Holst, JM, Fogd, K, Larsen, SF, Sørensen, S, Schmitz, A, Bukh, A, Johnsen, HE, Nyegaard, M & Dybkær, K 2011, 'Generation of a predictive melphalan resistance index by drug screen of B-cell cancer cell lines', P L o S One, bind 6, nr. 4, s. e19322. https://doi.org/10.1371/journal.pone.0019322

APA

Bøgsted, M., Holst, J. M., Fogd, K., Larsen, S. F., Sørensen, S., Schmitz, A., Bukh, A., Johnsen, H. E., Nyegaard, M., & Dybkær, K. (2011). Generation of a predictive melphalan resistance index by drug screen of B-cell cancer cell lines. P L o S One, 6(4), e19322. https://doi.org/10.1371/journal.pone.0019322

CBE

Bøgsted M, Holst JM, Fogd K, Larsen SF, Sørensen S, Schmitz A, Bukh A, Johnsen HE, Nyegaard M, Dybkær K. 2011. Generation of a predictive melphalan resistance index by drug screen of B-cell cancer cell lines. P L o S One. 6(4):e19322. https://doi.org/10.1371/journal.pone.0019322

MLA

Bøgsted, Martin et al. "Generation of a predictive melphalan resistance index by drug screen of B-cell cancer cell lines". P L o S One. 2011, 6(4). e19322. https://doi.org/10.1371/journal.pone.0019322

Vancouver

Bøgsted M, Holst JM, Fogd K, Larsen SF, Sørensen S, Schmitz A et al. Generation of a predictive melphalan resistance index by drug screen of B-cell cancer cell lines. P L o S One. 2011 jan. 1;6(4):e19322. doi: 10.1371/journal.pone.0019322

Author

Bøgsted, Martin ; Holst, Johanne Marie ; Fogd, Kirsten et al. / Generation of a predictive melphalan resistance index by drug screen of B-cell cancer cell lines. I: P L o S One. 2011 ; Bind 6, Nr. 4. s. e19322.

Bibtex

@article{51a3640ea60d471ba0d267d1707c7a4a,
title = "Generation of a predictive melphalan resistance index by drug screen of B-cell cancer cell lines",
abstract = "Recent reports indicate that in vitro drug screens combined with gene expression profiles (GEP) of cancer cell lines may generate informative signatures predicting the clinical outcome of chemotherapy. In multiple myeloma (MM) a range of new drugs have been introduced and now challenge conventional therapy including high dose melphalan. Consequently, the generation of predictive signatures for response to melphalan may have a clinical impact. The hypothesis is that melphalan screens and GEPs of B-cell cancer cell lines combined with multivariate statistics may provide predictive clinical information.",
author = "Martin B{\o}gsted and Holst, {Johanne Marie} and Kirsten Fogd and Larsen, {Steffen Falgreen} and Suzette S{\o}rensen and Alexander Schmitz and Anne Bukh and Johnsen, {Hans Erik} and Mette Nyegaard and Karen Dybk{\ae}r",
year = "2011",
month = jan,
day = "1",
doi = "10.1371/journal.pone.0019322",
language = "English",
volume = "6",
pages = "e19322",
journal = "P L o S One",
issn = "1932-6203",
publisher = "public library of science",
number = "4",

}

RIS

TY - JOUR

T1 - Generation of a predictive melphalan resistance index by drug screen of B-cell cancer cell lines

AU - Bøgsted, Martin

AU - Holst, Johanne Marie

AU - Fogd, Kirsten

AU - Larsen, Steffen Falgreen

AU - Sørensen, Suzette

AU - Schmitz, Alexander

AU - Bukh, Anne

AU - Johnsen, Hans Erik

AU - Nyegaard, Mette

AU - Dybkær, Karen

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Recent reports indicate that in vitro drug screens combined with gene expression profiles (GEP) of cancer cell lines may generate informative signatures predicting the clinical outcome of chemotherapy. In multiple myeloma (MM) a range of new drugs have been introduced and now challenge conventional therapy including high dose melphalan. Consequently, the generation of predictive signatures for response to melphalan may have a clinical impact. The hypothesis is that melphalan screens and GEPs of B-cell cancer cell lines combined with multivariate statistics may provide predictive clinical information.

AB - Recent reports indicate that in vitro drug screens combined with gene expression profiles (GEP) of cancer cell lines may generate informative signatures predicting the clinical outcome of chemotherapy. In multiple myeloma (MM) a range of new drugs have been introduced and now challenge conventional therapy including high dose melphalan. Consequently, the generation of predictive signatures for response to melphalan may have a clinical impact. The hypothesis is that melphalan screens and GEPs of B-cell cancer cell lines combined with multivariate statistics may provide predictive clinical information.

U2 - 10.1371/journal.pone.0019322

DO - 10.1371/journal.pone.0019322

M3 - Journal article

C2 - 21559449

VL - 6

SP - e19322

JO - P L o S One

JF - P L o S One

SN - 1932-6203

IS - 4

ER -