Mortality in individuals with disruptive behavior disorders diagnosed by specialist services - A nationwide cohort study

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Mortality in individuals with disruptive behavior disorders diagnosed by specialist services - A nationwide cohort study. / Scott, James G; Giørtz Pedersen, Marianne; Erskine, Holly E; Bikic, Aida; Demontis, Ditte; McGrath, John J; Dalsgaard, Søren.

In: Psychiatry Research, Vol. 251, 13.02.2017, p. 255-260.

Publication: Research - peer-reviewJournal article

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Scott, James G; Giørtz Pedersen, Marianne; Erskine, Holly E; Bikic, Aida; Demontis, Ditte; McGrath, John J; Dalsgaard, Søren / Mortality in individuals with disruptive behavior disorders diagnosed by specialist services - A nationwide cohort study.

In: Psychiatry Research, Vol. 251, 13.02.2017, p. 255-260.

Publication: Research - peer-reviewJournal article

Bibtex

@article{587170d39f5b440c8684424df8686d22,
title = "Mortality in individuals with disruptive behavior disorders diagnosed by specialist services - A nationwide cohort study",
keywords = "Journal Article",
author = "Scott, {James G} and {Giørtz Pedersen}, Marianne and Erskine, {Holly E} and Aida Bikic and Ditte Demontis and McGrath, {John J} and Søren Dalsgaard",
note = "Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.",
year = "2017",
month = "2",
doi = "10.1016/j.psychres.2017.02.029",
volume = "251",
pages = "255--260",
journal = "Psychiatry Research",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd.",

}

RIS

TY - JOUR

T1 - Mortality in individuals with disruptive behavior disorders diagnosed by specialist services - A nationwide cohort study

AU - Scott,James G

AU - Giørtz Pedersen,Marianne

AU - Erskine,Holly E

AU - Bikic,Aida

AU - Demontis,Ditte

AU - McGrath,John J

AU - Dalsgaard,Søren

N1 - Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

PY - 2017/2/13

Y1 - 2017/2/13

N2 - Disruptive behavior disorders (DBDs), inclusive of oppositional defiant disorder (ODD) and conduct disorder (CD), are associated with outcomes likely to increase risk of mortality. Using Danish National Registers, a total of 1.92 million individuals including 9495 individuals with DBDs diagnosed by specialist services were followed from their first birthday to 2013. Those with and without DBDs were compared using mortality rate ratios (MRRs) estimated using Poisson regression and adjusted for calendar period, age, sex, family history of psychiatric disorders, maternal age at time of birth, paternal age at time of birth, parental education status, and parental employment status. Over the course of follow up, which totalled 24.9 million person-years, 5580 cohort members died including 78 individuals with DBDs. The mortality rate per 10,000 person-years was 9.66 for individuals with DBDs compared to 2.22 for those with no diagnosis. This corresponded to a fully adjusted MRR of 2.57 (95% confidence interval 2.04-3.20). Comorbid substance use disorder and attention-deficit/hyperactivity disorder resulted in the highest MRR across all categories. These findings demonstrate the excess mortality associated with DBDs.

AB - Disruptive behavior disorders (DBDs), inclusive of oppositional defiant disorder (ODD) and conduct disorder (CD), are associated with outcomes likely to increase risk of mortality. Using Danish National Registers, a total of 1.92 million individuals including 9495 individuals with DBDs diagnosed by specialist services were followed from their first birthday to 2013. Those with and without DBDs were compared using mortality rate ratios (MRRs) estimated using Poisson regression and adjusted for calendar period, age, sex, family history of psychiatric disorders, maternal age at time of birth, paternal age at time of birth, parental education status, and parental employment status. Over the course of follow up, which totalled 24.9 million person-years, 5580 cohort members died including 78 individuals with DBDs. The mortality rate per 10,000 person-years was 9.66 for individuals with DBDs compared to 2.22 for those with no diagnosis. This corresponded to a fully adjusted MRR of 2.57 (95% confidence interval 2.04-3.20). Comorbid substance use disorder and attention-deficit/hyperactivity disorder resulted in the highest MRR across all categories. These findings demonstrate the excess mortality associated with DBDs.

KW - Journal Article

U2 - 10.1016/j.psychres.2017.02.029

DO - 10.1016/j.psychres.2017.02.029

M3 - Journal article

VL - 251

SP - 255

EP - 260

JO - Psychiatry Research

T2 - Psychiatry Research

JF - Psychiatry Research

SN - 0165-1781

ER -