Prevalence and association of oral candidiasis with dysphagia in individuals with acquired brain injury (ABI)

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Objective: To describe the prevalence of oral candidiasis (OC) in individuals with acquired brain injury (ABI) and to evaluate the association of OC with improvement in dysphagia.
Design: Longitudinal observational study.
Methods: Individuals with ABI admitted to a rehabilitation centre were recruited over a one-year period. OC-data were collected by clinical examinations and verified by cultivation/microscopy in every 3 weeks during first 10 weeks of admission. Data on dysphagia were collected through medical record reviews. Dysphagia improvement was defined by: 1) First positive change in food consistency, 2) Initiation of at least soft food consistency. Individuals with and without OC were compared using multivariable Cox proportional hazards regression.
Results: The overall OC prevalence in all individuals and in individuals not treated with antifungal agents were 32.5% and 29.7%, respectively. The OC prevalence was 24.8% after one week of admission and reduced to 10.1% after ten weeks of admission. Adjusted hazard ratios for improvement in dysphagia were 0.64-0.77 in OC compared to without OC, though not statistically significant.
Conclusion: Prevalence of OC was high at admission but reduced during rehabilitation. Though non-significant, the negative trend between OC and improvement in dysphagia suggest that OC may delay the rehabilitation of dysphagia.
Original languageEnglish
Publication year22 Sep 2017
StatePublished - 22 Sep 2017
EventEuropean Society for swallowing disorders - Palau de Congressos de Catalunya (PCC) Av. Diagonal, 661-671, Barcelona, Spain
Duration: 20 Sep 201723 Sep 2017


ConferenceEuropean Society for swallowing disorders
LocationPalau de Congressos de Catalunya (PCC) Av. Diagonal, 661-671
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