Unbiased estimation of particle number using sections--an historical perspective with special reference to the stereology of glomeruli.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  • Stereological Research Laboratory
  • Institute of Clinical Medicine
  • The Department of Pathology - ÅKH
Methods for estimating particle number may be based on at least three different principles. Two of them, isolation of particles and indirect counting, have been predominant until recently. The new methods based on section pairs (disectors) are unbiased and far more efficient. The three principles and their historical developments are described, emphasizing that the newly developed principles have old roots, which were forgotten until recently. It is concluded, that 'learned societies' combined with individual enthusiasm are material for the spread and development of new ideas.
Udgivelsesdato: 1989-Jan
Original languageEnglish
JournalJournal of Microscopy
Volume153
Issue numberPt 1
Pages (from-to)93-102
Number of pages9
ISSN0022-2720
StatePublished - 1989

    Research areas

  • Anatomy, History, 19th Century, History, 20th Century, Kidney Glomerulus, Mathematics, Microtomy

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ID: 10801938