The efficacy of psychoeducation on recurrent depression: A randomised trial with a two-year follow-up

Research output: Research - peer-reviewJournal article


  • Jørgen Aagaard
  • Leslie Foldager
  • Ahmad Makki
    Ahmad MakkiUnit for Psychiatric Research, Aalborg Psychiatric Hospital, Aalborg University HospitalDenmark
  • Vibeke Hansen
    Vibeke HansenAarhus University Hospital, RisskovDenmark
  • Klaus Müller-Nielsen
    Klaus Müller-NielsenDepartment for Child and Youth Psychiatry, Kolding Hospital, KoldingDenmark
The efficacy of psychoeducation is well documented in the treatment of relapse prevention of schizophrenia, and recently also in bipolar disorder; however, for recurrent depression only few controlled studies focusing on the efficacy of psychoeducation have been conducted.
This randomized study tests the efficacy of treatment-as-usual supplemented with a psychoeducative programme for patients with recurrent depression, treated at Community Mental Health Centres (CMHC) in Denmark. The primary outcome measurements concern was decline in consumption of psychiatric inpatient services and decline in Beck’s Depression Inventory (BDI).
Eighty patients were randomized, either to the psychoeducative programme (consisting of eight sessions, each of 2 hours duration) and 2-year outpatient follow-up (42 cases), or only to 2-year outpatient follow-up (38 controls). The patients were monitored during 2 years after randomization. Data were collected from interviews including BDI, drug treatment and social measurements, and register data concerning use of psychiatric services.
At 2-year follow-up, a significant reduction in the consumption of psychiatric inpatient services and in BDI was found; however, it was uniform for case and control patients. Drop-out/non-compliance was significantly more frequent among patients randomized to the control group. Furthermore, during
follow-up the case group got a significant stronger attachment to the Labour market than the control group.
The primary hypothesis could not be confirmed. Secondary outcome measurements concerning drop-out/non-compliance and attachment to the Labour market were significantly in favour of cases.
Original languageEnglish
JournalNordic Journal of Psychiatry
Issue number3
Pages (from-to)223-229
StatePublished - 20 Mar 2017

    Research areas

  • Randomized study, recurrent depression, non-compliance, drop-out, psychoeducation

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