Impact of isoniazid preventive therapy on mortality among children less than 5 years old following exposure to tuberculosis at home in Guinea-Bissau: a prospective cohort study

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  • Victor Francisco Gomes
  • ,
  • Andreas Andersen
  • ,
  • Grethe Lemvik
  • ,
  • Christian Wejse
  • Ines Oliveira
  • ,
  • Fina J Vieira
  • ,
  • Luis José Carlos
  • ,
  • Cesaltina da Silva Vieira
  • ,
  • Peter Aaby, SUND ph.d. skole, Denmark
  • Per Gustafson
In a cohort of children less than 5 years old exposed to adult intrathoracic tuberculosis (TB) in 1996-1998, we found 66% increased mortality compared with community controls. In 2005, we implemented isoniazid preventive therapy (IPT) for children exposed to TB at home, and the present study evaluates the effect of this intervention on mortality.
Original languageEnglish
JournalB M J Open
Pages (from-to)e001545
Publication statusPublished - Mar 2013

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ID: 53670145