Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

    Sarah Felice Evans, Krithi Irmady, Katya Ostrow, Taeho Kim,
  • Anders Nykjaer
  • Paul Saftig, Carl Blobel, Barbara L Hempstead
Original languageEnglish
JournalJournal of Biological Chemistry
Issue number34
Pages (from-to)29556-67
Number of pages12
StatePublished - 2011

    Research areas

  • ADAM Proteins, Adaptor Proteins, Vesicular Transport, Amino Acid Motifs, Amyloid Precursor Protein Secretases, Animals, Brain-Derived Neurotrophic Factor, Golgi Apparatus, HEK293 Cells, Humans, Lysosomes, Membrane Proteins, Mice, Mice, Knockout, Nerve Tissue Proteins, Neurons, Protein Structure, Tertiary, Protein Transport, Rats

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ID: 43877778