Behaviour of [11C]R(-)- and [11C]S(+)-rolipram in vitro and in vivo, and their use as PET radiotracers for the quantificative assay of PDE4

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

    Christine A Parker, Julian C Matthews, Roger N Gunn, Laurent Martarello, Vincent J Cunningham, David Dommett, Stephen T Knibb,
  • Dirk Bender
  • Steen Jakobsen
  • John Brown, Antony D Gee
Original languageEnglish
Issue number4
Pages (from-to)270-9
Number of pages10
StatePublished - 2005

    Research areas

  • 3',5'-Cyclic-AMP Phosphodiesterases, Affinity Labels, Animals, Binding, Competitive, Brain, Carbon Radioisotopes, Cell Membrane, Cyclic AMP, Cyclic Nucleotide Phosphodiesterases, Type 4, Male, Phosphodiesterase Inhibitors, Positron-Emission Tomography, Rats, Rats, Sprague-Dawley, Rolipram, Stereoisomerism, Subcellular Fractions, Sus scrofa

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