General theory for stochastic admixture graphs and F-statistics

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  • Samuele Soraggi
  • Carsten Wiuf, Department of Mathematical Sciences, University of Copenhagen, Denmark
We provide a general mathematical framework based on the theory of graphical models to study admixture graphs. Admixture graphs are used to describe the ancestral relationships between past and present populations, allowing for population merges and migration events, by means of gene flow. We give various mathematical properties of admixture graphs with particular focus on properties of the so-called -statistics. Also the Wright–Fisher model is studied and a general expression for the loss of heterozygosity is derived.
Original languageEnglish
JournalTheoretical Population Biology
Volume125
Pages (from-to)56-66
ISSN0040-5809
DOIs
Publication statusPublished - 1 Feb 2019
Externally publishedYes

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