Ex-vivo diffusion MRI reveals microstructural alterations in stress-sensitive brain regions: A chronic mild stress recovery study

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Ex-vivo diffusion MRI reveals microstructural alterations in stress-sensitive brain regions: A chronic mild stress recovery study. / Khan, Ahmad Raza; Hansen, Brian; Wiborg, Ove; Kroenke, Christopher; Jespersen, Sune.

2018. Abstract from Joint ISMRM and ESMRMB conference, Paris, Paris, France.

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Khan, AR, Hansen, B, Wiborg, O, Kroenke, C & Jespersen, S 2018, 'Ex-vivo diffusion MRI reveals microstructural alterations in stress-sensitive brain regions: A chronic mild stress recovery study' Joint ISMRM and ESMRMB conference, Paris, Paris, France, 16/06/2018 - 21/06/2018, .

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@conference{8c2c319a124d41d8b60386572c619d1e,
title = "Ex-vivo diffusion MRI reveals microstructural alterations in stress-sensitive brain regions: A chronic mild stress recovery study",
abstract = "Depression is a leading cause of disability worldwide and causes significant microstructural alterations in stress-sensitive brain regions.However, the potential recovery of these microstructural alterations has not previously been investigated, which we, therefore, set out to dousing diffusion MRI (d-MRI) in the chronic mild stress (CMS) rat model of depression. This study reveals significant microstructural alterationsafter 8 weeks of recovery, in the opposite direction to change induced by stress in the acute phase of the experiment. Such findings may beuseful in the prognosis of depression or for monitoring treatment response.",
keywords = "Depression, Diffusion MRI, Hippocampus",
author = "Khan, {Ahmad Raza} and Brian Hansen and Ove Wiborg and Christopher Kroenke and Sune Jespersen",
year = "2018",
month = "2",
day = "2",
language = "English",
note = "Joint ISMRM and ESMRMB conference, Paris ; Conference date: 16-06-2018 Through 21-06-2018",

}

RIS

TY - ABST

T1 - Ex-vivo diffusion MRI reveals microstructural alterations in stress-sensitive brain regions: A chronic mild stress recovery study

AU - Khan, Ahmad Raza

AU - Hansen, Brian

AU - Wiborg, Ove

AU - Kroenke, Christopher

AU - Jespersen, Sune

PY - 2018/2/2

Y1 - 2018/2/2

N2 - Depression is a leading cause of disability worldwide and causes significant microstructural alterations in stress-sensitive brain regions.However, the potential recovery of these microstructural alterations has not previously been investigated, which we, therefore, set out to dousing diffusion MRI (d-MRI) in the chronic mild stress (CMS) rat model of depression. This study reveals significant microstructural alterationsafter 8 weeks of recovery, in the opposite direction to change induced by stress in the acute phase of the experiment. Such findings may beuseful in the prognosis of depression or for monitoring treatment response.

AB - Depression is a leading cause of disability worldwide and causes significant microstructural alterations in stress-sensitive brain regions.However, the potential recovery of these microstructural alterations has not previously been investigated, which we, therefore, set out to dousing diffusion MRI (d-MRI) in the chronic mild stress (CMS) rat model of depression. This study reveals significant microstructural alterationsafter 8 weeks of recovery, in the opposite direction to change induced by stress in the acute phase of the experiment. Such findings may beuseful in the prognosis of depression or for monitoring treatment response.

KW - Depression, Diffusion MRI, Hippocampus

M3 - Conference abstract for conference

ER -