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Yousef Yavarian

Mastoiditis and Gradenigo's Syndrome with anaerobic bacteria

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Mastoiditis and Gradenigo's Syndrome with anaerobic bacteria. / Jacobsen, Chris Ladefoged; Bruhn, Mikkel Attermann; Yavarian, Yousef; Gaihede, Michael L.

In: B M C Ear, Nose and Throat Disorders, Vol. 12, No. 1, 2012, p. 10.

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@article{aaa5ef20ada74c9ba0f578ad5dfa72d2,
title = "Mastoiditis and Gradenigo's Syndrome with anaerobic bacteria",
abstract = "ABSTRACT: BACKGROUND: Gradenigo's syndrome is a rare disease, which is characterized by the triad of the following conditions: suppurative otitis media, pain in the distribution of the first and the second division of trigeminal nerve, and abducens nerve palsy. The full triad may often not be present, but can develop if the condition is not treated correctly. CASE PRESENTATION: We report a case of a 3-year-old girl, who presented with fever and left-sided acute otitis media. She developed acute mastoiditis, which was initially treated by intravenous antibiotics, ventilation tube insertion and cortical mastoidectomy. After 6 days the clinical picture was complicated by development of left-sided abducens palsy. MRI-scanning showed osteomyelitis within the petro-mastoid complex, and a hyper intense signal of the adjacent meninges. Microbiological investigations showed Staphylococcus aureus and Fusobacterium necrophorum. She was treated successfully with intravenous broad-spectrum antibiotic therapy with anaerobic coverage. After 8 weeks of follow-up there was no sign of recurrent infection or abducens palsy. CONCLUSION: Gradenigo's syndrome is a rare, but life-threatening complication to middle ear infection. It is most commonly caused by aerobic microorganisms, but anaerobic microorganisms may also be found why anaerobic coverage should be considered when determining the antibiotic treatment.",
author = "Jacobsen, {Chris Ladefoged} and Bruhn, {Mikkel Attermann} and Yousef Yavarian and Gaihede, {Michael L}",
year = "2012",
doi = "10.1186/1472-6815-12-10",
language = "English",
volume = "12",
pages = "10",
journal = "B M C Ear, Nose and Throat Disorders",
issn = "1472-6815",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Mastoiditis and Gradenigo's Syndrome with anaerobic bacteria

AU - Jacobsen, Chris Ladefoged

AU - Bruhn, Mikkel Attermann

AU - Yavarian, Yousef

AU - Gaihede, Michael L

PY - 2012

Y1 - 2012

N2 - ABSTRACT: BACKGROUND: Gradenigo's syndrome is a rare disease, which is characterized by the triad of the following conditions: suppurative otitis media, pain in the distribution of the first and the second division of trigeminal nerve, and abducens nerve palsy. The full triad may often not be present, but can develop if the condition is not treated correctly. CASE PRESENTATION: We report a case of a 3-year-old girl, who presented with fever and left-sided acute otitis media. She developed acute mastoiditis, which was initially treated by intravenous antibiotics, ventilation tube insertion and cortical mastoidectomy. After 6 days the clinical picture was complicated by development of left-sided abducens palsy. MRI-scanning showed osteomyelitis within the petro-mastoid complex, and a hyper intense signal of the adjacent meninges. Microbiological investigations showed Staphylococcus aureus and Fusobacterium necrophorum. She was treated successfully with intravenous broad-spectrum antibiotic therapy with anaerobic coverage. After 8 weeks of follow-up there was no sign of recurrent infection or abducens palsy. CONCLUSION: Gradenigo's syndrome is a rare, but life-threatening complication to middle ear infection. It is most commonly caused by aerobic microorganisms, but anaerobic microorganisms may also be found why anaerobic coverage should be considered when determining the antibiotic treatment.

AB - ABSTRACT: BACKGROUND: Gradenigo's syndrome is a rare disease, which is characterized by the triad of the following conditions: suppurative otitis media, pain in the distribution of the first and the second division of trigeminal nerve, and abducens nerve palsy. The full triad may often not be present, but can develop if the condition is not treated correctly. CASE PRESENTATION: We report a case of a 3-year-old girl, who presented with fever and left-sided acute otitis media. She developed acute mastoiditis, which was initially treated by intravenous antibiotics, ventilation tube insertion and cortical mastoidectomy. After 6 days the clinical picture was complicated by development of left-sided abducens palsy. MRI-scanning showed osteomyelitis within the petro-mastoid complex, and a hyper intense signal of the adjacent meninges. Microbiological investigations showed Staphylococcus aureus and Fusobacterium necrophorum. She was treated successfully with intravenous broad-spectrum antibiotic therapy with anaerobic coverage. After 8 weeks of follow-up there was no sign of recurrent infection or abducens palsy. CONCLUSION: Gradenigo's syndrome is a rare, but life-threatening complication to middle ear infection. It is most commonly caused by aerobic microorganisms, but anaerobic microorganisms may also be found why anaerobic coverage should be considered when determining the antibiotic treatment.

U2 - 10.1186/1472-6815-12-10

DO - 10.1186/1472-6815-12-10

M3 - Journal article

C2 - 22978305

VL - 12

SP - 10

JO - B M C Ear, Nose and Throat Disorders

JF - B M C Ear, Nose and Throat Disorders

SN - 1472-6815

IS - 1

ER -