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Poul Nissen

  1. 2017
  2. E-pub ahead of print

    The Role of TM5 in Na2 Release and the Conformational Transition of Neurotransmitter:Sodium Symporters toward the Inward-Open State. / Stolzenberg, Sebastian; Li, Zheng; Quick, Matthias; Malinauskaite, Lina; Nissen, Poul; Weinstein, Harel; Javitch, Jonathan A; Shi, Lei.

    In: The Journal of biological chemistry, 20.03.2017.

    Publication: Research - peer-reviewJournal article

  3. E-pub ahead of print

    A High and Phosphatidylinositol-4-phosphate (PI4P)-dependent ATPase Activity for the Drs2p/Cdc50p Flippase after Removal of its N- and C-terminal Extensions. / Azouaoui, Hassina; Montigny, Cedric; Dieudonné, Thibaud; Champeil, Philippe; Jacquot, Aurore; Vázquez-Ibar, José Luis; le Maréchal, Pierre; Ulstrup, Jakob; Ash, Miriam-Rose; Lyons, Joseph A; Nissen, Poul; Lenoir, Guillaume.

    In: The Journal of biological chemistry, 16.03.2017.

    Publication: Research - peer-reviewJournal article

  4. Published

    Brief encounters of cytochrome c. / Lyons, Joseph A; Nissen, Poul.

    In: E M B O Journal, Vol. 36, No. 3, 01.02.2017, p. 250-251.

    Publication: ResearchJournal article

  5. 2016
  6. Published

    The molecular mechanism for overcoming the ratelimiting step in monoamine neurotransmitter transport. / Said, Saida; Malinauskaite, Lina; Grouleff, Julie; Shahsavar, Azadeh; Bjerregaard, Henriette; Noer, Pernille Rimmer; Severinsen, Kasper; Boesen, Thomas; Schiøtt, Birgit; Nissen, Poul; Sinning, Steffen.

    2016. Poster session presented at Årsmøde for Dansk Selskab for Farmakologi, Toksikologi og Medicinalkemi, Sandbjerg, Denmark.

    Publication: ResearchPoster

  7. Published
  8. Published
  9. Published

    Expression strategies for structural studies of eukaryotic membrane proteins. / Lyons, Joseph A; Shahsavar, Azadeh; Paulsen, Peter Aasted; Pedersen, Bjørn Panyella; Nissen, Poul.

    In: Current Opinion in Structural Biology, Vol. 38, 27.06.2016, p. 137-144.

    Publication: Research - peer-reviewJournal article

  10. Published

    Crystal Structure of the Vanadate-Inhibited Ca2+-ATPase. / Clausen, Johannes D.; Bublitz, Maike; Arnou, Bertrand Jean-Paul; Olesen, Claus; Andersen, Jens Peter; Møller, Jesper Vuust; Nissen, Poul.

    In: Structure, Vol. 24, No. 4, 05.04.2016, p. 617-623.

    Publication: Research - peer-reviewJournal article

  11. Published

    Isolation, crystallization and crystal structure determination of bovine kidney Na+,K+-ATPase. / Lindholt, Jonas; Mattle, Daniel; Fedosova, Natalya; Nissen, Poul; Schuldt, Linda.

    In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, Vol. 72, No. Pt. 4, 01.04.2016, p. 282-287.

    Publication: Research - peer-reviewJournal article

  12. Published

    Initiating heavy-atom-based phasing by multi-dimensional molecular replacement. / Pedersen, Bjørn Panyella; Gourdon, Pontus; Liu, Xiangyu; Karlsen, Jesper Lykkegaard; Nissen, Poul.

    In: Acta crystallographica. Section D. Structural biology , Vol. 72, No. Pt 3, 01.03.2016, p. 440-445.

    Publication: Research - peer-reviewJournal article

  13. Published

    Crystal Structure of an Ammonia-Permeable Aquaporin. / Kirscht, Andreas; Kaptan, Shreyas S; Bienert, Gerd Patrick; Chaumont, François; Nissen, Poul; de Groot, Bert L; Kjellbom, Per; Gourdon, Pontus; Johanson, Urban.

    In: PLoS Biology, Vol. 14, No. 3, 03.2016, p. e1002411.

    Publication: Research - peer-reviewJournal article

  14. Published

    Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model. / Bøttger, Pernille; Pedersen, Simon Glerup; Gesslein, Bodil; Illarionova, Nina; Isaksen, Toke Jost; Heuck, Anders; Clausen, Bettina Hjelm; Füchtbauer, Ernst-Martin; Gramsbergen, Jan Bert; Gunnarson, Eli; Aperia, Anita; Lauritzen, Martin; Lambertsen, Kate Lykke; Nissen, Poul; Lykke-Hartmann, Karin.

    In: Scientific Reports, Vol. 6, No. 22047, 25.02.2016.

    Publication: Research - peer-reviewJournal article

  15. Published

    Reappraising the effects of artemisinin on the ATPase activity of PfATP6 and SERCA1a E255L expressed in Xenopus laevis oocytes. / David-Bosne, Stéphanie; Voldsgaard Clausen, Michael; Poulsen, Hanne; Møller, Jesper Vuust; Nissen, Poul; le Maire, Marc.

    In: Nature Structural and Molecular Biology, Vol. 23, No. 1, 06.01.2016, p. 1-2.

    Publication: Research - peer-reviewJournal article

  16. Published
  17. Published

    An Introduction to P-type ATPase Research. / Nissen, Poul.

    P-Type ATPases : Methods and Protocols. ed. / Maike Bublitz. Vol. 1377 Springer, 2016. p. 1-2 (Methods in molecular biology (Clifton, N.J.)).

    Publication: ResearchBook chapter

  18. Published
  19. Published

    Engineering a prototypic P-type ATPase Listeria Monocytogenes Ca(2+)-ATPase 1 for single-molecule FRET studies. / Dyla, Mateusz; Andersen, Jacob; Kjaergaard, Magnus; Birkedal, Victoria; Terry, Daniel S.; Altman, Roger B.; Blanchard, Scott; Nissen, Poul; Knudsen, Charlotte R.

    In: Bioconjugate Chemistry, Vol. 27, No. 9, 2016, p. 2176-2187.

    Publication: Research - peer-reviewJournal article

  20. Published

    Misbrug af naturvidenskab i demokratidebatten: Den "kolde vinter-teori" er videnskabeligt fupmageri. / Füchtbauer, Ernst-Martin; Kjærgaard, Peter C.; Nissen, Poul; Wang, Tobias; Willerslev, Eske; Zahavi, Dan.

    In: Jyllands-Posten. 2016 ; 29.11. 2016, 01 January 2016.

    Publication: CommunicationComment/debate

  21. Published

    On the molecular mechanism of flippase- and scramblase-mediated phospholipid transport. / Montigny, Cédric; Lyons, Joseph; Champeil, Philippe; Nissen, Poul; Lenoir, Guillaume.

    In: B B A - Molecular and Cell Biology of Lipids, Vol. 1861, No. 8, Part B, 2016.

    Publication: Research - peer-reviewJournal article

  22. Published

    Reconstitution of Na,K-ATPase in Nanodiscs. / Gregersen, Jonas Lindholt; Fedosova, Natalya; Nissen, Poul; Boesen, Thomas.

    In: Methods in Molecular Biology, Vol. 1377, 2016, p. 403-409.

    Publication: Research - peer-reviewJournal article

  23. Published

    The α4 isoform of the Na+ ,K+ -ATPase is tuned for changing extracellular environments. / Voldsgaard Clausen, Michael; Nissen, Poul; Poulsen, Hanne.

    In: The F E B S Journal (Online), Vol. 283, No. 2, 2016, p. 282-293.

    Publication: Research - peer-reviewJournal article

  24. Published

    Tuning of the Na,K-ATPase by the beta subunit. / Hilbers, Florian; Kopec, Wojciech; Isaksen, Toke Jost; Holm, Thomas Hellesøe; Lykke-Hartmann, Karin; Nissen, Poul; Khandelia, Himanshu; Poulsen, Hanne.

    In: Scientific Reports, Vol. 6, No. 20442, 2016.

    Publication: Research - peer-reviewJournal article

  25. 2015
  26. Published

    Regulation of the Ca(2+)-ATPase by cholesterol : A specific or non-specific effect? / Autzen, Henriette Elisabeth; Siuda, Iwona; Sonntag, Yonathan; Nissen, Poul; Møller, Jesper Vuust; Thøgersen, Lea.

    In: Molecular Membrane Biology, Vol. 32, No. 3, 11.08.2015, p. 75-87.

    Publication: Research - peer-reviewJournal article

  27. Published

    Structural studies of P-type ATPase-ligand complexes using an X-ray free-electron laser. / Bublitz, Maike; Nass, Karol; Drachmann, Nikolaj D; Markvardsen, Anders J; Gutmann, Matthias J; Barends, Thomas R M; Mattle, Daniel; Shoeman, Robert L; Doak, R Bruce; Boutet, Sébastien; Messerschmidt, Marc; Seibert, Marvin M; Williams, Garth J; Foucar, Lutz; Reinhard, Linda; Sitsel, Oleg; Gregersen, Jonas L; Clausen, Johannes D; Boesen, Thomas; Gotfryd, Kamil; Wang, Kai-Tuo; Olesen, Claus; Møller, Jesper V; Nissen, Poul; Schlichting, Ilme.

    In: IUCrJ, Vol. 2, No. Pt 4, 01.07.2015, p. 409-420.

    Publication: Research - peer-reviewJournal article

  28. Published

    Structure and function of Cu(I)- and Zn(II)-ATPases. / Sitsel, Oleg; Grønberg, Christina; Autzen, Henriette; Wang, Kaituo; Meloni, Gabriele; Nissen, Poul; Gourdon, Pontus.

    In: Biochemistry, Vol. 54, No. 37, 01.07.2015, p. 5673-5683.

    Publication: Research - peer-reviewJournal article

  29. Published

    Against the odds? De novo structure determination of a pilin with two cysteine residues by sulfur SAD. / Gorgel, Manuela; Bøggild, Andreas; Ulstrup, Jakob; Weiss, Manfred S; Müller, Uwe; Nissen, Poul; Boesen, Thomas.

    In: Acta crystallographica. Section D. Structural biology , Vol. 71, No. 5, 05.2015, p. 1095-1101.

    Publication: Research - peer-reviewJournal article

  30. Published

    Targeting thapsigargin towards tumors. / Doan, Nhu Thi Quynh; Paulsen, Eleonora Sandholdt; Sehgal, Pankaj; Møller, Jesper Vuust; Nissen, Poul; Denmeade, Samuel R; Isaacs, John T; Dionne, Craig A; Christensen, Søren Brøgger.

    In: Steroids, Vol. 97, 05.2015, p. 2-7.

    Publication: Research - peer-reviewJournal article

  31. Published

    Indications of radiation damage in ferredoxin microcrystals using high-intensity X-FEL beams. / Nass, Karol; Foucar, Lutz; Barends, Thomas R M; Hartmann, Elisabeth; Botha, Sabine; Shoeman, Robert L; Doak, R Bruce; Alonso-Mori, Roberto; Aquila, Andrew; Bajt, Saša; Barty, Anton; Bean, Richard; Beyerlein, Kenneth R; Bublitz, Maike; Drachmann, Nikolaj; Gregersen, Jonas; Jönsson, H Olof; Kabsch, Wolfgang; Kassemeyer, Stephan; Koglin, Jason E; Krumrey, Michael; Mattle, Daniel; Messerschmidt, Marc; Nissen, Poul; Reinhard (maiden name Schuldt), Linda; Sitsel, Oleg; Sokaras, Dimosthenis; Williams, Garth J; Hau-Riege, Stefan; Timneanu, Nicusor; Caleman, Carl; Chapman, Henry N; Boutet, Sébastien; Schlichting, Ilme.

    In: Journal of Synchrotron Radiation, Vol. 22, No. 2, 03.2015, p. 225-238.

    Publication: Research - peer-reviewJournal article

  32. Published

    Structures and characterization of digoxin- and bufalin-bound Na+,K+-ATPase compared with the ouabain-bound complex. / Laursen, Mette; Gregersen, Jonas Lindholt; Yatime, Laure; Nissen, Poul; Fedosova, Natalya.

    In: PNAS (Proceedings of the National Academy of Sciences of the United States of America), Vol. 112, No. 6, 10.02.2015, p. 1755-1760.

    Publication: Research - peer-reviewJournal article

  33. Published

    A sulfur-based transport pathway in Cu+-ATPases. / Mattle, Daniel; Zhang, Limei; Sitsel, Oleg; Pedersen, Lotte Thue; Moncelli, Maria Rosa; Tadini-Buoninsegni, Francesco; Gourdon, Pontus; Rees, Douglas C; Nissen, Poul; Meloni, Gabriele.

    In: E M B O Reports, 2015, p. 728-740.

    Publication: Research - peer-reviewJournal article

  34. Published

    Digesting New Elements in Peptide Transport. / Lyons, Joseph A; Nissen, Poul.

    In: Structure, Vol. 23, No. 10, 2015, p. 1779-80.

    Publication: Research - peer-reviewJournal article

  35. Published

    Discovery of Tricyclic Clerodane Diterpenes as Sarco/Endoplasmic Reticulum Ca(2+)-ATPase Inhibitors and Structure-Activity Relationships. / de Ford , Christian ; Calderon, Carlos; Sehgal, Pankaj; Fedosova, Natalya; Murillo, Renato ; Olesen, Claus; Nissen, Poul; Møller, Jesper Vuust; Merfort, Irmgard.

    In: Journal of Natural Products, Vol. 78 (6), 2015, p. 1262–1270.

    Publication: Research - peer-reviewJournal article

  36. Published
  37. Published

    Membrane proteins - do we catch up with the breathless pace of soluble protein structural biology? / Pedersen, Bjørn Panyella; Nissen, Poul.

    In: B B A - Molecular and Cell Biology of Lipids, Vol. 1850, No. 3, 2015, p. 447-8.

    Publication: CommunicationJournal article

  38. 2014
  39. Published

    Hydrogen bond rotations as a uniform structural tool for analyzing protein architecture. / Penner, Robert; Andersen, Ebbe Sloth; Jensen, Jens Ledet; Kantcheva, Adriana Krassimirova; Bublitz, Maike; Nissen, Poul; Rasmussen, Anton Michael Havelund; Svane, Katrine Louise; Hammer, Bjørk; Rezazadegan, Reza; Nielsen, Niels Christian; Nielsen, Jakob Toudahl; Andersen, Jørgen Ellegaard.

    In: Nature Communications, Vol. 5, 5803, 17.12.2014.

    Publication: Research - peer-reviewJournal article

  40. Published

    S-Palmitoylation and S-Oleoylation of Rabbit and Pig Sarcolipin. / Montigny, Cédric; Decottignies, Paulette; le Maréchal, Pierre; Capy, Pierre; Bublitz, Maike; Olesen, Claus; Møller, Jesper Vuust; le Maire, Marc; Nissen, Poul.

    In: Journal of Biological Chemistry, Vol. 289, 05.12.2014, p. 33850-33861.

    Publication: Research - peer-reviewJournal article

  41. Published

    Inhibition of Ubiquitin Proteasome System Rescues the Defective Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA1) Protein Causing Chianina Cattle Pseudomyotonia. / Bianchini, Elisa; Testoni, Stefania; Gentile, Arcangelo; Calì, Tito; Ottolini, Denis; Villa, Antonello; Brini, Marisa; Betto, Romeo; Mascarello, Francesco; Sandonà, Dorianna; Sacchetto, Roberta; Nissen, Poul.

    In: Journal of Biological Chemistry, Vol. 289, No. 48, 28.11.2014, p. 33073-33082.

    Publication: Research - peer-reviewJournal article

  42. Published

    A mechanism for intracellular release of Na(+) by neurotransmitter/sodium symporters. / Malinauskaite, Lina; Quick, Matthias; Reinhard, Linda; Lyons, Joseph A; Yano, Hideaki; Javitch, Jonathan A; Nissen, Poul.

    In: Nature Structural and Molecular Biology, Vol. 21, No. 11, 11.2014, p. 1006-1012.

    Publication: Research - peer-reviewJournal article

  43. Published

    Structure and mechanism of Zn2+-transporting P-type ATPases. / Wang, Kaituo; Sitsel, Oleg; Meloni, Gabriele; Autzen, Henriette Elisabeth; Andersson, Magnus; Klymchuk, Tetyana; Nielsen, Anna Marie; Rees, Douglas C; Nissen, Poul; Gourdon, Pontus.

    In: Nature, Vol. 514, No. 7523, 23.10.2014, p. 518-522.

    Publication: Research - peer-reviewJournal article

  44. Published
  45. Published

    The flexibility of the conserved Leu99 is pivotal for overcoming the rate-limiting conformational transition of the human serotonin transporter in serotonin transport. / Said, Saida; Bjerregaard, Henriette; Severinsen, Kasper; Malinauskaite, Lina; Sahin, Caglanur; Nissen, Poul; Sinning, Steffen.

    2014. Poster session presented at Transmembrane Transporters in Health and Disease, Wien, Austria.

    Publication: ResearchPoster

  46. Published

    Crystals of Na(+)/K(+)-ATPase with bound cisplatin. / Huliciak, Miroslav; Reinhard, Linda; Laursen, Mette; Fedosova, Natalya; Nissen, Poul; Kubala, Martin.

    In: Biochemical Pharmacology, Vol. 92, No. 3, 06.09.2014, p. 494-498.

    Publication: Research - peer-reviewJournal article

  47. Published

    Comparing crystal structures of Ca2+-ATPase in the presence of different lipids. / Drachmann, Nikolaj D; Olesen, Claus; Møller, Jesper V; Guo, Zheng; Bublitz, Maike; Nissen, Poul.

    In: F E B S Journal, Vol. 281, No. 18, 09.2014, p. 4249-4262.

    Publication: Research - peer-reviewJournal article

  48. Published
  49. Published

    How do we show molecules and how they move? / Nissen, Poul.

    In: Biozoom, Vol. 3, 07.2014, p. 20-21.

    Publication: CommunicationJournal article

  50. Published

    Methods and tools for identification of rsk/msk kinase inhibitors. / Andersen, Jacob Lauwring (Inventor); Nissen, Poul (Inventor); Iversen, Lars (Inventor); Gesser, Borbala (Inventor).

    IPC No.: C12N15/62; C12N9/12; C30B29/58; G06F19/16. Patent No.: WO2014048442 (A1). Apr 03, 2014.

    Publication: ResearchPatent

  51. Published

    Initiating Heavy-atom Based Phasing by Multi-Dimensional Molecular Replacement. / Pedersen, Bjørn Panyella; Gourdon, Pontus; Liu, Xiangyu; Lykkegaard Karlsen, Jesper; Nissen, Poul.

    In: arXiv, Vol. 1403.7484, 28.03.2014.

    Publication: ResearchJournal article

  52. Published

    Transport Pathway in Cu+ P-Type ATPases. / Andersson, Magnus; Mattle, Daniel; Sitsel, Oleg; Nielsen, Anna Marie; Lindahl, Erik; White, Stephen H.; Nissen, Poul; Gourdon, Pontus.

    In: Biophysical Journal, Vol. 106, No. 2, 28.01.2014, p. 427A-427A.

    Publication: ResearchConference abstract in journal

  53. Published

    Large Scale Identification and Categorization of Protein Sequences Using Structured Logistic Regression. / Pedersen, Bjørn Panella; Ifrim, Georgiana; Liboriussen, Poul; Axelsen, Kristian B.; Palmgren, Michael G.; Nissen, Poul; Wiuf, Carsten Henrik; Pedersen, Christian Nørgaard Storm.

    In: P L o S One, Vol. 9, No. 1, e85139, 20.01.2014.

    Publication: Research - peer-reviewJournal article

  54. Published

    A high-yield co-expression system for the purification of an intact drs2p-cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate. / Azouaoui, Hassina; Montigny, Cédric; Ash, Miriam-Rose; Fijalkowski, Frank; Jacquot, Aurore; Grønberg, Christina; López-Marqués, Rosa L; Palmgren, Michael G; Garrigos, Manuel; le Maire, Marc; Decottignies, Paulette; Gourdon, Pontus; Nissen, Poul; Champeil, Philippe; Lenoir, Guillaume.

    In: PloS one, Vol. 9, No. 11, e112176, 2014.

    Publication: Research - peer-reviewJournal article

  55. Published

    Copper-transporting P-type ATPases use a unique ion-release pathway. / Andersson, Magnus; Mattle, Daniel; Sitsel, Oleg; Klymchuk, Tetyana; Nielsen, Anna Marie; Møller, Lisbeth Birk; White, Stephen H; Nissen, Poul; Gourdon, Pontus.

    In: Nature Structural and Molecular Biology, Vol. 21, 2014, p. 43-48.

    Publication: Research - peer-reviewJournal article

  56. Published

    Na(+),K(+)-ATPase Isoform Selectivity for Digitalis-Like Compounds Is Determined by Two Amino Acids in the First Extracellular Loop. / Weigand, Karl ; Laursen, Mette; Swarts, Herman G.P.; Engwerda, Anthonius H.J.; Prufert, Christian ; Sandrock, Julia ; Nissen, Poul; Fedosova, Natalya; Russel, Frank G.M.; Koenderink, Jan B.

    In: Chemical Research in Toxicology, Vol. 27, No. 12, 2014, p. 2082-2092.

    Publication: Research - peer-reviewJournal article

  57. 2013
  58. Published

    SERCA mutant E309Q binds two Ca ions but adopts a catalytically incompetent conformation. / Clausen, Johannes D.; Bublitz, Maike; Arnou, Bertrand; Montigny, Cédric; Jaxel, Christine; Møller, Jesper Vuust; Nissen, Poul; Andersen, Jens Peter; le Maire, Marc.

    In: E M B O Journal, Vol. 32, No. 24, 11.12.2013, p. 3231-3243.

    Publication: Research - peer-reviewJournal article

  59. Published

    Heterologous expression and purification of an active human TRPV3 ion channel. / Kol, Stefan; Braun, Christian; Thiel, Gerhard; Doyle, Declan A; Sundström, Michael; Gourdon, Pontus; Nissen, Poul.

    In: F E B S Journal, Vol. 280, No. 23, 12.2013, p. 6010–6021.

    Publication: Research - peer-reviewJournal article

  60. Published

    Introduction : Ca(2+) signalling and transport in health and disease. / Tidow, Henning; Nissen, Poul.

    In: F E B S Journal, Vol. 280, No. 21, 11.2013, p. 5384-5384.

    Publication: Research - peer-reviewJournal article

  61. Published

    Probing determinants of cyclopiazonic acid sensitivity of bacterial Ca(2+) -ATPases. / Kotsubei, Aljona; Gorgel, Manuela; Morth, Jens P; Nissen, Poul; Andersen, Jacob Lauwring.

    In: F E B S Journal, Vol. 280, No. 21, 11.2013, p. 5441–5449.

    Publication: Research - peer-reviewJournal article

  62. Published

    Structural diversity of calmodulin binding to its target sites. / Tidow, Henning; Nissen, Poul.

    In: F E B S Journal, Vol. 280, No. 21, 11.2013, p. 5551–5565.

    Publication: Research - peer-reviewJournal article

  63. Published

    Crystal Structure of Na+, K+-ATPase in the Na+-Bound State. / Nyblom, Maria; Poulsen, Hanne; Gourdon, Pontus; Reinhard (maiden name Schuldt), Linda; Andersson, Magnus; Lindahl, Erik; Fedosova, Natalya; Nissen, Poul.

    In: Science, Vol. 342, No. 6154, 04.10.2013, p. 123-127.

    Publication: Research - peer-reviewJournal article

  64. Published

    Identifying ligand-binding hot spots in proteins using brominated fragments. / Grøftehauge, Morten K; Therkelsen, Martin O; Taaning, Rolf; Skrydstrup, Troels; Morth, J Preben; Nissen, Poul.

    In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online, Vol. 69, No. Pt 9, 09.2013, p. 1060-1065.

    Publication: Research - peer-reviewJournal article

  65. Published

    Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. / Azizan, Elena A B; Poulsen, Hanne; Tuluc, Petronel; Zhou, Junhua; Clausen, Michael; Lieb, Andreas; Maniero, Carmela; Garg, Sumedha; Bochukova, Elena G; Zhao, Wanfeng; Shaikh, Lalarukh Haris; Brighton, Cheryl A; Teo, Ada E D; Davenport, Anthony P; Dekkers, Tanja; Tops, Bas; Küsters, Benno; Ceral, Jiri; Yeo, Giles S H; Neogi, Sudeshna Guha; McFarlane, Ian; Rosenfeld, Nitzan; Marass, Francesco; Hadfield, James; Margas, Wojciech; Chaggar, Kanchan; Solar, Miroslav; Deinum, Jaap; Dolphin, Annette C; Farooqi, I Sadaf; Striessnig, Joerg; Nissen, Poul; Brown, Morris J.

    In: Nature genetics, Vol. 45, No. 9, 28.08.2013, p. 1055-1060.

    Publication: Research - peer-reviewJournal article

  66. Published

    On Allosteric Modulation of P-Type Cu+-ATPases. / Mattle, Daniel; Sitsel, Oleg; Autzen, Henriette Elisabeth; Meloni, Gabriele; Gourdon, Pontus; Nissen, Poul.

    In: Journal of Molecular Biology, Vol. 425, No. 13, 10.07.2013, p. 2299-2308.

    Publication: Research - peer-reviewReview

  67. Published

    Crystal structure of the high-affinity Na+,K+-ATPase–ouabain complex with Mg2+ bound in the cation binding site. / Laursen, Mette; Yatime, Laure; Nissen, Poul; Fedosova, Natalya.

    In: National Academy of Sciences. Proceedings, Vol. 110, No. 27, 07.2013, p. 10958–10963.

    Publication: Research - peer-reviewJournal article

  68. Published

    Chloride binding site of neurotransmitter sodium symporters. / Kantcheva, Adriana Krassimirova; Quick, Matthias; Shi, Lei; Winther, Anne-Marie Lund; Stolzenberg, Sebastian; Weinstein, Harel; Javitch, Jonathan A.; Nissen, Poul.

    In: National Academy of Sciences. Proceedings, Vol. 110, No. 21, 21.05.2013, p. 8489-8494.

    Publication: Research - peer-reviewJournal article

  69. Published

    Ion Pathways in the Sarcoplasmic Reticulum Ca2+-ATPase. / Bublitz, Maike; Musgaard, Maria; Poulsen, Hanne; Thøgersen, Lea; Olesen, Claus; Schiøtt, Birgit; Morth, Preben; Møller, Jesper V; Nissen, Poul.

    In: Journal of Biological Chemistry, Vol. 288, 12.04.2013, p. 10759-10765.

    Publication: Research - peer-reviewJournal article

  70. Published

    Water-mediated interactions influence the binding of thapsigargin to sarco/endoplasmic reticulum calcium adenosinetriphosphatase. / Paulsen, Eleonora S; Villadsen, Jesper; Tenori, Eleonora; Liu, Huizhen; Bonde, Ditte Fast; Lie, Mette Alstrup; Bublitz, Maike; Olesen, Claus; Autzen, Henriette Elisabeth; Dach, Ingrid; Sehgal, Pankaj; Nissen, Poul; Møller, Jesper Vuust; Schiøtt, Birgit; Christensen, SB.

    In: Journal of Medicinal Chemistry, Vol. 56, No. 9, 04.2013, p. 3609-3619.

    Publication: Research - peer-reviewJournal article

  71. Published

    The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm. / Winther, Anne-Marie Lund; Bublitz, Maike; Karlsen, Jesper Lykkegaard; Møller, Jesper Vuust; Hansen, John Bondo; Nissen, Poul; Buch-Pedersen, Morten J.

    In: Nature, Vol. 495, No. 7440, 14.03.2013, p. 265-269.

    Publication: Research - peer-reviewLetter

  72. Published

    The C-terminal cavity of the Na,K-ATPase analyzed by docking and electrophysiology. / Paulsen, Peter Aasted; Jurkowski, Wiktor; Apostolov, Rossen; Lindahl, Erik; Nissen, Poul; Poulsen, Hanne.

    In: Molecular Membrane Biology, Vol. 30, No. 2, 03.2013, p. 195-205.

    Publication: Research - peer-reviewJournal article

  73. Published

    Na+,K+-ATPase as a docking station : protein-protein complexes of the Na(+),K (+)-ATPase. / Reinhard (maiden name Schuldt), Linda; Tidow, Henning; Clausen, Michael J; Nissen, Poul.

    In: Cellular and Molecular Life Sciences, Vol. 70, No. 2, 01.2013, p. 205-222.

    Publication: Research - peer-reviewJournal article

  74. 2012
  75. Published

    Active Detergent-solubilized H+,K+-ATPase Is a Monomer. / Dach, Ingrid; Olesen, Claus; Signor, Luca; Nissen, Poul; le Maire, Marc; Møller, Jesper V; Ebel, Christine.

    In: Journal of Biological Chemistry, Vol. 287, 07.12.2012, p. 41963-41978.

    Publication: Research - peer-reviewJournal article

  76. Published

    The α2Na+/K+-ATPase is critical for skeletal and heart muscle function in zebrafish. / Doganli, Canan; Kjaer-Sørensen, Kasper; Knoeckel, Christopher; Beck, Hans Christian; Nyengaard, Jens Randel; Honoré, Bent; Nissen, Poul; Ribera, Angela; Oxvig, Claus; Lykke-Hartmann, Karin.

    In: Journal of Cell Science, Vol. 125, 12.2012, p. 6166-6175.

    Publication: Research - peer-reviewJournal article

  77. Published

    A bimodular mechanism of calcium control in eukaryotes. / Tidow, Henning; Poulsen, Lisbeth Rosager; Andreeva, Antonina; Knudsen, Michael; Hein, Kim L; Wiuf, Carsten; Palmgren, Michael G.; Nissen, Poul.

    In: Nature, Vol. 491, 15.11.2012, p. 468-472.

    Publication: Research - peer-reviewJournal article

  78. Published

    Flexible P-type ATPases interacting with the membrane. / Thøgersen, Lea; Nissen, Poul.

    In: Current Opinion in Structural Biology, Vol. 22, No. 4, 08.2012, p. 491-499.

    Publication: Research - peer-reviewJournal article

  79. Published

    A POTluck of peptide transporters. / Nissen, Poul.

    In: E M B O Journal, Vol. 31, No. 16, 27.07.2012, p. 3382-3383.

    Publication: Research - peer-reviewJournal article

  80. Published

    Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy. / Denmeade, Samuel R; Mhaka, Annastasiah M; Rosen, D Marc; Brennen, W Nathaniel; Dalrymple, Susan; Dach, Ingrid; Olesen, Claus; Gurel, Bora; Demarzo, Angelo M; Wilding, George; Carducci, Michael A; Dionne, Craig A; Møller, Jesper V; Nissen, Poul; Christensen, Søren Brøgger; Isaacs, John T.

    In: Science Translational Medicine, Vol. 4, No. 140, 27.06.2012, p. 140ra86.

    Publication: Research - peer-reviewJournal article

  81. Published

    Protein kinase A (PKA) phosphorylation of Na+/K+-ATPase opens intracellular C-terminal water pathway leading to third Na+-binding site in molecular dynamics simulations. / Poulsen, Hanne; Nissen, Poul; Mouritsen, Ole G.; Khandelia, Himanshu.

    In: Journal of Biological Chemistry, Vol. 287, No. 19, 04.05.2012, p. 15959-15965.

    Publication: Research - peer-reviewJournal article

  82. Published

    Purification, crystallization and preliminary crystallographic studies of a PacL homologue from Listeria monocytogenes. / Hein, Kim Langmach; Nissen, Poul; Morth, Jens Preben.

    In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online, Vol. 68, No. Part 4, 04.2012, p. 424-427.

    Publication: Research - peer-reviewJournal article

  83. Published

    Structural models of the human copper P-type ATPases ATP7A and ATP7B. / Gourdon, P.; Sitsel, Oleg; Karlsen, J.L.; Møller, L.B.; Nissen, Poul.

    In: Biological Chemistry, Vol. 393, No. 4, 01.03.2012, p. 205-216.

    Publication: Research - peer-reviewJournal article

  84. Published

    The Busiest of All Ribosomal Assistants : Elongation Factor Tu. / Kavaliauskas, Darius; Nissen, Poul; Knudsen, Charlotte R.

    In: Biochemistry, Vol. 51, No. 13, 03.2012, p. 2642-2651.

    Publication: Research - peer-reviewJournal article

  85. Published

    The inner workings of a dynamic duo. / Poulsen, Hanne; Nissen, Poul.

    In: Science, Vol. 335, No. 6067, 27.01.2012, p. 416-417.

    Publication: Research - peer-reviewJournal article

  86. Published

    CRYSTAL STRUCTURE OF A TYPE IB P-TYPE ATPASE. / Nissen, Poul (Inventor); Gourdon, Pontus (Inventor); Liu, Xiangyu (Inventor); Pedersen, Bjørn Panyella (Inventor); Mattle, Daniel (Inventor).

    Publication: ResearchPatent

  87. 2011
  88. Published

    Exploring the Na+/K+-ATPase : Src kinase complex : Understanding structure - function relationships. / Schuldt, Linda; Yatime, Laure; Fedosova, Natalya; Nissen, Poul.

    2011. Poster session presented at XXII IUCr Congress and General Assembly, Madrid, Spain.

    Publication: ResearchPoster

  89. Published
  90. Published

    Crystal structure of a copper-transporting PIB-type ATPase. / Gourdon, Pontus; Liu, Xiang-Yu; Skjørringe, Tina; Morth, J Preben; Møller, Lisbeth Birk; Pedersen, Bjørn Panyella; Nissen, Poul.

    In: Nature, Vol. 475, No. 7354, 29.06.2011, p. 59-64.

    Publication: Research - peer-reviewJournal article

  91. Published

    Crystallization and preliminary structural analysis of the it Listeria monocytogenes Ca2+-ATPase LMCA1. / Andersen, Jacob Lauwring; Gourdon, Pontus; Møller, Jesper Vuust; Morth, Jens Preben; Nissen, Poul.

    In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online, Vol. 67, No. 6, 01.06.2011, p. 718-722.

    Publication: Research - peer-reviewJournal article

  92. Published

    Distribution of Na/K-ATPase alpha 3 isoform, a sodium-potassium P-type pump associated with rapid-onset of dystonia parkinsonism (RDP) in the adult mouse brain. / Bøttger, Pernille; Tracz, Zuzanna; Heuck, Anders; Nissen, Poul; Romero-Ramos, Marina; Lykke-Hartmann, Karin.

    In: Journal of Comparative Neurology, Vol. 519, No. 2, 01.02.2011, p. 376-404.

    Publication: Research - peer-reviewJournal article

  93. Published

    A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps. / Morth, Jens Preben; Pedersen, Bjørn Panella; Buch-Pedersen, Morten Jeppe; Andersen, Jens Peter; Vilsen, Bente; Palmgren, Michael G; Nissen, Poul.

    In: Nature Reviews. Molecular Cell Biology, Vol. 12, 01.2011, p. 60-70.

    Publication: Research - peer-reviewJournal article

  94. Published

    Characterization of the Listeria monocytogenes Ca2+-pump - a SERCA-type ATPase with only one Ca2+-binding site. / Faxén, Kristina; Andersen, Jacob Lauwring; Gourdon, Pontus; Fedosova, Natalya; Morth, Jens Preben; Nissen, Poul; Møller, Jesper Vuust.

    In: Journal of Biological Chemistry, Vol. 286, 2011, p. 1609-1617.

    Publication: Research - peer-reviewJournal article

  95. Published

    Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability. / Jensen, Jan K; Thompson, Lawrence C; Bucci, Joel C; Nissen, Poul; Gettins, Peter G W; Peterson, Cynthia B; Andreasen, Peter A; Morth, J Preben.

    In: Journal of Biological Chemistry, Vol. 286, No. 34, 2011, p. 29709-17.

    Publication: Research - peer-reviewJournal article

  96. Published

    Crystallization and preliminary structural analysis of the Listeria monocytogenes Ca(2+)-ATPase LMCA1. / Andersen, Jacob Lauwring; Gourdon, Pontus; Møller, Jesper Vuust; Morth, Jens Preben; Nissen, Poul.

    In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online, Vol. 67, No. Pt 6, 2011, p. 718-22.

    Publication: Research - peer-reviewJournal article

  97. Published

    HiLiDe—Systematic Approach to Membrane Protein Crystallization in Lipid and Detergent. / Gourdon, Pontus; Andersen, Jacob Lauwring; Hein, Kim Langmach; Bublitz, Maike; Pedersen, Bjørn Panyella; Liu, Xiang-Yu; Yatime, Laure; Nyblom, Maria; Nielsen, Thorbjørn Terndrup; Olesen, Claus; Møller, Jesper Vuust; Nissen, Poul; Morth, Jens Preben.

    In: Crystal Growth & Design, Vol. 11, No. 6, 2011, p. 2098-2106.

    Publication: Research - peer-reviewJournal article

  98. Published
  99. Published
  100. Published

    Mutual adaptation of a membrane protein and its lipid bilayer during conformational changes. / Sonntag, Yonathan; Musgaard, Maria; Olesen, Claus; Schiøtt, Birgit; Møller, Jesper Vuust; Nissen, Poul; Thøgersen, Lea.

    In: Nature Communications, Vol. 2, 2011, p. 304.

    Publication: Research - peer-reviewJournal article

  101. Published

    P-type ATPases. / Palmgren, Michael Broberg; Nissen, Poul.

    In: Annual Review of Biophysics, Vol. 40, 2011, p. 243-66.

    Publication: Research - peer-reviewJournal article

  102. Published

    P-type ATPases at a glance. / Bublitz, Maike; Morth, J Preben; Nissen, Poul.

    In: Journal of Cell Science, Vol. 124, No. Pt 15, 2011, p. 2515-9.

    Publication: Research - peer-reviewJournal article

  103. Published

    Structural and biophysical characterisation of agrin laminin G3 domain constructs. / Tidow, Henning; Mattle, Daniel; Nissen, Poul.

    In: Protein Engineering Design and Selection (Print), Vol. 24, No. 1-2, 2011, p. 219-224.

    Publication: Research - peer-reviewJournal article

  104. Published

    Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase. / Yatime, Laure; Laursen, Mette; Morth, Jens Preben; Esmann, Mikael; Nissen, Poul; Fedosova, Natalya.

    In: Journal of Structural Biology, Vol. 174, 2011, p. 296-306.

    Publication: Research - peer-reviewJournal article

  105. Published

    Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase. / Yatime, Laure; Laursen, Mette; Morth, J Preben; Esmann, Mikael; Nissen, Poul; Fedosova, Natalya U.

    In: Journal of Structural Biology, Vol. 174, No. 2, 2011, p. 296-306.

    Publication: Research - peer-reviewJournal article

  106. Published

    Structure of the RACK1 dimer from Saccharomyces cerevisiae. / Yatime, Laure; Hein, Kim Langemach; Nilsson, Jakob; Nissen, Poul.

    In: Journal of Molecular Biology, Vol. 411, No. 2, 2011, p. 486-98.

    Publication: Research - peer-reviewJournal article

  107. Published

    Thapsigargin affinity purification of intracellular P(2A)-type Ca(2+) ATPases. / Vandecaetsbeek, I; Christensen, S.B; Liu, H; Van Veldhoven, PP; Waelkens, E; Eggermont, J; Raeymaekers, L; Møller, Jesper Vuust; Nissen, Poul; Wuytack, F; Vangheluwe, P.

    In: Biochimica et Biophysica Acta, Vol. 1813, No. 5, 2011, p. 1118-27.

    Publication: Research - peer-reviewJournal article

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