Department of Economics and Business Economics

Marianne Simonsen

Gender and injuries predict stimulant medication

Research output: Research - peer-reviewJournal article

Standard

Gender and injuries predict stimulant medication. / Dalsgaard, Søren; Leckman, James F.; Nielsen, Helena Skyt; Simonsen, Marianne.

In: Journal of Child and Adolescent Psychopharmacology, Vol. 24, No. 5, 13.05.2014, p. 253-259.

Research output: Research - peer-reviewJournal article

Harvard

Dalsgaard, S, Leckman, JF, Nielsen, HS & Simonsen, M 2014, 'Gender and injuries predict stimulant medication' Journal of Child and Adolescent Psychopharmacology, vol 24, no. 5, pp. 253-259. DOI: 10.1089/cap.2013.0101

APA

Dalsgaard, S., Leckman, J. F., Nielsen, H. S., & Simonsen, M. (2014). Gender and injuries predict stimulant medication. Journal of Child and Adolescent Psychopharmacology, 24(5), 253-259. DOI: 10.1089/cap.2013.0101

CBE

Dalsgaard S, Leckman JF, Nielsen HS, Simonsen M. 2014. Gender and injuries predict stimulant medication. Journal of Child and Adolescent Psychopharmacology. 24(5):253-259. Available from: 10.1089/cap.2013.0101

MLA

Dalsgaard, Søren et al."Gender and injuries predict stimulant medication". Journal of Child and Adolescent Psychopharmacology. 2014, 24(5). 253-259. Available: 10.1089/cap.2013.0101

Vancouver

Dalsgaard S, Leckman JF, Nielsen HS, Simonsen M. Gender and injuries predict stimulant medication. Journal of Child and Adolescent Psychopharmacology. 2014 May 13;24(5):253-259. Available from, DOI: 10.1089/cap.2013.0101

Author

Dalsgaard, Søren ; Leckman, James F. ; Nielsen, Helena Skyt ; Simonsen, Marianne. / Gender and injuries predict stimulant medication. In: Journal of Child and Adolescent Psychopharmacology. 2014 ; Vol. 24, No. 5. pp. 253-259

Bibtex

@article{603280741b7a4b22a6b5ee88736830b4,
title = "Gender and injuries predict stimulant medication",
abstract = "Objective: The purpose of this article was to examine whether injuries in early childhood and gender predict prescriptions of stimulant medication in three groups of children: With attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and other psychiatric disorders (OPD). Methods: This was a population-based study with prospective and complete follow-up of children with ADHD (n=11,553), ASD (n=9698), and OPD (n=48,468), of whom 61%, 16%, and 3%, respectively, were treated with stimulants. For all 69,719 individual children data on psychiatric diagnoses, injuries, and drug prescriptions were obtained from national registers and merged. Results: Having sustained an injury before 5 years of age increased the likelihood of later stimulant treatment, in children with ADHD (odds ratio [OR]=1.09; 95% confidence interval [CI]=1.01-1.21), ASD (OR=1.19; 95% CI=1.02-1.40), and OPD (OR=1.24; 95% CI=1.08-1.42), with each injury increasing the likelihood by 3%, 10%, and 7%, respectively. Head injury did not increase the likelihood of later stimulant treatment. Within each of the three groups, ADHD, ASD, and OPD boys were more likely than girls to receive stimulant medication, OR=1.17 (95% CI=1.07-1.28); OR=1.71 (95% CI=1.47-2.01), and OR=2.41 (95% CI=2.16-2.71), respectively. Conclusions: To our knowledge, this is the first prospective study assessing early life predictors of later ADHD medication in children with a psychiatric disorder, taken from a national cohort with complete follow-up of all cases. We found that the number of injuries prior to diagnosis was associated with initiation of stimulant treatment in all three groups of patients. In addition, male gender predicted treatment with ADHD medications. Our results suggest that the number of injuries early in life prior to diagnosis is associated with stimulant treatment, and may serve as a proxy for the level of later severity of ADHD symptoms, as it is universally associated with pharmacological treatment for ADHD.",
keywords = "ADHD, Methylphenidate, Injuries, Medication",
author = "Søren Dalsgaard and Leckman, {James F.} and Nielsen, {Helena Skyt} and Marianne Simonsen",
note = "Campus adgang til artiklen / Campus access to the article",
year = "2014",
month = "5",
doi = "10.1089/cap.2013.0101",
volume = "24",
pages = "253--259",
journal = "Journal of Child and Adolescent Psychopharmacology",
issn = "1044-5463",
publisher = "Mary AnnLiebert, Inc. Publishers",
number = "5",

}

RIS

TY - JOUR

T1 - Gender and injuries predict stimulant medication

AU - Dalsgaard,Søren

AU - Leckman,James F.

AU - Nielsen,Helena Skyt

AU - Simonsen,Marianne

N1 - Campus adgang til artiklen / Campus access to the article

PY - 2014/5/13

Y1 - 2014/5/13

N2 - Objective: The purpose of this article was to examine whether injuries in early childhood and gender predict prescriptions of stimulant medication in three groups of children: With attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and other psychiatric disorders (OPD). Methods: This was a population-based study with prospective and complete follow-up of children with ADHD (n=11,553), ASD (n=9698), and OPD (n=48,468), of whom 61%, 16%, and 3%, respectively, were treated with stimulants. For all 69,719 individual children data on psychiatric diagnoses, injuries, and drug prescriptions were obtained from national registers and merged. Results: Having sustained an injury before 5 years of age increased the likelihood of later stimulant treatment, in children with ADHD (odds ratio [OR]=1.09; 95% confidence interval [CI]=1.01-1.21), ASD (OR=1.19; 95% CI=1.02-1.40), and OPD (OR=1.24; 95% CI=1.08-1.42), with each injury increasing the likelihood by 3%, 10%, and 7%, respectively. Head injury did not increase the likelihood of later stimulant treatment. Within each of the three groups, ADHD, ASD, and OPD boys were more likely than girls to receive stimulant medication, OR=1.17 (95% CI=1.07-1.28); OR=1.71 (95% CI=1.47-2.01), and OR=2.41 (95% CI=2.16-2.71), respectively. Conclusions: To our knowledge, this is the first prospective study assessing early life predictors of later ADHD medication in children with a psychiatric disorder, taken from a national cohort with complete follow-up of all cases. We found that the number of injuries prior to diagnosis was associated with initiation of stimulant treatment in all three groups of patients. In addition, male gender predicted treatment with ADHD medications. Our results suggest that the number of injuries early in life prior to diagnosis is associated with stimulant treatment, and may serve as a proxy for the level of later severity of ADHD symptoms, as it is universally associated with pharmacological treatment for ADHD.

AB - Objective: The purpose of this article was to examine whether injuries in early childhood and gender predict prescriptions of stimulant medication in three groups of children: With attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and other psychiatric disorders (OPD). Methods: This was a population-based study with prospective and complete follow-up of children with ADHD (n=11,553), ASD (n=9698), and OPD (n=48,468), of whom 61%, 16%, and 3%, respectively, were treated with stimulants. For all 69,719 individual children data on psychiatric diagnoses, injuries, and drug prescriptions were obtained from national registers and merged. Results: Having sustained an injury before 5 years of age increased the likelihood of later stimulant treatment, in children with ADHD (odds ratio [OR]=1.09; 95% confidence interval [CI]=1.01-1.21), ASD (OR=1.19; 95% CI=1.02-1.40), and OPD (OR=1.24; 95% CI=1.08-1.42), with each injury increasing the likelihood by 3%, 10%, and 7%, respectively. Head injury did not increase the likelihood of later stimulant treatment. Within each of the three groups, ADHD, ASD, and OPD boys were more likely than girls to receive stimulant medication, OR=1.17 (95% CI=1.07-1.28); OR=1.71 (95% CI=1.47-2.01), and OR=2.41 (95% CI=2.16-2.71), respectively. Conclusions: To our knowledge, this is the first prospective study assessing early life predictors of later ADHD medication in children with a psychiatric disorder, taken from a national cohort with complete follow-up of all cases. We found that the number of injuries prior to diagnosis was associated with initiation of stimulant treatment in all three groups of patients. In addition, male gender predicted treatment with ADHD medications. Our results suggest that the number of injuries early in life prior to diagnosis is associated with stimulant treatment, and may serve as a proxy for the level of later severity of ADHD symptoms, as it is universally associated with pharmacological treatment for ADHD.

KW - ADHD

KW - Methylphenidate

KW - Injuries

KW - Medication

U2 - 10.1089/cap.2013.0101

DO - 10.1089/cap.2013.0101

M3 - Journal article

VL - 24

SP - 253

EP - 259

JO - Journal of Child and Adolescent Psychopharmacology

T2 - Journal of Child and Adolescent Psychopharmacology

JF - Journal of Child and Adolescent Psychopharmacology

SN - 1044-5463

IS - 5

ER -