Magnus Kjærgaard

  1. 2016
  2. Published

    Single-molecule imaging of individual amyloid protein aggregates in human biofluids. / Horrocks, Mathew Harry; Lee, Steven F; Gandhi, Sonia; Magdalinou, Nadia K; Chen, Serene W; Devine, Michael J; Tosatto, Laura; Kjaergaard, Magnus; Beckwith, Joseph S; Zetterberg, Henrik; Iljina, Marija; Cremades, Nunilo; Dobson, Christopher M; Wood, Nicholas W; Klenerman, David.

    In: A C S Chemical Neuroscience, Vol. 7, No. 3, 22.01.2016, p. 399–406.

    Publication: Research - peer-reviewJournal article

  3. Published

    Engineering a prototypic P-type ATPase Listeria Monocytogenes Ca(2+)-ATPase 1 for single-molecule FRET studies. / Dyla, Mateusz; Andersen, Jacob; Kjaergaard, Magnus; Birkedal, Victoria; Terry, Daniel S.; Altman, Roger B.; Blanchard, Scott; Nissen, Poul; Knudsen, Charlotte R.

    In: Bioconjugate Chemistry, Vol. 27, No. 9, 2016, p. 2176-2187.

    Publication: Research - peer-reviewJournal article

  4. 2015
  5. Published

    A mechanistic model of tau amyloid aggregation based on direct observation of oligomers. / Shammas, Sarah L; Garcia, Gonzalo A; Kumar, Satish; Kjaergaard, Magnus; Horrocks, Mathew H; Shivji, Nadia; Mandelkow, Eva; Knowles, Tuomas P J; Mandelkow, Eckhard; Klenerman, David.

    In: Nature Communications, Vol. 6, 2015, p. 7025.

    Publication: Research - peer-reviewJournal article

  6. Published

    Can proteins be intrinsically disordered inside a membrane? / Kjærgaard, Magnus.

    In: Intrinsically Disordered Proteins, Vol. 3, No. 1, e984570, 2015, p. 1-7.

    Publication: Research - peer-reviewJournal article

  7. 2014
  8. Published

    Helical propensity in an intrinsically disordered protein accelerates ligand binding. / Iešmantavičius, Vytautas; Dogan, Jakob; Jemth, Per; Teilum, Kaare; Kjærgaard, Magnus.

    In: Angewandte Chemie (International Edition), Vol. 53, No. 6, 03.02.2014, p. 1548-51.

    Publication: Research - peer-reviewJournal article

  9. 2013
  10. Published

    Single-molecule measurements of transient biomolecular complexes through microfluidic dilution. / Horrocks, Mathew H; Rajah, Luke; Jönsson, Peter; Kjærgaard, Magnus; Vendruscolo, Michele; Knowles, Tuomas P J; Klenerman, David.

    In: Analytical Chemistry, Vol. 85, No. 14, 16.07.2013, p. 6855-9.

    Publication: Research - peer-reviewJournal article

  11. Published

    Modulation of the intrinsic helix propensity of an intrinsically disordered protein reveals long-range helix-helix interactions. / Iešmantavičius, Vytautas; Jensen, Malene Ringkjøbing; Ozenne, Valéry; Blackledge, Martin; Poulsen, Flemming Martin; Kjærgaard, Magnus.

    In: American Chemical Society. Journal, Vol. 135, No. 27, 10.07.2013, p. 10155-63.

    Publication: Research - peer-reviewJournal article

  12. Published

    A folded excited state of ligand-free nuclear coactivator binding domain (NCBD) underlies plasticity in ligand recognition. / Kjærgaard, Magnus; Andersen, Lisbeth; Nielsen, Lau Dalby; Teilum, Kaare.

    In: Biochemistry, Vol. 52, No. 10, 12.03.2013, p. 1686-93.

    Publication: Research - peer-reviewJournal article

  13. 2012
  14. Published

    A flexible multidomain structure drives the function of the urokinase-type plasminogen activator receptor (uPAR). / Mertens, Haydyn D T; Kjærgaard, Magnus; Mysling, Simon; Gårdsvoll, Henrik; Jørgensen, Thomas J D; Svergun, Dmitri I; Ploug, Michael.

    In: Journal of Biological Chemistry, Vol. 287, No. 41, 05.10.2012, p. 34304-15.

    Publication: Research - peer-reviewJournal article

  15. Published

    Is a malleable protein necessarily highly dynamic? The hydrophobic core of the nuclear coactivator binding domain is well ordered. / Kjærgaard, Magnus; Poulsen, Flemming Martin; Teilum, Kaare.

    In: Biophysical Journal, Vol. 102, No. 7, 04.04.2012, p. 1627-35.

    Publication: Research - peer-reviewJournal article

  16. Published

    Disordered proteins studied by chemical shifts. / Kjærgaard, Magnus; Poulsen, Flemming Martin.

    In: Progress in Nuclear Magnetic Resonance Spectroscopy, Vol. 60, 01.2012, p. 42-51.

    Publication: Research - peer-reviewJournal article

  17. Published

    Analyzing temperature-induced transitions in disordered proteins by NMR spectroscopy and secondary chemical shift analyses. / Kjærgaard, Magnus; Poulsen, Flemming Martin; Kragelund, Birthe Brandt.

    In: Methods in molecular biology (Clifton, N.J.), Vol. 896, 2012, p. 249-56.

    Publication: Research - peer-reviewJournal article

  18. Published

    Temperature-induced transitions in disordered proteins probed by NMR spectroscopy. / Kjærgaard, Magnus; Poulsen, Flemming Martin; Kragelund, Birthe Brandt.

    In: Methods in molecular biology (Clifton, N.J.), Vol. 896, 2012, p. 233-47.

    Publication: Research - peer-reviewJournal article

  19. 2011
  20. Published

    Mimicry of the regulatory role of urokinase in lamellipodia formation by introduction of a non-native interdomain disulfide bond in its receptor. / Gårdsvoll, Henrik; Kjærgaard, Magnus; Jacobsen, Benedikte; Kriegbaum, Mette Camilla; Huang, Mingdong; Ploug, Michael.

    In: Journal of Biological Chemistry, Vol. 286, No. 50, 16.12.2011, p. 43515-26.

    Publication: Research - peer-reviewJournal article

  21. Published

    The interplay between transient α-helix formation and side chain rotamer distributions in disordered proteins probed by methyl chemical shifts. / Kjærgaard, Magnus; Iešmantavičius, Vytautas; Poulsen, Flemming Martin.

    In: Protein Science, Vol. 20, No. 12, 12.2011, p. 2023-34.

    Publication: Research - peer-reviewJournal article

  22. Published

    Sequence correction of random coil chemical shifts : correlation between neighbor correction factors and changes in the Ramachandran distribution. / Kjærgaard, Magnus; Poulsen, Flemming Martin.

    In: Journal of Biomolecular N M R, Vol. 50, No. 2, 06.2011, p. 157-65.

    Publication: Research - peer-reviewJournal article

  23. Published

    The intracellular distal tail of the Na+/H+ exchanger NHE1 is intrinsically disordered: implications for NHE1 trafficking. / Nørholm, Ann-Beth; Hendus-Altenburger, Ruth; Bjerre, Gabriel Peder; Kjærgaard, Magnus; Pedersen, Stine F; Kragelund, Birthe Brandt.

    In: Biochemistry, Vol. 50, No. 17, 03.05.2011, p. 3469-80.

    Publication: Research - peer-reviewJournal article

  24. Published

    Random coil chemical shift for intrinsically disordered proteins: effects of temperature and pH. / Kjærgaard, Magnus; Brander, Søren; Poulsen, Flemming Martin.

    In: Journal of Biomolecular N M R, Vol. 49, No. 2, 02.2011, p. 139-49.

    Publication: Research - peer-reviewJournal article

  25. Published

    The RelA nuclear localization signal folds upon binding to IκBα. / Cervantes, Carla F; Bergqvist, Simon; Kjærgaard, Magnus; Kroon, Gerard; Sue, Shih-Che; Dyson, H Jane; Komives, Elizabeth A.

    In: Journal of Molecular Biology, Vol. 405, No. 3, 21.01.2011, p. 754-64.

    Publication: Research - peer-reviewJournal article

  26. 2010
  27. Published

    Temperature-dependent structural changes in intrinsically disordered proteins: formation of alpha-helices or loss of polyproline II? / Kjærgaard, Magnus; Nørholm, Ann-Beth; Hendus-Altenburger, Ruth; Pedersen, Stine F; Poulsen, Flemming Martin; Kragelund, Birthe Brandt.

    In: Protein Science, Vol. 19, No. 8, 08.2010, p. 1555-64.

    Publication: Research - peer-reviewJournal article

  28. Published

    Conformational selection in the molten globule state of the nuclear coactivator binding domain of CBP. / Kjærgaard, Magnus; Teilum, Kaare; Poulsen, Flemming Martin.

    In: National Academy of Sciences. Proceedings, Vol. 107, No. 28, 13.07.2010, p. 12535-40.

    Publication: Research - peer-reviewJournal article

  29. 2008
  30. Published

    Rapid mass spectrometric analysis of 15N-Leu incorporation fidelity during preparation of specifically labeled NMR samples. / Truhlar, Stephanie M E; Cervantes, Carla F; Torpey, Justin W; Kjærgaard, Magnus; Komives, Elizabeth A.

    In: Protein Science, Vol. 17, No. 9, 09.2008, p. 1636-9.

    Publication: Research - peer-reviewJournal article

  31. Published

    Structure and Inhibition of the Urokinase-Type Plasminogen Activator Receptor. / Jacobsen, Benedikte; Kjærgaard, Magnus; Gårdsvoll, Henrik; Ploug, Michael.

    The Cancer Degradome. Springer, 2008.

    Publication: Research - peer-reviewBook chapter

  32. Published

    Structure and ligand interactions of the urokinase receptor (uPAR). / Kjærgaard, Magnus; Hansen, Line V; Jacobsen, Benedikte; Gardsvoll, Henrik; Ploug, Michael.

    In: Frontiers in Bioscience, Vol. 13, 2008, p. 5441-61.

    Publication: Research - peer-reviewJournal article

  33. 2007
  34. Published

    Solution structure of recombinant somatomedin B domain from vitronectin produced in Pichia pastoris. / Kjærgaard, Magnus; Gårdsvoll, Henrik; Hirschberg, Daniel; Nielbo, Steen; Mayasundari, Anand; Peterson, Cynthia B; Jansson, Anna; Jørgensen, Thomas J. D.; Poulsen, Flemming Martin; Ploug, Michael.

    In: Protein Science, Vol. 16, No. 9, 09.2007, p. 1934-45.

    Publication: Research - peer-reviewJournal article

  35. 2006
  36. Published

    Thermodynamics reveal that helix four in the NLS of NF-kappaB p65 anchors IkappaBalpha, forming a very stable complex. / Bergqvist, Simon; Croy, Carrie H; Kjærgaard, Magnus; Huxford, Tom; Ghosh, Gourisankar; Komives, Elizabeth A.

    In: Journal of Molecular Biology, Vol. 360, No. 2, 07.07.2006, p. 421-34.

    Publication: Research - peer-reviewJournal article