Leif Østergaard

Neuroplasticity in Constraint-Induced Movement Therapy

Research output: Contribution to book/anthology/report/proceedingArticle in proceedingsResearchpeer-review

  • Jakob Blicher
  • Jamie Near, Douglas Mental Health University Institute and Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC H3A 1A1, Canada; FMRIB Centre, University of Oxford, OxfordOX3 9DU, UK., Denmark
  • Erhard Næss-Schmidt
  • Leif Østergaard
  • Heidi Johansen-Berg, FMRIB Centre, Department of Clinical Neurology, University of Oxford, United KingdomCharlotte Stagg, FMRIB Centre, Department of Clinical Neurology, University of Oxford, United Kingdom
  • Jørgen Feldbæk Nielsen
  • Yi Ching Lynn Ho, Denmark
In healthy subjects, decreasing GABA facilitates motor learning[1]. Recent studies, using PET[2], TMS[3-5], and pharmacological challenges[6], have pointed indirectly to a decrease in neuronal inhibitory activity after stroke. Therefore, we hypothesize that a suppression of GABA levels post stroke might be beneficial to motor recovery during Constraint-Induced Movement Therapy (CIMT).
Original languageEnglish
Title of host publicationReplace, Repair, Restore, Relieve : Bridging Clinical and Engineering Solutions in Neurorehabilitation
EditorsWinnie Jensen, Ole Kæseler Andersen, Metin Akay
Number of pages2
Publication year2014
ISBN (print)978-3-319-08071-0
ISBN (Electronic)978-3-319-08072-7
StatePublished - 2014
EventICNR 2014 - Aalborg, Denmark
Duration: 24 Jun 201426 Jun 2014


ConferenceICNR 2014
SeriesBiosystems & Biorobotics

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