Leif Østergaard

  1. 2018
  2. Published
  3. E-pub ahead of print

    The effect of carotid artery stenting on capillary transit time heterogeneity in patients with carotid artery stenosis. / Arsava, Ethem M; Hansen, Mikkel Bo; Kaplan, Berkan; Peker, Ahmet; Gocmen, Rahsan; Arat, Anil; Oguz, Kader K; Topcuoglu, Mehmet A; Østergaard, Leif; Dalkara, Turgay.

    In: European Stroke Journal, 26.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  4. Published

    Noninvasive assessment of isocitrate dehydrogenase mutation status in cerebral gliomas by magnetic resonance spectroscopy in a clinical setting. / Tietze, Anna; Choi, Changho; Mickey, Bruce; Maher, Elizabeth A; Parm Ulhøi, Benedicte; Sangill, Ryan; Lassen-Ramshad, Yasmin; Lukacova, Slavka; Østergaard, Leif; von Oettingen, Gorm.

    In: Journal of Neurosurgery: Spine, 01.02.2018, p. 1-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  5. Published

    Disturbances in the control of capillary flow in an aged APP(swe)/PS1 Delta E9 model of Alzheimer's disease. / Gutierrez-Jimenez, Eugenio; Angleys, Hugo; Rasmussen, Peter M.; West, Mark J.; Catalini, Laura; Iversen, Nina K.; Jensen, Morten S.; Frische, Sebastian; Ostergaard, Leif.

    In: Neurobiology of Aging, Vol. 62, 02.2018, p. 82-94.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  6. Published

    Hippocampal Atrophy Following Subarachnoid Hemorrhage Correlates with Disruption of Astrocyte Morphology and Capillary Coverage by AQP4. / Anzabi, Maryam; Ardalan, Maryam; Iversen, Nina Kerting; H. Rafati, Ali; Hansen, Brian; Østergaard, Leif.

    In: Frontiers in cellular neuroscience, Vol. 12, No. 19, 2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  7. Published

    Impact of age on cardiovascular function, inflammation, and oxidative stress in experimental asphyxial cardiac arrest. / Secher, N; Østergaard, L; Tønnesen, E; Hansen, F B; Granfeldt, A.

    In: Acta Anaesthesiologica Scandinavica, Vol. 62, No. 1, 2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  8. Accepted/In press

    The effects of capillary transit time heterogeneity (CTH) on the BOLD signal. / Angleys, Hugo; Jespersen, Sune; Østergaard, Leif.

    In: Human Brain Mapping, 2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  9. Published

    The effects of hypercapnia on cortical capillary transit time heterogeneity (CTH) in anesthetized mice. / Gutiérrez-Jiménez, Eugenio; Angleys, Hugo; Rasmussen, Peter Mondrup; Mikkelsen, Irene Klærke; Mouridsen, Kim; Østergaard, Leif.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 38, No. 2, 271678X17692598, 2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  10. 2017
  11. Published
  12. Published
  13. Published

    Capillary dysfunction is associated with symptom severity and neurodegeneration in Alzheimer's disease. / Nielsen, Rune B; Egefjord, Lærke; Angleys, Hugo; Mouridsen, Kim; Gejl, Michael; Møller, Arne; Brock, Birgitte; Brændgaard, Hans; Gottrup, Hanne; Rungby, Jørgen; Eskildsen, Simon F; Østergaard, Leif.

    In: Alzheimer's & Dementia, Vol. 13, No. 10, 10.2017, p. 1143-1153.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  14. Published

    Capillary dysfunction in the development of diabetic peripheral neuropathy in animal models. / Dudele, Anete; Gutierrez, Eugenio; Iversen, Nina Kerting; Frische, Sebastian; Staehelin-Jensen, Troels; Østergaard, Leif.

    2017. 276-276 Abstract from 2017 PNS (Peripheral Nerve Society) Annual Meeting , Barcelona, Spain.

    Research output: Contribution to conferenceConference abstract for conference

  15. Published

    White matter biomarkers from fast protocols using axially symmetric diffusion kurtosis imaging. / Hansen, Brian; Khan, Ahmad R; Shemesh, Noam; Lund, Torben E; Sangill, Ryan; Eskildsen, Simon F; Østergaard, Leif; Jespersen, Sune N.

    In: NMR in Biomedicine, Vol. 30, No. 9, e3741, 09.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  16. E-pub ahead of print

    Transit time homogenization in ischemic stroke - A novel biomarker of penumbral microvascular failure? / Engedal, Thorbjørn S; Hjort, Niels; Hougaard, Kristina D; Simonsen, Claus Z; Andersen, Grethe; Mikkelsen, Irene Klærke; Boldsen, Jens K; Eskildsen, Simon F; Hansen, Mikkel B; Angleys, Hugo; Jespersen, Sune N; Pedraza, Salvador; Cho, Tae-Hee; Serena, Joaquín; Siemonsen, Susanne; Thomalla, Götz; Nighoghossian, Norbert; Fiehler, Jens; Mouridsen, Kim; Østergaard, Leif.

    In: Journal of Cerebral Blood Flow and Metabolism, 31.07.2017, p. 271678X17721666.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  17. Published

    Model-based inference from microvascular measurements : Combining experimental measurements and model predictions using a Bayesian probabilistic approach. / Rasmussen, Peter M; Smith, Amy F; Sakadžić, Sava; Boas, David A; Pries, Axel R; Secomb, Timothy W; Østergaard, Leif.

    In: Microcirculation, Vol. 24, No. 4, 05.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  18. Published
  19. Published

    Schwann cell interactions with axons and microvessels in diabetic neuropathy. / Gonçalves, Nádia P; Vægter, Christian B; Andersen, Henning; Østergaard, Leif; Calcutt, Nigel A; Jensen, Troels S.

    In: Nature Reviews. Neurology, Vol. 13, 30.03.2017, p. 135-147.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  20. Published
  21. E-pub ahead of print

    Acute reperfusion without recanalization : Serial assessment of collaterals within 6 h of using perfusion-weighted magnetic resonance imaging. / Makris, Nikolaos; Chamard, Leila; Mikkelsen, Irene K; Hermier, Marc; Derex, Laurent; Pedraza, Salvador; Thomalla, Götz; Østergaard, Leif; Baron, Jean-Claude; Nighoghossian, Norbert; Berthezène, Yves; Cho, Tae-Hee.

    In: Journal of Cerebral Blood Flow and Metabolism, 01.01.2017, p. 271678X17744716.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  22. Published

    Cortical spreading depolarizations in the postresuscitation period in a cardiac arrest male rat model. / Hansen, Frederik Boe; Secher, Niels; Jensen, Morten Skovgaard; Østergaard, Leif; Tønnesen, Else Kirstine; Granfeldt, Asger.

    In: Journal of Neuroscience Research, Vol. 95, No. 10, 2017, p. 2040-2050.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  23. Published

    Increased cortical capillary transit time heterogeneity in Alzheimer’s disease: a DSC-MRI perfusion study. / Eskildsen, Simon F.; Gyldensted, Louise; Nagenthiraja, Kartheeban; Nielsen, Rune B.; Hansen, Mikkel Bo; Dalby, Rikke B.; Frandsen, Jesper; Rodell, Anders; Gyldensted, Carsten; Jespersen, Sune Nørhøj; Lund, Torben E.; Mouridsen, Kim; Brændgaard, Hans; Østergaard, Leif.

    In: Neurobiology of Aging, Vol. 50, 2017, p. 107-118.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  24. Published

    The effect of congenital heart disease on cerebral function and comorbidity in adulthood. / Arlander, Benjamin Asschenfeldt; Heiberg, Johan; Østergaard, Leif; Ringgaard, Steffen; Hjortdal, Vibeke E.

    2017. Poster session presented at 27th Annual Meeting, Scandinavian Society for Research in Cardiothoracic Surgery, Geilo, Norway.

    Research output: Contribution to conferencePoster

  25. Published

    White Matter Biomarkers from Fast Protocols Using Axially Symmetric Diffusion Kurtosis Imaging. / Hansen, Brian; Khan, Ahmad Raza; Shemesh, Noam; Lund, Torben Ellegaard; Sangill, Ryan; Østergaard, Leif; Jespersen, Sune Nørhøj.

    Proceedings of ISMRM 25th Annual Meeting. 2017. p. 1742.

    Research output: Contribution to book/anthology/report/proceedingConference abstract in proceedings

  26. 2016
  27. Published

    Effect of electrical forepaw stimulation on capillary transit-time heterogeneity (CTH). / Gutiérrez-Jiménez, Eugenio; Cai, Changsi; Mikkelsen, Irene Klærke; Rasmussen, Peter Mondrup; Angleys, Hugo; Merrild, Mads; Mouridsen, Kim; Jespersen, Sune Nørhøj; Lee, Jonghwan; Iversen, Nina Kerting; Sakadzic, Sava; Østergaard, Leif.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 36, No. 12, 01.12.2016, p. 2072-2086.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  28. E-pub ahead of print

    Reliable estimation of microvascular flow patterns in patients with disrupted blood–brain barrier using dynamic susceptibility contrast MRI. / Hansen, Mikkel Bo; Tietze, Anna; kalpathy-Cramer, jayashree; Gerstner, Elizabeth; Batchelor, Tracy T.; Østergaard, Leif; Mouridsen, Kim.

    In: Journal of Magnetic Resonance Imaging, 30.11.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  29. Accepted/In press

    Non-invasive assessment of Isocitrate dehydrogenase (IDH) mutational status in cerebral gliomas by Magnetic Resonance Spectroscopy in a clinical setting. / Tietze, Anna; Choi, Changho; Mickey, Bruce; Maher, Elizabeth; Ulhøi, Benedicte Parm; Sangill, Ryan; Lassen, Yasmin Alexandra; Lukácová, Slávka; Østergaard, Leif; Oettingen, Gorm von.

    In: Journal of Neurosurgery, 13.10.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  30. Published

    White matter biomarkers from fast protocols using axially symmetric diffusion kurtosis imaging. / Hansen, Brian; Khan, Ahmad R.; Shemesh, Noam; Lund, Torben E.; Sangill, Ryan; Østergaard, Leif; Jespersen, Sune N.

    In: arXiv preprint, 10.10.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  31. Published

    The effects of capillary transit time heterogeneity (CTH) on the cerebral uptake of glucose and glucose analogs: Application to FDG and comparison to oxygen uptake. / Angleys, Hugo; Jespersen, Sune; Østergaard, Leif.

    In: Frontiers in Computational Neuroscience, Vol. 10, 103, 15.09.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  32. Published

    Capillary dysfunction in Alzheimer’s disease correlates with cognitive decline. / Eskildsen, Simon Fristed; Gyldensted, Louise; Nagenthiraja, Kartheeban; Hansen, Mikkel Bo; Dalby, Rikke Beese; Frandsen, Jesper; Rodell, Anders; Gyldensted, Carsten; Jespersen, Sune Nørhøj; Mouridsen, Kim; Brændgaard, Hans; Østergaard, Leif.

    2016. Abstract from 10th FENS FORUM of Neuroscience 2016, København, Denmark.

    Research output: Contribution to conferenceConference abstract for conference

  33. Published

    Perfusion and pH MRI in familial hemiplegic migraine with prolonged aura. / Blicher, Jakob Udby; Tietze, Anna; Donahue, Manus J; Smith, Seth A; Østergaard, Leif.

    In: Cephalalgia, Vol. 36, No. 3, 01.03.2016, p. 279-83.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  34. Published

    Does b1000-b0 Mismatch Challenge Diffusion-Weighted Imaging-Fluid Attenuated Inversion Recovery Mismatch in Stroke? / Geraldo, Ana Filipa; Berner, Lise-Prune; Haesebaert, Julie; Chabrol, Aurélie; Cho, Tae-Hee; Derex, Laurent; Hermier, Marc; Louis-Tisserand, Guy; Chamard, Leila; Klaerke Mikkelsen, Irene; Ribe, Lars; Østergaard, Leif; Hjort, Niels; Pedraza, Salvador; Thomalla, Götz; Baron, Jean-Claude; Nighoghossian, Norbert; Berthèzene, Yves.

    In: Stroke; a journal of cerebral circulation, 03.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  35. Published

    MRI Assessment of Ischemic Lesion Evolution within White and Gray Matter. / Berner, Lise-Prune; Cho, Tae-Hee; Haesebaert, Julie; Bouvier, Julien; Wiart, Marlène; Hjort, Niels; Klærke Mikkelsen, Irene; Derex, Laurent; Thomalla, Götz; Pedraza, Salvador; Østergaard, Leif; Baron, Jean-Claude; Nighoghossian, Norbert; Berthezène, Yves.

    In: Cerebrovascular Diseases, Vol. 41, No. 5-6, 12.02.2016, p. 291-297.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  36. E-pub ahead of print

    Assessment of tumor oxygenation and its impact on treatment response in bevacizumab-treated recurrent glioblastoma. / Bonekamp, David; Mouridsen, Kim; Radbruch, Alexander; Kurz, Felix T; Eidel, Oliver; Wick, Antje; Schlemmer, Heinz-Peter; Wick, Wolfgang; Bendszus, Martin; Østergaard, Leif; Kickingereder, Philipp.

    In: Journal of Cerebral Blood Flow and Metabolism, 09.02.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  37. Published

    Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline. / Østergaard, Leif; Engedal, Thorbjørn Søndergaard; Moreton, Fiona ; Hansen, Mikkel Bo; Wardlaw, Joanna M.; Dalkara, Turgay; Markus, Hugh S; Muir, Keith W.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 36, No. 2, 01.02.2016, p. 302-25.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  38. Published

    Automated Estimation of Salvageable Tissue : Comparison with Expert Readers. / Hansen, Mikkel Bo; Nagenthiraja, Kartheeban; Ribe, Lars Riisgaard; Hougaard, Kristina Dupont; Østergaard, Leif; Mouridsen, Kim.

    In: Journal of Magnetic Resonance Imaging, Vol. 43, No. 1, 01.2016, p. 220-228.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  39. Published

    Capillary Transit Time Heterogeneity Is Associated with Modified Rankin Scale Score at Discharge in Patients with Bilateral High Grade Internal Carotid Artery Stenosis. / Mundiyanapurath, Sibu; Ringleb, Peter Arthur; Diatschuk, Sascha; Hansen, Mikkel Bo; Mouridsen, Kim; Østergaard, Leif; Wick, Wolfgang; Bendszus, Martin; Radbruch, Alexander.

    In: PloS one, Vol. 11, No. 6, 2016, p. e0158148.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  40. Published

    Comparing anesthesia with isoflurane and fentanyl/fluanisone/midazolam in a rat model of cardiac arrest. / Secher, Niels; Malte, Christian Lind; Tønnesen, Else; Østergaard, Leif; Granfeldt, Asger.

    In: Journal of Applied Physiology, 2016, p. jap.00998.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  41. Published

    Disruption of microvascular flow-patterns in Alzheimer's disease correlates with neurodegeneration and cognitive decline. / Nielsen, Rune Bæksager; Egefjord, Lærke; Eskildsen, Simon Fristed; Møller, Arne; Brændgaard, Hans; Jensen, Michael Gejl; Brock, Birgitte; Rungby, Jørgen; Østergaard, Leif.

    2016. Abstract from 10th FENS Forum of Neuroscience 2016, .

    Research output: Contribution to conferenceConference abstract for conference

  42. Published

    Reduced cerebral cortical thickness in Non-cirrhotic patients with hepatitis C. / Hjerrild, Simon; Renvillard, Signe Groth; Leutscher, Peter; Sørensen, Leif Hougaard; Østergaard, Leif; Eskildsen, Simon Fristed; Videbech, Poul.

    In: Metabolic Brain Disease, Vol. 31, No. 2, 2016, p. 311-319.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  43. Published

    Sequential MR Assessment of the Susceptibility Vessel Sign and Arterial Occlusion in Acute Stroke. / Ritzenthaler, Thomas; Lacalm, Audrey; Cho, Tae-Hee; Maucort-Boulch, Delphine; Klaerke Mikkelsen, Irene; Ribe, Lars; Østergaard, Leif; Hjort, Niels; Fiehler, Jens; Pedraza, Salvador; Louis Tisserand, Guy; Baron, Jean-Claude; Berthezene, Yves; Nighoghossian, Norbert.

    In: Journal of Neuroimaging, Vol. 26, No. 3, 2016, p. 355-359.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  44. 2015
  45. Published

    Early Blood Brain Barrier Changes in Acute Ischemic Stroke : A Sequential MRI Study. / Giraud, Marc; Cho, Tae-Hee; Nighoghossian, Norbert; Maucort-Boulch, Delphine; Deiana, Gianluca; Østergaard, Leif; Baron, Jean-Claude; Fiehler, Jens; Pedraza, Salvador; Derex, Laurent; Berthezène, Yves.

    In: Journal of Neuroimaging, Vol. 25, No. 6, 02.12.2015, p. 959-63.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  46. Published

    Cortical Spreading Depolarizations after Cardiac Arrest in an Asphyxial Rat Model. / Hansen, Frederik Boe; Secher, Niels; Jensen, Morten Skovgaard; Østergaard, Leif; Tønnesen, Else Kirstine; Granfeldt, Asger.

    2015. Poster session presented at American Heart Association Scientific Sessions, Orlando, United States.

    Research output: Contribution to conferencePoster

  47. Published

    Evaluation of Early Reperfusion Criteria in Acute Ischemic Stroke. / Ozenne, Brice; Cho, Tae-Hee; Mikkelsen, Irene Klaerke; Hermier, Marc; Ribe, Lars; Thomalla, Götz; Pedraza, Salvador; Baron, Jean-Claude; Roy, Pascal; Berthezène, Yves; Nighoghossian, Norbert; Østergaard, Leif; Maucort-Boulch, Delphine.

    In: Journal of Neuroimaging, Vol. 25, No. 6, 01.11.2015, p. 951-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  48. Published

    Microcirculatory dysfunction and tissue oxygenation in critical illness. / Østergaard, Leif; Granfeldt, A; Secher, N; Tietze, A; Iversen, N K; Jensen, Morten Skovgaard; Andersen, Kristian Kjær; Nagenthiraja, K; Gutiérrez-Lizardi, P; Mouridsen, K; Jespersen, S N; Tønnesen, E K.

    In: Acta Anaesthesiologica Scandinavica, Vol. 59, No. 10, 01.11.2015, p. 1246-59.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  49. Published

    The Impact of Age on Coronary Perfusion, Cardiac Function and Inflammation in a Rat Model of Ashpyxial Cardiac Arrest. / Secher, Niels; Østergaard, Leif; Tønnesen, Else Kirstine; Granfeldt, Asger.

    2015. Poster session presented at American Heart Association Scientific Sessions 2015, Orlando, Florida, Denmark.

    Research output: Contribution to conferencePoster

  50. Published

    Hjernen. / Østergaard, Leif.

    Aarhus : Aarhus Universitetsforlag, 2015. 59 p.

    Research output: Book/anthology/dissertation/reportBook

  51. Published
  52. Published

    Preserved cerebral microcirculation after cardiac arrest in a rat model. / Secher, Niels; Østergaard, Leif; Iversen, Nina K; Lambertsen, Kate L; Clausen, Bettina H; Tønnesen, Else; Granfeldt, Asger.

    In: Microcirculation (New York, N.Y. : 1994), Vol. 66, No. 6, 01.08.2015, p. 464-74.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  53. Published

    Mean Diffusional Kurtosis in Patients with Glioma : Initial Results with a Fast Imaging Method in a Clinical Setting. / Tietze, A.; Hansen, Mikkel Bo; Østergaard, Leif; Jespersen, S. N.; Sangill, R.; Lund, T. E.; Geneser, M.; Hjelm, Mette; Hansen, Brian.

    In: American Journal of Neuroradiology, Vol. 36, No. 8, 08.2015, p. 1472-1478.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  54. Published

    Biased visualization of hypoperfused tissue by computed tomography due to short imaging duration : improved classification by image down-sampling and vascular models. / Mikkelsen, Irene Klærke; Jones, P Simon; Ribe, Lars Riisgaard; Alawneh, Josef; Puig, Josep; Bekke, Susanne Lise; Tietze, Anna; Gillard, Jonathan H; Warburton, Elisabeth A; Pedraza, Salva; Baron, Jean-Claude; Østergaard, Leif; Mouridsen, Kim.

    In: European Radiology, Vol. 25, No. 7, 01.07.2015, p. 2080-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

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