Leif Østergaard

  1. Published
  2. Published
  3. E-pub ahead of print
  4. Published
  5. Published

    Capillary dysfunction in the development of diabetic peripheral neuropathy in animal models. / Dudele, Anete; Gutierrez, Eugenio; Iversen, Nina Kerting; Frische, Sebastian; Staehelin-Jensen, Troels; Østergaard, Leif.

    2017. 276-276 Abstract from 2017 PNS (Peripheral Nerve Society) Annual Meeting , Barcelona, Spain.

    Research output: ResearchConference abstract for conference

  6. E-pub ahead of print

    Transit time homogenization in ischemic stroke - A novel biomarker of penumbral microvascular failure? / Engedal, Thorbjørn S; Hjort, Niels; Hougaard, Kristina D; Simonsen, Claus Z; Andersen, Grethe; Mikkelsen, Irene Klærke; Boldsen, Jens K; Eskildsen, Simon F; Hansen, Mikkel B; Angleys, Hugo; Jespersen, Sune N; Pedraza, Salvador; Cho, Tae-Hee; Serena, Joaquín; Siemonsen, Susanne; Thomalla, Götz; Nighoghossian, Norbert; Fiehler, Jens; Mouridsen, Kim; Østergaard, Leif.

    In: Journal of Cerebral Blood Flow and Metabolism, 31.07.2017, p. 271678X17721666.

    Research output: Research - peer-reviewJournal article

  7. E-pub ahead of print
  8. Published

    Model-based inference from microvascular measurements : Combining experimental measurements and model predictions using a Bayesian probabilistic approach. / Rasmussen, Peter M; Smith, Amy F; Sakadžić, Sava; Boas, David A; Pries, Axel R; Secomb, Timothy W; Østergaard, Leif.

    In: Microcirculation (New York, N.Y. : 1994), Vol. 24, No. 4, 05.2017.

    Research output: Research - peer-reviewJournal article

  9. Published

    Schwann cell interactions with axons and microvessels in diabetic neuropathy. / Gonçalves, Nádia P; Vægter, Christian B; Andersen, Henning; Østergaard, Leif; Calcutt, Nigel A; Jensen, Troels S.

    In: Nature Reviews. Neurology, Vol. 13, 30.03.2017, p. 135-147.

    Research output: Research - peer-reviewJournal article

  10. E-pub ahead of print

    Noninvasive assessment of isocitrate dehydrogenase mutation status in cerebral gliomas by magnetic resonance spectroscopy in a clinical setting. / Tietze, Anna; Choi, Changho; Mickey, Bruce; Maher, Elizabeth A; Parm Ulhøi, Benedicte; Sangill, Ryan; Lassen-Ramshad, Yasmin; Lukacova, Slavka; Østergaard, Leif; von Oettingen, Gorm.

    In: Journal of Neurosurgery: Spine, 03.03.2017, p. 1-8.

    Research output: Research - peer-reviewJournal article

  11. Published
  12. E-pub ahead of print
  13. Published

    The effect of congenital heart disease on cerebral function and comorbidity in adulthood. / Arlander, Benjamin Asschenfeldt; Heiberg, Johan; Østergaard, Leif; Ringgaard, Steffen; Hjortdal, Vibeke E.

    2017. Poster session presented at 27th Annual Meeting, Scandinavian Society for Research in Cardiothoracic Surgery, Geilo, Norway.

    Research output: Research - peer-reviewPoster

  14. Published
  15. Published
  16. Published

    White Matter Biomarkers from Fast Protocols Using Axially Symmetric Diffusion Kurtosis Imaging. / Hansen, Brian; Khan, Ahmad Raza; Shemesh, Noam; Lund, Torben Ellegaard; Sangill, Ryan; Østergaard, Leif; Jespersen, Sune Nørhøj.

    Proceedings of ISMRM 25th Annual Meeting. 2017. p. 1742.

    Research output: Research - peer-reviewConference abstract in proceedings

  17. Published

    Effect of electrical forepaw stimulation on capillary transit-time heterogeneity (CTH). / Gutiérrez-Jiménez, Eugenio; Cai, Changsi; Mikkelsen, Irene Klærke; Rasmussen, Peter Mondrup; Angleys, Hugo; Merrild, Mads; Mouridsen, Kim; Jespersen, Sune Nørhøj; Lee, Jonghwan; Iversen, Nina Kerting; Sakadzic, Sava; Østergaard, Leif.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 36, No. 12, 01.12.2016, p. 2072-2086.

    Research output: Research - peer-reviewJournal article

  18. E-pub ahead of print

    Reliable estimation of microvascular flow patterns in patients with disrupted blood–brain barrier using dynamic susceptibility contrast MRI. / Hansen, Mikkel Bo; Tietze, Anna; kalpathy-Cramer, jayashree; Gerstner, Elizabeth; Batchelor, Tracy T.; Østergaard, Leif; Mouridsen, Kim.

    In: Journal of Magnetic Resonance Imaging, 30.11.2016.

    Research output: Research - peer-reviewJournal article

  19. Accepted/In press

    Non-invasive assessment of Isocitrate dehydrogenase (IDH) mutational status in cerebral gliomas by Magnetic Resonance Spectroscopy in a clinical setting. / Tietze, Anna; Choi, Changho; Mickey, Bruce; Maher, Elizabeth; Ulhøi, Benedicte Parm; Sangill, Ryan; Lassen, Yasmin Alexandra; Lukácová, Slávka; Østergaard, Leif; Oettingen, Gorm von.

    In: Journal of Neurosurgery, 13.10.2016.

    Research output: Research - peer-reviewJournal article

  20. Published
  21. Published
  22. Published

    Capillary dysfunction in Alzheimer’s disease correlates with cognitive decline. / Eskildsen, Simon Fristed; Gyldensted, Louise; Nagenthiraja, Kartheeban; Hansen, Mikkel Bo; Dalby, Rikke Beese; Frandsen, Jesper; Rodell, Anders; Gyldensted, Carsten; Jespersen, Sune Nørhøj; Mouridsen, Kim; Brændgaard, Hans; Østergaard, Leif.

    2016. Abstract from 10th FENS FORUM of Neuroscience 2016, København, Denmark.

    Research output: Research - peer-reviewConference abstract for conference

  23. Published

    Perfusion and pH MRI in familial hemiplegic migraine with prolonged aura. / Blicher, Jakob Udby; Tietze, Anna; Donahue, Manus J; Smith, Seth A; Østergaard, Leif.

    In: Cephalalgia, Vol. 36, No. 3, 01.03.2016, p. 279-83.

    Research output: Research - peer-reviewJournal article

  24. Published

    Does b1000-b0 Mismatch Challenge Diffusion-Weighted Imaging-Fluid Attenuated Inversion Recovery Mismatch in Stroke? / Geraldo, Ana Filipa; Berner, Lise-Prune; Haesebaert, Julie; Chabrol, Aurélie; Cho, Tae-Hee; Derex, Laurent; Hermier, Marc; Louis-Tisserand, Guy; Chamard, Leila; Klaerke Mikkelsen, Irene; Ribe, Lars; Østergaard, Leif; Hjort, Niels; Pedraza, Salvador; Thomalla, Götz; Baron, Jean-Claude; Nighoghossian, Norbert; Berthèzene, Yves.

    In: Stroke; a journal of cerebral circulation, 03.2016.

    Research output: Research - peer-reviewJournal article

  25. Published

    MRI Assessment of Ischemic Lesion Evolution within White and Gray Matter. / Berner, Lise-Prune; Cho, Tae-Hee; Haesebaert, Julie; Bouvier, Julien; Wiart, Marlène; Hjort, Niels; Klærke Mikkelsen, Irene; Derex, Laurent; Thomalla, Götz; Pedraza, Salvador; Østergaard, Leif; Baron, Jean-Claude; Nighoghossian, Norbert; Berthezène, Yves.

    In: Cerebrovascular Diseases, Vol. 41, No. 5-6, 12.02.2016, p. 291-297.

    Research output: Research - peer-reviewJournal article

  26. E-pub ahead of print

    Assessment of tumor oxygenation and its impact on treatment response in bevacizumab-treated recurrent glioblastoma. / Bonekamp, David; Mouridsen, Kim; Radbruch, Alexander; Kurz, Felix T; Eidel, Oliver; Wick, Antje; Schlemmer, Heinz-Peter; Wick, Wolfgang; Bendszus, Martin; Østergaard, Leif; Kickingereder, Philipp.

    In: Journal of Cerebral Blood Flow and Metabolism, 09.02.2016.

    Research output: Research - peer-reviewJournal article

  27. Published

    Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline. / Østergaard, Leif; Engedal, Thorbjørn Søndergaard; Moreton, Fiona ; Hansen, Mikkel Bo; Wardlaw, Joanna M.; Dalkara, Turgay; Markus, Hugh S; Muir, Keith W.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 36, No. 2, 01.02.2016, p. 302-25.

    Research output: Research - peer-reviewJournal article

  28. Published

    Automated Estimation of Salvageable Tissue : Comparison with Expert Readers. / Hansen, Mikkel Bo; Nagenthiraja, Kartheeban; Ribe, Lars Riisgaard; Hougaard, Kristina Dupont; Østergaard, Leif; Mouridsen, Kim.

    In: Journal of Magnetic Resonance Imaging, Vol. 43, No. 1, 01.2016, p. 220-228.

    Research output: Research - peer-reviewJournal article

  29. Published

    Reduced cerebral cortical thickness in Non-cirrhotic patients with hepatitis C. / Hjerrild, Simon; Renvillard, Signe Groth; Leutscher, Peter; Sørensen, Leif Hougaard; Østergaard, Leif; Eskildsen, Simon Fristed; Videbech, Poul.

    In: Metabolic Brain Disease, Vol. 31, No. 2, 2016, p. 311-319.

    Research output: Research - peer-reviewJournal article

  30. Published

    Capillary Transit Time Heterogeneity Is Associated with Modified Rankin Scale Score at Discharge in Patients with Bilateral High Grade Internal Carotid Artery Stenosis. / Mundiyanapurath, Sibu; Ringleb, Peter Arthur; Diatschuk, Sascha; Hansen, Mikkel Bo; Mouridsen, Kim; Østergaard, Leif; Wick, Wolfgang; Bendszus, Martin; Radbruch, Alexander.

    In: PloS one, Vol. 11, No. 6, 2016, p. e0158148.

    Research output: Research - peer-reviewJournal article

  31. Published

    Disruption of microvascular flow-patterns in Alzheimer's disease correlates with neurodegeneration and cognitive decline. / Nielsen, Rune Bæksager; Egefjord, Lærke; Eskildsen, Simon Fristed; Møller, Arne; Brændgaard, Hans; Jensen, Michael Gejl; Brock, Birgitte; Rungby, Jørgen; Østergaard, Leif.

    2016. Abstract from 10th FENS Forum of Neuroscience 2016, .

    Research output: Research - peer-reviewConference abstract for conference

  32. Published

    Sequential MR Assessment of the Susceptibility Vessel Sign and Arterial Occlusion in Acute Stroke. / Ritzenthaler, Thomas; Lacalm, Audrey; Cho, Tae-Hee; Maucort-Boulch, Delphine; Klaerke Mikkelsen, Irene; Ribe, Lars; Østergaard, Leif; Hjort, Niels; Fiehler, Jens; Pedraza, Salvador; Louis Tisserand, Guy; Baron, Jean-Claude; Berthezene, Yves; Nighoghossian, Norbert.

    In: Journal of Neuroimaging, Vol. 26, No. 3, 2016, p. 355-359.

    Research output: Research - peer-reviewJournal article

  33. Published

    Comparing anesthesia with isoflurane and fentanyl/fluanisone/midazolam in a rat model of cardiac arrest. / Secher, Niels; Malte, Christian Lind; Tønnesen, Else; Østergaard, Leif; Granfeldt, Asger.

    In: Journal of Applied Physiology, 2016, p. jap.00998.2015.

    Research output: Research - peer-reviewJournal article

  34. Published

    Early Blood Brain Barrier Changes in Acute Ischemic Stroke : A Sequential MRI Study. / Giraud, Marc; Cho, Tae-Hee; Nighoghossian, Norbert; Maucort-Boulch, Delphine; Deiana, Gianluca; Østergaard, Leif; Baron, Jean-Claude; Fiehler, Jens; Pedraza, Salvador; Derex, Laurent; Berthezène, Yves.

    In: Journal of Neuroimaging, Vol. 25, No. 6, 02.12.2015, p. 959-63.

    Research output: Research - peer-reviewJournal article

  35. Published

    Cortical Spreading Depolarizations after Cardiac Arrest in an Asphyxial Rat Model. / Hansen, Frederik Boe; Secher, Niels; Jensen, Morten Skovgaard; Østergaard, Leif; Tønnesen, Else Kirstine; Granfeldt, Asger.

    2015. Poster session presented at American Heart Association Scientific Sessions, Orlando, United States.

    Research output: Research - peer-reviewPoster

  36. Published

    Evaluation of Early Reperfusion Criteria in Acute Ischemic Stroke. / Ozenne, Brice; Cho, Tae-Hee; Mikkelsen, Irene Klaerke; Hermier, Marc; Ribe, Lars; Thomalla, Götz; Pedraza, Salvador; Baron, Jean-Claude; Roy, Pascal; Berthezène, Yves; Nighoghossian, Norbert; Østergaard, Leif; Maucort-Boulch, Delphine.

    In: Journal of Neuroimaging, Vol. 25, No. 6, 01.11.2015, p. 951-8.

    Research output: Research - peer-reviewJournal article

  37. Published

    Microcirculatory dysfunction and tissue oxygenation in critical illness. / Østergaard, Leif; Granfeldt, A; Secher, N; Tietze, A; Iversen, N K; Jensen, Morten Skovgaard; Andersen, Kristian Kjær; Nagenthiraja, K; Gutiérrez-Lizardi, P; Mouridsen, K; Jespersen, S N; Tønnesen, E K.

    In: Acta Anaesthesiologica Scandinavica, Vol. 59, No. 10, 01.11.2015, p. 1246-59.

    Research output: Research - peer-reviewJournal article

  38. Published

    The Impact of Age on Coronary Perfusion, Cardiac Function and Inflammation in a Rat Model of Ashpyxial Cardiac Arrest. / Secher, Niels; Østergaard, Leif; Tønnesen, Else Kirstine; Granfeldt, Asger.

    2015. Poster session presented at American Heart Association Scientific Sessions 2015, Orlando, Florida, Denmark.

    Research output: Research - peer-reviewPoster

  39. Published

    Hjernen. / Østergaard, Leif.

    Aarhus : Aarhus Universitetsforlag, 2015. 59 p.

    Research output: CommunicationBook

  40. Published
  41. Published

    Preserved cerebral microcirculation after cardiac arrest in a rat model. / Secher, Niels; Østergaard, Leif; Iversen, Nina K; Lambertsen, Kate L; Clausen, Bettina H; Tønnesen, Else; Granfeldt, Asger.

    In: Microcirculation (New York, N.Y. : 1994), Vol. 66, No. 6, 01.08.2015, p. 464-74.

    Research output: Research - peer-reviewJournal article

  42. Published
  43. Published

    Biased visualization of hypoperfused tissue by computed tomography due to short imaging duration : improved classification by image down-sampling and vascular models. / Mikkelsen, Irene Klærke; Jones, P Simon; Ribe, Lars Riisgaard; Alawneh, Josef; Puig, Josep; Bekke, Susanne Lise; Tietze, Anna; Gillard, Jonathan H; Warburton, Elisabeth A; Pedraza, Salva; Baron, Jean-Claude; Østergaard, Leif; Mouridsen, Kim.

    In: European Radiology, Vol. 25, No. 7, 01.07.2015, p. 2080-8.

    Research output: Research - peer-reviewJournal article

  44. Published

    Spatially regularized mixture model for lesion segmentation with application to stroke patients. / Ozenne, Brice; Subtil, Fabien; Østergaard, Leif; Maucort-Boulch, Delphine.

    In: Biostatistics, Vol. 16, No. 3, 01.07.2015, p. 580-95.

    Research output: Research - peer-reviewJournal article

  45. Published

    Cortical capillary dysfunction in patients suspected of Alzheimer’s disease. / Eskildsen, Simon Fristed; Gyldensted, Louise; Nagenthiraja, Kartheeban; Hansen, Mikkel Bo; Dalby, Rikke Beese; Frandsen, Jesper; Rodell, Anders; Gyldensted, Carsten; Jespersen, Sune Nørhøj; Mouridsen, Kim; Brændgaard, Hans; Østergaard, Leif.

    2015. Abstract from The Alzheimer's Association International Conference 2015, Washington D.C., United States.

    Research output: Research - peer-reviewConference abstract for conference

  46. Published

    Reperfusion Within 6 Hours Outperforms Recanalization in Predicting Penumbra Salvage, Lesion Growth, Final Infarct, and Clinical Outcome. / Cho, Tae-Hee; Nighoghossian, Norbert; Mikkelsen, Irene Klærke; Derex, Laurent; Hermier, Marc; Pedraza, Salvador; Fiehler, Jens; Østergaard, Leif; Berthezène, Yves; Baron, Jean-Claude.

    In: Stroke; a journal of cerebral circulation, Vol. 46, No. 6, 06.2015, p. 1582-1589.

    Research output: Research - peer-reviewJournal article

  47. Published
  48. Published

    The effects of capillary transit time heterogeneity (CTH) on brain oxygenation. / Angleys, Hugo; Østergaard, Leif; Jespersen, Sune N.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 35, No. 5, 05.2015, p. 806-17.

    Research output: Research - peer-reviewJournal article

  49. Published

    Neurovascular coupling during cortical spreading depolarization and -depression. / Østergaard, Leif; Dreier, Jens Peter; Hadjikhani, Nouchine; Jespersen, Sune Nørhøj; Dirnagl, Ulrich; Dalkara, Turgay.

    In: Stroke; a journal of cerebral circulation, Vol. 46, No. 5, 05.2015, p. 1392-401.

    Research output: Research - peer-reviewJournal article

  50. Published

    Validity of shape as a predictive biomarker of final infarct volume in acute ischemic stroke. / Frindel, Carole; Rouanet, Anaïs; Giacalone, Mathilde; Cho, Tae-Hee; Østergaard, Leif; Fiehler, Jens; Pedraza, Salvador; Baron, Jean-Claude; Wiart, Marlène; Berthezène, Yves; Nighoghossian, Norbert; Rousseau, David.

    In: Stroke; a journal of cerebral circulation, Vol. 46, No. 4, 04.2015, p. 976-81.

    Research output: Research - peer-reviewJournal article

  51. Published

    GABA Levels Are Decreased After Stroke and GABA Changes During Rehabilitation Correlate With Motor Improvement. / Blicher, Jakob; Near, Jamie; Næss-Schmidt, Erhard; Stagg, Charlotte J; Johansen-Berg, Heidi; Nielsen, Jørgen Feldbæk; Østergaard, Leif; Ho, Yi Ching Lynn.

    In: Neurorehabilitation and Neural Repair, Vol. 29, No. 3, 2015, p. 278-86.

    Research output: Research - peer-reviewJournal article

  52. Published

    Making sense: Dopamine activates conscious self-monitoring through medial prefrontal cortex. / Joensson, Morten; Rømer Thomsen, Kristine; Andersen, Lau M.; Gross, Joachim; Mouridsen, Kim; Sandberg, Kristian; Østergaard, Leif; Lou, Hans Olav Christensen.

    In: Human Brain Mapping, Vol. 36, No. 5, 2015, p. 1866-77.

    Research output: Research - peer-reviewJournal article

  53. Published

    The effects of transit time heterogeneity on brain oxygenation during rest and functional activation. / Rasmussen, Peter Mondrup; Jespersen, Sune N; Ostergaard, Leif.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 35, No. 3, 2015, p. 432-42.

    Research output: Research - peer-reviewJournal article

  54. Published
  55. Published
  56. Published

    A multicenter, randomized, double-blind, placebo-controlled trial to test efficacy and safety of magnetic resonance imaging-based thrombolysis in wake-up stroke (WAKE-UP). / Thomalla, Götz; Fiebach, Jochen B; Østergaard, Leif; Pedraza, Salvador; Thijs, Vincent; Nighoghossian, Norbert; Roy, Pascal; Muir, Keith W; Ebinger, Martin; Cheng, Bastian; Galinovic, Ivana; Cho, Tae-Hee; Puig, Josep; Boutitie, Florent; Simonsen, Claus Z; Endres, Matthias; Fiehler, Jens; Gerloff, Christian; WAKE-UP investigators.

    In: International Journal of Stroke, Vol. 9, No. 6, 08.2014, p. 829-36.

    Research output: Research - peer-reviewJournal article

  57. Published
  58. Published

    Perfusion Magnetic Resonance Imaging : A Comprehensive Update on Principles and Technique. / Jahng, Geon-Ho; Li, Ka-Loh; Østergaard, Leif; Calamante, Fernando.

    In: Korean Journal of Radiology, Vol. 15, No. 5, 15.07.2014, p. 554-577.

    Research output: Research - peer-reviewJournal article

  59. Published
  60. Published

    Influence of stroke infarct location on functional outcome measured by the modified rankin scale. / Cheng, Bastian; Forkert, Nils Daniel; Zavaglia, Melissa; Hilgetag, Claus C; Golsari, Amir; Siemonsen, Susanne; Fiehler, Jens; Pedraza, Salvador; Puig, Josep; Cho, Tae-Hee; Alawneh, Josef; Baron, Jean-Claude; Østergaard, Leif; Gerloff, Christian; Thomalla, Götz.

    In: Stroke; a journal of cerebral circulation, Vol. 45, No. 6, 06.2014, p. 1695-702.

    Research output: Research - peer-reviewJournal article

  61. Published

    The role of capillary transit time heterogeneity in myocardial oxygenation and ischemic heart disease. / Østergaard, Leif; Kristiansen, Steen Buus; Angleys, Hugo; Frøkiær, Jørgen; Michael Hasenkam, J; Jespersen, Sune Nørhøj; Bøtker, Hans Erik.

    In: Basic Research in Cardiology, Vol. 109, No. 3, 409, 18.04.2014.

    Research output: Research - peer-reviewJournal article

  62. Published

    Assessment of ischemic penumbra in patients with hyperacute stroke using amide proton transfer (APT) chemical exchange saturation transfer (CEST) MRI. / Tietze, Anna; Blicher, Jakob; Mikkelsen, Irene Klærke; Østergaard, Leif; Strother, Megan K; Smith, Seth A; Donahue, Manus J.

    In: N M R in Biomedicine (Online), Vol. 27, No. 2, 02.2014, p. 163-174.

    Research output: Research - peer-reviewJournal article

  63. Published

    Remote Ischemic Perconditioning as an Adjunct Therapy to Thrombolysis in Patients With Acute Ischemic Stroke : A Randomized Trial. / Hougaard, Kristina Dupont; Hjort, Niels; Zeidler, Dora; Sørensen, Leif; Nørgaard, Anne; Hansen, Troels Martin; Weitzel, Paul von; Simonsen, Claus Z; Damgaard, Dorte Winther; Gottrup, Hanne; Svendsen, Kristina; Rasmussen, Peter Vestergaard; Ribe, Lars R; Mikkelsen, Irene K; Nagenthiraja, Kartheeban; Cho, Tae-Hee; Redington, Andrew N; Bøtker, Hans Erik; Østergaard, Leif; Mouridsen, Kim; Andersen, Grethe.

    In: Stroke; a journal of cerebral circulation, Vol. 45, No. 1, 03.01.2014, p. 159-67.

    Research output: Research - peer-reviewJournal article

  64. Published

    Blood pressure reduction does not reduce perihematoma oxygenation : a CT perfusion study. / Kate, Mahesh P; Hansen, Mikkel B; Mouridsen, Kim; Østergaard, Leif; Choi, Victor; Gould, Bronwen E; McCourt, Rebecca; Hill, Michael D; Demchuk, Andrew M; Coutts, Shelagh B; Dowlatshahi, Dariush; Emery, Derek J; Buck, Brian H; Butcher, Kenneth S.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 34, No. 1, 03.01.2014, p. 81-86.

    Research output: Research - peer-reviewJournal article

  65. Published

    Neuroplasticity in Constraint-Induced Movement Therapy. / Blicher, Jakob; Near, Jamie; Næss-Schmidt, Erhard; Østergaard, Leif; Johansen-Berg, Heidi; Stagg, Charlotte; Nielsen, Jørgen Feldbæk; Ho, Yi Ching Lynn.

    Replace, Repair, Restore, Relieve: Bridging Clinical and Engineering Solutions in Neurorehabilitation. ed. / Winnie Jensen; Ole Kæseler Andersen; Metin Akay. Vol. 7 Springer, 2014. p. 23-24.

    Research output: Research - peer-reviewArticle in proceedings

  66. Published

    Capillary transit time heterogeneity in the cerebrum correlate with cognitive decline in AD. / Eskildsen, Simon Fristed; Gyldensted, Louise; Nagenthiraja, Kartheeban; Hansen, Mikkel; Dalby, Rikke; Frandsen, Jesper; Rodell, Anders; Gyldensted, Carsten; Jespersen, Sune Nørhøj; Mouridsen, Kim; Brændgaard, Hans; Østergaard, Leif.

    2014.

    Research output: Research - peer-reviewConference abstract for conference

  67. Published

    Reliable estimation of capillary transit time distributions using DSC-MRI. / Mouridsen, Kim; Hansen, Mikkel Bo; Østergaard, Leif; Jespersen, Sune Nørhøj.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 34, No. 9, 2014, p. 1511-21.

    Research output: Research - peer-reviewJournal article

  68. Published

    Biomarkers in the brain after mTBI: A multimodal MRI study. / Næss-Schmidt, Erhard; Blicher, Jakob; Tietze, Anna; Eskildsen, Simon Fristed; Hansen, Brian; Lund, Torben Ellegaard; Østergaard, Leif; Nielsen, Jørgen Feldbæk.

    2014. Poster session presented at 8th World Congress for NeuroRehabilitation, Istanbul, Turkey.

    Research output: Research - peer-reviewPoster

  69. Published

    Preserved Cerebral Microcirculation After Cardiac Arrest in an Asphyxial Rat Model. / Secher, Niels; Hansen, Frederik Boe; Tønnesen, Else Kirstine; Østergaard, Leif; Granfeldt, Asger.

    2014. Abstract from Scientific Sessions and Resuscitation Science Symposium of the American-Heart-Association Location, Chicago, United States.

    Research output: Research - peer-reviewConference abstract for conference

  70. Published

    Preserved Cerebral Microcirculation after Cardiac Arrest in an Asphyxial Rat Model. / Secher, Niels; Hansen, Frederik Boe; Tønnesen, Else Kirstine; Østergaard, Leif; Granfeldt, Asger.

    2014. Poster session presented at American Heart Association 2014, Chicago, United States.

    Research output: Research - peer-reviewPoster

  71. Published
  72. Published

    Application of Chemical Exchange Saturation Transfer (CEST) MRI in Acute Stroke to Visualize Tissue Acidosis and Infarction Risk. / Blicher, Jakob; Tietze, Anna; Mikkelsen, Irene Klærke; Østergaard, Leif; Strother, Megan; Smith, Seth; Donahue, Manus.

    2013. Abstract from World Congress of Neurology, Vienna, Austria.

    Research output: ResearchConference abstract for conference

  73. Published

    Intracortical GABA is decreased after stroke and further suppressed with successful rehabilitation. / Blicher, Jakob; Near, Jamie; Næss-Schmidt, Erhard; Østergaard, Leif; Johansen-Berg, Heidi; Ho, Yi-Ching Lynn.

    2013. Abstract from World Congress of Neurology, Vienna, Austria.

    Research output: ResearchConference abstract for conference

  74. Published

    Ultra-high field (1)H magnetic resonance imaging approaches for acute hypoxia. / Nielsen, Thomas; Nielsen, Niels Christian; Holm, Thomas Hellesøe; Ostergaard, Leif; Horsman, Michael R; Busk, Morten.

    In: Acta oncologica (Stockholm, Sweden), Vol. 52, No. 7, 30.08.2013, p. 1287-1292.

    Research output: Research - peer-reviewJournal article

  75. Published

    Very Low Cerebral Blood Volume Predicts Parenchymal Hematoma in Acute Ischemic Stroke. / Hermitte, Laure; Cho, Tae-Hee; Ozenne, Brice; Nighoghossian, Norbert; Mikkelsen, Irene Klærke; Ribe, Lars; Baron, Jean-Claude; Østergaard, Leif; Derex, Laurent; Hjort, Niels; Fiehler, Jens; Pedraza, Salvador; Hermier, Marc; Maucort-Boulch, Delphine; Berthezène, Yves.

    In: Stroke; a journal of cerebral circulation, Vol. 44, No. 8, 08.2013, p. 2318-2320.

    Research output: Research - peer-reviewJournal article

  76. Published

    Acute Stroke Imaging Research Roadmap II. / Wintermark, Max; Albers, Gregory W; Broderick, Joseph P; Demchuk, Andrew M; Fiebach, Jochen B; Fiehler, Jens; Grotta, James C; Houser, Gary; Jovin, Tudor G; Lees, Kennedy R; Lev, Michael H; Liebeskind, David S; Luby, Marie; Muir, Keith W; Parsons, Mark W; von Kummer, Rüdiger; Wardlaw, Joanna M; Wu, Ona; Yoo, Albert J; Alexandrov, Andrei V; Alger, Jeffry R; Aviv, Richard I; Bammer, Roland; Baron, Jean-Claude; Calamante, Fernando; Campbell, Bruce C V; Carpenter, Trevor C; Christensen, Søren; Copen, William A; Derdeyn, Colin P; Haley, E Clarke; Khatri, Pooja; Kudo, Kohsuke; Lansberg, Maarten G; Latour, Lawrence L; Lee, Ting-Yim; Leigh, Richard; Lin, Weili; Lyden, Patrick; Mair, Grant; Menon, Bijoy K; Michel, Patrik; Mikulik, Robert; Nogueira, Raul G; Østergaard, Leif; Pedraza, Salvador; Riedel, Christian H; Rowley, Howard A; Sanelli, Pina C; Sasaki, Makoto; Saver, Jeffrey L; Schaefer, Pamela W; Schellinger, Peter D; Tsivgoulis, Georgios; Wechsler, Lawrence R; White, Philip M; Zaharchuk, Greg; Zaidat, Osama O; Davis, Stephen M; Donnan, Geoffrey A; Furlan, Anthony J; Hacke, Werner; Kang, Dong-Wha; Kidwell, Chelsea; Thijs, Vincent N; Thomalla, Götz; Warach, Steven J; For the Stroke Imaging Research (STIR) and Virtual International Stroke Trials Archive (VISTA)-Imaging Investigators.

    In: Stroke; a journal of cerebral circulation, Vol. 44, No. 9, 16.07.2013, p. 2628-39.

    Research output: Research - peer-reviewJournal article

  77. Published

    Increased cerebral oxygen extraction capacity in patients with Alzheimer’s disease. / Eskildsen, Simon Fristed; Gyldensted, Louise; Nagenthiraja, Kartheeban; Frandsen, Jesper; Rodell, Anders; Gyldensted, Carsten; Jespersen, Sune Nørhøj; Mouridsen, Kim; Brændgaard, Hans; Østergaard, Leif.

    2013. Abstract from Alzheimer's Association International Conference, Boston, United States.

    Research output: Research - peer-reviewConference abstract for conference

  78. Published

    Capillary Dysfunction in Alzheimer's Disease. / Østergaard, Leif; Nagenthiraja, Kartheeban; Gyldensted, Louise; Rodell, Anders; Gyldensted, Carsten; Jespersen, Sune Nørhøj; Mouridsen, Kim; Brændgaard, Hans; West, Mark J.

    2013. Poster session presented at Alzheimer's Association International Conference, Boston, United States.

    Research output: Research - peer-reviewPoster

  79. Published
  80. Published

    Acute Stroke : Automatic Perfusion Lesion Outlining Using Level Sets. / Mouridsen, Kim; Nagenthiraja, Kartheeban; Jónsdóttir, Kristjana Yr; Ribe, Lars R; Neumann, Anders B; Hjort, Niels; Østergaard, Leif.

    In: Radiology, Vol. 269, No. 2, 17.05.2013, p. 404-12.

    Research output: Research - peer-reviewJournal article

  81. Published

    Application of Chemical Exchange Saturation Transfer (CEST) MRI in Acute Human Stroke Patients Demonstrates New Potential for Visualization of Tissue Acidosis and Infarction Risk. / Donahue, Manus; Tietze, Anna; Mikkelsen, Irene Klærke; Østergaard, Leif; Strother, Megan; Smith, Seth; Blicher, Jakob.

    2013. Abstract from ISMRM 2013, Salt Lake City, United States.

    Research output: Research - peer-reviewConference abstract for conference

  82. Published

    Accuracy and reliability assessment of CT and MR perfusion analysis software using a digital phantom. / Kudo, Kohsuke; Christensen, Søren; Sasaki, Makoto; Østergaard, Leif; Shirato, Hiroki; Ogasawara, Kuniaki; Wintermark, Max; Warach, Steven; Stroke Imaging Repository (STIR) Investigators.

    In: Radiology, Vol. 267, No. 1, 04.2013, p. 201-11.

    Research output: Research - peer-reviewJournal article

  83. Published

    The role of the cerebral capillaries in acute ischemic stroke: the extended penumbra model. / Østergaard, Leif; Jespersen, Sune Nørhøj; Mouridsen, Kim; Mikkelsen, Irene Klærke; Jónsdóttir, Kristjana Ýr; Tietze, Anna; Blicher, Jakob; Aamand, Rasmus; Hjort, Niels; Iversen, Nina Kerting; Cai, Changsi; Hougaard, Kristina Dupont; Simonsen, Claus Ziegler; Weitzel-Mudersbach, Paul von; Modrau, Boris; Nagenthiraja, Kartheeban; Ribe, Lars Riisgaard; Hansen, Mikkel Bo; Bekke, Susanne Lise; Dahlmann, Martin Gervais; Puig, Josep; Pedraza, Salvador; Serena, Joaquín; Cho, Tae-Hee; Siemonsen, Susanne; Thomalla, Götz; Fiehler, Jens; Nighoghossian, Norbert; Andersen, Grethe.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 33, No. 5, 27.02.2013, p. 635.

    Research output: Research - peer-reviewJournal article

  84. Published

    The capillary dysfunction hypothesis of Alzheimer's disease. / Østergaard, Leif; Aamand, Rasmus; Gutiérrez Jiménez, Eugenio ; Ho, Yi Ching Lynn; Blicher, Jakob; Madsen, Søren Møller; Nagenthiraja, Kartheeban; Dalby, Rikke Beese; Drasbek, Kim Ryun; Møller, Arne; Brændgaard, Hans; Mouridsen, Kim; Jespersen, Sune Nørhøj; Jensen, Morten Skovgaard; West, Mark J.

    In: Neurobiology of Aging, Vol. 34, No. 4, 12.01.2013, p. 1018-31.

    Research output: Research - peer-reviewJournal article

  85. Published

    Vigtige metoder til undersøgelse af hjernen. / Hansen, Brian; Østergaard, Leif.

    Hjernen - fra celle til samfund. ed. / Henriette Blæsild Vuust. 2013. p. 164-167.

    Research output: CommunicationBook chapter

  86. Published

    Remote ischemic perconditioning in thrombolysed stroke patients : Randomized study of activating endogenous neuroprotection - design and MRI measurements. / Hougaard, K D; Hjort, N; Zeidler, D; Sørensen, L; Nørgaard, A; Thomsen, R B; Jonsdottir, K; Mouridsen, K; Hansen, T M; Cho, T-H; Nielsen, T T; Bøtker, H E; Østergaard, Leif; Andersen, Grethe.

    In: International Journal of Stroke, Vol. 8, No. 2, 2013, p. 141-6.

    Research output: Research - peer-reviewJournal article

  87. Published

    Automated decision-support system for prediction of treatment responders in acute ischemic stroke. / Nagenthiraja, Kartheeban; Walcott, B. P. ; Hansen, Mikkel Bo; Østergaard, Leif; Mouridsen, Kim.

    In: Frontiers in Neurology, Vol. 4, 140, 2013.

    Research output: Research - peer-reviewJournal article

  88. Published

    Dose optimization for using the contrast agent gadofosveset in magnetic resonance imaging (MRI) of domestic pig brain. / Poulsen, Erik Søndergaard; Alstrup, Aage Kristian Olsen; Zeidler, Dora; Hjort, Niels; Østergaard, Leif.

    In: Scandinavian Journal of Laboratory Animal Science, Vol. 4, 2013, p. 1-9.

    Research output: Research - peer-reviewJournal article

  89. Published
  90. Published

    Changes in regional brain volume three months after stroke. / Brodtmann, Amy; Pardoe, Heath ; Li, Qi; Lichter, Renee; Østergaard, Leif; Cumming, Toby.

    In: Journal of the neurological sciences, Vol. 322, No. 1-2, 15.11.2012, p. 122-8.

    Research output: Research - peer-reviewJournal article

  91. Published

    Visualization of altered neurovascular coupling in chronic stroke patients using multimodal functional MRI. / Blicher, Jakob; Stagg, Charlotte J; O'Shea, Jacinta; Ostergaard, Leif; Macintosh, Bradley J; Johansen-Berg, Heidi; Jezzard, Peter; Donahue, Manus J.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 32, No. 11, 08.2012, p. 2044-2054.

    Research output: Research - peer-reviewJournal article

  92. Published

    CT and MR perfusion can discriminate severe cerebral hypoperfusion from perfusion absence : evaluation of different commercial software packages by using digital phantoms. / Uwano, I; Kudo, Kohsuke; Sasaki, M; Christensen, Søren; Østergaard, Leif; Ogasawara, K; Ogawa, A.

    In: Neuroradiology, Vol. 54, No. 5, 01.05.2012, p. 467-74.

    Research output: Research - peer-reviewJournal article

  93. Published

    Fully automated DWI-PWI mismatch quantification in acute stroke. / Nagenthiraja, Kartheeban; Ribe, Lars Riisgaard; Hougaard, Kristina Dupont; Østergaard, Leif; Mouridsen, Kim.

    2012. Abstract from International Society of Magnetic Resonance in Medicine 2012 , Melbourne, Australia.

    Research output: Research - peer-reviewConference abstract for conference

  94. Published

    Elevated T2-values in MRI of stroke patients shortly after symptom onset do not predict irreversible tissue infarction. / Siemonsen, Susanne ; Löbel, Ulricke; Sedlacik, Jan; Forkert, Nils D.; Mouridsen, Kim; Østergaard, Leif; Thomalla, Goetz; Fiehler, Jens.

    In: Brain, Vol. 135, No. 6, 15.03.2012, p. 1981-89.

    Research output: Research - peer-reviewJournal article

  95. Published

    Accumulation of magnetic iron oxide nanoparticles coated with variably sized polyethylene glycol in murine tumors. / Larsen, Esben Kjær Unmack; Nielsen, Thomas; Wittenborn, Thomas; Rydtoft, Louise Munk; Lokanathan, Arcot R.; Hansen, Line; Østergaard, Leif; Kingshott, Peter; Howard, Kenneth A; Besenbacher, Flemming; Nielsen, Niels Christian; Kjems, Jørgen.

    In: Nanoscale, Vol. 4, No. 7, 06.03.2012, p. 2352-2361 .

    Research output: Research - peer-reviewJournal article

  96. Published

    The roles of cerebral blood flow, capillary transit time heterogeneity, and oxygen tension in brain oxygenation and metabolism. / Jespersen, Sune Nørhøj; Østergaard, Leif.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 32, No. 2, 01.02.2012, p. 264-277.

    Research output: Research - peer-reviewJournal article

  97. Published

    A Fully Automated Penumbra Segmentation Tool. / Nagenthiraja, Kartheeban; Ribe, Lars Riisgaard; Hougaard, Kristina Dupont; Østergaard, Leif; Mouridsen, Kim.

    2012.

    Research output: Research - peer-reviewConference abstract for conference

  98. Published

    Assessing Response to Stroke Thrombolysis : Validation of 24-Hour Multimodal Magnetic Resonance Imaging. / Campbell, Bruce C. V.; Tu, Hans T. H. ; Christensen, Søren ; Desmond, Patricia M.; Levi, Christopher R.; Blandin, Christopher F.; Hjort, Niels; Ashkanian, Mahmoud; Sølling, Christine; Donnan, Geoffrey A.; Davis, Stephen M. ; Østergaard, Leif; Parsons, Mark W.

    In: Archives of Neurology, Vol. 69, No. 1, 01.01.2012, p. 46-50.

    Research output: Research - peer-reviewJournal article

  99. Published

    Post-stroke fMRI, a comparison of BOLD, cerebral blood flow, and cerebral blood volume responses. / Blicher, Jakob; Stagg, Charlotte; O'Shea, Jacinta; Østergaard, Leif; MacIntosh, Bradley; Johansen-Berg, Heidi; Jezzard, Peter; Donahue, Manus.

    2012. Abstract from Dansk Neurologisk Selskab, Vejle, Denmark.

    Research output: Research - peer-reviewConference abstract for conference

  100. Published

    The Göttingen minipig in translational neuroscience. / Bro, Anette; Sørensen, Jens Christian Hedemann; Nielsen, Mette Slot; Rosendahl, Frederikke; Deding, Dorthe; Ettrup, Kåre Schmidt; Jensen, Kristian Nørholm; Jørgensen, Rasmus Langelund; Glud, Andreas Nørgaard; Meidahl, Anders Christian Nørgaard; Meier, Kaare; Moberg Fitting, Lise; Møller, Arne; Alstrup, Aage Kristian Olsen; Østergaard, Leif; Bjarkam, Carsten Reidies.

    In: Ellegaard Newsletter, Vol. 38, 2012, p. 8-9.

    Research output: ResearchReview

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