Gregers Wegener

  1. 2018
  2. E-pub ahead of print

    Cannabidiol Induces Rapid and Sustained Antidepressant-Like Effects Through Increased BDNF Signaling and Synaptogenesis in the Prefrontal Cortex. / Sales, Amanda J; Fogaça, Manoela V; Sartim, Ariandra G; Pereira, Vitor S; Wegener, Gregers; Guimarães, Francisco S; Joca, Sâmia R L.

    In: Molecular Neurobiology, 04.06.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  3. E-pub ahead of print

    Sex-dependent behavior, neuropeptide profile and antidepressant response in rat model of depression. / Sanchez, Connie; El Khoury, Aram; Hassan, Moustapha; Wegener, Gregers; Mathe, Aleksander A.

    In: Behavioural Brain Research, 29.05.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  4. Published

    A Preclinical Study of Casein Glycomacropeptide as a Dietary Intervention for Acute Mania. / Liebenberg, Nico; Jensen, Erik; Larsen, Erik Roj; Kousholt, Birgitte Saima; Pereira, Vitor Silva; Fischer, Christina Weide; Wegener, Gregers.

    In: International Journal of Neuropsychopharmacology, Vol. 21, No. 5, 01.05.2018, p. 473-484.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  5. Published

    Probiotics Affect One-Carbon Metabolites and Catecholamines in a Genetic Rat Model of Depression. / Tillmann, Sandra; Awwad, Hussain M; Eskelund, Amanda R; Treccani, Giulia; Geisel, Juergen; Wegener, Gregers; Obeid, Rima.

    In: Molecular Nutrition & Food Research, 07.04.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  6. Published

    Probiotics - a novel antidepressant? Lessons from preclinical studies. / Abildgaard, Anders; Elfving, Betina; Müller, Heidi Kaastrup; Hokland, Marianne; Lund, Sten; Wegener, Gregers.

    2018. 11-12 Abstract from SCNP 59th Annual Meeting 2018, Aarhus, Denmark.

    Research output: Contribution to conferenceConference abstract for conference

  7. E-pub ahead of print

    A critical role of mitochondria in BDNF-associated synaptic plasticity after one-week vortioxetine treatment. / Chen, Fenghua; Danladi, Jibrin; Ardalan, Maryam; Elfving, Betina; Müller, Heidi K; Wegener, Gregers; Sanchez, Connie; Nyengaard, Jens R.

    In: International Journal of Neuropsychopharmacology, 05.03.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  8. Published

    Syringe-feeding as a novel delivery method for accurate individual dosing of probiotics in rats. / Tillmann, S; Wegener, G.

    In: Beneficial Microbes, Vol. 9, No. 2, 02.03.2018, p. 311-315.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  9. Published

    Mitochondria are critical for BDNF-mediated Synaptic and Vascular plasticity of Hippocampus following Repeated Electroconvulsive Seizures. / Chen, Fenghua; Ardalan, Maryam; Elfving, Betina; Wegener, Gregers; M Madsen, Torsten; Nyengaard, Jens R.

    In: International Journal of Neuropsychopharmacology, Vol. 21, No. 3, 01.03.2018, p. 291-304.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  10. Published

    Erythropoietin prevents the effect of chronic restraint stress on the number of hippocampal CA3c dendritic terminals-relation to expression of genes involved in synaptic plasticity, angiogenesis, inflammation, and oxidative stress in male rats. / Aalling, Nadia; Hageman, Ida; Miskowiak, Kamilla Woznica; Orlowski, Dariusz; Wegener, Gregers; Wortwein, Gitta.

    In: Journal of Neuroscience Research, 01.2018.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  11. 2017
  12. Published

    Acta Neuropsychiatrica and social media. / Wegener, Gregers.

    In: Acta Neuropsychiatrica, Vol. 29, No. 6, 12.2017, p. 323.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  13. Published

    Ketamine and aminoguanidine differentially affect Bdnf and Mtor gene expression in the prefrontal cortex of adult male rats. / Silva Pereira, Vitor; Elfving, Betina; Joca, Sâmia R L; Wegener, Gregers.

    In: European Journal of Pharmacology, Vol. 815, 15.11.2017, p. 304-311.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  14. E-pub ahead of print

    The microbial metabolite indole-3-propionic acid improves glucose metabolism in rats, but does not affect behaviour. / Abildgaard, Anders; Elfving, Betina; Hokland, Marianne; Wegener, Gregers; Lund, Sten.

    In: Archives of Physiology and Biochemistry, 07.11.2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  15. Published

    ZL006, a small molecule inhibitor of PSD-95/nNOS interaction, does not induce antidepressant-like effects in two genetically predisposed rat models of depression and control animals. / Tillmann, Sandra; Pereira, Vitor Silva; Liebenberg, Nico; Christensen, Anne Karina; Wegener, Gregers.

    In: P L o S One, Vol. 12, No. 8, 03.08.2017, p. 1-17.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  16. Published

    Discovery versus implementation research on mental disorders in low- and middle-income countries. / Stein, Dan J; Wegener, Gregers.

    In: Acta Neuropsychiatrica, Vol. 29, No. 4, 08.2017, p. 191-192.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  17. Published

    Drugs with antidepressant properties affect tryptophan metabolites differently in rodent models with depression-like behavior. / Eskelund, Amanda; Li, Yan; Budac, David P.; Müller, Heidi K.; Gulinello, Maria; Sanchez, Connie; Wegener, Gregers.

    In: Journal of Neurochemistry, Vol. 142, No. 1, 01.07.2017, p. 118-131.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  18. Published

    Chronic maternal inflammation or high-fat-feeding programs offspring obesity in a sex-dependent manner. / Dudele, A; Hougaard, K S; Kjølby, M; Hokland, M; Winther, G; Elfving, B; Wegener, G; Nielsen, A L; Larsen, A; Nøhr, M K; Pedersen, S B; Wang, T; Lund, S.

    In: International Journal of Obesity, Vol. 41, No. 9, 07.06.2017, p. 1420-1426.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  19. Published

    Elevated dopamine D1 receptor availability in striatum of Göttingen minipigs after electroconvulsive therapy. / Landau, Anne M.; Alstrup, Aage Kristian Olsen; Audrain, Héléne; Jakobsen, Steen; Simonsen, Mette; Møller, Arne; Videbech, Poul B; Wegener, Gregers; Gjedde, Albert; Doudet, Doris J.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 38, No. 5, 27.05.2017, p. 881-887.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  20. Published

    Mice heterozygous for an inactivated allele of the schizophrenia associated Brd1 gene display selective cognitive deficits with translational relevance to schizophrenia. / Qvist, Per; Rajkumar, Anto P.; Redrobe, John P; Nyegaard, Mette; Christensen, Jane H.; Mors, Ole; Wegener, Gregers; Didriksen, Michael; Børglum, Anders D.

    In: Neurobiology of Learning and Memory, Vol. 141, 01.05.2017, p. 44-52.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  21. Published

    Probiotic treatment protects against the pro-depressant-like effect of high-fat diet in Flinders Sensitive Line rats. / Abildgaard, Anders; Elfving, Betina; Hokland, Marianne; Lund, Sten; Wegener, Gregers.

    In: Brain, Behavior, and Immunity, Vol. 65, 25.04.2017, p. 33-42.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  22. Published

    3D analysis of synaptic vesicle density and distribution after acute foot-shock stress by using serial section transmission electron microscopy. / Khanmohammadi, M; Darkner, S; Nava, N; Nyengaard, J R; Wegener, G; Popoli, M; Sporring, J.

    In: Journal of Microscopy, Vol. 265, No. 1, 01.2017, p. 101–110.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  23. Published

    Gene expression related to serotonergic and glutamatergic neurotransmission is altered in the Flinders Sensitive Line rat model of depression : Effect of ketamine. / du Jardin, Kristian Gaarn; Müller, Heidi Kaastrup; Sanchez, Connie; Wegener, Gregers; Elfving, Betina.

    In: Synapse, Vol. 71, No. 1, 01.2017, p. 37–45.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  24. Published

    The expression of plasticity-related genes in an acute model of stress is modulated by chronic desipramine in a time-dependent manner within medial prefrontal cortex. / Nava, Nicoletta; Treccani, Giulia; Müller, Heidi Kaastrup; Popoli, Maurizio; Wegener, Gregers; Elfving, Betina.

    In: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 27, No. 1, 01.2017, p. 19-28.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  25. Published

    A dual inhibitor of FAAH and TRPV1 channels shows dose-dependent effect on depression-like behaviour in rats. / Kirkedal, Christian; Wegener, Gregers; Moreira, Fabricio; Joca, Sâmia Regiane Lourenco; Liebenberg, Nico.

    In: Acta Neuropsychiatrica, Vol. 29, No. 6, 2017, p. 324-329.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  26. Published

    Probiotic treatment reduces depressive-like behaviour in rats independently of diet. / Abildgaard, Anders; Elfving, Betina; Hokland, Marianne; Wegener, Gregers; Lund, Sten.

    In: Psychoneuroendocrinology, Vol. 79, 2017, p. 40-48.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  27. Published

    Rapid Antidepressant Effect of Ketamine Correlates with Astroglial Plasticity in the Hippocampus. / Ardalan, Maryam; Rafati, Ali H; Nyengaard, Jens R; Wegener, Gregers.

    In: British Journal of Pharmacology, Vol. 174, No. 6, 2017.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  28. Published

    S-Ketamine Mediates Its Acute and Sustained Antidepressant-Like Activity through a 5-HT1B Receptor Dependent Mechanism in a Genetic Rat Model of Depression. / du Jardin, Kristian G; Liebenberg, Nico; Cajina, Manuel; Müller, Heidi K; Elfving, Betina; Sanchez, Connie; Wegener, Gregers.

    In: Frontiers in Pharmacology, Vol. 8, 2017, p. 978.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  29. Published

    S-Ketamine Rapidly Reverses Synaptic and Vascular Deficits of Hippocampus in Genetic Animal Model of Depression. / Ardalan, Maryam; Wegener, Gregers; H Rafati, Ali; R Nyengaard, Jens.

    In: International Journal of Neuropsychopharmacology, Vol. 20, No. 3, 2017, p. 247-256.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  30. Published

    Systematic evaluation of skeletal fractures caused by induction of electroconvulsive seizures in rat state a need for attention and refinement of the procedure. / Ekemohn, M; Nielsen, Marie Kjær; Grahm, M; Tingström, A; Kousholt, Birgitte S.; Wegener, Gregers; Bay-Richter, Cecilie.

    In: Acta Neuropsychiatrica, Vol. 29, No. 6, 2017, p. 363-373.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  31. Published

    Temporal Dynamics of Acute Stress-Induced Dendritic Remodeling in Medial Prefrontal Cortex and the Protective Effect of Desipramine. / Nava, Nicoletta; Treccani, Giulia; Alabsi, Abdelrahman; Elfving, Betina; Müller, Heidi Kaastrup; Popoli, Maurizio; Wegener, Gregers; Nyengaard, Jens Randel.

    In: Cerebral Cortex, Vol. 27, No. 1, 2017, p. 694-705.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  32. 2016
  33. Published

    MicroRNA 101b is downregulated in the prefrontal cortex of a genetic model of depression and targets the glutamate transporter SLC1A1 (EAAT3) in vitro. / Wei, Ya Bin; Melas, Philippe A; Villaescusa, J Carlos; Liu, Jia Jia; Xu, Ning; Christiansen, Søren Hofman; Elbrønd-Bek, Heidi; Woldbye, David Paul Drucker; Wegener, Gregers; Mathé, Aleksander A; Lavebratt, Catharina.

    In: International Journal of Neuropsychopharmacology, Vol. 19, No. 12, 01.12.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  34. Published

    Potential involvement of serotonergic signaling in ketamine's antidepressant actions : A critical review. / du Jardin, Kristian Gaarn; Müller, Heidi Kaastrup; Elfving, Betina; Dale, Elena; Wegener, Gregers; Sanchez, Connie.

    In: Progress in Neuro-Psychopharmacology & Biological Psychiatry, Vol. 71, 03.11.2016, p. 27-38.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  35. Published

    Elevation of Il6 is associated with disturbed let-7 biogenesis in a genetic model of depression. / Wei, Y B; Liu, J J; Villaescusa, J C; Åberg, E; Brené, S; Wegener, G; Mathé, A A; Lavebratt, C.

    In: Translational Psychiatry, Vol. 6, No. 8, 17.08.2016, p. e869.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  36. Published

    Antidepressant efficacy of high and low frequency transcranial magnetic stimulation in the FSL/FRL genetic rat model of depression. / Pedersen, Marie Louise Hesselberg; Wegener, Gregers; Buchholtz, Poul Erik.

    In: Behavioural Brain Research, Vol. 314, 27.07.2016, p. 45-51.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  37. Published

    Differential interaction with the serotonin system by S-ketamine, vortioxetine, and fluoxetine in a genetic rat model of depression. / du Jardin, Kristian Gaarn; Liebenberg, Nico; Müller, Heidi Kaastrup; Elfving, Betina; Sanchez, Connie; Wegener, Gregers.

    In: Psychopharmacology, Vol. 233, No. 14, 07.2016, p. 2813-2825.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  38. Published

    A single dose of vortioxetine, but not ketamine or fluoxetine, increases plasticity-related gene expression in the rat frontal cortex. / du Jardin, Kristian Gaarn; Müller, Heidi Kaastrup; Sanchez, Connie; Wegener, Gregers; Elfving, Betina.

    In: European Journal of Pharmacology, Vol. 786, 25.05.2016, p. 29-35.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  39. Published

    Female Flinders Sensitive Line rats show estrous cycle-independent depression-like behavior and altered tryptophan metabolism. / Eskelund, Amanda; Budac, David P; Sanchez, Connie; Elfving, Betina; Wegener, Gregers.

    In: Neuroscience, Vol. 329, 19.05.2016, p. 337-348.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  40. Published

    Vortioxetine promotes early changes in dendritic morphology compared to fluoxetine in rat hippocampus. / Chen, Fenghua; du Jardin, Kristian Gaarn; Waller, Jessica A; Sanchez, Connie; Nyengaard, Jens R; Wegener, Gregers.

    In: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 26, No. 2, 02.2016, p. 234-245.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  41. Published

    Differential expression of postsynaptic NMDA and AMPA receptor subunits in the hippocampus and prefrontal cortex of the Flinders Sensitive Line rat model of depression. / Treccani, Giulia; du Jardin, Kristian Gaarn; Wegener, Gregers; Kaastrup Müller, Heidi.

    In: Synapse, Vol. 70, 2016, p. 471-474.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  42. Published

    Endogenous 5-HT receptor stimulation is critical for the antidepressant-like effect of ketamine but not vortioxetine. / du Jardin, Kristian Gaarn; Liebenberg, Nico; Müller, Heidi Kaastrup; Elfving, Betina; Sánchez, Connie; Wegener, Gregers.

    In: Acta Neuropsychiatrica, Vol. 28, No. S2, 2016, p. 19-20.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journal

  43. Published

    Functional and morphological changes induced by ketamine in the rat hippocampus. / Treccani, Giulia; Liebenberg, Nico; Tillmann, Sandra; Musazzi, L; Milanese, M; Chen, Fenghua; Elfving, Betina; Wegener, Gregers; Nyengaard, Jens Randel; Popoli, M; Müller, Heidi Kaastrup.

    2016. Poster session presented at 57th Annual Conference of the SCNP, Aarhus, Denmark.

    Research output: Contribution to conferencePoster

  44. Published
  45. Published

    Mirroring. / Wegener, Charlotte; Wegener, Gregers.

    Creativity — A New Vocabulary. ed. / Vlad Petre Glăveanu; Lene Tanggaard; Charlotte Wegener. London : Palgrave Macmillan, 2016. p. 87-95.

    Research output: Contribution to book/anthology/report/proceedingBook chapter

  46. Published

    Neonatal domoic acid alters in vivo binding of [(11)C]yohimbine to α2-adrenoceptors in adult rat brain. / Thomsen, Majken B; Lillethorup, Thea P; Jakobsen, Steen; Nielsen, Erik H; Simonsen, Mette; Wegener, Gregers; Landau, Anne M; Tasker, Andrew.

    In: Psychopharmacology, Vol. 233, No. 21, 2016, p. 3779-3785.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  47. Published

    Neurovascular plasticity of the hippocampus one week after a single dose of ketamine in genetic rat model of depression. / Ardalan, Maryam; Wegener, Gregers; Polsinelli , Benedetta; Madsen, Torsten Meldgaard; Nyengaard, Jens Randel.

    In: The Hippocampus, Vol. 26, No. 11, 2016, p. 1414-1423.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  48. Published

    Understanding in vivo modelling of depression in non-human animals: a systematic review protocol. / Bannach-Brown, Alexandra; Liao, Jing; Wegener, Gregers; Macleod, Malcolm.

    In: Evidence-based Preclinical Medicine, Vol. 3, No. 2, 2016, p. 20-27.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  49. 2015
  50. Published

    Behavioral and systemic consequences of long-term inflammatory challenge. / Fischer, Christina W; Elfving, Betina; Lund, Sten; Wegener, Gregers.

    In: Journal of neuroimmunology, Vol. 288, 15.11.2015, p. 40-6.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  51. Published

    Chronic exposure to low doses of lipopolysaccharide and high-fat feeding increases body mass without affecting glucose tolerance in female rats. / Dudele, Anete; Fischer, Christina W; Elfving, Betina; Wegener, Gregers; Wang, Tobias; Lund, Sten.

    In: Physiological Reports, Vol. 3, No. 11, 11.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  52. Published

    Interferon-alpha treatment induces depression-like behaviour accompanied by elevated hippocampal quinolinic acid levels in rats. / Fischer, Christina Weide; Eskelund, Amanda; Budac, David P; Tillmann, Sandra; Liebenberg, Nico; Elfving, Betina; Wegener, Gregers.

    In: Behavioural Brain Research, Vol. 293, 15.10.2015, p. 166-172.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  53. Published

    P. 2. e. 001 Differentiated antidepressant-like profiles of ketamine, fluoxetine and vortioxetine in Flinders Sensitive Line (FSL) rats depleted of endogenous 5-HT. / Du Jardin, K. G.; Liebenberg, N.; Müller, Heidi Kaastrup; Elfving, B.; Wegener, G.; Sanchez, C.

    In: European Neuropsychopharmacology, Vol. 25, 09.2015, p. S431-S431.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journal

  54. Published

    Astroglial Control of the Antidepressant-Like Effects of Prefrontal Cortex Deep Brain Stimulation. / Etiévant, A; Oosterhof, C; Bétry, C; Abrial, E; Novo-Perez, M; Rovera, R; Scarna, H; Devader, C; Mazella, J; Wegener, G; Sánchez, C; Dkhissi-Benyahya, O; Gronfier, C; Coizet, V; Beaulieu, J M; Blier, P; Lucas, G; Haddjeri, N.

    In: EBioMedicine, Vol. 2, No. 8, 08.2015, p. 896-906.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  55. Published

    Neonatal domoic acid decreases in vivo binding of [11C]yohimbine to α2 adrenoceptors in adult rat brain. / Thomsen, Majken; Lillethorup, Thea Pinholt; Jakobsen, Steen; Nielsen, Erik Holm Toustrup; Simonsen, Mette; Wegener, Gregers; Tasker, Andrew; Landau, Anne M.

    2015. Poster session presented at NeuroConX, Charlottetown, Prince Edward Island, Canada.

    Research output: Contribution to conferencePoster

  56. Published

    Chronic lipopolysaccharide infusion fails to induce depressive-like behaviour in adult male rats. / Fischer, Christina Weide; Liebenberg, Nico; Madsen, Anne Mette; Müller, Heidi Kaastrup; Lund, Sten; Wegener, Gregers.

    In: Acta Neuropsychiatrica (Print), Vol. 27, No. 3, 06.2015, p. 189.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  57. Published

    Neonatal domoic acid decreases in vivo binding of [11C]yohimbine to α2 adrenoceptors in adult rat brain. / Thomsen, Majken; Lillethorup, Thea Pinholt; Jakobsen, Steen; Nielsen, Erik Holm Toustrup; Simonsen, Mette; Wegener, Gregers; Tasker, Andrew; Landau, Anne M.

    2015. Poster session presented at Brain & Brain PET 2015, Vancouver, Canada.

    Research output: Contribution to conferencePoster

  58. Published
  59. Published

    α2-adrenoceptor binding in Flinders-sensitive line compared with Flinders-resistant line and Sprague-Dawley rats. / Lillethorup, Thea Pinholt; Iversen, Peter; Wegener, Gregers; Doudet, Doris Jeanne Marie; Landau, Anne Marlene.

    In: Acta Neuropsychiatrica (Print), 23.04.2015, p. 1-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  60. Published

    Potential roles for Homer1 and Spinophilin in the preventive effect of electroconvulsive seizures on stress-induced CA3c dendritic retraction in the hippocampus. / Kaastrup Müller, Heidi; Orlowski, Dariusz; Reidies Bjarkam, Carsten; Wegener, Gregers; Elfving, Betina.

    In: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 24, No. 8, 18.04.2015, p. 1324-1331.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  61. Published

    Decreased in vivo α2 adrenoceptor binding in the Flinders Sensitive Line rat model of depression. / Landau, Anne M.; Phan, Jenny-Ann; Iversen, Peter; Lillethorup, Thea P; Simonsen, Mette; Wegener, Gregers; Jakobsen, Steen; Doudet, Doris J.

    In: Neuropharmacology, Vol. 91, 04.2015, p. 97-102.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  62. Published

    Neonatal domoic acid increases receptor density of α2 adrenoceptors and GABAA α5 receptors in limbic brain regions of adult rats. / Thomsen, Majken; Lillethorup, Thea Pinholt; Wegener, Gregers; Tasker, Andrew; Landau, Anne M.

    2015. Poster session presented at 56th Annual Congress of the Scandinavian College of Neuro-Psychopharmacology, Copenhagen, Denmark.

    Research output: Contribution to conferencePoster

  63. Published

    Selective breeding for high anxiety introduces a synonymous SNP that increases neuropeptide s receptor activity. / Slattery, David A; Naik, Roshan R; Grund, Thomas; Yen, Yi-Chun; Sartori, Simone B; Füchsl, Andrea; Finger, Beate C; Elfving, Betina; Nordemann, Uwe; Guerrini, Remo; Calo, Girolamo; Wegener, Gregers; Mathé, Aleksander A; Singewald, Nicolas; Czibere, Ludwig; Landgraf, Rainer; Neumann, Inga D.

    In: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, No. 11, 18.03.2015, p. 4599-613.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  64. Published

    Dietary magnesium deficiency affects gut microbiota and anxiety-like behaviour in C57BL/6N mice. / Pyndt Jørgensen, Bettina; Winther, Gudrun; Kihl, Pernille; Nielsen, Dennis S; Wegener, Gregers; Hansen, Axel K; Sørensen, Dorte B.

    In: Acta Neuropsychiatrica (Print), 16.03.2015, p. 1-5.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  65. Published

    Expression of inflammatory markers in a genetic rodent model of depression. / Strenn, Nina; Suchankova, Petra; Nilsson, Staffan; Fischer, Christina; Wegener, Gregers; Mathé, Aleksander A; Ekman, Agneta.

    In: Behavioural Brain Research, Vol. 281, 15.03.2015, p. 348–357.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  66. Published

    Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression. / Lillethorup, Thea P; Iversen, Peter; Fontain, Jesper; Wegener, Gregers; Doudet, Doris J; Landau, Anne M.

    In: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 03.2015, p. 404-412.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  67. Published

    Dietary magnesium deficiency alters gut microbiota and leads to depressive-like behaviour. / Winther, Gudrun; Pyndt Jørgensen, Betina M; Elfving, Betina; Nielsen, Denis Sandris; Kihl, Pernille; Lund, Sten; Sørensen, Dorte Bratbo; Wegener, Gregers.

    In: Acta Neuropsychiatrica (Print), 18.02.2015, p. 1-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  68. Published

    Chronic restraint stress increases the protein expression of VEGF and its receptor VEGFR-2 in the prefrontal cortex. / Elfving, Betina; Jakobsen, Jakob Lerche; Madsen, Jens Christian Bredahl; Wegener, Gregers; Müller, Heidi Kaastrup.

    In: Synapse, 05.02.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  69. Published

    Antidepressant-like effects induced by NMDA receptor blockade and NO synthesis inhibition in the ventral medial prefrontal cortex of rats exposed to the forced swim test. / Pereira, Vitor Silva; Romano, Angélica; Wegener, Gregers; Joca, Sâmia.

    In: Psychopharmacology, 16.01.2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  70. Published

    Antidepressant-Like Effect of Sodium Butyrate is Associated with an Increase in TET1 and in 5-Hydroxymethylation Levels in the Bdnf Gene. / Wei, Yabin; Melas, Philippe A; Wegener, Gregers; Mathé, Aleksander A; Lavebratt, Catharina.

    In: International Journal of Neuropsychopharmacology, Vol. 18, No. 2, 2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  71. Published

    Atypical neurotransmitters and the neurobiology of depression. / Joca, Sâmia; Moreira, Fabricio A; Wegener, Gregers.

    In: CNS & neurological disorders drug targets, Vol. 14 (8), 2015, p. 1001-11.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  72. Published

    Differentiated antidepressant-like profiles of ketamine, fluoxetine and vortioxetine in Flinders Sensitive Line rats depleted of endogenous 5-HT. / du Jardin, Kristian Gaarn; Liebenberg, Nico; Müller, Heidi Kaastrup; Elfving, Betina; Sánchez, Connie; Wegener, Gregers.

    In: Acta Neuropsychiatrica, Vol. 27, No. S1, 2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journal

  73. Published

    GLP-1 receptor agonists have a sustained stimulatory effect on corticosterone release after chronic treatment. / Krass, Maarja; Volke, Annika; Rünkorg, Kertu; Wegener, Gregers; Lund, Sten; Abildgaard, Anders; Vasar, Eero; Volke, Vallo.

    In: Acta Neuropsychiatrica (Print), Vol. 27, No. 1, 2015, p. 25-32.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  74. Published
  75. Published

    Større metodisk tilgang efterlyses i dyrestudier. / Kousholt, Birgitte; Wegener, Gregers.

    In: Dansk Veterinaertidsskrift, Vol. 98, No. 12, 2015, p. 27-30.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  76. Published

    Telomerase dysregulation in the hippocampus of a rat model of depression. Normalization by lithium. / Wei, Yabin; Backlund, Lena; Wegener, Gregers; Mathe, Aleksander A; Lavebratt, Catharina.

    In: International Journal of Neuropsychopharmacology, 2015.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  77. Published

    The characteristic secret whistles of a depressive-like rat. / Kai, Linda Marie; Elfving, Betina; Wegener, Gregers.

    2015. Poster session presented at Psykiatriens 10. forskningsdag, Risskov, Denmark.

    Research output: Contribution to conferencePoster

  78. Published

    The stress impact on synaptic function and brain architecture; a key to mood and anxiety disorders. / Musazzi, L; Treccani, Giulia; Milanese, M; Perego, C; Nava, Nicoletta; Tornese, Paolo; Sala, N; Bazzini, C; Malgaroli, A; Nyengaard, Jens Randel; Wegener, Gregers; Bonanno, G; Popoli, M.

    2015. Poster session presented at 28th Congress of the European-College-of-Neuropsychopharmacology (ECNP), Amsterdam, Netherlands.

    Research output: Contribution to conferencePoster

  79. Published

    Time-dependent changes induced by acute stress in function and architecture of excitatory synapses in prefrontal and frontal cortex. / Popoli, M; Musazzi, L; Tornese, Paolo; Sala, N; Treccani, Giulia; Bazzini, C; Wegener, Gregers; Nyengaard, Jens Randel; Nava, Nicoletta.

    2015. Poster session presented at Neuroscience 2015, Chicago, IL, United States.

    Research output: Contribution to conferencePoster

  80. Published

    Time-dependent effects of acute stress on glutamate synapse. / Treccani, Giulia; Nava, Nicoletta; Musazzi, L; Milanese, M; Perego, C; Bonifacino, T; Bonanno, G; Popoli, M; Nyengaard, Jens Randel; Wegener, Gregers.

    2015. Poster session presented at CINP CINP Thematic Meeting on Stress, inflammation and depression: focus on novel antidepressant targets, .

    Research output: Contribution to conferencePoster

  81. Published

    Time-dependent effects of acute stress on glutamate synapse. / Treccani, Giulia; Nava, Nicoletta; Musazzi, L; Milanese, M; Perego, C; Bonifacino, T; Bonanno, G; Popoli, M; Nyengaard, Jens Randel; Wegener, Gregers.

    2015. Poster session presented at The Brain Prize Meeting 2015, Middelfart, Denmark.

    Research output: Contribution to conferencePoster

  82. Published

    Time-dependent functional changes induced by ketamine in the glutamate system: focus on glutamate release, glutamate receptors and dendritic morphology. / Treccani, Giulia; du Jardin, Kristian Gaarn; Wegener, Gregers; Müller, Heidi Kaastrup.

    2015. Poster session presented at 56th Annual Conference if the SCNP, Copenhagen, Denmark.

    Research output: Contribution to conferencePoster

  83. 2014
  84. Published

    Chronic desipramine prevents acute stress-induced reorganization of medial prefrontal cortex architecture by blocking glutamate vesicle accumulation and excitatory synapse increase. / Nava, Nicoletta; Treccani, Giulia; Liebenberg, Nico; Chen, Fenghua; Popoli, Maurizio; Wegener, Gregers; Nyengaard, Jens Randel.

    In: International Journal of Neuropsychopharmacology, 13.12.2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  85. Published

    Nitric oxide involvement in the antidepressant-like effect of ketamine in the Flinders sensitive line rat model of depression. / Liebenberg, Nico; Joca, Sâmia; Wegener, Gregers.

    In: Acta Neuropsychiatrica, 10.12.2014, p. 1-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  86. Published

    Of Pig and Man: Analogy of response to electroconvulsive therapy (ECT): most do, a few don’t. / Doudet, Doris J; Clark, C; Alstrup, Aage Kristian Olsen; Jakobsen, Steen; Gjedde, Albert; Wegener, Gregers; Videbech, Poul; Landau, Anne M.

    2014. Abstract from CINP World Congress, Vancouver, Canada.

    Research output: Contribution to conferenceConference abstract for conference

  87. Published

    Toxoplasma gondii seropositivity is positively associated with anxiety and burnout-syndrome. / Bay-Richter, C.; Buttenschon, H.; Foldager, L.; Kolstad, H.; Kaerlev, L.; Thomsen, J.; Mors, N. P. Ole; Wegener, G.

    In: International Journal of Neuropsychopharmacology, Vol. 17, 06.2014, p. 43-43.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journal

  88. Published

    Probiotic treatment alters behavior in rats on standard and high-fat diet. / Abildgaard, Anders; Lund, Sten; Hokland, Marianne; Wegener, Gregers.

    In: Acta Neuropsychiatrica, Vol. 26, No. supplement 1, 25.04.2014, p. 14.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journal

  89. Published

    Acute stress rapidly increases the readily releasable pool of glutamate vesicles in prefrontal and frontal cortex through non-genomic action of corticosterone. / Treccani, G; Musazzi, L; Perego, C; Milanese, M; Nava, N; Bonifacino, T; Lamanna, J; Malgaroli, A; Drago, F; Racagni, G; Nyengaard, J R; Wegener, G; Bonanno, G; Popoli, M.

    In: Molecular Psychiatry, Vol. 19, No. 4, 04.2014, p. 401.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  90. Published

    Stress and corticosterone increase the readily releasable pool of glutamate vesicles in synaptic terminals of prefrontal and frontal cortex. / Treccani, G; Musazzi, L; Perego, C; Milanese, M; Nava, N; Bonifacino, T; Lamanna, J; Malgaroli, A; Drago, F; Racagni, G; Nyengaard, J R; Wegener, Gregers; Bonanno, G; Popoli, M.

    In: Molecular Psychiatry, Vol. 19, 04.2014, p. 433-443.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  91. Published

    Depression and BMI influences the serum vascular endothelial growth factor level. / Elfving, Betina; Buttenschøn, Henriette N; Foldager, Leslie; Poulsen, Pia H P; Grynderup, Matias B; Hansen, Ase M; Kolstad, Henrik A; Kaerlev, Linda; Mikkelsen, Sigurd; Børglum, Anders D; Wegener, Gregers; Mors, Ole.

    In: International Journal of Neuropsychopharmacology, Vol. 17, No. 9, 17.03.2014, p. 1409-1417.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  92. Published

    Let food be thy medicine, and medicine be thy food : Hippocrates revisited. / Wegener, Gregers.

    In: Acta Neuropsychiatrica, Vol. 26, No. 1, 01.02.2014, p. 1-3.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  93. Published

    A new efficient method for synaptic vesicle quantification reveals differences between medial prefrontal cortex perforated and nonperforated synapses. / Nava, Nicoletta; Chen, Fenghua; Wegener, Gregers; Popoli, Maurizio; Nyengaard, Jens Randel.

    In: Journal of Comparative Neurology, Vol. 522, No. 2, 02.2014, p. 284-97.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  94. Published

    A serotonin-dependent mechanism is essential for the protracted antidepressant-like effect of ketamine in a rat model of depression. / du Jardin, Kristian Gaarn; Liebenberg, Nico; Müller, Heidi Kaastrup; Elfving, Betina; Sánchez, Connie; Wegener, Gregers.

    2014. Poster session presented at Society for Neuroscience 2014, Washington DC, United States.

    Research output: Contribution to conferencePoster

  95. Published

    A serotonin-dependent mechanism is essential for the sustained antidepressant-like effect of ketamine in a rat model of depression. / du Jardin, Kristian Gaarn; Liebenberg, Nico; Müller, Heidi Kaastrup; Sánchez, Connie; Wegener, Gregers.

    In: Acta Neuropsychiatrica, Vol. 26, No. S1, 2014.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journal

  96. Published

    Acute stress rapidly increases the readily releasable pool of glutamate vesicles in prefrontal and frontal cortex through corticosterone non- genomic action. / Treccani, Giulia; Musazzi, L; Perego, C; Milanese, M; Nava, Nicoletta; Bonifacino, T; Lamanna, J; Malgaroli, A; Racagni, G; Nyengaard, Jens Randel; Wegener, Gregers; Bonanno, G; Popoli, M.

    2014. Poster session presented at 9th FENS forum of neuroscience , Milan, Italy.

    Research output: Contribution to conferencePoster

  97. Published

    Acute stress rapidly increases the readily releasable pool of glutamate vesicles in prefrontal and frontal cortex through non-genomic action of corticosterone via mineralocorticoid and glucocorticoid receptors. / Treccani, Giulia; Musazzi, L; Perego, C; Milanese, M; Nava, Nicoletta; Bonifacino, T; Lamanna, J; Malgaroli, A; Racagni, G; Nyengaard, Jens Randel; Bonanno, G; Popoli, M; Wegener, Gregers.

    2014. Poster session presented at SCNP, 55th annual meeting, Copenhagen, Denmark.

    Research output: Contribution to conferencePoster

  98. Published

    Ketamine reduces evoked [3H]-D-aspartate release in the prefrontal cortex of Flinders Sensitive Line rats. / Müller, Heidi Kaastrup; Treccani, Giulia; du Jardin, Kristian Gaarn; Wegener, Gregers; Elfving, Betina.

    2014. Poster session presented at 8th International Meeting on Metabotropic Glutamate Receptors, Taormina, Sicily, Italy.

    Research output: Contribution to conferencePoster

  99. Published

    Toxoplasma gondii seropositivity is positively associated with anxiety and burnout-syndrome. / Bay-Richter, Cecilie; Buttenschøn, Henriette Nørmølle; Foldager, Leslie; Kolstad, Henrik A.; Kaerlev, Linda; Mors, Ole; Wegener, Gregers.

    2014. Abstract from CINP World Congress, Vancouver, Canada.

    Research output: Contribution to conferenceConference abstract for conference

  100. 2013
  101. Published

    Combined PET/microdialysis studies in minipig for PET tracer validation. / Landau, Anne M.; Alstrup, Aage Kristian Olsen; Wegener, Gregers; Jakobsen, Steen; Schacht, Anna C.; Jacobsen, Jan; Mørk, Arne; Sørensen, Jens Christian Hedemann; Doudet, Doris.

    2013. Abstract from Minipig Research Forum, Rom, Italy.

    Research output: Contribution to conferenceConference abstract for conference

  102. Published

    Transcranial magnetic stimulation in the FSL/FRL genetic rat model of depression. / Pedersen, Marie Louise Hesselberg; Hansen, Poul Erik Buchholtz; Wegener, Gregers.

    2013. Poster session presented at Psykiatriens 8. forskningsdag 2013, Risskov - Aarhus, Denmark.

    Research output: Contribution to conferencePoster

  103. Published

    Effects of anesthesia and species on the uptake or binding of radioligands in vivo in the Göttingen minipig. / Alstrup, Aage Kristian Olsen; Landau, Anne M.; Holden, James E; Jakobsen, Steen; Schacht, Anna C Schacht; Audrain, Hélène; Wegener, Gregers; Hansen, Axel K; Gjedde, Albert; Doudet, Doris.

    In: BioMed Research International, Vol. 2013, No. 808713, 15.07.2013, p. 1-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  104. Published

    Ketamine regulates the presynaptic release machinery in the hippocampus. / Müller, Heidi Kaastrup; Wegener, Gregers; Liebenberg, Nico; Zarate, Carlos A; Popoli, Maurizio; Elfving, Betina.

    In: Journal of Psychiatric Research, Vol. 47, No. 7, 07.2013, p. 892-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  105. Published

    The current development of CNS drug research. / Wegener, Gregers; Rujescu, Dan.

    In: International Journal of Neuropsychopharmacology, 07.05.2013, p. 1-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  106. Published

    Acta Neuropsychiatrica: A new beginning. / Wegener, Gregers.

    In: Acta Neuropsychiatrica, Vol. 25, No. 1, 01.02.2013, p. 1.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

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