Charlotte Brandt Sørensen

  1. 2018
  2. Published

    Production of genetically modified founder pigs as models for human diseases. / Callesen, Henrik; Liu, Ying; Pedersen, Hanne Skovsgaard; Sørensen, Charlotte Brandt; Bentzon, Jacob Fog.

    In: Reproduction, Fertility and Development, Vol. 30, No. 1, Abst. no. 23, 2018, p. 151.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journal

  3. 2017
  4. Published

    Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs. / Shim, Jeong; Poulsen, Christian Bo; Hagensen, Mette K; Larsen, Torben; Heegaard, Peter M H; Christoffersen, Christina; Bolund, Lars; Schmidt, Mette; Liu, Ying; Li, Juan; Li, Rong; Callesen, Henrik; Bentzon, Jacob Fog; Sørensen, Charlotte Brandt.

    In: JACC: Basic to translational science, Vol. 2, No. 5, 2017, p. 591-600.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  5. Published

    Evaluation of porcine stem cells competence for somatic cell nuclear transfer and production of cloned animals. / Secher, Jan; Liu, Ying; Petkov, Stoyan; Luo, Yonglun; Li, Dong; Hall, Vanessa Jane; Schmidt, Mette; Callesen, Henrik; Bentzon, Jacob Fog; Sørensen, Charlotte Brandt; Freude, Karla Kristine; Hyttel, Poul.

    In: Animal Reproduction Science, Vol. 178, 2017, p. 40-49.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  6. 2016
  7. Published

    Enhanced genome editing in mammalian cells with a modified dual-fluorescent surrogate system. / Zhou, Yan; Liu, Yong; Hussmann, Dianna; Brøgger, Peter; Al-Saaidi, Rasha Abdelkadhem; Tan, Shuang; Lin, Lin; Petersen, Trine Skov; Zhou, Guang Qian; Bross, Peter; Aagaard, Lars; Klein, Tino; Rønn, Sif Groth; Pedersen, Henrik Duelund; Bolund, Lars; Nielsen, Anders Lade; Sørensen, Charlotte Brandt; Luo, Yonglun.

    In: Cellular and Molecular Life Sciences, Vol. 73, No. 13, 11.01.2016, p. 2543-63.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  8. Published

    Differences in Hypercholesterolemia and Atherogenesis Induced by Common Androgen Deprivation Therapies in Male Mice. / Poulsen, Christian Bo; Mortensen, Martin Bødtker; Koechling, Wolfgang; Sørensen, Charlotte Brandt; Bentzon, Jacob Fog.

    In: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 5, No. 2, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  9. Published

    Large animal models of atherosclerosis - new tools for persistent problems in cardiovascular medicine. / Shim, Jeong; Al-Mashhadi, Rozh Husain; Sørensen, Charlotte Brandt; Bentzon, Jacob Fog.

    In: Journal of Pathology, Vol. 238, No. 2, 2016, p. 257-66.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  10. 2015
  11. Published
  12. Published

    Targeted Porcine Genome Engineering with TALENs. / Luo, Yonglun; Lin, Lin; Golas, Mariola Monika; Sørensen, Charlotte Brandt; Bolund, Lars.

    Somatic Genome Manipulation : Advances, Methods and Applications. Springer New York, 2015. p. 17-33.

    Research output: Contribution to book/anthology/report/proceedingBook chapter

  13. 2014
  14. Published

    Efficient construction of rAAV-based gene targeting vectors by Golden Gate cloning. / Luo, Yonglun; Lin, Lin; Bolund, Lars; Sørensen, Charlotte Brandt.

    In: BioTechniques, Vol. 56, No. 5, 05.2014, p. 263-8.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  15. Published

    Absence of an intron splicing silencer in porcine Smn1 intron 7 confers immunity to the exon skipping mutation in human SMN2. / Doktor, Thomas Koed; Schrøder, Lisbeth Dahl; Andersen, Henriette Skovgaard; Brøner, Sabrina; Kitewska, Anna; Sørensen, Charlotte Brandt; Andresen, Brage Storstein.

    In: PloS one, Vol. 9, No. 6, 2014, p. e98841.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  16. Published

    Efficient genome engineering using rAAV and TALENs in pigs. / Luo, Yonglun; Viuff, B M; Lin, Lin; Li, Rong; Schmidt, Mette; Rønn, S G; Pedersen, H. D.; Callesen, Henrik; Sørensen, Charlotte Brandt; Brünner, Niels; Klein, Tino; Bolund, Lars.

    In: Transgenic Research, Vol. 23, No. 1, 2014, p. 189-190.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference article

  17. 2013
  18. Published
  19. Published

    Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant. / Al-Mashhadi, Rozh H; Sørensen, Charlotte B; Kragh, Peter M; Christoffersen, Christina; Mortensen, Martin B; Tolbod, Lars P; Thim, Troels; Du, Yutao; Li, Juan; Liu, Ying; Moldt, Brian; Schmidt, Mette; Vajta, Gabor; Larsen, Torben; Purup, Stig; Bolund, Lars; Nielsen, Lars B; Callesen, Henrik; Falk, Erling; Mikkelsen, Jacob Giehm; Bentzon, Jacob F.

    In: Science Translational Medicine, Vol. 5, No. 166, 2013, p. 166ra1.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  20. 2012
  21. Published

    Genetically modified pigs for biomedical research. / Luo, Yonglun; Lin, Lin; Bolund, Lars; Jensen, Thomas G; Sørensen, Charlotte Brandt.

    In: Journal of Inherited Metabolic Disease, Vol. 35, No. 4, 2012, p. 695-713.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReview

  22. Published

    Hypercholesterolemic minipigs created by liver-specific expression of a PCSK9 gain-of-function mutant. / Bentzon, Jacob Fog; Sørensen, Charlotte Brandt; Al-Mashhadi, Rozh Husain; Kragh, Peter M; Nielsen, Lars Bo; Li, Juan; Lin, Lin; Liu, Ying; Moldt, Brian; Schmidt, Mette; Thim, Troels; Vajta, Gabor; Purup, Stig; Bolund, Lars; Callesen, Henrik; Mikkelsen, Jacob Giehm; Falk, Erling.

    In: Transgenic Research, Vol. 21, No. 4, 2012, p. 910-911.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journal

  23. Published

    Pig gene knockout by rAAV-mediated homologous recombination: comparison of BRCA1 gene knockout efficiency in Yucatan and Göttingen fibroblasts with slightly different target sequences. / Luo, Yonglun; Bolund, Lars; Sørensen, Charlotte Brandt.

    In: Transgenic Research, Vol. 21, 2012, p. 671-676.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  24. Published

    Targeted Genome Editing by Recombinant Adeno-Associated Virus (rAAV) Vectors for Generating Genetically Modified Pigs. / Luo, Yonglun; Kofod-Olsen, Emil; Christensen, Rikke; Sørensen, Charlotte Brandt; Bolund, Lars.

    In: Journal of Genetics and Genomics, Vol. 39, No. 6, 2012, p. 269-74.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReview

  25. 2011
  26. Published

    Final Report Pigs and Health 2007-2011. / Aarhus University: Department of Biomedicine & Department of Clinical Medicine; Aarhus University: Department of Molecular Biology and Genetics & Department of Animal Science; University of Copenhagen: Department of Basic Animal and Veterinary Sciences; Technical University of Denmark; LEO Pharma; Ellegaard Göttingen Minipigs A/S; Pixigene A/S; Pig Research Centre, Danish Agriculture and Food Council ; Bendixen, Christian; Callesen, Henrik; Bolund, Lars; Sørensen, Charlotte Brandt.

    Højteknologifonden, 2011. 29 p.

    Research output: Book/anthology/dissertation/reportReport

  27. Published

    An update on targeted gene repair in mammalian cells: methods and mechanisms. / Jensen, Nanna M; Dalsgaard, Trine; Jakobsen, Maria; Nielsen, Roni R; Sørensen, Charlotte B; Bolund, Lars; Jensen, Thomas G.

    In: International Journal of Biomedical Science, Vol. 18, 01.01.2011, p. 10.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReview

  28. Published

    An improved PCR strategy for fast screening of specific and random integrations in rAAV-mediated gene targeted cell clones. / Luo, Yonglun; Bolund, Lars; Sørensen, Charlotte B.

    In: BMC Research Notes, Vol. 4, 2011, p. 246.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  29. Published

    Comparison of gene expression and genome-wide DNA methylation profiling between phenotypically normal cloned pigs and conventionally bred controls. / Fei, Gao; Luo, Yonglun; Li, Shengting; Li, Jian; Lin, Lin; Nielsen, Anders Lade; Sørensen, Charlotte Brandt; Vajta, Gabor; Wang, Jun; Zhang, Xiuqing; Du, Yutao; Yang, Huanming; Bolund, Lars.

    In: P L o S One, Vol. 6, No. 10, 2011, p. e25901.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  30. Published

    High efficiency of BRCA1 knockout using rAAV-mediated gene targeting: developing a pig model for breast cancer. / Luo, Yonglun; Li, Juan; Liu, Ying; Lin, Lin; Du, Yutao; Li, Shengting; Yang, Huanming; Vajta, Gábor; Callesen, Henrik; Bolund, Lars; Sørensen, Charlotte Brandt.

    In: Transgenic Research, Vol. 20, 2011, p. 975-988.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  31. 2008
  32. Published

    High Hydrostatic Pressure Treatment of Porcine Oocytes before Handmade Cloning Improves Developmental Competence and Cryosurvival. / Du, Yutao; Lin, Lin; Schmidt, Mette; Bøgh, Ingrid B; Kragh, Peter Michael; Sørensen, Charlotte Brandt; Li, Juan; Purup, Stig; Pribenszky, Csaba; Molnár, Molnar; Kuwayama, Masaabc; Zhang, Xiuqing; Yang, Huanming; Bolund, Lars; Vajta, Gábor.

    In: Cloning and Stem Cells, Vol. 10, No. 3, 2008, p. 325-330.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  33. 2005
  34. Published

    Site-specific strand bias in gene correction using single-stranded oligonucleotides. / Sørensen, Charlotte B; Krogsdam, Anne-Margrethe; Andersen, Marie S; Kristiansen, Karsten; Bolund, Lars; Jensen, Thomas G.

    In: Journal of Molecular Medicine, Vol. 83, No. 1, 01.2005, p. 39-49.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  35. Published

    Site-specific strand bias in gene correction using single-stranded oligonucleotides. / Sørensen, Charlotte Brandt; Krogsdam, A.-M.; Andersen, M.S.; Kristiansen, K.; Bolund, Lars; Jensen, T.G.

    In: J. Mol. Med., Vol. 83, 2005, p. 39-49.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  36. 2003
  37. Published

    Functional testing of keratin 14 mutant proteins associated with the three major subtypes of epidermolysis bullosa simplex. / Sørensen, Charlotte B; Andresen, Brage S; Jensen, Uffe B; Jensen, Thomas G; Jensen, Peter K A; Gregersen, Niels; Bolund, Lars.

    In: Experimental Dermatology Online, Vol. 12, No. 4, 08.2003, p. 472-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  38. Published

    Epidermolysis bullosa simplex keratinocytes with extended lifespan established by ectopic expression of telomerase. / Jensen, Thomas G; Sørensen, Charlotte B; Jensen, Uffe B; Bolund, Lars.

    In: Experimental Dermatology Online, Vol. 12, No. 1, 02.2003, p. 71-7.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  39. Published

    Epidermolysis bullosa simplex keratinocytes with extended lifespan established by ectopic expression of telomerase. / Jensen, T.G.; Sørensen, C.B.; Jensen, U.B.; Bolund, L.

    In: Exp. Dermatol., Vol. 12, 2003, p. 71-77.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  40. Published

    Functional testing of keratin 14 mutant proteins associated with the three major subtypes of epidermolysis bullosa simplex. / Sørensen, C.B.; Andresen, B.S.; Jensen, U.B.; Jensen, T.G.; Jensen, P.K.A.J.; Gregersen, N.; Bolund, L.

    In: Exp. Dermatol., Vol. 12, 2003, p. 472-479.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  41. 2002
  42. Published

    Mechanisms underlying targeted gene correction using chimeric RNA/DNA and single-stranded DNA oligonucleotides. / Andersen, Marie S; Sørensen, Charlotte B; Bolund, Lars; Jensen, Thomas G.

    In: Journal of Molecular Medicine, Vol. 80, No. 12, 12.2002, p. 770-81.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  43. Published

    Mechanisms underlying targeted gene correction using chimeric RNA/DNA and single-stranded DNA oligonucleotides. / Andersen, M.S.; Sørensen, C.B.; Bolund, L.; Jensen, T.G.

    In: J. Mol. Med., Vol. 80, 2002, p. 770-781.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReview

  44. 2001
  45. Published
  46. 2000
  47. Published

    Epidermolysis bullosa simplex: Korrelation mellem genotype og fænotype hos danske patienter. / Sørensen, C.B.; Ladekjær-Mikkelsen, A.-S.; Andresen, B.S.; Brandrup, F.; Veien, N.K.; Buus, S.K.; Anton-Lamprecht, I.; Kruse, T.; Jensen, P.K.A.; Eiberg, H.; Bolund, L.; Gregersen, N.

    In: Ugeskrift for Laeger, Vol. 162, 2000, p. 1873-1876.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  48. Published

    Keratinsygdomme : Oversigtsartikel. / Jensen, P.K.A.; Sørensen, C.B.; Andresen, B.S.; Brandrup, F.; Veien, N.K.; Buus, S.K.; Gregersen, N.; Bolund, L.

    In: Ugeskrift for Laeger, Vol. 162, 2000, p. 1867-1872.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReview

  49. 1999
  50. Published

    Identification of novel and known mutations in the genes for keratin 5 and 14 in Danish patients with epidermolysis bullosa simplex: Correlation between genotype and phenotype. / Sørensen, C.B.; Ladekjær-Mikkelsen, A.-S.; Andresen, B.S.; Brandrup, F.; Veien, N.K.; Buus, S.K.; Anton-Lamprecht, I.; Kruse, T.A.; Jensen, P.K.A.; Eiberg, H.; Bolund, L.; Gregersen, N.

    In: J. Invest. Dermatol., Vol. 112, 1999, p. 184-190.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  51. 1997
  52. Published

    Cloning of the murine tetranectin gene and 5'-flanking region. / Sørensen, Charlotte Brandt; Berglund, Lars; Petersen, Torben Ellebæk.

    In: Gene, Vol. 201, No. 1-2, 12.11.1997, p. 199-202.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  53. 1995
  54. Published

    Cloning of a cDNA encoding murine tetranectin. / Sørensen, Charlotte Brandt; Berglund, Lars; Petersen, Torben Ellebæk.

    In: Gene, Vol. 152, No. 2, 23.01.1995, p. 243-5.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article

  55. 1993
  56. Published

    Determination of the disulphide bridge arrangement of bovine histidine-rich glycoprotein. / Sørensen, Charlotte Brandt; Krogh-Pedersen, H; Petersen, T E.

    In: F E B S Letters, Vol. 328, No. 3, 08.1993, p. 285-90.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal article