Alexander N. Zelikin

  1. 2017
  2. E-pub ahead of print

    Macromolecular Antiviral Agents against Zika, Ebola, SARS, and Other Pathogenic Viruses. / Schandock, Franziska; Riber, Camilla Frich; Röcker, Annika; Müller, Janis A; Harms, Mirja; Gajda, Paulina; Zuwala, Kaja; Andersen, Anna H F; Løvschall, Kaja Borup; Tolstrup, Martin; Kreppel, Florian; Münch, Jan; Zelikin, Alexander N.

    In: Advanced Healthcare Materials, 25.09.2017.

    Research output: Research - peer-reviewJournal article

  3. Published

    Enzyme Prodrug Therapy Engineered into Electrospun Fibers with Embedded Liposomes for Controlled, Localized Synthesis of Therapeutics. / Chandrawati, Rona; Olesen, Morten T. J.; Marini, Thatiane C. C.; Bisra, Gurpal; Guex, Anne Geraldine; de Oliveira, Marcelo G.; Zelikin, Alexander N.; Stevens, Molly M.

    In: Advanced Healthcare Materials, Vol. 6, No. 17, 1700385, 06.09.2017.

    Research output: Research - peer-reviewJournal article

  4. Published

    Synthetic Polymer with a Structure-Driven Hepatic Deposition and Curative Pharmacological Activity in Hepatic Cells. / Riber, Camilla Frich; Halling Folkmar Andersen, Anna; Anegaard Rolskov, Lærke ; Zuwala, Kaja; Gajda, Paulina; Borup Løvschall, Kaja; Dagnæs-Hansen, Frederik; Banda, Dominic H.; Pietschmann, Thomas; Tolstrup, Martin; Zelikin, Alexander N.

    In: ACS Macro Letters, Vol. 6, No. 935-940, 15.08.2017, p. 935-940.

    Research output: Research - peer-reviewJournal article

  5. Published

    Preparation, single-molecule manipulation and energy transfer investigation of a polyfluorene-graft-DNA polymer. / Madsen, Mikael; Christensen , Rasmus S. ; Krissanaprasit, Abhichart; Bakke, Mette Riis; Riber, Camilla Frich; Nielsen , Karina S. ; Zelikin, Alexander N.; Gothelf, Kurt Vesterager.

    In: Chemistry: A European Journal, Vol. 23, No. 44, 22.06.2017.

    Research output: Research - peer-reviewJournal article

  6. Published

    Recent advances in macromolecular prodrugs. / Riber, Camilla Frich; Zelikin, Alexander N.

    In: Current Opinion in Colloid & Interface Science, Vol. 31, 21.06.2017.

    Research output: Research - peer-reviewReview

  7. Published

    Localized and Controlled Delivery of Nitric Oxide to the Conventional Outflow Pathway via Enzyme Biocatalysis : Toward Therapy for Glaucoma. / Chandrawati, Rona; Chang, Jason Y. H.; Reina-Torres, Ester; Jumeaux, Coline; Sherwood, Joseph M.; Stamer, W. Daniel; Zelikin, Alexander N.; Overby, Darryl R.; Stevens, Molly M.

    In: Advanced Materials, Vol. 29, No. 16, 1604932, 25.04.2017.

    Research output: Research - peer-reviewJournal article

  8. Published

    Macromolecular Prodrugs of Ribavirin : Structure-Function Correlation as Inhibitors of Influenza Infectivity. / Riber, Camilla Frich; Hinton, Tracey M; Gajda, Paulina; Zuwala, Kaja; Tolstrup, Martin; Stewart, Cameron; Zelikin, Alexander N.

    In: Molecular Pharmaceutics, Vol. 14, No. 1, 03.01.2017, p. 234-241.

    Research output: Research - peer-reviewJournal article

  9. 2016
  10. Published

    Albumin–Polymer–Drug Conjugates: Long Circulating, High Payload Drug Delivery Vehicles. / Smith, Anton Allen Abbotsford; Zuwala, Kaja; Pilgram, Oliver; Johansen, Karen Singers Eiskjær; Tolstrup, Martin; Dagnæs-Hansen, Frederik; Zelikin, Alexander N.

    In: ACS Macro Letters, Vol. 5, 15.09.2016, p. 1089-1094.

    Research output: Research - peer-reviewJournal article

  11. Published

    Poly(vinyl alcohol) Physical Hydrogels : Matrix-Mediated Drug Delivery Using Spontaneously Eroding Substrate. / Jensen, Bettina E. B.; Davila, Izaskun; Zelikin, Alexander N.

    In: Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, Vol. 120, No. 26, 07.07.2016, p. 5916-5926.

    Research output: Research - peer-reviewJournal article

  12. Published

    Triple Activity of Lamivudine Releasing Sulfonated Polymers against HIV-1. / Danial, Maarten; Halling Folkmar Andersen, Anna; Zuwala, Kaja; Cosson, Steffen; Riber, Camilla Frith; Smith, Anton A. A.; Tolstrup, Martin; Moad, Graeme; Zelikin, Alexander N.; Postma, Almar.

    In: Molecular Pharmaceutics, Vol. 13, No. 7, 07.2016, p. 2397-2410.

    Research output: Research - peer-reviewJournal article

  13. Published
  14. Published

    Materials and methods for delivery of biological drugs. / Zelikin, Alexander N.; Ehrhardt, Carsten; Healy, Anne Marie.

    In: Nature Chemistry, Vol. 8, No. 11, 2016, p. 997-1007.

    Research output: Research - peer-reviewJournal article

  15. Published

    Polyanionic Macromolecular Prodrugs of Ribavirin : Antiviral Agents with a Broad Spectrum of Activity. / Hinton, Tracey M.; Zuwala, Kaja; Deffrasnes, Celine; Todd, Shawn; Shi, Shuning; Marsh, Glenn A.; Dearnley, Megan; Wohl, Benjamin M.; Tolstrup, Martin; Zelikin, Alexander N.

    In: Advanced Healthcare Materials, Vol. 5, No. 5, 2016, p. 534-540.

    Research output: Research - peer-reviewJournal article

  16. Published

    Tools of gene transfer applied to the intracellular delivery of non-nucleic acid polyanionic drugs. / Kryger, Mille B. L.; Pedersen, Søren L.; Wohl, Benjamin M.; Zelikin, Alexander N.

    In: Chemical Communications, Vol. 52, No. 5, 2016, p. 889-891.

    Research output: Research - peer-reviewJournal article

  17. 2015
  18. Published

    Routing of individual polymers in designed patterns. / Knudsen, Jakob Bach; Liu, Lei; Kodal, Anne Louise Bank; Madsen, Mikael; Li, Qiang; Song, Jie; Woehrstein, Johannes; Wickham, Shelley; Strauss, Maximillian; Schueder, Florian; Vinther, Jesper; Krissanaprasit, Abhichart; Gudnason, Daniel Aron; Smith, Anton Allen Abbotsford; Ogaki, Ryosuke; Zelikin, Alexander N.; Besenbacher, Flemming; Birkedal, Victoria; Yin, Peng; Shih, William M.; Jungmann, Ralf; Dong, Mingdong; Gothelf, Kurt Vesterager.

    In: Nature Nanotechnology, Vol. 10, 31.08.2015, p. 892-898.

    Research output: Research - peer-reviewJournal article

  19. Published

    Self-Immolative Linkers Literally Bridge Disulfide Chemistry and the Realm of Thiol-Free Drugs. / Riber, Camilla Frich; Smith, Anton A. A.; Zelikin, Alexander N.

    In: Advanced Healthcare Materials, Vol. 4, No. 12, 26.08.2015, p. 1887-1890.

    Research output: Research - peer-reviewJournal article

  20. Published

    Micro-structured, spontaneously eroding hydrogels accelerate endothelialization through presentation of conjugated growth factors. / Jensen, Bettina E. B.; Edlund, Katrine; Zelikin, Alexander N.

    In: Biomaterials, Vol. 49, 05.2015, p. 113-124.

    Research output: Research - peer-reviewJournal article

  21. Published

    Highly active macromolecular prodrugs inhibit expression of the hepatitis c virus genome in the host cells. / Ruiz-Sanchis, Pau; Wohl, Benjamin M.; Smith, Anton A A; Zuwala, Kaja; Melchjorsen, Jesper; Tolstrup, Martin; Zelikin, Alexander N.

    In: Advanced Healthcare Materials, Vol. 4, No. 1, 01.01.2015, p. 65-68.

    Research output: Research - peer-reviewJournal article

  22. Published

    Macromolecular prodrugs of ribavirin : towards a treatment for co-infection with HIV and HCV. / Smith, Anton Allen Abbotsford; Zuwala, Kaja; Kryger, Mille; Wohl, Benjamin; Guerrero-Sanchez, Carlos; Tolstrup, Martin; Postma, Almar; Zelikin, Alexander N.

    In: Chemical Science, Vol. 6, No. 1, 2015, p. 264-269.

    Research output: Research - peer-reviewJournal article

  23. Published

    Phospholipid-polymer amphiphile hybrid assemblies and their interaction with macrophages. / Panneerselvam, Karthiga; Lynge, Martin E.; Riber, Camilla Frich; Mena-Hernando, Sofia; Smith, Anton A. A.; Goldie, Kenneth N.; Zelikin, Alexander N.; Stadler, Brigitte.

    In: Biomicrofluidics, Vol. 9, No. 5, 052610, 2015.

    Research output: Research - peer-reviewJournal article

  24. Published

    Polymers Fight HIV : Potent (Pro)Drugs Identified Through Parallel Automated Synthesis. / Zuwala, Kaja; Smith, Anton A A; Postma, Almar; Guerrero-Sanchez, Carlos; Ruiz Sanchis, Pau; Melchjorsen, Jesper; Tolstrup, Martin; Zelikin, Alexander N.

    In: Advanced Healthcare Materials, Vol. 4, No. 1, 2015, p. 46-50.

    Research output: Research - peer-reviewJournal article

  25. 2014
  26. Published

    Disulfide reshuffling triggers the release of a thiol-free anti-HIV agent to make up fast-acting, potent macromolecular prodrugs. / Kock, Anders; Zuwala, Kaja; Smith, Anton A A; Ruiz-Sanchis, Pau; Wohl, Benjamin M; Tolstrup, Martin; Zelikin, Alexander N.

    In: Chemical Communications, Vol. 50, No. 93, 04.12.2014, p. 14498-500.

    Research output: Research - peer-reviewJournal article

  27. Published

    Enzyme prodrug therapy engineered into biomaterials. / Mendes, Ana C.; Zelikin, Alexander N.

    In: Advanced Functional Materials, Vol. 24, No. 33, 03.09.2014, p. 5202-5210.

    Research output: Research - peer-reviewJournal article

  28. Published

    Biocatalytic polymer thin films : optimization of the multilayered architecture towards in situ synthesis of anti-proliferative drugs. / Andreasen, Sidsel Ø; Fejerskov, Betina; Zelikin, Alexander N.

    In: Nanoscale, Vol. 6, No. 8, 21.04.2014, p. 4131-40.

    Research output: Research - peer-reviewJournal article

  29. Published

    Biocatalytic polymer coatings : on-demand drug synthesis and localized therapeutic effect under dynamic cell culture conditions. / Fejerskov, Betina; Jensen, Najah B S; Mian Teo, Boon; Stadler, Brigitte Maria; Zelikin, Alexander N.

    In: Small, Vol. 10, No. 7, 09.04.2014, p. 1314-24.

    Research output: Research - peer-reviewJournal article

  30. Published

    Macromolecular Prodrugs of Ribavirin: Concerted Efforts of the Carrier and the Drug. / Smith, Anton A A; Wohl, Benjamin M; Kryger, Mille B L; Hedemann, Natasha; Guerrero-Sanchez, Carlos; Postma, Almar; Zelikin, Alexander N.

    In: Advanced Healthcare Materials, Vol. 3, No. 9, 10.01.2014, p. 1404-1407.

    Research output: Research - peer-reviewJournal article

  31. Published

    Macromolecular Prodrugs for Controlled Delivery of Ribavirin. / Kryger, Mille B L; Smith, Anton A A; Wohl, Benjamin M; Zelikin, Alexander N.

    In: Macromolecular Bioscience, Vol. 14, No. 2, 2014, p. 173-185.

    Research output: Research - peer-reviewJournal article

  32. Published

    Macromolecular (pro)Drugs in antiviral research. / Smith, Anton Allen Abbotsford; Kryger, Mille; Wohl, Benjamin; Ruiz Sanchis, Pau; Zuwala, Kaja; Tolstrup, Martin; Zelikin, Alexander N.

    In: Polymer Chemistry, Vol. 5, No. 22, 2014, p. 6407-6425.

    Research output: Research - peer-reviewJournal article

  33. Published

    Macromolecular (pro)drugs with concurrent direct activity against the hepatitis C virus and inflammation. / Wohl, Benjamin; Smith, Anton Allen Abbotsford; Jensen, Bettina Elisabeth Brøgger; Zelikin, Alexander N.

    In: Journal of Controlled Release, Vol. 196, 2014, p. 197–207.

    Research output: Research - peer-reviewJournal article

  34. 2013
  35. Published

    Cholesterol Modification of (Bio)Polymers Using UV-Vis Traceable Chemistry in Aqueous Solutions. / Rasmussen, Kasper F; Smith, Anton A A; Ruiz-Sanchis, Pau; Edlund, Katrine; Zelikin, Alexander N.

    In: Macromolecular Bioscience, Vol. 14, No. 1, 17.09.2013, p. 33-44.

    Research output: Research - peer-reviewJournal article

  36. Published

    Poly(vinyl alcohol) Physical Hydrogel Nanoparticles, Not Polymer Solutions, Exert Inhibition of Nitric Oxide Synthesis in Cultured Macrophages. / Andreasen, Sidsel Østerby; Chong, Siow Feng; Wohl, Benjamin M; Goldie, Kenneth N; Zelikin, Alexander N.

    In: Biomacromolecules, Vol. 14, 22.04.2013, p. 1687-1695.

    Research output: Research - peer-reviewJournal article

  37. Published

    Macromolecular prodrugs of ribavirin combat side effects and toxicity with no loss of activity of the drug. / Kryger, M.B.L.; Wohl, B.M.; Smith, A.A.A.; Zelikin, Alexander N.

    In: Chemical Communications, Vol. 49, No. 26, 04.04.2013, p. 2643-2645.

    Research output: Research - peer-reviewJournal article

  38. Published

    Bioresorbable Surface-Adhered Enzymatic Microreactors Based on Physical Hydrogels of Poly(vinyl alcohol). / Fejerskov, Betina; Smith, Anton A A; Jensen, Bettina E B; Hussmann, Thomas; Zelikin, Alexander N.

    In: Langmuir, Vol. 29, No. 1, 2013, p. 344-54.

    Research output: Research - peer-reviewJournal article

  39. Published

    Lipogels: Surface-Adherent Composite Hydrogels Assembled from Poly(Vinyl Alcohol) and Liposomes. / Jensen, Bettina Elisabeth Brøgger; Rigau, Leticia Hosta; Spycher, Philipp; Reimhult, Erik; Stadler, Brigitte Maria; Zelikin, Alexander N.

    In: Nanoscale, Vol. 5, No. 15, 2013, p. 6758-6766.

    Research output: Research - peer-reviewJournal article

  40. Published

    Liposomal Templating, Association with Mammalian Cells, and Cytotoxicity of Poly(vinyl alcohol) Physical Hydrogel Nanoparticles. / Andreasen, Sidsel Østerby; Chong, Siow Feng; Kryger, Mille; Jensen, Bettina Elisabeth Brøgger; Postma, Almar; Alves, Marie-Helene; Stadler, Brigitte Maria; Goldie, Kenneth; Zelikin, Alexander N.

    In: Particle & Particle Systems Characterization, Vol. 30, No. 6, 2013, p. 514-522.

    Research output: Research - peer-reviewJournal article

  41. Published

    Liposomes as Drug Deposits in Mulitlayered Polymer Films. / Madsen, Martin Elias Lynge; Laursen, Marie Bækgaard; Rigau, Leticia Hosta; Jensen, Bettina Elisabeth Brøgger; Ogaki, Ryosuke; Smith, Anton Allen Abbotsford; Zelikin, Alexander N.; Stadler, Brigitte Maria.

    In: A C S Applied Materials and Interfaces, Vol. 5, No. 8, 2013, p. 2967-2975.

    Research output: Research - peer-reviewJournal article

  42. Published

    Microstructured, Functional PVA Hydrogels through Bioconjugation with Oligopeptides under Physiological Conditions. / Chong, Siow Feng; Smith, Anton A A; Zelikin, Alexander N.

    In: Small, Vol. 9, No. 6, 2013, p. 942-950.

    Research output: Research - peer-reviewJournal article

  43. Published

    Narrow Therapeutic Window of Ribavirin as an Inhibitor of Nitric Oxide Synthesis is Broadened by Macromolecular Prodrugs. / Wohl, Benjamin M; Smith, Anton Allen Abbotsford; Kryger, Mille B L; Zelikin, Alexander N.

    In: Biomacromolecules, Vol. 14, No. 11, 2013, p. 3916-26.

    Research output: Research - peer-reviewJournal article

  44. Published

    Surface Grafted Glycopolymer Brushes to Enhance Selective Adhesion of HepG2 Cells. / Chernyy, Sergey; Jensen, Bettina Elisabeth Brøgger; Shimizu, Kyoko; Ceccato, Marcel; Pedersen, Steen Uttrup; Zelikin, Alexander N.; Daasbjerg, Kim; Iruthayaraj, Joseph.

    In: Journal of Colloid and Interface Science, Vol. 404, 2013, p. 207–214.

    Research output: Research - peer-reviewJournal article

  45. 2012
  46. Published

    Intelligent Polymer Thin Films and Coatings for Drug Delivery. / Zelikin, Alexander N.; Stadler, Brigitte Maria.

    Intelligent Surfaces in Biotechnology - Scientific and engineering concepts, enabling technologies, and translation to bio-oriented applications. ed. / H. Michelle Grandin; Marcus Textor. John Wiley & Sons Ltd, 2012.

    Research output: Research - peer-reviewBook chapter

  47. Published

    Macromolecular design of poly(vinyl alcohol) by RAFT polymerization. / Smith, A.A.A.; Hussmann, Thomas; Elich, Joseph; Alves, Marie-Helene; Postma, A.; Zelikin, Alexander N.

    In: Polymer Chemistry, Vol. 3, No. 1, 01.01.2012, p. 85-88.

    Research output: Research - peer-reviewJournal article

  48. Published

    Biodistribution of polymer hydrogel capsules for the delivery of therapeutics. / Hinton, Tracey M; Monaghan, Paul; Green, Diane; Kooijmans, Sander A A; Shi, Shuning; Breheney, Kerry; Tizard, Mark; Nicolazzo, Joseph A; Zelikin, Alexander N.; Wark, Kim.

    In: Acta Biomaterialia, Vol. 8, No. 9, 2012, p. 3251-60.

    Research output: Research - peer-reviewJournal article

  49. Published

    Engineering surface adhered poly(vinyl alcohol) physical hydrogels as enzymatic microreactors. / Fejerskov, Betina; Jensen, Bettina E B; Jensen, Najah Brok Søndervang; Chong, Siow Feng; Zelikin, Alexander N.

    In: A C S Applied Materials and Interfaces, Vol. 4, No. 9, 2012, p. 4981-90.

    Research output: Research - peer-reviewJournal article

  50. Published

    Macromolecule Functionalization of Disulfide-Bonded Polymer Hydrogel Capsules and Cancer Cell Targeting. / Shimoni, Olga; Postma, Almar; Yan, Yan; Scott, Andrew M.; Heath, Joan K.; Nice, Edouard C.; Zelikin, Alexander N.; Caruso, Frank.

    In: A C S Nano, Vol. 6, No. 2, 2012, p. 1463-1472.

    Research output: Research - peer-reviewJournal article

  51. Published

    Substrate mediated enzyme prodrug therapy. / Fejerskov, Betina; Zelikin, Alexander N.

    In: P L o S One, Vol. 7, No. 11, 2012, p. e49619.

    Research output: Research - peer-reviewJournal article

  52. Published

    Surface adhered poly(vinyl alcohol) physical hydrogels as tools for rational design of intelligent biointerfaces. / Jensen, Bettina Elisabeth Brøgger; Alves, Marie-Helene ; Fejerskov, Betina; Stadler, Brigitte; Zelikin, Alexander N.

    In: Soft Matter, Vol. 8, 2012, p. 4625-4634.

    Research output: Research - peer-reviewJournal article

  53. Published

    Surface-Adhered Composite Poly(Vinyl Alcohol) Physical Hydrogels: Polymersome-Aided Delivery of Therapeutic Small Molecules. / Rigau, Leticia Hosta; Jensen, Bettina Elisabeth Brøgger; Fjeldsø, Kit; Postma, Almar; Li; Goldie; Albericio, ; Zelikin, Alexander N.; Stadler, Brigitte Maria.

    In: Advanced Healthcare Materials, 2012.

    Research output: Research - peer-reviewJournal article

  54. 2011
  55. Published

    A Critical Look at multilayered Polymer Capsules in Biomedicine: Drug Carriers, Artificial organelles, and Cell Mimic. / Stadler, Brigitte; Price, Andrew D.; Zelikin, Alexander N.

    In: Advanced Functional Materials, Vol. 21, No. 1, 07.01.2011, p. 14-28.

    Research output: Research - peer-reviewJournal article

  56. Published

    Degradation of liposomal subcompartments in PEGylated capsosomes. / Chandrawati, R.; Chong, S.-F.; Zelikin, Alexander N.; Rigau, Leticia Hosta; Stadler, Brigitte; Caruso, F.

    In: Soft Matter, Vol. 8, 2011, p. 9638-9646.

    Research output: Research - peer-reviewJournal article

  57. Published

    Exploiting Fluorescent Polymers To Probe the Self-Assembly of Virus-like Particles. / Caden-Nava, Ruben D.; Hu, Yufang; Garmann, Rees F.; Ng, Benny; Zelikin, Alexander N.; Knobler, Charles M.; Gelbart, William M.

    In: Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, Vol. 115, 2011, p. 2386-2391.

    Research output: Research - peer-reviewJournal article

  58. Published

    Poly(vinyl alcohol) physical hydrogels : New vista on a long serving biomaterial. / Alves, M.-H.; Jensen, Bettina Elisabeth Brøgger; Smith, Anton Allen Abbotsford; Zelikin, Alexander N.

    In: Macromolecular Bioscience, Vol. 11, 2011, p. 1293-1313.

    Research output: Research - peer-reviewJournal article

  59. Published

    Poly(vinyl alcohol) Physical Hydrogels: Non-cryogenic Stabilization Allows Nano- and Micro-Scale Materials Design. / Jensen, Bettina Elisabeth Brøgger; Smith, Anton Allen Abbotsford; Fejerskov, Betina; Postma, Almar; Senn, Philipp; Reimhult, Erik; Pla-Roca, Mateu; Isa, Lucio; Sutherland, Duncan S; Stadler, Brigitte; Zelikin, Alexander N.

    In: Langmuir, Vol. 27, No. 16, 2011, p. 10216–10223.

    Research output: Research - peer-reviewJournal article

  60. Published

    Redox-Active Polymer Microcapsules for the Delivery of a Survivin-Specific siRNA in Prostate Cancer Cells. / Becker, A. L.; Orlotti, N. I. ; Folini, M.; Cavalieri, F.; Zelikin, Alexander N.; Johnston, A. P. R. J.; Zaffaroni, N.; Caruso, F.

    In: ACS Nano, Vol. 5, 2011, p. 1335-1344.

    Research output: Research - peer-reviewJournal article

  61. Published

    Tuning the Permeability of Polymer Hydrogel Capsules: An Investigation of Cross-Linking Density, Membrane Thickness, and Cross-Linkers. / Chong, S.-F.; Zelikin, Alexander N.; Lee, J. H.; Caruso, F.

    In: Langmuir, Vol. 27, 2011, p. 1724-1730.

    Research output: Research - peer-reviewJournal article

  62. 2010
  63. Published

    Drug Releasing Polymer Thin Films: New Era of Surface-Mediated Drug Delivery. / Zelikin, Alexander N.

    In: A C S Nano, Vol. 4, No. 5, 2010, p. 2494-2509.

    Research output: ResearchReview

  64. Published