1. 2016
  2. Published

    SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization. / Damas, Nkerorema Djodji; Marcatti, Michela; Côme, Christophe; Christensen, Lise Lotte; Nielsen, Morten Muhlig; Baumgartner, Roland; Gylling, Helene Maria; Maglieri, Giulia; Rundsten, Carsten Friis; Seemann, Stefan E; Rapin, Nicolas; Thézenas, Simon; Vang, Søren; Ørntoft, Torben; Andersen, Claus Lindbjerg; Pedersen, Jakob Skou; Lund, Anders H.

    In: Nature Communications, Vol. 7, 22.12.2016, p. 13875.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  3. Published

    Incidence, prevalence, diagnostic delay, and clinical presentation of female 46,XY disorders of sex development. / Berglund, Agnethe; Johannsen, Trine H; Krag, Kirstine Stochholm; Viuff, Mette H; Fedder, Jens; Main, Katharina M; Gravholt, Claus H.

    In: Endocrinology, Vol. 101, No. 12, 01.12.2016, p. 4532-4540.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  4. Published

    HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer. / Ross-Adams, Helen; Ball, Stephen J.; Lawrenson, Kate; Halim, Silvia; Russell, Roslin; Wells, Claire; Strand, Siri; Ørntoft, Torben F; Larson, Melissa C; Armasu, Sebastian M; Massie, Charles E; Asim, Mohammad; Mortensen, Martin M; Borre, Michael; Woodfine, Kathryn; Warren, Anne Y; Lamb, Alastair D; Kay, Jonathan; Whitaker, Hayley; Ramos-Montoya, Antonio; Murrell, Adele; Sørensen, Karina D; Fridley, Brooke L; Goode, Ellen L; Gayther, Simon A; Masters, John R; Neal, David E; Mills, Ian G.

    In: OncoTarget, Vol. 7, No. 46, 15.11.2016, p. 74734-74746.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  5. Published

    Multi-nucleotide de novo Mutations in Humans. / Besenbacher, Søren; Sulem, Patrick; Helgason, Agnar; Helgason, Hannes; Kristjansson, Helgi; Jonasdottir, Aslaug; Jonasdottir, Adalbjorg; Magnusson, Olafur Th; Thorsteinsdottir, Unnur; Masson, Gisli; Kong, Augustine; Gudbjartsson, Daniel F; Stefansson, Kari.

    In: P L o S Genetics, Vol. 12, No. 11, e1006315, 11.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  6. Published

    Spatial and temporal clonal evolution during development of metastatic urothelial carcinoma. / Thomsen, Mathilde B H; Nordentoft, Iver; Lamy, Philippe; Høyer, Søren; Vang, Søren; Hedegaard, Jakob; Borre, Michael; Jensen, Jørgen B; Ørntoft, Torben F; Dyrskjøt, Lars.

    In: Molecular Oncology, Vol. 10, No. 9, 11.2016, p. 1450-1460.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  7. Published

    Paired exome analysis reveals clonal evolution and potential therapeutic targets in urothelial carcinoma. / Lamy, Philippe; Nordentoft, Iver Kristiansen; Birkenkamp-Demtröder, Karin; Thomsen, Mathilde Borg Houlberg; Villesen, Palle; Vang, Søren; Hedegaard, Jakob; Borre, Michael; Jensen, Jørgen Bjerggaard; Ørntoft, Torben Falck; Andersen, Lars Dyrskjøt.

    In: Cancer Research, 01.10.2016, p. 5894-5906.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  8. Published

    Prevalence of the HOXB13 G84E mutation in Danish men treated by radical prostatectomy and correlations with prostate cancer risk and aggressiveness. / Storebjerg, Tine Maj; Høyer, Søren; Kirkegaard, Pia; Bro, Flemming; Lu Camp ; Orntoft, Torben Falck; Borre, Michael; Sørensen, Karina Dalsgaard.

    In: B J U International (Online), Vol. 118, No. 4, 01.10.2016, p. 646-653.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  9. Published

    Widespread DNA hypomethylation and differential gene expression in Turner syndrome. / Trolle, Christian; Nielsen, Morten Muhlig; Skakkebæk, Anne; Lamy, Philippe; Vang, Søren; Hedegaard, Jakob; Nordentoft, Iver; Ørntoft, Torben Falck; Pedersen, Jakob Skou; Gravholt, Claus Højbjerg.

    In: Scientific Reports, Vol. 6, 34220, 01.10.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  10. Published

    Growth Hormone and Insulin Signaling in Acromegaly: Impact of Surgery versus Somatostatin Analog Treatment. / Dal, Jakob; Lundby Høyer, Katrine; Pedersen, Steen Bønløkke; Erik Magnusson, Nils; Bjerring, Peter; Frystyk, Jan; Møller, Niels; Jessen, Niels; Otto Lunde Jørgensen, Jens.

    In: Endocrinology, Vol. 101, No. 10, 10.2016, p. 3716-3723.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  11. Published

    Erythropoietin does not activate erythropoietin receptor signaling or lipolytic pathways in human subcutaneous white adipose tissue in vivo. / Christensen, Britt; Nellemann, Birgitte; Jørgensen, Jens Otto Lunde; Pedersen, Steen B; Jessen, Niels.

    In: Lipids in Health and Disease, Vol. 15, No. 1, 160, 17.09.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  12. Published

    Fast, accurate and automatic ancient nucleosome and methylation maps with epiPALEOMIX. / Hanghøj, Kristian; Seguin, Andaine; Schubert, Mikkel; Madsen, Tobias; Pedersen, Jakob Skou; Willerslev, Eske; Orlando, Ludovic.

    In: Molecular Biology and Evolution, Vol. 33, No. 12, 13.09.2016, p. 3284-3298.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  13. Published

    A 6-year Follow-up survey of health status in middle-aged women with Turner syndrome. / Fjermestad, Krister W; Naess, Eva E; Bahr, David; Gravholt, Claus H.

    In: Clinical Endocrinology, Vol. 85, No. 3, 09.2016, p. 423-9.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  14. Published

    miRNA profiling of circulating EpCAM(+) extracellular vesicles: promising biomarkers of colorectal cancer. / Ostenfeld, Marie Stampe; Jensen, Steffen Grann; Jeppesen, Dennis Kjølhede; Christensen, Lise-Lotte; Thorsen, Stine Buch; Stenvang, Jan; Hvam, Michael Lykke; Thomsen, Anni Rønfeldt; Mouritzen, Peter; Rasmussen, Mads Heilskov; Nielsen, Hans Jørgen; Ørntoft, Torben Falck; Andersen, Claus Lindbjerg.

    In: Journal of Extracellular Vesicles, Vol. 5, 29.08.2016, p. 31488.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  15. Published

    Recombinase-Mediated Cassette Exchange (RMCE)-in Reporter Cell Lines as an Alternative to the Flp-in System. / Callesen, Morten M; Berthelsen, Martin F; Lund, Sira; Füchtbauer, Annette C; Füchtbauer, Ernst-Martin; Jakobsen, Jannik E.

    In: PLOS ONE, Vol. 11, No. 8, e0161471, 19.08.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  16. Published

    miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells. / Rasmussen, Mads Heilskov; Lyskjær, Iben; Jersie-Christensen, Rosa Rakownikow; Tarpgaard, Line Schmidt; Primdal-Bengtson, Bjarke; Nielsen, Morten Muhlig; Pedersen, Jakob Skou; Hansen, Tine Plato; Hansen, Flemming; Olsen, Jesper Velgaard; Pfeiffer, Per; Ørntoft, Torben Falck; Andersen, Claus Lindbjerg.

    In: Nature Communications, Vol. 7, 16.08.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  17. Published

    The Potential of MicroRNAs as Prostate Cancer Biomarkers. / Fabris, Linda; Ceder, Yvonne; Chinnaiyan, Arul M; Jenster, Guido W; Sorensen, Karina D; Tomlins, Scott; Visakorpi, Tapio; Calin, George A.

    In: European Urology, Vol. 70, No. 2, 21, 01.08.2016, p. 312-322.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  18. Published

    Long-term Cognitive Implications of Intrauterine Hyperglycemia in Adolescent Offspring of Women With Type 1 Diabetes (the EPICOM Study). / Bytoft, Birgitte; Knorr, Sine; Vlachova, Zuzana; Jensen, Rikke B; Mathiesen, Elisabeth R; Beck-Nielsen, Henning; Gravholt, Claus H; Jensen, Dorte M; Clausen, Tine D; Mortensen, Erik L; Damm, Peter.

    In: Diabetes Care, Vol. 39, No. 8, 08.2016, p. 1356-63.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  19. Published

    Comprehensive Transcriptional Analysis of Early-Stage Urothelial Carcinoma. / Hedegaard, Jakob; Lamy, Philippe; Nordentoft, Iver; Algaba, Ferran; Høyer, Søren; Ulhøi, Benedicte Parm; Vang, Søren; Reinert, Thomas; Hermann, Gregers G; Mogensen, Karin; Thomsen, Mathilde Borg Houlberg; Nielsen, Morten Muhlig; Marquez, Mirari; Segersten, Ulrika; Aine, Mattias; Höglund, Mattias; Birkenkamp-Demtröder, Karin; Fristrup, Niels; Borre, Michael; Hartmann, Arndt; Stöhr, Robert; Wach, Sven; Keck, Bastian; Seitz, Anna Katharina; Nawroth, Roman; Maurer, Tobias; Tulic, Cane; Simic, Tatjana; Junker, Kerstin; Horstmann, Marcus; Harving, Niels; Petersen, Astrid Christine; Calle, M Luz; Steyerberg, Ewout W; Beukers, Willemien; van Kessel, Kim E M; Jensen, Jørgen Bjerggaard; Pedersen, Jakob Skou; Malmström, Per-Uno; Malats, Núria; Real, Francisco X; Zwarthoff, Ellen C; Ørntoft, Torben Falck; Dyrskjøt, Lars.

    In: Cancer Cell, Vol. 30, No. 1, 11.07.2016, p. 27–42.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  20. Published

    Signs of low-grade systemic inflammation in female offspring of women with type 1 diabetes : The EPICOM study. / Boisen, A B; Knorr, S; Hansen, T K; Vlachova, Z; Bytoft, B; Damm, P; Beck-Nielsen, H; Jensen, D M; Møller, H J; Gravholt, C H.

    In: Diabetes & Metabolism, 01.07.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  21. Published

    SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism. / Christensen, Lise-Lotte; True, Kirsten Kallesøe; Hamilton, M.P.; Nielsen, Morten Muhlig; Djodji Damas, Nkerorema; Damgaard, Christian Kroun; Ongen, Halit; Dermitzakis, Emmanouil T; Bramsen, Jesper; Pedersen, Jakob Skou; Lund, Anders Henrik; Vang, Søren; Stribolt, Katrine; Madsen, Mogens Rørbæk; Laurberg, Søren; McGuire, Sean; Ørntoft, Torben Falck; Andersen, Claus Lindbjerg.

    In: Molecular Oncology, Vol. 10, No. 8, 26.06.2016, p. 1266-1282.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  22. Published

    Large-scale evaluation of SLC18A2 in prostate cancer reveals diagnostic and prognostic biomarker potential at three molecular levels. / Haldrup, Christa; Lynnerup, Anne-Sofie; Storebjerg, Tine Maj; Vang, Søren; Wild, Peter; Visakorpi, Tapio; Arsov, Christian; Schulz, Wolfgang A; Lindberg, Johan; Grönberg, Henrik; Egevad, Lars; Borre, Michael; Ørntoft, Torben Falck; Høyer, Søren; Sørensen, Karina Dalsgaard.

    In: Molecular Oncology, Vol. 10, No. 6, 8, 01.06.2016, p. 825-837.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  23. Published

    Novel diagnostic and prognostic classifiers for prostate cancer identified by genome-wide microRNA profiling. / Kristensen, Helle; Thomsen, Anni R; Haldrup, Christa; Dyrskjøt, Lars; Høyer, Søren; Borre, Michael; Mouritzen, Peter; Ørntoft, Torben F; Sørensen, Karina Dalsgaard.

    In: OncoTarget, Vol. 7, No. 21, 24.05.2016, p. 30760-30771.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  24. Published

    Repeated molecular genetic analysis in Brugada syndrome revealed a novel disease-associated large deletion in the SCN5A gene. / Krogh Brøndberg, Anders; Pedersen, Lisbeth Noerum; Nielsen, Jens Cosedis; Jensen, Henrik Kjaerulf.

    In: HeartRhythm Case Reports, Vol. 2, No. 3, 01.05.2016, p. 261-264.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  25. Published

    The Splicing Efficiency of Activating HRAS Mutations Can Determine Costello Syndrome Phenotype and Frequency in Cancer. / Hartung, Anne-Mette; Swensen, Jeff; Uriz, Inaki E; Lapin, Morten; Kristjansdottir, Karen; Petersen, Ulrika S S; Bang, Jeanne Mari V; Guerra, Barbara; Andersen, Henriette Skovgaard; Dobrowolski, Steven F; Carey, John C; Yu, Ping; Vaughn, Cecily; Calhoun, Amy; Larsen, Martin R; Dyrskjøt, Lars; Stevenson, David A; Andresen, Brage S.

    In: P L o S Genetics, Vol. 12, No. 5, 05.2016, p. e1006039.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  26. Published

    ProbFold : a probabilistic method for integration of probing data in RNA secondary structure prediction. / Sahoo, Sudhakar; Świtnicki, Michał P; Pedersen, Jakob Skou.

    In: Bioinformatics, Vol. 32, No. 17, 21.04.2016, p. 2626-2635.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  27. Published

    Inducible colorectal cancer in a genetic porcine model. / Callesen, Morten Møbjerg; Árnadóttir, Sigrid Salling; Jakobsen, Jannik E.; Høyer, Søren; Callesen, Henrik; Ørntoft, Torben Falck; Andersen, Claus Lindbjerg; Andersen, Lars Dyrskjøt.

    In: Transgenic Research, Vol. 25, No. 2, 01.04.2016, p. 225.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperConference abstract in journalResearchpeer-review

  28. Published

    Placebo-controlled, randomised clinical trial: high-dose resveratrol treatment for non-alcoholic fatty liver disease. / Heebøll, Sara; Kreuzfeldt, Martin; Hamilton-Dutoit, Stephen; Kjær Poulsen, Marianne; Stødkilde-Jørgensen, Hans; Møller, Holger Jon; Jessen, Niels; Thorsen, Kasper; Kristina Hellberg, Ylva; Bønløkke Pedersen, Steen; Grønbæk, Henning.

    In: Scandinavian Journal of Gastroenterology, Vol. 51, No. 4, 04.2016, p. 456-464.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  29. Published

    Molecular and biochemical investigations of patients with intermediate or severe hyperhomocysteinemia. / Sørensen, Jannie Tanderup; Gaustadnes, Mette; Stabler, Sally P; Allen, Robert H; Mudd, S Harvey; Hvas, Anne-Mette.

    In: Molecular Genetics and Metabolism, Vol. 117, No. 3, 03.2016, p. 344–350 .

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  30. Published

    Genomic Alterations in Liquid Biopsies from Patients with Bladder Cancer. / Birkenkamp-Demtröder, Karin; Nordentoft, Iver Kristiansen; Christensen, Emil; Høyer, Søren; Reinert, Thomas; Vang, Søren; Borre, Michael; Agerbæk, Mads; Jensen, Jørgen Bjerggaard; Ørntoft, Torben Falck; Dyrskjøt, Lars .

    In: European Urology, 21.01.2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  31. Published

    PINCAGE : Probabilistic integration of cancer genomics data for perturbed gene identification and sample classification. / Świtnicki, Michał P; Rasmussen, Malene Juul; Madsen, Tobias; Sørensen, Karina D; Pedersen, Jakob S.

    In: Bioinformatics, Vol. 32, No. 9, 06.01.2016, p. 1353-1365.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  32. Published

    A differential evolution optimization algorithm for reducing time series dimensionality. / Fuad, Marwan.

    2016 IEEE Congress on Evolutionary Computation (CEC). IEEE, 2016. p. 249-254.

    Research output: Contribution to book/anthology/report/proceedingArticle in proceedingsResearchpeer-review

  33. Published

    Analysis of circulating tumour DNA to monitor disease burden following colorectal cancer surgery. / Reinert, Thomas; Schøler, Lone Vedel; Thomsen, Rune; Tobiasen, Heidi; Vang, Søren; Nordentoft, Iver Kristiansen; Lamy, Philippe; Kannerup, Anne-Sofie; Mortensen, Frank Viborg; Stribolt, Katrine; Hamilton-Dutoit, Stephen Jacques; Laurberg, Søren; Pallisgaard, N.; Pedersen, Jakob Skou; Ørntoft, Torben Falck; Andersen, Claus Lindbjerg.

    In: Gut, Vol. 65, No. 4, 2016.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  34. Published

    Bivalent Regions of Cytosine Methylation and H3K27 Acetylation Suggest an Active Role for DNA Methylation at Enhancers. / Charlet, Jessica; Duymich, Christopher E; Lay, Fides D; Mundbjerg, Kamilla; Dalsgaard Sørensen, Karina; Liang, Gangning; Jones, Peter A.

    In: Molecular Cell, Vol. 62, No. 3, 2016, p. 422-31.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  35. Published

    Coronary artery anomalies in Turner Syndrome. / Viuff, Mette H; Trolle, Christian; Wen, Jan; Jensen, Jesper M; Nørgaard, Bjarne L; Gutmark, Ephraim J; Gutmark-Little, Iris; Mortensen, Kristian H; Gravholt, Claus Højbjerg; Andersen, Niels H.

    In: Journal of Cardiovascular Computed Tomography, Vol. 10, No. 6, 2016, p. 480-484.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  36. Published

    Ectodermal dysplasia with immunodeficiency caused by a branch-point mutation in IKBKG/NEMO. / Jørgensen, Sofie E.; Bøttger, Pernille; Kofod-Olsen, Emil; Holm, Mette; Mørk, Nanna; Ørntoft, Torben Falck; Sørensen, Uffe; Bernth-Jensen, Jens Magnus; Herlin, Troels; Veirum, Jens; Larsen, Carsten S.; Østergaard, Lars Jørgen; Hartmann, Rune; Christiansen, Mette; Mogensen, Trine.

    In: Journal of Allergy and Clinical Immunology, Vol. 138, No. 6, 2016, p. 1706-1709.e4.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  37. Published

    Klinefelter syndrome has increased brain responses to auditory stimuli and motor output, but not to visual stimuli or Stroop adaptation. / Wallentin, Mikkel; Skakkebæk, Anne; Bojesen, Anders; Fedder, Jens; Peter, Laurberg; Østergaard, John Rosendahl; Hertz, Jens Michael; Pedersen, Anders Degn; Gravholt, Claus Højbjerg.

    In: NeuroImage: Clinical, Vol. 11, 2016, p. 239-251.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  38. Published

    The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells. / Hansen, Stine Ninel; Ehlers, Natasja Spring; Zhu, Shida; Thomsen, Mathilde Borg Houlberg; Nielsen, Rikke Linnemann; Liu, Dongbing; Wang, Guangbiao; Hou, Yong; Zhang, Xiuqing; Xu, Xun; Bolund, Lars; Yang, Huanming; Wang, Jun; Moreira, Jose; Ditzel, Henrik J; Brünner, Nils; Schrohl, Anne-Sofie; Stenvang, Jan; Gupta, Ramneek.

    In: B M C Genomics, Vol. 17, No. 1, 2016, p. 442.

    Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review