CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1-Prkaca Gene Fusion is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma

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    Lars H Engelholm, Finsen Laboratory, Rigshospitalet, Copenhagen Biocenter, Copenhagen, Denmark; Biotech Research and Innovation Centre, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark., Anjum Riaz, Biotech Research and Innovation Centre, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark., Denise Serra, Biotech Research and Innovation Centre, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.,
  • Frederik Dagnæs-Hansen
  • Jens V Johansen, Biotech Research and Innovation Centre, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark., Eric Santoni-Rugiu, Department of Pathology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Steen H Hansen, Biotech Research and Innovation Centre, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark; GI Cell Biology Research Laboratory, Boston Children´s Hospital and Harvard Medical School, Boston, Massachusetts, USA., Francesco Niola, Biotech Research and Innovation Centre, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: morten.frodin@bric.ku.dk., Morten Frödin, Biotech Research and Innovation Centre, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: francesco.niola@outlook.com.
OriginalsprogEngelsk
Artikelnummer153
TidsskriftGastroenterology
Sider (fra-til)1662-1673
ISSN0016-5085
DOI
StatusUdgivet - dec. 2017

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