Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase

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    Roger W Hunter, School of Physiology, Pharmacology & Neuroscience, University of Bristol, Bristol, UK., Curtis C Hughey, Department of Molecular Physiology and Biophysics and the Vanderbilt Mouse Metabolic Phenotyping Center, Vanderbilt University, Nashville, TN, USA., Louise Lantier, Department of Molecular Physiology and Biophysics and the Vanderbilt Mouse Metabolic Phenotyping Center, Vanderbilt University, Nashville, TN, USA.,
  • Elias I Sundelin
  • Mark Peggie, MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, Dundee, UK., Elton Zeqiraj, Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK., Frank Sicheri, Departments of Biochemistry and Molecular Genetics, University of Toronto, Toronto, ON, Canada.,
  • Niels Jessen
  • David H Wasserman, Department of Molecular Physiology and Biophysics and the Vanderbilt Mouse Metabolic Phenotyping Center, Vanderbilt University, Nashville, TN, USA., Kei Sakamoto, Nestlé Institute of Health Sciences SA, Lausanne, Switzerland. kei.sakamoto@rd.nestle.com.
OriginalsprogEngelsk
TidsskriftNature Medicine
Vol/bind24
Tidsskriftsnummer9
Sider (fra-til)1395-1406
Antal sider12
ISSN1078-8956
DOI
StatusUdgivet - sep. 2018

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