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Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase

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  • Roger W Hunter, School of Physiology, Pharmacology & Neuroscience, University of Bristol, Bristol, UK.
  • ,
  • Curtis C Hughey, Department of Molecular Physiology and Biophysics and the Vanderbilt Mouse Metabolic Phenotyping Center, Vanderbilt University, Nashville, TN, USA.
  • ,
  • Louise Lantier, Department of Molecular Physiology and Biophysics and the Vanderbilt Mouse Metabolic Phenotyping Center, Vanderbilt University, Nashville, TN, USA.
  • ,
  • Elias I Sundelin
  • Mark Peggie, MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, Dundee, UK.
  • ,
  • Elton Zeqiraj, Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.
  • ,
  • Frank Sicheri, Departments of Biochemistry and Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • ,
  • Niels Jessen
  • David H Wasserman, Department of Molecular Physiology and Biophysics and the Vanderbilt Mouse Metabolic Phenotyping Center, Vanderbilt University, Nashville, TN, USA.
  • ,
  • Kei Sakamoto, Nestlé Institute of Health Sciences SA, Lausanne, Switzerland. kei.sakamoto@rd.nestle.com.
OriginalsprogEngelsk
TidsskriftNature Medicine
Vol/bind24
Nummer9
Sider (fra-til)1395-1406
Antal sider12
ISSN1078-8956
DOI
StatusUdgivet - sep. 2018

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