Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikel

DOI

    Peter K Joshi, Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, EH8 9AG, UK. peter.joshi@ed.ac.uk., Nicola Pirastu, Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AG, UK., Katherine A Kentistou, Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, EH16 4TJ, Scotland., Krista Fischer, Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia., Edith Hofer, Institute of Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, 8036, Austria., Katharina E Schraut, Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, EH16 4TJ, Scotland., David W Clark, Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AG, UK., Teresa Nutile, Institute of Genetics and Biophysics "A. Buzzati-Traverso" - CNR, Naples, 80131, Italy., Catriona L K Barnes, Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AG, UK., Paul R H J Timmers, Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AG, UK., Xia Shen, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-171 77, Stockholm, Sweden., Ilaria Gandin, Institute for Maternal and Child Health - IRCCS "Burlo Garofolo", 34137 Trieste, Italy., Aaron F McDaid, 1] Department of Medical Genetics, University of Lausanne, CH-1005 Lausanne, Switzerland. [2] Swiss Institute of Bioinformatics, CH-1015 Lausanne, Switzerland., Thomas Folkmann Hansen, Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Mental Health Services Copenhagen, Roskilde, DK-4000, Denmark., The Lundbeck Foundation Initiative for Integrative Psychiatric Research iPSYCH,Denmark., Scott D Gordon, Genetics and Computational Biology Department, QIMR Berghofer Medical Research Institute, Herston Road, Brisbane, QLD, 4006, Australia., Franco Giulianini, Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA., Thibaud S Boutin, MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK., Abdel Abdellaoui, Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, Amsterdam Public Health Institute (APH), Amsterdam, 1081BT, Netherlands., Wei Zhao, Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA., Carolina Medina-Gomez, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Traci M Bartz, Cardiovascular Health Research Unit, Departments of Biostatistics and Medicine, University of Washington, Seattle, WA, 98101, USA., Stella Trompet, Department of Cardiology, Leiden University Medical Center, Leiden, 2300RC, The Netherlands., Leslie A Lange, Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, 80045, USA., Laura Raffield, Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599-7264, USA., Ashley van der Spek, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Tessel E Galesloot, Department for Health Evidence, Radboud Institute for Health Sciences, Radboud university medical center, Nijmegen, 6500 HB, The Netherlands., Petroula Proitsi, MRC Unit for Lifelong Health & Ageing at UCL, University College London, London, WC1B 5JU, UK., Lisa R Yanek, Department of Medicine, GeneSTAR Research Program, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA., Lawrence F Bielak, Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA., Antony Payton, Centre for Epidemiology, Division of Population Health, Health Services Research & Primary Care, The University of Manchester, Manchester, Greater, Manchester, M13 9PL, UK., Federico Murgia, Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), (Affiliated Institute of the University of Lübeck, Lübeck, Germany), Bolzano, 39100, Italy., Maria Pina Concas, Institute of Genetic and Biomedical Research - Support Unity, National Research Council of Italy, Sassari, 07100, Italy., Ginevra Biino, Institute of Molecular Genetics, National Research Council of Italy, Pavia, 27100, Italy., Salman M Tajuddin, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore City, MD, 21224, USA., Ilkka Seppälä, Department of Clinical Chemistry, Fimlab Laboratories and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Najaf Amin, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Eric Boerwinkle, Health Science Center at Houston, UTHealth School of Public Health, University of Texas, Houston, TX, 77030, USA.,
  • Anders D Børglum
  • Archie Campbell, Centre for Genomic & Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Ellen W Demerath, Division of Epidemiology &Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55454, USA., Ilja Demuth, Institute for Medical and Human Genetics, Charité, Universitätsmedizin Berlin, Berlin, 13353, Germany., Jessica D Faul, Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48014, USA., Ian Ford, Robertson Center for biostatistics, University of Glasgow, Glasgow, G12 8QQ, UK., Alessandro Gialluisi, IRCCS Neuromed, Pozzilli (IS), 86077, Italy., Martin Gögele, Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), (Affiliated Institute of the University of Lübeck, Lübeck, Germany), Bolzano, 39100, Italy., MariaElisa Graff, Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27514, USA., Aroon Hingorani, Institute of Cardiovascular Science, University College London, London, WC1E 6BT, UK., Jouke-Jan Hottenga, Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, Amsterdam Public Health Institute (APH), Amsterdam, 1081BT, Netherlands., David M Hougaard, Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, 2300, Denmark., Mikko A Hurme, Department of Microbiology and Immunology, Fimlab Laboratories and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., M Arfan Ikram, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Marja Jylhä, Gerontology Research Center, Tampere, Finland, Faculty of Social Sciences, University of Tampere, Tampere, 33104, Finland., Diana Kuh, MRC Unit for Lifelong Health & Ageing at UCL, University College London, London, WC1B 5JU, UK., Lannie Ligthart, Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, Amsterdam Public Health Institute (APH), Amsterdam, 1081BT, Netherlands., Christina M Lill, Genetic and Molecular Epidemiology Group, Institute of Neurogenetics, University of Lübeck, 23562, Lübeck, Germany., Ulman Lindenberger, Max Planck UCL Centre for Computational Psychiatry and Ageing Research, Berlin, 14195, Germany., Thomas Lumley, Department of Statistics, University of Auckland, Auckland, 1010, New Zealand., Reedik Mägi, Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia., Pedro Marques-Vidal, Department of Medicine, Internal Medicine, Lausanne University Hospital, Lausanne, 1011, Switzerland., Sarah E Medland, Genetics and Computational Biology Department, QIMR Berghofer Medical Research Institute, Herston Road, Brisbane, QLD, 4006, Australia., Lili Milani, Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia., Reka Nagy, MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK., William E R Ollier, Division of Population Health, Health Services Research & Primary Care, School of Health Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, Greater Manchester, M13 9PL, UK., Patricia A Peyser, Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA., Peter P Pramstaller, Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), (Affiliated Institute of the University of Lübeck, Lübeck, Germany), Bolzano, 39100, Italy., Paul M Ridker, TH Chan School of Public Health, Harvard Medical School, Boston, MA, 02115, USA., Fernando Rivadeneira, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Daniela Ruggiero, Institute of Genetics and Biophysics "A. Buzzati-Traverso" - CNR, Naples, 80131, Italy., Yasaman Saba, Austrian Stroke Prevention Study, Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Graz, 8010, Austria., Reinhold Schmidt, Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, 8036, Austria., Helena Schmidt, Austrian Stroke Prevention Study, Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Graz, 8010, Austria., P Eline Slagboom, Section of Molecular Epidemiology, Department of medical statistics, Leiden University Medical Center, Leiden, 2300RC, The Netherlands., Blair H Smith, Division of Population Health Sciences, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, UK., Jennifer A Smith, Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48014, USA., Nona Sotoodehnia, Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, WA, 98101, USA., Elisabeth Steinhagen-Thiessen, Charité Research Group on Geriatrics, Charité, Universitätsmedizin Berlin, Berlin, 13347, Germany., Frank J A van Rooij, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., André L Verbeek, Department for Health Evidence, Radboud Institute for Health Sciences, Radboud university medical center, Nijmegen, 6500 HB, The Netherlands., Sita H Vermeulen, Department for Health Evidence, Radboud Institute for Health Sciences, Radboud university medical center, Nijmegen, 6500 HB, The Netherlands., Peter Vollenweider, Department of Medicine, Internal Medicine, Lausanne University Hospital, Lausanne, 1011, Switzerland., Yunpeng Wang, NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, 0450, Norway., Thomas Werge, The Lundbeck Foundation Initiative for Integrative Psychiatric Research iPSYCH,Denmark., Research Institute of Biological Psychiatry, Mental Health Centre, Sct. Hans, Copenhagen University Hospital, Roskilde, Demanrk, John B Whitfield, Genetics and Computational Biology Department, QIMR Berghofer Medical Research Institute, Herston Road, Brisbane, QLD, 4006, Australia., Alan B Zonderman, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore City, MD, 21224, USA., Terho Lehtimäki, Department of Clinical Chemistry, Fimlab Laboratories and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Michele K Evans, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore City, MD, 21224, USA., Mario Pirastu, Institute of Genetic and Biomedical Research - Support Unity, National Research Council of Italy, Sassari, 07100, Italy., Christian Fuchsberger, Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), (Affiliated Institute of the University of Lübeck, Lübeck, Germany), Bolzano, 39100, Italy., Lars Bertram, Neuroepidemiology and Ageing Research Group, School of Public Health, Imperial College, London, W6 8RP, UK., Neil Pendleton, Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, Greater Manchester, M13 9PL, UK., Sharon L R Kardia, Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA., Marina Ciullo, IRCCS Neuromed, Pozzilli (IS), 86077, Italy., Diane M Becker, Department of Medicine, GeneSTAR Research Program, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA., Andrew Wong, MRC Unit for Lifelong Health & Ageing at UCL, University College London, London, WC1B 5JU, UK., Bruce M Psaty, Kaiser Permanente Washington Health Research Institute, Seattle, WA, 98101, USA., Cornelia M van Duijn, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., James G Wilson, Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA., J Wouter Jukema, Department of Cardiology, Leiden University Medical Center, Leiden, 2300RC, The Netherlands., Lambertus Kiemeney, Department for Health Evidence, Radboud Institute for Health Sciences, Radboud university medical center, Nijmegen, 6500 HB, The Netherlands., André G Uitterlinden, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Nora Franceschini, Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27514, USA., Kari E North, Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27514, USA., David R Weir, Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48014, USA., Andres Metspalu, Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia., Dorret I Boomsma, Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, Amsterdam Public Health Institute (APH), Amsterdam, 1081BT, Netherlands., Caroline Hayward, MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK., Daniel Chasman, TH Chan School of Public Health, Harvard Medical School, Boston, MA, 02115, USA., Nicholas G Martin, Genetics and Computational Biology Department, QIMR Berghofer Medical Research Institute, Herston Road, Brisbane, QLD, 4006, Australia., Naveed Sattar, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, G12 8TD, UK., Harry Campbell, Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AG, UK., Tōnu Esko, 1] Institute for Molecular Medicine Finland (FIMM), University of Helsinki, FI-00014, Finland. [2] Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. [3] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts 02142, USA. [4] Psychiatric &Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Zoltán Kutalik, 1] Department of Medical Genetics, University of Lausanne, CH-1005 Lausanne, Switzerland. [2] Swiss Institute of Bioinformatics, CH-1015 Lausanne, Switzerland., James F Wilson, MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK.
OriginalsprogEngelsk
Artikelnummer910
TidsskriftNature Communications
Vol/bind8
ISSN2041-1723
DOI
StatusUdgivet - 13 okt. 2017

Se relationer på Aarhus Universitet Citationsformater

ID: 120343424