Thomas Vorup-Jensen

dr.med., Professor

Profile photo

Thomas Vorup-Jensen

Professor

  • Institut for Biomedicin - Forskning og uddannelse, Øst
Postaddresse:
Bartholins Allé 6
1242, 334
8000
Aarhus C
Danmark

E-mail: vorup-jensen@biomed.au.dk

Mobil: +4521489781

Telefon: +4587167853

Seneste Aktiviteter

13th ORPHEUS Conference on Creativity, Feedback and Diversity in Doctoral Studies

Vorup-Jensen, T. (Deltager)
24 aug. 201825 aug. 2018

The Second NorDoc PhD Summit "Think Open"

Vorup-Jensen, T. (Deltager)
23 aug. 201824 aug. 2018

Institute for Protein Innovation Ribbon-Cutting Ceremony

Vorup-Jensen, T. (Deltager)
21 maj 2018

Hong Kong University of Science & Technology - Aarhus University Joint Workshop in Bioengineering

Vorup-Jensen, T. (Deltager)
18 apr. 2018

The Strange Case of Glatiramer - from Multiple Sclerosis Drug to Antimicrobial Polypeptide

Vorup-Jensen, T. (Foredragsholder)
18 apr. 2018

Advisory Board

Vorup-Jensen, T. (Konsulent)
11 apr. 201813 apr. 2018

Soluble CD18 Integrins as Biomarkers for Inflammation

Vorup-Jensen, T. (Foredragsholder)
5 apr. 2018

4th NanoBrain Semi Annual Meeting

Vorup-Jensen, T. (Deltager)
4 apr. 2018

Institut for Biomedicin - Forskning og uddannelse, Øst (Organisation)

Vorup-Jensen, T. (Medlem)
28 mar. 2018

Institut for Biomedicin - Forskning og uddannelse, Øst (Organisation)

Vorup-Jensen, T. (Medlem)
27 mar. 2018

Presseklip

ASTRID2 åbner nye døre

Thomas Vorup-Jensen

13/09/2012

1 element af mediedækning

AU indvier den ultimative røntgen-kilde

Thomas Vorup-Jensen

10/09/2012

1 element af mediedækning

Aarhus Universitet får ny doktor i immunologi

Thomas Vorup-Jensen

05/09/2014

1 element af mediedækning

Algoritmer og proteinmolekyler

Thomas Vorup-Jensen

31/01/2018

1 mediebidrag

Bagklog på P1 m. Esben Kjær & Tobias Dybvad

Thomas Vorup-Jensen

09/12/2017

1 mediebidrag

Berlingske Tidende

Thomas Vorup-Jensen

04/12/2017

1 mediebidrag

DOKTORFORSVAR OM IMMUNSYSTEMET

Thomas Vorup-Jensen

04/09/2014

1 element af mediedækning

DR2 Dagen

Thomas Vorup-Jensen

05/12/2017

1 mediebidrag

Dansk biotekselskab på frierfødder

Thomas Vorup-Jensen

29/06/2016

1 element af mediedækning

Dansk gennembrud giver ny viden om bakterier

Thomas Vorup-Jensen

04/10/2016

1 element af mediedækning

Deadline: Interview m. Thomas Vorup-Jensen

Thomas Vorup-Jensen

13/01/2007

1 mediebidrag

Derfor er kolesterolmedicin godt for diabetikere og sklerosepatienter

Thomas Vorup-Jensen

05/07/2016

1 element af mediedækning

Det Sundhedsvidenskabelige Fakultets Ph.D. Dag 2011

Thomas Vorup-Jensen

14/01/2011

1 mediebidrag

Er der ukrudtsgift i vores vacciner?

Thomas Vorup-Jensen

07/05/2018

1 mediebidrag

Forskernes udstillingsvindue

Thomas Vorup-Jensen

16/01/2010

1 mediebidrag

Forskningen kom frem i lyset

Thomas Vorup-Jensen

17/01/2009

1 mediebidrag

Frihed falmer uden finanser

Thomas Vorup-Jensen

23/02/2009

1 mediebidrag

From MS to AMR

Thomas Vorup-Jensen

08/12/2017

1 mediebidrag

Interdisciplinaritet hvad og hvorfor?

Thomas Vorup-Jensen

06/01/2017

1 mediebidrag

Interview i Jyllandsposten: "Nye regler for cremer er for slappe"

Thomas Vorup-Jensen

19/02/2013

1 element af mediedækning

Ja tak: Kaffe kan holde flere sygdomme væk

Thomas Vorup-Jensen

18/01/2017

1 mediebidrag

KAFFEN ER MED TIL AT HOLDE DIG UNG

Thomas Vorup-Jensen

24/02/2017

1 mediebidrag

Kaffe forebygger (måske) alderdom

Thomas Vorup-Jensen

28/01/2017

1 mediebidrag

Kolesterolmedicin mod sclerose

Thomas Vorup-Jensen

15/08/2016

1 element af mediedækning

Kolesterolmedicins virkning på betændelsessygdomme kortlagt

Thomas Vorup-Jensen

05/07/2016

1 element af mediedækning

Lup på effekten af Copaxone

Thomas Vorup-Jensen & Bettina Winther Grumsen

05/09/2014

1 element af mediedækning

MS-Medikament gegen Multiresistenz

Thomas Vorup-Jensen

07/12/2017

1 mediebidrag

NY PROFESSOR MSO: Immunforsvaret under luppen

Thomas Vorup-Jensen

04/04/2013

1 element af mediedækning

NYT JOB

Thomas Vorup-Jensen

09/01/2018

1 mediebidrag

Navne i Noter

Thomas Vorup-Jensen

05/09/2014

1 element af mediedækning

Nyt professorat i biomedicin

Thomas Vorup-Jensen

10/01/2018

1 mediebidrag

Nyt professorat i biomedicin i Aarhus

Thomas Vorup-Jensen

08/01/2018

1 mediebidrag

Nyt våben mod farlige bakterier

Thomas Vorup-Jensen

04/12/2017

1 mediebidrag

P1 Morgen

Thomas Vorup-Jensen

06/12/2017

1 mediebidrag

P4 Morgen

Thomas Vorup-Jensen

13/01/2007

1 mediebidrag

P4 Morgen

Thomas Vorup-Jensen

14/01/2010

1 mediebidrag

Regional nyhedsudsendelse

Thomas Vorup-Jensen

28/01/2009

1 mediebidrag

Repurposing drugs could be key to fighting antibiotic resistance

Thomas Vorup-Jensen

16/11/2017

1 mediebidrag

Repurposing: Gammel medicin kan behandle flere nye sygdomme i fremtiden

Thomas Vorup-Jensen

09/12/2017

1 mediebidrag

Sclerosis medicine can fight multi – resistant bacteria

Thomas Vorup-Jensen

07/12/2017

1 mediebidrag

Sclerosis medicine can fight multi-resistant bacteria

Thomas Vorup-Jensen

22/11/2017

1 mediebidrag

Skarp, nysgerrig og original: 4 forskere mindes nobelprismodtager

Thomas Vorup-Jensen

29/06/2018

1 mediebidrag

Sklerosemedicin dræbte bakterier

Thomas Vorup-Jensen

17/12/2017

1 mediebidrag

Sklerosemedicin kan også slå multiresistente bakterier ihjel

Thomas Vorup-Jensen

05/12/2017

1 mediebidrag

Sklerosemedicin slår på forunderlig vis multiresistente bakterier ihjel

Thomas Vorup-Jensen

04/12/2017

1 mediebidrag

Spotlight on Denmark

Thomas Vorup-Jensen

04/11/2015

1 element af mediedækning

Særlige Bindingsmoilekyler i Kroppen skal undersøges

Thomas Vorup-Jensen

07/02/2013

1 element af mediedækning

Ugens podcast: Gammel medicin kan være sand guldgrube

Thomas Vorup-Jensen

07/12/2017

1 mediebidrag

Projekter

Atomic resolution insight on the principles of ligand recognition by integrin receptor aMb2

Vorup-Jensen, T. & Andersen, G. R.

01/08/201331/07/2016

NEURODIN: Center for study and prevention of the Neurodegenerative Inflammation NEURODIN

Romero-Ramos, M., Vorup-Jensen, T., Sanchez-Guajardo, V. & Brooks, D.

AU IDEAS AUFF

01/01/201431/12/2016

DIREKT: Disarming the intravascular innate immune response to improve treatment modalities for chronic kidney disease

Sutherland, D. S. & Vorup-Jensen, T.

01/12/201330/11/2017

NANOBRAIN: Imaging inflammation in vivo in ischemic stroke: development of a multimodal NANOprobe & BRAIN imaging methods

Vorup-Jensen, T.

01/10/201531/03/2019

Peer-reviewed Publikationer

Støy, S, Sandahl, TD, Hansen, AL, Deleuran, B, Vorup-Jensen, T, Vilstrup, H & Kragstrup, TW 2018, 'Correction to: Decreased monocyte shedding of the migration inhibitor soluble CD18 in alcoholic hepatitis (Clinical and Translational Gastroenterology, (2018), 9, 6, (160), 10.1038/s41424-018-0022-7)' Clinical and Translational Gastroenterology, bind 9, nr. 7, 171. DOI: 10.1038/s41424-018-0041-4
Støy, S, Sandahl, TD, Hansen, AL, Deleuran, B, Vorup-Jensen, T, Vilstrup, H & Kragstrup, TW 2018, 'Decreased monocyte shedding of the migration inhibitor soluble CD18 in alcoholic hepatitis' Clinical and Translational Gastroenterology, bind 9, nr. 6, s. 160. DOI: 10.1038/s41424-018-0022-7
Christiansen, SH, Murphy, RA, Juul-Madsen, K, Fredborg, M, Hvam, ML, Axelgaard, E, Skovdal, SM, Meyer, RL, Sorensen, UBS, Moeller, A, Nyengaard, JR, Norskov-Lauritsen, N, Wang, M, Gadjeva, M, Howard, KA, Davies, JC, Petersen, E & Vorup-Jensen, T 2017, 'The Immunomodulatory Drug Glatiramer Acetate is Also an Effective Antimicrobial Agent that Kills Gram-negative Bacteria' Scientific Reports, bind 7, 15653. DOI: 10.1038/s41598-017-15969-3
Kragstrup, TW, Juul-Madsen, K, Christiansen, SH, Zhang, X, Krog, J, Vorup-Jensen, T & Kjaergaard, AG 2017, 'Altered levels of soluble CD18 may associate immune mechanisms with outcome in sepsis' Clinical and experimental immunology, bind 190, nr. 2, s. 258-267. DOI: 10.1111/cei.13016
Pakula, MM, Maier, TJ & Vorup-Jensen, T 2017, 'Insight on the impacts of free amino acids and their metabolites on the immune system from a perspective of inborn errors of amino acid metabolism' Expert Opinion On Therapeutic Targets, bind 21, nr. 6, s. 611-626. DOI: 10.1080/14728222.2017.1323879
Christiansen, SH, Zhang, X, Juul-Madsen, K, Hvam, ML, Vad, BS, Behrens, MA, Thygesen, IL, Jalilian, B, Pedersen, JS, Howard, K, Otzen, DE & Vorup-Jensen, T 2017, 'The random co-polymer glatiramer acetate rapidly kills primary human leukocytes through sialic-acid-dependent cell membrane damage' B B A - Biomembranes, bind 1859, nr. 3, s. 425-437. DOI: 10.1016/j.bbamem.2017.01.001
von Euler Chelpin, M & Vorup-Jensen, T 2017, 'Targets and Mechanisms in Prevention of Parkinson's Disease through Immunomodulatory Treatments' Scandinavian Journal of Immunology, bind 85, nr. 5, s. 321-330. DOI: 10.1111/sji.12542
Stoey, S, Sandahl, TD, Hansen, AL, Deleuran, B, Vorup-Jensen, T, Vilstrup, H & Kragstrup, TW 2016, 'Augmented shedding of the leukocyte migration inhibitor soluble CD18 combined with increased plasma levels in human alcoholic hepatitis' Hepatology, bind 64, nr. 1 SUPP, s. 522A-522A.
Kugadas, A, Christiansen, SH, Sankaranarayanan, S, Surana, NK, Gauguet, S, Kunz, R, Fichorova, R, Vorup-Jensen, T & Gadjeva, M 2016, 'IMPACT OF MICROBIOTA ON RESISTANCE TO OCULAR PSEUDOMONAS AERUGINOSA–INDUCED KERATITIS' PLOS Pathogens.
Jensen, MR, Bajic, G, Zhang, X, Laustsen, AK, Koldsø, H, Skeby, KK, Schiøtt, B, Andersen, GR & Vorup-Jensen, T 2016, 'Structural basis for simvastatin competitive antagonism of complement receptor 3' Journal of Biological Chemistry. DOI: 10.1074/jbc.M116.732222
Howard, KA, Vorup-Jensen, T & Peer, D 2016, Nanomedicine. Advances in Delivery Science and Technology, 1 udg, Springer-Verlag New York, New York.
Huang, S-Y, Jensen, MR, Rosenberg, CA, Zhu, X-Q, Petersen, E & Vorup-Jensen, T 2016, 'In silico and in vivo analysis of Toxoplasma gondii epitopes by correlating survival data with peptide-MHC-I binding affinities' International Journal of Infectious Diseases, bind 48, s. 14-19. DOI: 10.1016/j.ijid.2016.04.014
Kragstrup, TW, Greisen, SR, Nielsen, MA, Rhodes, C, Stengaard-Pedersen, K, Hetland, ML, Hørslev-Petersen, K, Junker, P, Østergaard, M, Hvid, M, Vorup-Jensen, T, Robinson, WH, Sokolove, J & Deleuran, B 2016, 'The interleukin-20 receptor axis in early rheumatoid arthritis: novel links between disease-associated autoantibodies and radiographic progression' Arthritis Research & Therapy, bind 18, nr. 1, 61. DOI: 10.1186/s13075-016-0964-7
Zhang, X, Bajic, G, Andersen, GR, Christiansen, SH & Vorup-Jensen, T 2016, 'The cationic peptide LL-37 binds Mac-1 (CD11b/CD18) with a low dissociation rate and promotes phagocytosis' B B A - Proteins and Proteomics. DOI: 10.1016/j.bbapap.2016.02.013
Kragstrup, TW, Jalilian, B, Keller, KK, Zhang, X, Laustsen, JK, Stengaard-Pedersen, K, Hetland, ML, Hørslev-Petersen, K, Junker, P, Østergaard, M, Hauge, E-M, Hvid, M, Vorup-Jensen, T & Deleuran, B 2016, 'Changes in Soluble CD18 in Murine Autoimmune Arthritis and Rheumatoid Arthritis Reflect Disease Establishment and Treatment Response' PloS one, bind 11, nr. 2, s. e0148486. DOI: 10.1371/journal.pone.0148486
Roos, J, Grösch, S, Werz, O, Schröder, P, Ziegler, S, Fulda, S, Paulus, P, Urbschat, A, Kühn, B, Maucher, I, Fettel, J, Vorup-Jensen, T, Piesche, M, Matrone, C, Steinhilber, D, Parnham, MJ & Maier, TJ 2016, 'Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors: A basis for novel drugs targeting cancer cells?' Pharmacology & Therapeutics, bind 157, s. 43-64. DOI: 10.1016/j.pharmthera.2015.11.001
Bech, R, Jalilian, B, Agger, R, Iversen, L, Erlandsen, M, Otkjaer, K, Johansen, C, Paludan, SR, Rosenberg, CA, Kragballe, K & Vorup-Jensen, T 2016, 'Interleukin 20 regulates dendritic cell migration and expression of co-stimulatory molecules' Molecular and Cellular Therapies, bind 4, nr. 1. DOI: 10.1186/s40591-016-0046-x
Roos, J, Vorup-Jensen, T, Matrone, C, Maier, TJ & et al. 2016, 'On the role of lipoxygenases in pathogenesis of cancer.' Progress in inflammation research (submitted after invitation), bind Lipoxygenases in Inflammation, Progress in Inflammation Research, DOI 10.1007/978-3-319-27766-0_7.
Vorup-Jensen, T 2016, The Nanoscience of Polyvalent Binding by Proteins in the Immune Response. i K Howard, T Vorup-Jensen & D Peer (red), Nanomedicine. Springer-Verlag New York.
Kragstrup, TW, Greisen, S, Nielsen, MA, Rhodes, C, Stengaard-Pedersen, K, Hetland, ML, Horslev-Petersen, K, Junker, P, Ostergaard, M, Hvid, M, Vorup-Jensen, T, Robinson, WH, Sokolove, J & Deleuran, B 2015, 'The IL-20 Receptor Axis in Early Rheumatoid Arthritis' Arthritis & Rheumatology, bind 67.
Kläning, E, Christensen, BS, Bajic, G, Hoffmann, SV, Jones, NC, Callesen, MM, Andersen, GR, Sørensen, ES & Vorup-Jensen, T 2015, 'Multiple low-affinity interactions support binding of human osteopontin to integrin αXβ2' B B A - Proteins and Proteomics, bind 1854, nr. 8, s. 930-938. DOI: 10.1016/j.bbapap.2015.03.008
Stoey, S, Sandahl, TD, Deleuran, B, Vorup-Jensen, T, Vilstrup, H & Kragstrup, TW 2015, 'THE LEUKOCYTE MIGRATION INHIBITOR SOLUBLE CD18 INCREASES WITH SEVERITY OF HUMAN ALCOHOLIC HEPATITIS' Journal of Hepatology, bind 62, s. S776-S776.
Papazian, D, Chhoden, T, Arge, M, Vorup-Jensen, T, Nielsen, CH, Lund, K, Würtzen, PA & Hansen, S 2015, 'Polarization Affects Airway Epithelial Conditioning of Monocyte-Derived Dendritic Cells' American Journal of Respiratory Cell and Molecular Biology (Online). DOI: 10.1165/rcmb.2014-0183OC
Brinck-Jensen, N-S, Vorup-Jensen, T, Leutscher, PDC, Erikstrup, C & Petersen, E 2015, 'Immunogenicity of twenty peptides representing epitopes of the hepatitis B core and surface antigens by IFN-γ response in chronic and resolved HBV' B M C Immunology, bind 16, nr. 1, s. 65. DOI: 10.1186/s12865-015-0127-7
Pakula, MM, Maier, T & Vorup-Jensen, T 2015, 'Inborn errors of Metabolism and the Impact of free Amino Acids on the Immune System.' Expert Opinion On Therapeutic Targets, bind in revision.
Kragstrup, TW, Jalilian, B, Keller, KK, Stengaard-Pedersen, K, Hetland, ML, Horslev-Petersen, K, Junker, P, Ostergaard, M, Hauge, EM, Hvid, M, Vorup-Jensen, T & Deleuran, B 2014, 'Changes in Soluble CD18 Reflect Latency in the Immune System and Predict Radiographic Progression in Early Rheumatoid Arthritis' Arthritis & Rheumatology, bind 66, s. S863-S864.
Kläning, E, Christensen, B, Sørensen, ES, Vorup-Jensen, T & Jensen, JK 2014, 'Osteopontin binds multiple calcium ions with high affinity and independently of phosphorylation status' Bone, bind 66, s. 90-95. DOI: 10.1016/j.bone.2014.05.020
Munksgaard, PS, Skals, MG, Reinholdt, J, Poulsen, K, Jensen, MR, Yang, C, Leipziger, J, Vorup-Jensen, T & Praetorius, HA 2014, 'Sialic acid residues are essential for cell lysis mediated by leukotoxin from Aggregatibacter actinomycetemcomitans' Infection and Immunity, bind 82, nr. 6, s. 2219-28. DOI: 10.1128/IAI.01647-14
Bech, R, Otkjaer, K, Birkelund, S, Vorup-Jensen, T, Agger, R, Johansen, C, Iversen, L, Kragballe, K & Rømer, J 2014, 'Interleukin 20 protein locates to distinct mononuclear cells in psoriatic skin' Experimental Dermatology Online. DOI: 10.1111/exd.12371
Kragstrup, TW, Jalilian, B, Hvid, M, Kjærgaard, A, Ostgård, R, Schiøttz-Christensen, B, Jurik, AG, Robinson, WH, Vorup-Jensen, T & Deleuran, B 2014, 'Decreased plasma levels of soluble CD18 link leukocyte infiltration with disease activity in spondyloarthritis' Arthritis research & therapy, bind 16, nr. 1, s. R42. DOI: 10.1186/ar4471
Wittenborn, TR, Larsen, EKU, Nielsen, T, Rydtoft, LM, Hansen, L, Nygaard, JV, Vorup-Jensen, T, Kjems, J, Horsman, MR & Nielsen, NC 2014, 'Accumulation of nano-sized particles in a murine model of angiogenesis' Biochemical and Biophysical Research Communications, bind 443, nr. 2, s. 470-6. DOI: 10.1016/j.bbrc.2013.11.127
Vorup-Jensen, T 2014, 'Challenges and opportunities in fractionation of recombinant human mannan-binding lectin' Methods in molecular biology (Clifton, N.J.), bind 1100, s. 109-21. DOI: 10.1007/978-1-62703-724-2_9
Nielsen, GK & Vorup-Jensen, T 2014, Detection of Soluble CR3 (CD11b/CD18) by Time-Resolved Immunofluorometry. i M Gadjeva (red.), The Complement System: Methods and Protocols. Springer, Methods in Molecular Biology, bind 1100, s. 355-64. DOI: 10.1007/978-1-62703-724-2_30
Jalilian, B, Hill Christiansen, S, Einarsson, HB, Rasoli, M, Petersen, E & Vorup-Jensen, T 2013, 'Properties and prospects of adjuvants in influenza vaccination - messy precipitates or blessed opportunities?' Molecular and Cellular Therapies, bind 1, 2.
Bajic, G, Yatime, L, Sim, RB, Vorup-Jensen, T & Andersen, GR 2013, 'Structural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3' Proceedings of the National Academy of Sciences of the United States of America, bind 110, nr. 41, s. 16426–16431. DOI: 10.1073/pnas.1311261110
Rosenberg, C, Bovin, NV, Bram, LV, Flyvbjerg, E, Erlandsen, M, Vorup-Jensen, T & Petersen, E 2013, 'Age is an important determinant in humoral and T cell responses to immunization with hepatitis B surface antigen' Human Vaccines & Immunotherapeutics, bind 9, nr. 7, s. 1466-76. DOI: 10.4161/hv.24480
Kragstrup, TW, Vorup-Jensen, T, Deleuran, B & Hvid, M 2013, 'A simple set of validation steps identifies and removes false results in a sandwich enzyme-linked immunosorbent assay caused by anti-animal IgG antibodies in plasma from arthritis patients' SpringerPlus, bind 2, nr. 1, s. 263. DOI: 10.1186/2193-1801-2-263
Reinholdt, J, Poulsen, K, Brinkmann, CR, Hoffmann, SV, Stapulionis, R, Enghild, JJ, Jensen, UB, Boesen, T & Vorup-Jensen, T 2013, 'Monodisperse and LPS-free Aggregatibacter actinomycetemcomitans leukotoxin: Interactions with human β2 integrins and erythrocytes' BBA General Subjects, bind 1834, nr. 2, s. 546-558. DOI: 10.1016/j.bbapap.2012.12.004
Kragstrup, TW, Jalilian, B, Hvid, M, Kjærgaard, AG, Østgård, R, Schiøttz-Christensen, B, Jurik, AG, Vorup-Jensen, T & Deleuran, BW 2013, 'Decreased plasma levels of soluble CD18 link leukocyte migration and disease activity in spondyloarthritis.' Arthritis & Rheumatism, nr. 65 (suppl. 10).
Kragstrup, TW, Jalilian, B, Hvid, M, Kjærgaard, AG, Østgård, R, Schiøttz-Christensen, B, Jurik, AG, Vorup-Jensen, T & Deleuran, BW 2013, 'Inadequate CD18 shedding and increased depletion of soluble CD18 contributes to inflammatory acitivity in spondyloarthritis (P5090)' Journal of Immunology, nr. 190, 180.28.
Gjelstrup, LC, Kaspersen, JD, Behrens, MA, Pedersen, JS, Thiel, S, Kingshott, P, Oliveira, CLP, Thielens, NM & Vorup-Jensen, T 2012, 'The role of nanometer-scaled ligand patterns in polyvalent binding by large mannan-binding lectin oligomers' Journal of Immunology, bind 188, nr. 3, s. 1292-306. DOI: 10.4049/jimmunol.1103012
Vorup-Jensen, T 2012, 'Surface Plasmon Resonance Biosensing in Studies of the Binding Between β(2) Integrin I Domains and Their Ligands' Methods in Molecular Biology, bind 757, s. 55-71. DOI: 10.1007/978-1-61779-166-6_5
Jalilian, B, Einarsson, HB & Vorup-Jensen, T 2012, 'Glatiramer Acetate in Treatment of Multiple Sclerosis: A Toolbox of Random Co-Polymers for Targeting Inflammatory Mechanisms of both the Innate and Adaptive Immune System?' International Journal of Molecular Sciences (Online), bind 13, nr. 11, s. 14579-605. DOI: 10.3390/ijms131114579
Munksgaard, PS, Vorup-Jensen, T, Reinholdt, J, Söderström, CM, Poulsen, K, Leipziger, J, Praetorius, HA & Skals, M 2012, 'Leukotoxin from Aggregatibacter actinomycetemcomitans causes shrinkage and P2X receptor-dependent lysis of human erythrocytes' Cellular Microbiology, bind 14, nr. 12, s. 1904-20. DOI: 10.1111/cmi.12021
Vorup-Jensen, T & Peer, D 2012, 'Nanotoxicity and the importance of being earnest' Advanced Drug Delivery Reviews, bind 64, nr. 15, s. 1661-2. DOI: 10.1016/j.addr.2012.09.002
Vorup-Jensen, T 2012, 'On the roles of polyvalent binding in immune recognition: Perspectives in the nanoscience of immunology and the immune response to nanomedicines' Advanced Drug Delivery Reviews, bind 64, nr. 15, s. 1759-81. DOI: 10.1016/j.addr.2012.06.003
Wittenborn, T, Nielsen, T, Nygaard, JV, Larsen, EKU, Thim, T, Rydtoft, LM, Vorup-Jensen, T, Kjems, J, Nielsen, NC, Horsman, MR & Falk, E 2012, 'Ultra-High-Field DCE-MRI of Angiogenesis in a Novel Angiogenesis Mouse Model' Journal of Magnetic Resonance Imaging, bind 35, nr. 3, s. 703-710. DOI: 10.1002/jmri.22855
Vorup-Jensen, T & Boesen, T 2011, 'Protein ultrastructure and the nanoscience of complement activation' Advanced Drug Delivery Reviews. DOI: 10.1016/j.addr.2011.05.023
Bohn, AB, Nederby, L, Harbo, T, Skovbo, A, Vorup-Jensen, T, Krog, J, Jakobsen, J & Hokland, M 2011, 'The effect of IgG levels on the number of natural killer cells and their Fc receptors in chronic inflammatory demyelinating polyradiculoneuropathy' European Journal of Neurology, bind 18, nr. 6, s. 919-924.
Gjelstrup, LC, Andersen, SH, Petersen, SV, Enghild, JJ, Blom, AM, Vorup-Jensen, T & Thiel, S 2011, 'The role of higher-order protein structure in supporting binding by heteroclitic monoclonal antibodies: the monoclonal antibody KIM185 to CD18 also binds C4-binding protein' Molecular Immunology, bind 49, nr. 1-2, s. 38-47. DOI: 10.1016/j.molimm.2011.07.018
Dolatshahi-Pirouz, A, Jensen, TB, Vorup-Jensen, T, Riber-Hansen, R, Chevallier, J, Besenbacher, F, Foss, M & Sutherland, DS 2010, 'Synthesis of functional nanomaterials via colloidal mask templating and glancing angle deposition (GLAD)”' Advanced Engineering Materials, bind 12, nr. 9, s. 899-905.
Gjelstrup, LC, Boesen, T, Kragstrup, TW, Jørgensen, A, Klein, NJ, Thiel, S, Deleuran, BW & Vorup-Jensen, T 2010, 'Functionally Active CD11/CD18 Integrin Complexes are Shedded From the Leukocyte Membranes in Chronic Inflammation Disorders' Scandinavian Journal of Immunology, bind 71, nr. 6, s. 515-515.
Pedersen, MB, Zhou, X, Larsen, EKU, Sørensen, US, Kjems, J, Nygaard, JV, Nyengaard, JR, Meyer, RL, Boesen, T & Vorup-Jensen, T 2010, 'Curvature of Synthetic and Natural Surfaces is an Important Target Feature in Classical Pathway Complement Activation' Journal of Immunology, bind 184, nr. 4, s. 1931-1945. DOI: 10.4049/jimmunol.0902214
Gjelstrup, LC, Boesen, T, Kragstrup, TW, Jørgensen, A, Klein, NJ, Thiel, S, Deleuran, B & Vorup-Jensen, T 2010, 'Shedding of Large Functionally Active CD11/CD18 Integrin Complexes from Leukocyte Membranes during Synovial Inflammation Distinguishes Three Types of Arthritis through Differential Epitope Exposure' Journal of Immunology, bind 185, nr. 7, s. 4154-68. DOI: 10.4049/jimmunol.1000952
Rosenberg, C, De Craeye, S, Jongert, E, Gargano, N, Beghetto, E, Del Porto, P, Vorup-Jensen, T, Petersen, E & Rosenberg, CA 2009, 'Induction of partial protection against infection with Toxoplasma gondii genotype II by DNA vaccination with recombinant chimeric tachyzoite antigens' Vaccine, bind 27, nr. 18, s. 2489-98. DOI: 10.1016/j.vaccine.2009.02.058
Wittenborn, T, Nygaard, JV, Horsman, MR, Vorup-Jensen, T, Kjems, J, Thim, T, Nielsen, T, Larsen, EKU & Falk, E 2009, 'A Novel in Vivo Angiogenesis Mouse Model' Arteriosclerosis, Thrombosis, and Vascular Biology, nr. 7.
Rosenberg, CA, De Craeye, S, Jongert, E, Gargano, N, Beghetto, E, Del Porto, P, Vorup-Jensen, T & Petersen, JE 2009, 'Induction of partial protection against infection with Toxoplasma gondii genotype II by DNA vaccination with recombinant chimeric tachyzoite antigens' Vaccine, bind 27, s. 2489-98.
Schack, L, Stapulionis, R, Christensen, B, Kofod-Olsen, E, Sørensen, UBS, Vorup-Jensen, T, Sørensen, ES & Höllsberg, P 2009, 'Osteopontin enhances phagocytosis through a novel osteopontin receptor, the alphaXbeta2 integrin' Journal of Immunology, bind 182, nr. 11, s. 6943-50. DOI: 10.4049/jimmunol.0900065
Larsen, EKU, Nielsen, T, Wittenborn, T, Birkedal, H, Vorup-Jensen, T, Jakobsen, MH, Østergaard, L, Horsman, MR, Besenbacher, F, Howard, KA & Kjems, J 2009, 'Size-Dependent Accumulation of PEGylated Silane-Coated Magnetic Iron Oxide Nanoparticles in Murine Tumors' A C S Nano, bind 3, nr. 7, s. 1947-51. DOI: 10.1021/nn900330m
Kingshott, P, Arpanaei, A, Stapulionis, R & Vorup-Jensen, T 2008, 'Reduced attachment of blood mononuclear and alphaM-Beta2-expressing cells to surfaces coated with fish proteins.' Paper fremlagt ved 8th World Biomaterials Congress, Amsterdam, Holland, 17/12/2010, .
Stapulionis, R, Oliveira, C, Gjelstrup, MC, Pedersen, JS, Hokland, M, Hoffmann, SV, Poulsen, K, Jacobsen, C & Vorup-Jensen, T 2008, 'Structural insight into the function of myelin basic protein as a ligand for integrin αMβ2' Journal of Immunology, bind 180, s. 3946-3956.
Vorup-Jensen, T, Chi, L, Gjelstrup, LC, Jensen, UB, Jewett, CA, Xie, C, Shimaoka, M, Linhardt, RJ & Springer, TA 2007, 'Binding between the integrin alphaXbeta2 (CD11c/CD18) and heparin' Journal of Biological Chemistry, bind 282, nr. 42, s. 30869-77. DOI: 10.1074/jbc.M706114200
Dong, M, Xu, S, Oliveira, CLP, Pedersen, JS, Thiel, S, Besenbacher, F & Vorup-Jensen, T 2007, 'Conformational changes in mannan-binding lectin bound to ligand surfaces' Journal of Immunology, bind 178, nr. 5, s. 3016-22.
Dong, M, Xu, S, Oliveira, C, Pedersen, JS, Thiel, S, Besenbacher, F & Vorup-Jensen, T 2007, 'Conformational changes in mannan-binding lectin bound to ligand surfaces' The Journal of Immunology, bind 178, s. 3016-3022.
Vorup-Jensen, T, Waldron, TT, Astrof, N, Shimaoka, M & Springer, TA 2007, 'The connection between metal ion affinity and ligand affinity in integrin I domains.' Biochim. Biophys. Acta., bind 1774, s. 1148-1155.
Zhang, M, Takahashi, K, Alicot, EM, Vorup-Jensen, T, Kessler, B, Thiel, S, Jensenius, JC, Ezekowitz, RAB, Moore, FD & Carroll, MC 2006, 'Activation of the lectin pathway by natural IgM in a model of ischemia/reperfusion injury' Journal of Immunology, bind 177, nr. 7, s. 4727-34.
Zhang, M, Takahashi, K, Alicot, EM, Vorup-Jensen, T, Kessler, B, Thiel, S, Jensenius, JC, Ezekowitz, RA, Moore, FD & Carroll, MC 2006, 'Activation of the lectin pathway by natural IgM in a model of ischemia/reperfusion injury' J. Immunol., bind 177, s. 4727-34.
Zhang, M, Alicot, EM, Chiu, I, Li, J, Verna, N, Vorup-Jensen, T, Kessler, B, Shimaoka, M, Chan, R, Friend, D, Mahmood, U, Weissleder, R, Moore, FD & Carroll, MC 2006, 'Identification of the target self-antigens in reperfusion injury' J. Exp. Med., bind 203, s. 141-52.
Vorup-Jensen, T, Carman, CV, Shimaoka, M, Schuck, P, Svitel, J & Springer, TA 2005, 'Exposure of acidic residues as a danger signal for recognition of fibrinogen and other macromolecules by integrin αΧβ' Proc. Natl. Acad. Science USA, bind 102, s. 1614-9.
Vorup-Jensen, T, Ostermeier, C, Shimaoka, M, Hommel, U & Springer, TA 2003, 'Structure and allosteric regulation of the αΧβ2 integrin I domain' Proc. Natl. Acad. Science USA, bind 100, s. 1873-8.
Dagnaes-Hansen, F, Holst, HU, Jensen, MS, Vorup-Jensen, T, Flyvbjerg, A, Jensen, UB & Jensen, TG 2002, 'Physiological effects of human growth hormone produced after hydrodynamic gene transfer of a plasmid vector containing the human ubiquitin promotor' Journal of Molecular Medicine, bind 80, nr. 10, s. 665-70. DOI: 10.1007/s00109-002-0371-1
Vorup-Jensen, T, Jensen, UB, Liu, H, Kawasaki, T, Uemura, K, Thiel, S, Dagnaes-Hansen, F & Jensen, TG 2001, 'Tail-vein injection of mannan-binding lectin DNA leads to high expression levels of multimeric protein in liver' Molecular Therapy, bind 3, nr. 6, s. 867-74. DOI: 10.1006/mthe.2001.0335
Vorup-Jensen, T, Sørensen, ES, Jensen, UB, Schwaeble, W, Kawasaki, T, Ma, Y, Uemura, K, Wakamiya, N, Suzuki, Y, Jensen, TG, Takahashi, K, Ezekowitz, RA, Thiel, S & Jensenius, JC 2001, 'Recombinant expression of human mannan-binding lectin' International Immunopharmacology, bind 1, nr. 4, s. 677-87.
Thielens, NM, Cseh, S, Thiel, S, Vorup-Jensen, T, Rossi, V, Jensenius, JC & Arlaud, GJ 2001, 'Interaction properties of human mannan-binding lectin (MBL)-associated serine proteases-1 and -2, MBL-associated protein 19, and MBL' Journal of Immunology, bind 166, nr. 8, s. 5068-77.
Dahl, MR, Thiel, S, Matsushita, M, Fujita, T, Willis, AC, Christensen, T, Vorup-Jensen, T & Jensenius, JC 2001, 'MASP-3 and its association with distinct complexes of the mannan-binding lectin complement activation pathway' Immunity, bind 15, s. 127-135.
Dahl, MR, Thiel, S, Matsushita, M, Fujita, T, Willis, AC, Christensen, T, Vorup-Jensen, T & Jensenius, JC 2001, 'MASP-3 and its association with distinct complexes of the mannan-binding lectin complement activation pathway' Immunity, bind 15, nr. 1, s. 127-35.
Stover, C, Endo, Y, Takahashi, M, Lynch, NJ, Constantinescu, C, Vorup-Jensen, T, Thiel, S, Friedl, H, Hankeln, T, Hall, R, Gregory, S, Fujita, T & Schwaeble, W 2001, 'The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome 1p36.2-3' Genes and Immunity, bind 2, nr. 3, s. 119-27. DOI: 10.1038/sj.gene.6363745
Petersen, SV, Thiel, S, Jensen, L, Vorup-Jensen, T, Koch, C & Jensenius, JC 2000, 'Control of the classical and the MBL pathway of complement activation' Mol. Immunol, bind 37, s. 803-11.
Petersen, SV, Thiel, S, Jensen, L, Vorup-Jensen, T, Koch, C & Jensenius, JC 2000, 'Control of the classical and the MBL pathway of complement activation.' Molecular Immunology, bind 37, nr. 14, s. 803-11.
Vorup-Jensen, T, Petersen, SV, Hansen, AG, Poulsen, K, Schwaeble, W, Sim, RB, Reid, KB, Davis, SJ, Thiel, S & Jensenius, JC 2000, 'Distinct pathways of mannan-binding lectin (MBL)- and C1-complex autoactivation revealed by reconstitution of MBL with recombinant MBL-associated serine protease-2.' Journal of Immunology, bind 165, nr. 4, s. 2093-100.
Thiel, S, Petersen, SV, Vorup-Jensen, T, Matsushita, M, Fujita, T, Stover, CM, Schwaeble, WJ & Jensenius, JC 2000, 'Interaction of C1q and mannan-binding lectin (MBL) with C1r, C1s, MBL-associated serine proteases 1 and 2, and the MBL-associated protein MAp19.' Journal of Immunology, bind 165, nr. 2, s. 878-87.
Vorup-Jensen, T, Hjort, T, Abraham-Peskir, JV, Guttmann, P, Jensenius, JC, Uggerhøj, E & Medenwaldt, R 1999, 'Outstanding contribution: X-ray microscopy of human spermatozoa shows change of mitochondrial morphology after capacitation' Hum. Reprod., bind 14, s. 880-884.
Stover, CM, Thiel, S, Thelen, M, Lynch, NJ, Vorup-Jensen, T, Jensenius, JC & Schwaeble, WJ 1999, 'Two constituents of the initiation complex of the mannan-binding elctin activation pathway of complement are encoded by a single structural gene' J. Immunol., bind 162, s. 3481-90.
Stover, CM, Thiel, S, Thelen, M, Lynch, NJ, Vorup-Jensen, T, Jensenius, JC & Schwaeble, WJ 1999, 'Two constituents of the initiation complex of the mannan-binding lectin activation pathway of complement are encoded by a single structural gene' Journal of Immunology, bind 162, nr. 6, s. 3481-90.
Vorup-Jensen, T, Hjort, T, Abraham-Peskir, JV, Guttmann, P, Jensenius, JC, Uggerhøj, E & Medenwaldt, R 1999, 'X-ray microscopy of human spermatozoa shows change of mitochondrial morphology after capacitation' Human Reproduction, bind 14, nr. 4, s. 880-4.
Laursen, SB, Dalgaard, TS, Thiel, S, Lim, BL, Vorup-Jensen, T, Juul-Madsen, HR, Takahashi, A, Hamana, T, Kawakami, M & Jensenius, JC 1998, 'Cloning and sequencing of a cDNA encoding chicken mannan-binding lectin (MBL) and comparison with mammalian analogues' Immunology, bind 93, s. 421-30.
Vorup-Jensen, T, Jensenius, JC & Thiel, S 1998, 'MASP-2, the C3 convertase generating protease of the MBLectin complement activating pathway' Immunobiology, bind 199, nr. 2, s. 348-57.
Vorup-Jensen, T, Jensenius, JC & Thiel, S 1998, 'MASP-2, the C3 convertase generating protease of the MBLectin complement activating pathway' Immunobiology, bind 199, s. 348-57.
Thiel, S, Vorup-Jensen, T, Stover, CM, Schwaeble, W, Laursen, S, Poulsen, K, Willis, AC, Eggleton, P, Hansen, S, Holmskov, UL, Reid, KB & Jensenius, JC 1997, 'A second serine protease associated with mannan-binding lectin that activates complement' Nature, bind 386, nr. 6624, s. 506-10. DOI: 10.1038/386506a0
Thiel, S, Vorup-Jensen, T, Stover, CM, Schwaeble, W, Laursen, SB, Poulsen, K, Willis, AC, Eggleton, P, Hansen, S, Holmskov, U, Reid, KB & Jensenius, JC 1997, 'A second serine protease associated with mannan-binding lectin that activates complement' Nature, bind 386, s. 506-10.