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Peter Andreasen

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  1. 2011
  2. Udgivet

    Structural basis for recognition of urokinase-type plasminogen activator by plasminogen activator inhibitor-1. / Lin, Zhonghui ; Jiang, Longguang ; Yuan, Cai ; Jensen, Jan Kristian ; Zhang, Xu ; Luo, Zhipu ; Furie, Barbara C ; Furie, Bruce ; Andreasen, Peter A ; Huang, Mingdong.

    I: Journal of Biological Chemistry, Vol. 286, Nr. 9, 04.03.2011, s. 7027-32.

    Publikation: Forskning - peer review › Tidsskriftartikel

  3. Udgivet

    DNA methylation profiles of protease nexin 1 gene in human tumour cells. / Gao, Shan ; Andreasen, Peter.

    I: Chin J Cancer Res, Vol. 23, Nr. 2, 05.2011, s. 92-98.

    Publikation: Forskning - peer review › Tidsskriftartikel

  4. Udgivet

    Activation of the zymogen to urokinase-type plasminogen activator is associated with increased interdomain flexibility. / Behrens, Manja A ; Bøtkjær, Kenneth Alrø ; Goswami, Sumit ; Oliveira, Cristiano L P ; Jensen, Jan K ; Schar, Christine R ; Declerck, Paul J ; Peterson, Cynthia B ; Andreasen, Peter A ; Pedersen, Jan Skov.

    I: Journal of Molecular Biology, Vol. 411, Nr. 2, 12.08.2011, s. 417-29.

    Publikation: Forskning - peer review › Tidsskriftartikel

  5. Udgivet

    Targeting the autolysis loop of urokinase-type plasminogen activator with conformation-specific monoclonal antibodies. / Bøtkjær, Kenneth Alrø ; Fogh, Sarah ; Bekes, Erin C ; Chen, Zhuo ; Blouse, Grant E ; Jensen, Janni M ; Mortensen, Kim ; Huang, Mingdong ; Deryugina, Elena ; Quigley, James P ; Declerck, Paul J ; Andreasen, Peter A.

    I: Biochemical Journal, Vol. 438, Nr. 1, 15.08.2011, s. 39-51.

    Publikation: Forskning - peer review › Tidsskriftartikel

  6. Udgivet

    Activation of Pro-uPA is Critical for Initial Escape from the Primary Tumor and Hematogenous Dissemination of Human Carcinoma Cells. / Bekes, Erin ; Deryugina, Elena ; Kuprianova, Tatyana ; Zajac, Ewa ; Bøtkjær, Kenneth Alrø ; Andreasen, Peter ; Quigley, James .

    I: NeoPlasia, Vol. 13, Nr. 9, 09.2011, s. 806-821.

    Publikation: Forskning - peer review › Tidsskriftartikel

  7. Udgivet

    Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability. / Jensen, Jan K ; Thompson, Lawrence C ; Bucci, Joel C ; Nissen, Poul ; Gettins, Peter G W ; Peterson, Cynthia B ; Andreasen, Peter A ; Morth, J Preben.

    I: Journal of Biological Chemistry, Vol. 286, Nr. 34, 2011, s. 29709-17.

    Publikation: Forskning - peer review › Tidsskriftartikel

  8. Udgivet

    Elucidation of the contribution of active site and exosite interactions to affinity and specificity of peptidylic serine protease inhibitors, using non-natural arginine analogues.. / Andreasen, Peter ; Jensen, Jan Kristian ; Hosseini, Masood ; Jiang, L ; Sørensen, Hans Peter ; Christensen, A. ; Fogh, Sarah ; Yuan, C. ; Andersen, Lisbeth Moreau ; Huang, M. ; Jensen, K.J..

    I: Molecular Pharmacology, Vol. 80, 2011, s. 585-597.

    Publikation: Forskning - peer review › Tidsskriftartikel

  9. Udgivet

    Practical Course in Molecular Cell Biology. / Pedersen, Lene ; Hansen, Mariann Fagernæs ; Pakula, Malgorzata Maria ; Lassen, Louise Berkhoudt ; Dillschneider, Philipp ; marlar, saw ; Bechstein, Stefanie ; Kromann-Hansen, Tobias ; Koffman, Jennifer Skaarup ; Torvund, Julie ; Wolf, Gernot ; Domanski, Michal ; Kousted, Tina Mostrup ; Nejsum, Lene Niemann ; Sørensen, Hans Peter ; Schmitt-John, Thomas ; Andreasen, Peter ; Martensen, Pia Møller.

    2011.

    Publikation: Undervisning › Kompendium/lecture notes

  10. Udgivet

    RNA aptamers to the cancer-associated proteins UPA and PAI-1 with therapeutic potential. / Dupont, Daniel Miotto ; Madsen, Jeppe Buur ; Bøtkjær, Kenneth Alrø ; Tavitian, Bertrand ; Duconge, Frederic ; Kjems, Jørgen ; Andreasen, Peter.

    I: Nucleic Acid Therapeutics, Vol. 21, Nr. 5, 2011.

    Publikation: Forskning - peer review › Konferenceartikel

  11. Udgivet

    The binding mechanism of a peptidylic cyclic serine protease inhibitor.. / Svane, Anna Sigrid P. ; Sørensen, Hans Peter ; Jensen, Jan Kristian ; Hosseini, Masood ; Chen, Zhuo ; Weydert, C. ; Nielsen, Jakob Toudahl ; Christensen, Anni ; Yuan, C. ; Jensen, K.J. ; Nielsen, Niels Christian ; Malmendal, Anders ; Huang, M. ; Andreasen, Peter.

    I: Journal of Molecular Biology, 2011, s. 235-250.

    Publikation: Forskning - peer review › Tidsskriftartikel

  12. 2010
  13. Udgivet

    RNA aptamers as conformational probes and regulatory agents for plasminogen activator inhibitor-1. / Madsen, Jeppe B ; Dupont, Daniel Miotto ; Andersen, Thomas B ; Nielsen, Anne F ; Sang, Lu ; Brix, Ditte M ; Jensen, Jan K ; Broos, Thomas ; Hendrickx, Maarten L V ; Christensen, Anni ; Kjems, Jørgen ; Andreasen, Peter A.

    I: Biochemistry, Vol. 49, Nr. 19, 18.05.2010, s. 4103-15.

    Publikation: Forskning - peer review › Tidsskriftartikel

  14. Udgivet

    Serum-stable RNA aptamers to urokinase-type plasminogen activator blocking receptor binding. / Dupont, Daniel Miotto ; Madsen, Jeppe Buur ; Hartmann, Roland Karl ; Tavitian, Bertrand ; Ducongé, Frédéric ; Kjems, Jørgen ; Andreasen, Peter André.

    I: RNA (New York, N.Y.), Vol. 16, Nr. 12, 01.12.2010, s. 2360-9.

    Publikation: Forskning - peer review › Tidsskriftartikel

  15. Udgivet

    Epigenetic Alterations of the SERPINE1 Gene in Oral Squamous Cell Carcinomas and Normal Oral Mucosa. / Gao, Shan ; Nielsen, Boye Schnack ; Krogdahl, Annelise ; Sørensen, Jens Ahm ; Tagesen, Jan ; Dabelsteen, Sally ; Dabelsteen, Erik ; Andreasen, Peter.

    I: Genes, Chromosomes & Cancer, Vol. 49, Nr. 6, 2010, s. 526-538.

    Publikation: Forskning - peer review › Tidsskriftartikel

  16. 2009
  17. Udgivet

    Interactions of plasminogen activator inhibitor-1 with vitronectin involve an extensive binding surface and induce mutual conformational rearrangements. / Blouse, Grant E ; Dupont, Daniel Miotto ; Schar, Christine R ; Jensen, Jan K ; Minor, Kenneth H ; Anagli, John Y ; Gårdsvoll, Henrik ; Ploug, Michael ; Peterson, Cynthia B ; Andreasen, Peter A.

    I: Biochemistry, Vol. 48, Nr. 8, 03.03.2009, s. 1723-35.

    Publikation: Forskning - peer review › Tidsskriftartikel

  18. Udgivet

    Non-proteolytic induction of catalytic activity into the single-chain form of urokinase-type plasminogen activator by dipeptides. / Bøtkjær, Kenneth Alrø ; Byszuk, A. ; Andersen, Lisbeth Moreau ; Christensen, Anni ; Andreasen, Peter ; Blouse, Grant.

    I: Biochemistry, Vol. 48, Nr. 40, 25.08.2009, s. 9606-9617.

    Publikation: Forskning - peer review › Tidsskriftartikel

  19. Udgivet

    Comparative analysis of metastasis variants derived from human prostate carcinoma cells: roles in intravasation of VEGF-mediated angiogenesis and uPA-mediated invasion. / Conn, Erin M ; Bøtkjær, Kenneth Alrø ; Kupriyanova, Tatyana A ; Andreasen, Peter A ; Deryugina, Elena I ; Quigley, James P.

    I: American Journal of Pathology, Vol. 175, Nr. 4, 01.10.2009, s. 1638-52.

    Publikation: Forskning - peer review › Tidsskriftartikel

  20. Udgivet

    A novel mode of intervention with serine protease activity : Targeting zymogen activation. / Blouse, Grant ; Bøtkjær, Kenneth Alrø ; Byszuk, Aleksandra a. ; Jensen, Janni Mosgaard ; Mortensen, Kim Kusk ; deryugina, elena ; Quigley, James P. ; Andreasen, Peter.

    I: Journal of Biological Chemistry, 2009, s. 4747-4657.

    Publikation: Forskning - peer review › Tidsskriftartikel

  21. Udgivet

    Biochemical properties of plasminogen activator inhibitor-1. / Andreasen, Peter ; Dupont, Daniel Miotto ; Madsen, Jeppe Buur ; Kristensen, Thomas Kielsgaard ; Bødker, Julie Støve ; Blouse, Grant ; Wind, Troels.

    I: Frontiers in Bioscience, Vol. 14, 2009, s. 1337-1361.

    Publikation: Forskning › Review

  22. Udgivet

    Practical course in Molecular Cell Biology. / Pedersen, Lene ; Pedersen, Lasse Ebdrup ; Bøtkjær, Kenneth Alrø ; Vestergaard, Anna Lindeløv ; Ward, Sarah ; Andersen, Lisbeth Moreau ; Mikkelsen, Jakob Hauge ; Bechstein, Stefanie ; Lassen, Louise Berkhoudt ; Liu, Zhou ; Beer, Christiane ; Chen, Zhou ; Lykke-Andersen, Søren ; Gao, Shan ; Sørensen, Hans Peter ; Duch, Mogens R. ; Schmitt-John, Thomas ; Andreasen, Peter ; Martensen, Pia Møller.

    1. udg. Århus, 2009. 61 s.

    Publikation: Undervisning › Kompendium/lecture notes

  23. Udgivet

    The Influence of glancing angle deposited (GLAD) nano-rough platinum surfaces  on the adsorption of fibrinogen and the proliferation of primary human fibroblasts. / Dolatshahi-Pirouz, Alireza ; Pennisi, C. P. ; Skeldal, Sune ; Foss, Morten ; Chevallier, Jacques ; Zachar, V. ; Andreasen, Peter ; Yoshida, K. ; Besenbacher, Flemming.

    I: Nanotechnology, Vol. 20, 2009, s. 095101.

    Publikation: Forskning - peer review › Tidsskriftartikel

  24. 2008
  25. Udgivet

    A cyclic peptidylic inhibitor of murine urokinase-type plasminogen activator. Changing species specificity by substitution of a single residue. / Andersen, Lisbeth Moreau ; Wind, Troels ; Hansen, Hanne Demant ; Andreasen, Peter.

    I: Biochemical Journal, Vol. 412, 2008, s. 447-457.

    Publikation: Forskning - peer review › Tidsskriftartikel

  26. Udgivet

    A new way of targeting protease-receptor binding: Selection of uPA binding RNA aptamers inhibiting its association to its receptor uPAR. / Dupont, Daniel Miotto ; Kjems, Jørgen ; Andreasen, Peter ; Madsen, Jens Christian Bredahl.

    I: Acta Pathologica Microbiologica et Immunologica Scandinavica, 2008, s. 443-443.

    Publikation: Forskning › Konferenceabstrakt i tidsskrift

  27. Udgivet

    A peptide accelerating the conversion of plasminogen activator inhibitor-1 to an inactive latent state. / Mathiasen, Lisa ; Dupont, Daniel Miotto ; Christensen, Anni ; Blouse, Grant ; Jensen, Jan Kristian ; Gils, Ann ; Declerck, Paul J. ; Wind, Troels ; Andreasen, Peter.

    I: Molecular Pharmacology, Vol. 74, Nr. 3, 2008, s. 641-653.

    Publikation: Forskning - peer review › Tidsskriftartikel

  28. Udgivet

    Characterisation of a site on pai-1 that binds to vitronectin outside of the somatomedin B domain. / Schar, christine r. ; Jensen, Jan Kristian ; Christensen, Anni ; Blouse, Grant ; Peterson, Cynthia B. ; Andreasen, Peter.

    I: Journal of Biological Chemistry, Vol. 283, Nr. 42, 2008, s. 28487-28496.

    Publikation: Forskning - peer review › Tidsskriftartikel

  29. Udgivet

    Engineered antagonists of uPA and PAI-1. / Andreasen, Peter ; Andersen, Lisbeth Moreau ; Stoppelli, M. Patrizia ; Votta, Giuseppina.

    I: The Cancer Degradome: Proteases and Cancer Biology. red. / Dylan Edwards. New York : Springer, 2008. s. 721-758.

    Publikation: Forskning › Review

  30. Udgivet

    Novel modes of oestrogen receptor agonism and antagonism by hydroxylated and chlorinated biphenyls, revealed by conformation-specific peptide recognition patterns. / Sumbayev, Vadim V. ; Jensen, Jan Kristian ; Hansen, Jacob Ask ; Andreasen, Peter.

    I: Molecular and Cellular Endocrinology, Vol. 287, 2008.

    Publikation: Forskning - peer review › Tidsskriftartikel

  31. Udgivet

    Overexpression of protease nexin-1 mRNA and protein in oral squamous cell carcinomas. / Gao, Shan ; Krogdahl, Annelise ; Sørensen, j.a. ; Kousted, Tina M. ; Dabelsteen, Erik ; Andreasen, Peter.

    I: Oral Oncology, Vol. 44, 2008, s. 309-313.

    Publikation: Forskning - peer review › Tidsskriftartikel

  32. Udgivet

    Plasminogen activator inhibitor-1 (PAI-1): A molecule at the crossroads to cell survival or cell death. / Andreasen, Peter ; Kietzmann, Thomas.

    I: Thrombosis and Haemostasis, Vol. 100, Nr. 12, 2008, s. 965-968.

    Publikation: Forskning - peer review › Tidsskriftartikel

  33. Udgivet

    Redirection of the reaction between activated protein C and a serpin to the substrate pathway. / Andreasen, Peter ; Komissarov, Andrey A. ; Declerck, Paul J. ; Kamikubo, Yuichi ; Zhou, Aiwu ; Gruber, Andras.

    I: Thrombosis Research, 2008, s. 397-404.

    Publikation: Forskning - peer review › Tidsskriftartikel

  34. 2007
  35. Udgivet

    A novel type of agent blocking the association of uPA to its receptor uPAR: uPA-binding aptamers. / Dupont, Daniel Miotto ; Madsen, J.B. ; Kjems, Jørgen ; Andreasen, Peter.

    2007. Abstract from XIth International Workshop on Molecular and Cellular Biology of Plasminogen Activation, Stockholm, Sverige.

    Publikation: Forskning › Konferenceabstrakt til konference

  36. Udgivet

    Conformational probes and activity regulators of plasminogen activator inhibitor-1, isolated from phage-displayed disulphide bridge-constrained peptide libraries. / Dupont, Daniel Miotto ; Jensen, J.K. ; Mathiasen, Lisa ; Blouse, Grant ; Wind, Troels ; Andreasen, Peter.

    2007. Poster session presented at XIth International Workshop on Molecular and Cellular Biology of Plasminogen Activation, Stockholm, Sverige.

    Publikation: Forskning › Poster

  37. Udgivet

    Discovery of a novel zymogen targeting inhibitor of urokinase-type plasminogen activator: Evidence for structural flexibility of the protease domain. / Blouse, Grant ; Bøtkjær, Kenneth Alrø ; Deryugina, E.I. ; Kristiansen, Signe Kjelgaard ; Byzuk, O. ; Mortensen, Kim Kusk ; Quigley, J.P. ; Andreasen, Peter.

    2007. Abstract from XIth International Workshop on Molecular and Cellular Biology of Plasminogen Activation, Stockholm, Sverige.

    Publikation: Forskning › Konferenceabstrakt til konference

  38. Udgivet

    Dissecting serpin-protease reaction pathways by the use of monoclonal antibodies. / Bødker, J.S. ; Blouse, Grant ; Dupont, Daniel Miotto ; Andreasen, Peter.

    2007. Poster session presented at XIth International Workshop on Molecular and Cellular Biology of Plasminogen Activation, Stockholm, Sverige.

    Publikation: Forskning › Poster

  39. Udgivet

    Methylation of the PAI-1 gene in oral squamous cell carcinomas and normal oral mucosa. / Gao, Shan ; Krogdahl, A. ; Sørensen, J.A. ; Dabelsteen, E. ; Andreasen, Peter.

    2007. Poster session presented at XIth International Workshop on Molecular and Cellular Biology of Plasminogen Activation, Stockholm, Sverige.

    Publikation: Forskning › Poster

  40. Udgivet

    New pharmacophore for serine protease inhibition revealed by crystal structure of human urokinase-type plasminogen activator complexed with a cyclic peptidyl inhibitor, upain-1. / Zhao, G. ; Yuan, C. ; Wind, Troels ; Andreasen, Peter ; Huang, Z. ; Huang, M..

    I: J. Struct. Biol., Vol. 160, 2007.

    Publikation: Forskning - peer review › Tidsskriftartikel

  41. Udgivet

    Overexpression of protease nexin-1 mRNA in oral squamous cell carcinomas. / Gao, Shan ; Kroghdahl, A. ; Sørensen, S.A. ; Dabelsteen, E. ; Andreasen, Peter.

    2007. Poster session presented at XIth International Workshop on Molecular and Cellular Biology of Plasminogen Activation, Stockholm, Sverige.

    Publikation: Forskning › Poster

  42. Udgivet

    PAI-1 - a potential therapeutic target in cancer. / Andreasen, Peter.

    I: Current Drug Targets, Vol. 8, 2007, s. 1030-1041.

    Publikation: Forskning - peer review › Tidsskriftartikel

  43. Udgivet

    PAI-1 - a potential therapeutic target in cancer. / Andreasen, Peter.

    I: Current Drug Targets, Vol. 8, 2007, s. 1020-1041.

    Publikation: Forskning - peer review › Tidsskriftartikel

  44. Udgivet

    PAI-1-vitronectin interactions involve an extended binding surface and mutual conformational rearrangements. / Blouse, Grant ; Peterson, C.B. ; Dupont, Daniel Miotto ; Ploug, M ; Gårdsvoll, H. ; Perro, C.R. ; Minor, K.H. ; Shore, J.D. ; Andreasen, Peter.

    2007. Poster session presented at XIth International Workshop on Molecular and Cellular Biology of Plasminogen Activation, Stockholm, Sverige.

    Publikation: Forskning › Poster

  45. Udgivet

    Plasminogen activator inhibitor-1 is a major physiological inhibitor of factor VII-activating protease.. / Wygrecka, M. ; Markart, P. ; Morty, R.E. ; Kanse, S.M. ; Andreasen, Peter ; Wind, Troels ; Vuenther, V. ; Preissner, K.T..

    I: Journal of Biological Chemistry, 2007.

    Publikation: Forskning - peer review › Tidsskriftartikel

  46. Udgivet

    Plasminogen activator inhibitor-1 is a major physiological inhibitor of factor VII-activating protease.. / Andreasen, Peter ; Wind, Troels ; Wygrecka, M. ; Markart, P. ; Morty, R.E. ; Guenther, A. ; Preissner, K.T..

    I: Journal of Biological Chemistry, Vol. 282, 2007, s. 21671-21682.

    Publikation: Forskning - peer review › Tidsskriftartikel

  47. Udgivet

    Structural basis of specificity of a peptidyl urokinase inhibitor, upain-1. / Andreasen, Peter ; Wind, Troels ; Huang, Mingdong ; Zhao, G. ; Yuan, C. ; Huang, Z..

    I: Journal of Structural Biology, Vol. 160, 2007, s. 1-10.

    Publikation: Forskning - peer review › Tidsskriftartikel

  48. Udgivet

    Urokinase plasminogen activator and plasminogen activator inhibitor type-1 in non-small cell lung cancer: Relation to prognosis and angiogenesis.. / Offersen, Birgitte Vrou ; Pfeiffer, P. ; Andreasen, Peter ; Overgaard, J..

    I: Lung Cancer, 2007.

    Publikation: Forskning - peer review › Tidsskriftartikel

  49. Udgivet

    Urokinase plasminogen activator and plasminogen activator inhibitor type-1 in nonsmall-cell lung cancer: relation to prognosis and angiogenesis.. / Offersen, Birgitte Vrou ; Pfeiffer, Per ; Andreasen, Peter ; Overgaard, Jens.

    I: Lung Cancer, Vol. 56, Nr. 1, 2007, s. 43-50.

    Publikation: Forskning - peer review › Tidsskriftartikel

  50. Udgivet

    Urokinase-type plasminogen activator-inhibiting cyclic peptides demonstrate new modalities for inhibition of serine proteases. / Andersen, L.M. ; Wind, Troels ; Hansen, H.D. ; Blouse, Grant ; Christensen, A. ; Jensen, J.K. ; Malmendal, Anders ; Nielsen, Niels Christian ; Andreasen, Peter.

    2007. Poster session presented at XIth International Workshop on Molecular and Cellular Biology of Plasminogen Activation, Stockholm, Sverige.

    Publikation: Forskning › Poster

  51. 2006
  52. Udgivet

    Binding areas of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex for endocytosis receptors of the low-density lipoprotein receptor family, determined by site-directed mutagenesis. / Skeldal, Sune ; Larsen, Jakob Vejby ; Pedersen, Katrine E ; Petersen, Helle H ; Egelund, Rikke ; Christensen, Anni ; Jensen, Jan Kristian ; Gliemann, Jørgen ; Andreasen, Peter A.

    I: F E B S Journal, Vol. 273, Nr. 22, 01.11.2006, s. 5143-59.

    Publikation: Forskning - peer review › Tidsskriftartikel

  53. Udgivet

    Inhibition of plasminogen activator inhibitor-1 binding to endocytosis receptors of the low-density-lipoprotein receptor family by a peptide isolated from a phage display library. / Jensen, Jan Kristian ; Malmendal, Anders ; Schiøtt, Birgit ; Skeldal, Sune ; Pedersen, Katrine E ; Celik, Leyla ; Nielsen, Niels Chr. ; Andreasen, Peter A ; Wind, Troels.

    I: Biochemical Journal, Vol. 399, Nr. 3, 01.11.2006, s. 387-96.

    Publikation: Forskning - peer review › Tidsskriftartikel

  54. Udgivet

    Evidence for a pre-latent form of the serpin plasminogen activator inhibitor-1 with a detached beta-strand 1C. / Dupont, Daniel M ; Blouse, Grant E ; Hansen, Martin ; Mathiasen, Lisa ; Kjelgaard, Signe ; Jensen, Jan Kristian ; Christensen, Anni ; Gils, Ann ; Declerck, Paul J ; Andreasen, Peter A ; Wind, Troels.

    I: Journal of Biological Chemistry, Vol. 281, Nr. 47, 24.11.2006, s. 36071-81.

    Publikation: Forskning - peer review › Tidsskriftartikel

  55. Udgivet

    Binding areas of Urokinase-type plasminogen activator inhibitor-1 complex for endocytosis receptors of the low density lipoprotein receptor family, determined by site-directed mutagenesis. / Skeldal, Sune ; Larsen, J.V. ; Pedersen, K.E. ; Petersen, H.H. ; Egelund, R. ; Christensen, Anni ; Jensen, J.K. ; Gliemann, Jørgen ; Andreasen, Peter.

    2006. Poster session presented at Annual Meeting of the " Cancer Degradome", København, Danmark.

    Publikation: Forskning › Poster

  56. Udgivet

    Binding areas of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex for endocytosis receptors of the low density lipoprotein receptor family, determined by site-directed mutagenesis. / Skeldal, Sune ; Larsen, J. V. ; Pedersen, K. E. ; Petersen, H. H. ; Egelund, R. ; Christensen, A. ; Jensen, J. K. ; Gliemann, Jørgen ; Andreasen, Peter.

    I: FEBS J., Vol. 273, 2006, s. 5143-5159.

    Publikation: Forskning - peer review › Tidsskriftartikel

  57. Udgivet

    CpG methylation of the PAI-1 gene 5´-flanking region and the expression level of PAI-1 mRNA levels in oral squamous cell carcinomas. / Gao, Shan ; Krogdahl, A. ; Nielsen, B.S. ; Sørensen, J.A. ; Dabelsteen, E. ; Andreasen, Peter.

    2006. Poster session presented at Annual Meeting og the "Cancer Degradome", København, Danmark.

    Publikation: Forskning › Poster

  58. Udgivet

    Crystal structure of human urokinase complexed with a cyclic peptidyl inhibitor, upain-1. / Zhao, Gengxiang ; Yuan, Cai ; Bian, Chuanbing ; Hou, Xiaomin ; Rao, Yijian ; Wind, Troels ; Andreasen, Peter ; Ye, Xiaoming ; Huang, Zixiang ; Huang, Mingdong.

    2006. Poster session presented at Gordon Research Conference on Plasminogen Activation and Extracellular Proteolysis, Ventura, Californien, USA.

    Publikation: Forskning › Poster

  59. Udgivet

    Evidence for a prelatent form of plasminogen activator inhibitor-1 with a detached β-strand 1C. / Dupont, Daniel Miotto ; Blouse, Grant ; Hansen, Martin ; Mathiasen, Lisa ; Kristiansen, Signe Kjelgaard ; Jensen, J.K. ; Christensen, Anni ; Gils, A. ; Declerck, P.J. ; Andreasen, Peter ; Wind, Troels.

    I: Journal of Biological Chemistry, Vol. 281, 2006, s. 36071-36081.

    Publikation: Forskning - peer review › Tidsskriftartikel

  60. Udgivet

    Inhibition of plasminogen activator inhibitor-1 binding to endocytosis receptors of the low density lipoprotein receptor family by a peptide isolated from a phage displayed library. / Jensen, Jan K. ; Malmendal, Anders ; Schiøtt, Birgit ; Skeldal, Sune ; Pedersen, Katrine E. ; Celik, Leyla ; Nielsen, Niels Christian ; Andreasen, Peter ; Wind, Troels.

    I: Biochem. J., Vol. 399, 2006, s. 387-396.

    Publikation: Forskning - peer review › Tidsskriftartikel

  61. Udgivet

    Novel conformational probes and activity regulators of plasminogen avtivator inhibitor-1, isolated from phage-displayed disulfide bridge constrained peptide libraries. / Dupont, Daniel Miotto ; Hansen, Martin ; Jensen, J.K. ; Kristiansen, Signe Kjelgaard ; Mathiasen, Lisa ; Pedersen, K.E. ; Skeldal, Sune ; Wind, Troels ; Malmendal, Anders ; Schiøtt, Birgit ; Nielsen, Niels Christian ; Andreasen, Peter.

    2006. Poster session presented at Annual Meeting of the "Cancer Degradome", København, Danmark.

    Publikation: Forskning › Poster

  62. Udgivet

    Overexpression of protease nexin-1 mRNA in oral squamous cell carcinomas. / Gao, Shan ; Krogdahl, A. ; Sørensen, J.A. ; Dabelsteen, E. ; Andreasen, Peter.

    2006. Poster session presented at Annual Meeting of the "Cancer Degradome", København, Danmark.

    Publikation: Forskning › Poster

  63. 2005
  64. Udgivet

    A novel pesticide-induced conformational state of the oestrogen receptor ligand-binding domain, detected by conformation-specific peptide binding. / Sumbayev, Vadim V. ; Bonefeld-Jørgensen, Eva ; Wind, Troels ; Andreasen, Peter.

    I: F E B S Letters, Vol. 579, Nr. 2, 2005, s. 541-8.

    Publikation: Forskning - peer review › Tidsskriftartikel

  65. Udgivet

    A urokinase-type plasminogen activator-inhibiting cyclic peptide with an unusual P2 residue and an extended protease binding surface demonstrates new modalities for enzyme inhibition. / Hansen, M. ; Wind, Troels ; Blouse, Grant ; Christensen, Anni ; Petersen, H.H. ; Kjelgaard, S. ; Mathiasen, L. ; Holtet, T.L. ; Andreasen, Peter.

    I: Journal of Biological Chemistry, Vol. 280, 2005, s. 38424-38437.

    Publikation: Forskning - peer review › Tidsskriftartikel

  66. Udgivet

    Additivity in effects of vitronectin and monoclonal antibodies against a-helix F of plasminogen activator inhibitor-1 on its reaction with target proteinases. / Komissarov, A.A. ; Andreasen, Peter ; Bødker, Julie Støve ; Declerck, P.J. ; Anagli, J.Y. ; Shore, J.D..

    I: Journal of Biological Chemistry, Vol. 280, 2005, s. 1482-1489.

    Publikation: Forskning - peer review › Tidsskriftartikel

  67. Udgivet

    Cantilever sensor for nanomechanical detection of specific protein conformations. / Mukhopadhyay, Rupa ; Sumbayev, Vadim V. ; Kjems, Jørgen ; Andreasen, Peter ; Besenbacher, Flemming.

    I: Nano Lett., Vol. 5, 2005, s. 2385-2388.

    Publikation: Forskning - peer review › Tidsskriftartikel

  68. Udgivet

    Cantilever sensor for nanomechanical detection of specific protein conformations. / Mukhopadhyay, Rupa ; Sumbayev, Vadim V ; Lorentzen, Martin ; Kjems, Jørgen ; Andreasen, Peter A ; Besenbacher, Flemming.

    I: Nano Letters, Vol. 5, Nr. 12, 2005, s. 2385-8.

    Publikation: Forskning - peer review › Tidsskriftartikel

  69. Udgivet

    CpG methylation of the PAI-1 gene 5’ flanking region is inversely correlated with PAI-1 mRNA levels in human cell lines. / Gao, Shan ; Skeldal, Sune ; Krogdahll, A. ; Sørensen, J.A. ; Andreasen, Peter.

    I: Thromb. Haemostas., Vol. 94, 2005, s. 651-660.

    Publikation: Forskning - peer review › Tidsskriftartikel

  70. Udgivet

    Expression of urokinase plasminogen activator, its receptor and type-1 inhibitor in benign and malignant prostatic tissue. / Usher, P.A. ; Thomsen, O.F. ; Iversen, P. ; Johnsen, M. ; Brünner, N. ; Høyer-Hansen, G. ; Andreasen, Peter ; Danø, K. ; Nielsen, B.S..

    I: J. Cancer, Vol. 113, 2005, s. 870-880.

    Publikation: Forskning - peer review › Tidsskriftartikel

  71. Udgivet

    Synthesis of a hydroxyethylene isostere of the tripeptide Arg-Gly-Leu via a convergent acyl-like radical addition strategy. / Jensen, C.M. ; Lindsay, K.D. ; Andreasen, Peter ; Skrydstrup, Troels.

    I: J. Org. Chem., Vol. 70, 2005, s. 7512-7519.

    Publikation: Forskning - peer review › Tidsskriftartikel

  72. 2004
  73. Udgivet

    Construction of a plasminogen activator inhibitor-1 variant without measurable affinity to vitronection buth otherwise normal. / Jensen, J.K. ; Durand, M.K.V. ; Skeldal, S. ; Dupont, D.M. ; Bødker, J.S. ; Wind, T. ; Andreasen, Peter.

    I: F E B S Letters, Vol. 556, 2004, s. 175-179.

    Publikation: Forskning - peer review › Tidsskriftartikel

  74. Udgivet

    Leading edge myofibroblasts in human colon cancer express PAI-1. / Illemann, M. ; Hansen, U. ; Nielsen, H.F. ; Andreasen, Peter ; Høyer-Hansen, G..

    I: Am. J. Clin. Pathol., Vol. 122, 2004, s. 256-265.

    Publikation: Forskning - peer review › Tidsskriftartikel

  75. Udgivet

    The mosaic receptor sorLA/LR11 binds components of the plasminogen activating system and PDGF-BB similarity to low density lipoprotein receptor-related protein (LRP1) but mediates slow internalization of bound. / Gliemann, J. ; Hermey, G. ; Nykjær, Anders ; Petersen, C.M. ; Jacobsen, C. ; Andreasen, Peter.

    I: Biochem. J., Vol. 381, 2004, s. 203-212.

    Publikation: Forskning - peer review › Tidsskriftartikel

  76. Udgivet

    The mosaic receptor sorLA/LR11 binds components of the plasminogen-activating system and platelet-growth factor-BB similarly to LRP1 (low-density lipoprotein receptor-related protein), but mediates slow internalization of bound ligand.. / Gliemann, Jørgen ; Hermey, G. ; Nykjær, Anders ; Pedersen, Jens Claus Munck ; Jacobsen, Christian ; Andreasen, Peter Andre.

    I: Biochem. J., Vol. 381, 2004, s. 203-212.

    Publikation: Forskning - peer review › Tidsskriftartikel

  77. 2003
  78. Udgivet

    Biochemical mechanism of action of a diketopiperazine inactivator of plasminogen activator inhibitor-1.. / Einholm, Anja P ; Pedersen, Katrine E ; Wind, Troels ; Kulig, Paulina ; Overgaard, Michael T ; Jensen, Jan K ; Bødker, Julie S ; Christensen, Anni ; Charlton, Peter ; Andreasen, Peter A.

    I: Biochemical Journal, Vol. 373, Nr. Pt 3, 2003, s. 723-32.

    Publikation: Forskning - peer review › Tidsskriftartikel

  79. Udgivet

    Plasminogen activator inhibitor-1 polymers, induced by inactivating amphipathic organochemical ligands.. / Pedersen, Katrine E ; Einholm, Anja P ; Christensen, Anni ; Schack, Lotte ; Wind, Troels ; Kenney, John M ; Andreasen, Peter A.

    I: Biochemical Journal, Vol. 372, Nr. Pt 3, 2003, s. 747-55.

    Publikation: Forskning - peer review › Tidsskriftartikel

  80. Udgivet

    The myofibroblast is the predominant plasminogen activator inhibitor-1 expressing cell type in human breast carcinomas. / Offersen, B.V. ; Nielsen, B.S. ; Høyer-Hansen, G. ; Rank, F. ; Hamilton-Dutoit, S. ; Overgaard, J. ; Andreasen, Peter.

    I: American Journal of Pathology, Vol. 163, 2003, s. 1887-1899.

    Publikation: Forskning - peer review › Tidsskriftartikel

  81. Udgivet

    The pro-urokinase-plasminogen activation system in the presence of plasminogen activator inhibitor-1 and soluble urokinase receptor: Rescue of activity through reciprocal pro-enzyme activation. / Behrendt, N. ; List, K. ; Andreasen, Peter ; Danø, K..

    I: Biochem. J., Vol. 371, 2003, s. 277-287.

    Publikation: Forskning - peer review › Tidsskriftartikel

  82. Udgivet

    Vitronectin in human breast carcinomas. / Aaboe, M. ; Offersen, B.V. ; Christensen, A. ; Andreasen, Peter.

    I: Biochim. Biophys. Acta., Vol. 1638, 2003, s. 72-82.

    Publikation: Forskning › Tidsskriftartikel

  83. 2001
  84. Udgivet

    A regulatory hydrophobic area in the flexible joint region of plasminogen activator inhibitor-1, defined with fluorescent activity-neutralizing ligands. Ligand-induced serpin polymerization.. / Egelund, R ; Einholm, A P ; Pedersen, K E ; Nielsen, R W ; Christensen, A ; Deinum, J ; Andreasen, Peter A.

    I: Journal of Biological Chemistry, Vol. 276, Nr. 16, 2001, s. 13077-86.

    Publikation: Forskning - peer review › Tidsskriftartikel

  85. Udgivet

    Analysis of a two-domain binding site for the urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex in low density lipoprotein receptor-related protein. / Andersen, O.M. ; Petersen, H.H. ; Jacobsen, Christian ; Moestrup, Søren Kragh ; Etzerodt, M. ; Andreasen, Peter ; Thøgersen, H.C..

    I: Biochem. J., Vol. 357, 2001, s. 289-296.

    Publikation: Forskning - peer review › Tidsskriftartikel

  86. 2000
  87. Udgivet

    The plasminogen activation system. / Andreasen, Peter.

    I: Embryonic Encyclopedia of Life Sciences. London : Macmillan Publishers Limited, 2000. s. -.

    Publikation: Forskning › Bidrag til bog/antologi

  88. Udgivet

    The plasminogen activation system in tumor growth, invasion and metastasis. / Andreasen, Peter ; Egelund, R. ; Petersen, H.H..

    I: Cell. Mol. Life Sci., Vol. 57, 2000, s. 25-40.

    Publikation: Forskning - peer review › Tidsskriftartikel

  89. Udgivet

    Vitronectin and substitution of β-strand 5A residue Lys325 potentiate activity-neutralization of plasminogen activator inhibitor-1 by monoclonal antibodies against the α-helix F region. / Schousboe, S.L. ; Egelund, R. ; Kirkegaard, T. ; Preissner, K.T. ; Rodenburg, K.W. ; Andreasen, Peter.

    I: Thromb. Haemostas., Vol. 83, 2000, s. 742-751.

    Publikation: Forskning › Tidsskriftartikel

  90. 1999
  91. Udgivet

    ELISA for complexes of urokinase-type and tissue-type plasminogen activators with their type-1 inhibitor (uPA-PAI-1 and tPA-PAI-1). / Grebentschikov, N. ; Sweep, F. ; Geurts, A. ; Andreasen, Peter ; de Witte, H. ; Schousboe, S.L. ; Heuvel, J. ; Benraad, T..

    I: International Journal of Cancer, Vol. 81, 1999, s. 598-606.

    Publikation: Forskning - peer review › Tidsskriftartikel

  92. Udgivet

    Engineering of conformations of plasminogen activator inhibitor-1. A crucial role of β-strand 5A residues in the transition of active form to latent and substrate forms. / Kirkegaard, T. ; Jensen, S. ; Schousboe, S.L. ; Petersen, H.H. ; Egelund, R. ; Andreasen, Peter ; Rodenburg, K.W..

    I: F E B S Journal, Vol. 263, 1999, s. 577-586.

    Publikation: Forskning › Tidsskriftartikel

  93. Udgivet

    Ligand binding properties of the very low density lipoprotein receptor. Absence of the third complement-type repeat encoded by exon 4 is associated with reduced binding of Mr 40,000 receptor-associated. / Rettenberger, P.M. ; Oka, K. ; Ellgaard, L. ; Petersen, H.H. ; Christensen, A. ; Martensen, P.M. ; Monard, D. ; Etzerodt, M. ; Chan, L. ; Andreasen, Peter.

    I: Journal of Biological Chemistry, Vol. 274, 1999, s. 8973-8980.

    Publikation: Forskning - peer review › Tidsskriftartikel

  94. Udgivet

    Solvent effects on activity and conformation of plasminogen activator inhibitor-1. / Andreasen, Peter ; Egelund, R. ; Jensen, S. ; Rodenburg, K.W..

    I: Thromb. Haemostas., Vol. 81, 1999, s. 407-414.

    Publikation: Forskning - peer review › Tidsskriftartikel

  95. 1997
  96. Udgivet

    Binding of plasminogen and tissue-type plasminogen activator to dimeric αs2-casein accelerates plasmin generation. / Heegaard, Christian Wurtz ; Andreasen, Peter ; Petersen, Torben E. ; Rasmussen, Lone K..

    I: Fibrinolysis & proteolysis, Vol. 11, 1997, s. 29-36.

    Publikation: Forskning - peer review › Tidsskriftartikel

  97. Udgivet

    Breast carcinoma epithelial cells express a very low density lipoprotein receptor variant lacking the O-linked glycosylation domain encoded by exon 16, but with full binding activity for serine proteinase/serpin complex and Mr 40,000 receptor associated protein. / Martensen, Pia Møller ; kazuhiro, Oka ; Rettenberger, Peter M. ; Petersen, Helle H. ; Christensen, Anni ; Lawrence, Chang ; Heegaard, Christian Wurtz ; Andreasen, Peter.

    I: F E B S Journal, Vol. 248, 1997, s. 583-591.

    Publikation: Forskning - peer review › Tidsskriftartikel

  98. Udgivet

    Dimeric alphas2-casein, a novel matrix for tissue-type plasminogen activator catalyzed plasminogen activation. / Heegaard, Christian Wurtz ; Andreasen, Peter ; Petersen, Torben Ellebæk ; Rasmussen, Lone K..

    I: Livestock Science, Nr. 1-2, 1997, s. 149.

    Publikation: Forskning - peer review › Konferenceartikel

  99. Udgivet

    Specificity of serine proteinase/serpin complex binding to very low density lipoprotein receptor and α2-macroglobulin receptor /LDL-receptor-related protein. / Kasza, Aneta ; Petersen, Helle H. ; Heegaard, Christian Wurtz ; Oka, Kazuhiro ; Christensen, Anni ; Dubin, Adam ; Chan, Lawrence ; Andreasen, Peter.

    I: F E B S Journal, Vol. 248, 1997, s. 270-281.

    Publikation: Forskning - peer review › Tidsskriftartikel

  100. Udgivet

    The plasminogen activation system in human milk. / Heegaard, Christian Wurtz ; Larsen, Lotte Bach ; Rasmussen, Lone K. ; Højberg, Karen-Elise ; Petersen, Torben E. ; Andreasen, Peter.

    I: Journal of Pediatric Gastroenterology and Nutrition, Vol. 25, 1997, s. 159-166.

    Publikation: Forskning - peer review › Tidsskriftartikel

  101. 1996
  102. Udgivet

    Immunohistochemical localization of urokinase‑type plasminogen activator, type‑1 plasminogen activator inhibitor, urokinase receptor and alpha(2)‑macroglobulin receptor in human breast carcinomas. / Christensen, Lise ; Wiborg Simonsen, Anna Carina ; Heegaard, Christian Wurtz ; Moestrup, Søren Kragh ; Andersen, Johan A. ; Andreasen, Peter.

    I: International Journal of Cancer, Vol. 66, 1996, s. 441-452.

    Publikation: Forskning - peer review › Tidsskriftartikel

  103. 1995
  104. Udgivet

    Very low density lipoprotein receptor binds and mediates endocytosis of urokinase-type plasminogen activator-type-1 plasminogen activator inhibitor complex. / Heegaard, Christian Wurtz ; Wiborg Simonsen, Anna Carina ; Oka, Kazuhiro ; Kjøller, Lars ; Christensen, Anni ; Madsen, Bente ; Ellgaard, Lars ; Chan, Lawrence ; Andreasen, Peter.

    I: Journal of Biological Chemistry, Vol. 270, 1995.

    Publikation: Forskning - peer review › Tidsskriftartikel

  105. 1994
  106. Udgivet

    Plasminogen activators in bovine milk during mastitis, an inflammatory disease. / Heegaard, Christian Wurtz ; Christensen, Tove ; Rasmussen, Morten Dam ; Benfeldt, Connie ; Einer-Jensen, Niels ; Sejrsen, Kristen ; Petersen, Torben E. ; Andreasen, Peter.

    I: Fibrinolysis & proteolysis, Vol. 8, 1994, s. 22-30.

    Publikation: Forskning - peer review › Tidsskriftartikel

  107. Udgivet

    The multiligand α2-macroglobulin receptor/low density lipoprotein receptor-related protein. / Gliemann, Jørgen ; Nykjær, Anders ; Petersen, Claus Munck ; Jørgensen, K.E. ; Andreasen, Peter ; Christensen, Erik Ilsø ; Moestrup, Søren Kragh.

    I: New York Academy of Sciences. Annals, Vol. 737, 1994, s. 20-38.

    Publikation: Forskning › Review

  108. Udgivet

    The plasminogen activation system in bovine milk: differential localization of tissue‑type plasminogen activator and urokinase in milk fractions is caused by binding to casein and urokinase receptor. / Heegaard, Christian Wurtz ; K. Rasmussen, Lone ; Andreasen, Peter.

    I: B B A - Molecular Cell Research, Vol. 1222, 1994, s. 45-55.

    Publikation: Forskning - peer review › Tidsskriftartikel

  109. Udgivet

    The α2-macroglobulin receptor/low density lipoprotein receptor-related protein. Binding and endocytosis of fluid-phase and membrane-associated ligands. / Gliemann, Jørgen ; Nykjær, Anders ; Petersen, Claus Munck ; Jørgensen, K. E. ; Nielsen, Morten Schallburg ; Andreasen, Peter ; Christensen, Erik Ilsø ; Lookene, A. ; Olivecrona, G. ; Moestrup, Søren Kragh.

    I: Ann. N. Y. Acad. Sci., Vol. 737, 1994, s. 20-38.

    Publikation: Forskning - peer review › Tidsskriftartikel

  110. Udgivet

    Very low density lipoprotein receptor from mammary gland and mammary epithelial cell lines binds and mediates endocytosis of M(r) 40,000 receptor associated protein. / Wiborg Simonsen, Anna Carina ; Heegaard, Christian Wurtz ; Rasmussen, Lone K. ; Ellgaard, Lars ; Kjøller, Lars ; Christensen, Anni ; Etzerodt, Michael ; Andreasen, Peter.

    I: F E B S Letters, Vol. 354, 1994, s. 279-283.

    Publikation: Forskning - peer review › Tidsskriftartikel

  111. 1993
  112. Udgivet

    Epithelial glycoprotein-330 mediates endocytosis of plasminogen activator-plasminogen activator inhibitor type-1 complexes. / Moestrup, S K ; Nielsen, Susanne ; Andreasen, P ; Jørgensen, K E ; Nykjaer, A ; Røigaard, H ; Gliemann, J ; Christensen, E I.

    I: Journal of Biological Chemistry, Vol. 268, Nr. 22, 05.08.1993, s. 16564-16570.

    Publikation: Forskning - peer review › Tidsskriftartikel

  113. Udgivet

    Alpha 2-macroglobulin-proteinase complexes, plasminogen activator inhibitor type-1-plasminogen activator complexes, and receptor-associated protein bind to a region of the alpha(2)-Macroglobulin receptor containing a cluster of eight complement-type repeats. / Moestrup, Søren Kragh ; Holtet, Thor L. ; Etzerodt, Michael ; Thøgersen, Hans Christian ; Nykjær, Anders ; Andreasen, Peter ; Rasmussen, H.H. ; Sottrup-Jensen, Lars ; Gliemann, Jørgen.

    I: Journal of Biological Chemistry, Vol. 268, Nr. 18, 1993, s. 13691-13696.

    Publikation: Forskning - peer review › Tidsskriftartikel

  114. Udgivet

    Interconversions between active, inert and substrate forms of denatured/refolded type‑1 plasminogen activator inhibitor. / Munch, Mette ; Heegaard, Christian Wurtz ; Andreasen, Peter.

    I: B B A - Proteins and Proteomics, Vol. 1202, 1993, s. 29-37.

    Publikation: Forskning - peer review › Tidsskriftartikel

  115. 1992
  116. Udgivet

    Purified alpha(2)-Macroglobulin receptor/LDL receptor-related protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha(2)-Macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes. / Nykjær, Anders ; Petersen, Claus Munck ; Møller, B. ; Jensen, Poul Henning ; Moestrup, Søren Kragh ; Holtet, Thor L. ; Etzerodt, Michael ; Thøgersen, Hans Christian ; Munch, Mette ; Andreasen, Peter ; Gliemann, Jørgen.

    I: Journal of Biological Chemistry, Vol. 267, Nr. 21, 1992, s. 14543-14546.

    Publikation: Forskning - peer review › Tidsskriftartikel

  117. 1991
  118. Udgivet

    Type‑1 inhibitor of plasminogen activators. Distinction between latent, activated and reactive center‑cleaved forms with thermal stability and monoclonal antibodies. / Munch, Mette ; Heegaard, Christian Wurtz ; Jensen, Poul Henning ; Andreasen, Peter.

    I: F E B S Letters, Vol. 295, 1991, s. 102-106.

    Publikation: Forskning - peer review › Tidsskriftartikel

  119. 1990
  120. Udgivet

    Lysosomal degradation of receptor-bound urokinase-type plasminogen activator is enhanced by its inhibitors in human trophoblastic choriocarcinoma cells. / Jensen, Poul Henning ; Christensen, Erik Ilsø ; Ebbesen, P. ; Gliemann, Jørgen ; Andreasen, Peter A..

    I: Cell regulation, Vol. 13, 1990, s. 1043-1056.

    Publikation: Forskning - peer review › Tidsskriftartikel