32 peer reviewed publikationer (13 som 1 forfatter og 7 som sidste forfatter 1 kapitet i bog,1 patent
Risk factor SORL1: from genetic association to functional validation in Alzheimer's disease
Andersen, O. M., Rudolph, I-M. & Willnow, T. E. 16 sep. 2016 I : Acta Neuropathologica. 132, 5, s. 653–665 9 s.SorCS2 is required for BDNF-dependent plasticity in the hippocampus
Glerup, S., Bolcho, U., Bøggild, S., Vaegter, C. B., Smith, A. H., Nieto-Gonzalez, J. L., Ovesen, P. L., Pedersen, L. F., Fjorback, A. N., Kjolby, M., Login, H., Holm, M. M., Andersen, O. M., Nyengaard, J. R., Willnow, T. E., Jensen, K., Nykjaer, A. & Jensen, S. M. 2016 I : Molecular Psychiatry.The A-B-C for SORting APP
Coulson, E. J. & Andersen, O. M. okt. 2015 I : Journal of Neurochemistry. 135, 1, s. 1-3 3 s.Mutants of Metal Binding Site M1 in APP E2 Show Metal Specific Differences in Binding of Heparin but Not of sorLA
Dienemann, C., Coburger, I., Mehmedbasic, A., Andersen, O. M. & Than, M. E. 10 apr. 2015 I : Biochemistry.SorLA CR-Domains Protect the Amyloid Precursor Protein against Processing
Mehmedbasic, A., Christensen, S. K., Nilsson, J., Rüetschi, U., Gustafsen, C., Poulsen, A. S. A., Rasmussen, R. W., Fjorback, A. N., Larson, G. & Andersen, O. M. 18 dec. 2014 I : Journal of Biological Chemistry.New Horizons for Lipoprotein ReceptorsCommunication by β-propellers
Andersen, O. M., Dagil, R. & Kragelund, B. B. okt. 2013 I : Journal of Lipid Research. 54(10), s. 2763- 2774 11 s.Sorting receptor SORLA - a trafficking path to avoid Alzheimer disease
Willnow, T. E. & Andersen, O. M. 1 jul. 2013 I : Journal of Cell Science. 126, Pt 13, s. 2751-60 10 s.Sortilin and SorLA Display Distinct Roles in Processing and Trafficking of Amyloid Precursor Protein
Gustafsen, C., Glerup, S., Pallesen, L. T., Olsen, D., Andersen, O. M., Nykjær, A., Madsen, P. & Petersen, C. M. 2013 I : Journal of Neuroscience. 33, 1, s. 64-71 8 s.SorLA is a molecular link for retromer-dependent sorting of the Amyloid precursor protein
Fjorback, A. W. & Andersen, O. M. 1 nov. 2012 I : Communicative & Integrative Biology. 5, 6, s. 616-9 4 s.Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing
Fjorback, A. W., Seaman, M., Gustafsen, C., Mehmedbasic, A., Gokool, S., Wu, C., Militz, D., Schmidt, V., Madsen, P., Nyengaard, J. R., E Willnow, T., Christensen, E. I., B Mobley, W., Nykjær, A. & Andersen, O. M. 2012 I : Journal of Neuroscience. 32, 4, s. 1467-1480 14 s.APP involvement in retinogenesis of mice
Dinet, V., An, N., Ciccotosto, G. D., Bruban, J., Maoui, A., Bellingham, S. A., Hill, A. F., Andersen, O. M., Nykjaer, A., Jonet, L., Cappai, R. & Mascarelli, F. 1 mar. 2011 I : Acta Neuropathologica. 121, 3, s. 351-63 13 s.The structure of MESD45-184 brings light into the mechanism of LDLR family folding
Köhler, C., Lighthouse, J. K., Werther, T., Andersen, O. M., Diehl, A., Schmieder, P., Du, J., Holdener, B. C. & Oschkinat, H. 2011 I : Structure. 19, 3, s. 337-48 12 s.Identification of a linear epitope in sortilin that partakes in pro-neurotropin binding
Andersen, O. S., Boisguerin, P., Glerup, S., Skeldal, S., Volkmer, R., Wilnow, T. E., Nykjær, A. & Andersen, O. M. 2010 I : Journal of Biological Chemistry. s. 12210-12222 22 s.Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export.
Kjølby, M. F., Andersen, O. M., Breiderhoff, T., Fjorback, A. N., Pedersen, K-M., Madsen, P. S., Jansen, P., Heeren, J., Willnow, T. & Nykjær, A. 2010 I : Cell Metabolism. 12, 3, s. 213-223 11 s.Interaction of the Apolipoprotein E Receptors low-density lipoprotein receptor related protein and sorLA/LR11
Spoelgen, R., Adams, K. W., Koker, M., Thomas, A. V., Andersen, O. M., Hallet, P. J., Bercury, K. K., Joyner, D. F., Deng, M., Stoothoff, W. H., Strickland, D. K., Willnow, T. E. & Hyman, B. T. 2009 I : Journal of Neuroscience. 158, s. 1460-1468 8 s.Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: Evidence for a proximal role in Alzheimer's disease
Dodson, S. E., Andersen, O. M., Karmali, V., Fritz, J. J., Cheng, D., Peng, J., Levey, A. I., Wilnow, T. E. & Lah, J. J. 2008 I : The Journal of neuroscience : the official journal of the Society for Neuroscience. 28, s. 12877-12886 9 s.Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependant stimulation of ERK signalling and adult neurogenesis
Rohe, M., Carlo, A. S., Breyhan, H., Sporbert, A., Millitz, D., Schmidt, V., Wozny, C., Harmeier, A., Erdmann, B., Bales, K. R., Wolf, S., Kempermann, G., Paul, S. M., Schmitz, D., Bayer, T. A., Wilnow, T. E. & Andersen, O. M. 2008 I : Journal of Biological Chemistry. J. Biol Chem, 283, s. 14826-14834 8 s.Localization of the low-density lipoprotein receptor-related protein regions involved in binding to the A2 domain of coagulation factor VIII.
Sarafanov, A. G., Makagonenko, E. M., Andersen, O., Mikhailenko, I. A., Ananyeva, N. M., Khrenov, A. V., Shima, M., Strickland, D. K. & Saenko, E. L. 2007 I : Thromb. Haemost.. 98, s. 1170-1181 12 s.SorLA/LR11 regulates processing of the amyloid precursor protein via interactions with adaptors GGA and PACS-1.
Schmidt, V., Sporbert, A., Rohe, M., Reimer, T., Rehm, A., Andersen, O. & Wilnow, T. E. 2007 I : Journal of Biological Chemistry. 282, s. 32956-32964 9 s.The solution structure of the core of mesoderm development (MESD), a chaperone for members of the LDLR-family.
Köhler, C., Andersen, O., Diehl, A., Krause, G., Schmieder, P. & Oschkinat, H. 2007 I : J. Struct. Funct. Genom.. 7, s. 131-138 8 s.Binding site structure of one LRP/RAP complex - Implications for common ligand-receptor binding motif.
Jensen, G. A., Andersen, O., Bonvin, A. M., Bjerrum-Bohr, I., Etzerodt, M., Thøgersen, H. C., O'Shea, B., Poulsen, F. M. & Kragelund, B. B. 2006 I : J. Mol. Biol.. 362, s. 700-716 17 s.Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein and β-secretase, BACE.
Spoelgen, R., Peltan, I. D., Thomas, A. V., Koker, M., von Armin, C. A. F., Deng, A., Andersen, O., Willnow, T. E. & Hyman, B. T. 2006 I : The Journal of neuroscience : the official journal of the Society for Neuroscience. 45, 8, s. 2618-2628 11 s.Molecular Dissection of the Interaction Between Amyloid Precursor Protein and Its Neuronal Trafficking Receptor SorLA/LR11.
Andersen, O., Schmidt, V., Spoelgen, R., Gliemann, J., Behlke, J., Galatis, D., McKinstry, W. J., Parker, M. W., Masters, C. L., Hyman, B. T., Cappai, R. & Wilnow, T. E. 2006 I : Biochemistry. 45, 8, s. 2618-2628 11 s.The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer's Disease.
Rogaeva, E., Meng, Y., Lee, J. H., Gu, Y., Kawarai, T., Zou, F., Katayama, T., Baldwin, C. T., Cheng, R., Hasegawa, H., Chen, F., Shíbata, N., Lunetta, K. L., Pardossi-Piquard, R., Bohm, C., Wakutani, Y., Cupples, L. A., Kuenco, K. T., Green, R. C., Pinessi, L., Rainero, I., Sorbi, S., Bruni, A., Duara, R., Friedland, R., Inzelberg, R., Hampe, W., Bujo, H., Song, Y., Andersen, O., Wilnow, T. E., Graff-Redford, N., Petersen, R. C., Dickson, D., Der, S. D., Fraser, P. E., Ulms, G., Younkin, S., Mayeux, R., Farrer, L. A. & St George-Hyslop, P. 2006 I : Nat. Genet.. 39, s. 168-177 10 s.LRP2/Megalin is required for patterning of the ventral telencephalon.
Spoelgen, R., Hammes, A., Anzenberger, U., Sechner, D., Andersen, O., Jerchow, B. & Wilnov, T. E. 2005 I : Developement. 132, s. 405-414 9 s.Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
Andersen, O., Reiche, J., Schmidt, V., Gotthardt, M., Spoelgen, R., Behlke, J., Arnim, C. A. V., Breiderhoff, T., Jansen, P., Wu, X., Bales, K. R., Cappai, R., Masters, C. L., Gliemann, J., Mufson, E. J., Hyman, B. T., Paul, S. M., Nykjær, A. & Wilnow, T. E. 2005 I : National Academy of Sciences. Proceedings. s. 13461-13466 5 s.Ca2+ binding to complement-type repeat domains 5 and 6 from the low density lipoprotein receptor-related protein.
Andersen, O., Vorum, H., Honoré, B. & Thøgersen, H. C. 2003 I : B M C Biochemistry. 4, 1, s. 7-7 1 s.Differential binding of ligands to the Apolipoprotein E Receptor 2.
Andersen, O., Benhayon, D., Curran, T. & Willnov, T. E. 2003 I : Biochemistry. 42, s. 9355-9364 9 s.Essential Role of the Apolipoprotein E Receptor-2 in Sperm Development.
Andersen, O., Yeung, C. H., Vorum, H., Wellner, M., Andreassen, T. K., Erdmann, B., Mueller, E. C., Herz, J., Otto, A., Cooper, T. G. & Willnov, T. E. 2003 I : Journal of Biological Chemistry. 278, s. 23989-23995 7 s.Analysis of a two-domain binding site for the urokinase-type plasminogen activator - plasminogen activator inhibitor-1 complex in low density lipoprotein receptor-related protein,
Andersen, O., Petersen, H. H., Jacobsen, C., Moestrup, S. K., Etzerodt, M., Andreasen, P. & Thøgersen, H. C. 2001 I : Biochem. J.. 357, s. 289-296 8 s.Dominant thermodynamic role of the third independent receptor binding site in the receptor-associated protein RAP.
Andersen, O., Schwarz, F. P., Eisenstein, E., Jacobsen, C., Moestrup, S. K., Etzerodt, M. & Thøgersen, H. C. 2001 I : Biochemistry. 40, s. 15408-15417 10 s.Identification of the minimal functional unit in the low density lipoprotein receptor-related protein for binding the receptor-associated protein (RAP)
Christensen, L. L., Christensen, P. A., Sørensen, E. S., Jacobsen, C., Moestrup, S. K., Etzerodt, M., Thøgersen, H. & Andersen, O. 2000 I : Journal of Biological Chemistry. 275, 28, s. 21017-21024 8 s.Specific Binding of a-Macroglobulin to Complement-type Repeat CR4 of the Low Density Lipoprotein Receptor-related Protein.
Andersen, O., Christensen, P. A., Christensen, L. L., Jacobsen, C., Moestrup, S. K., Etzerodt, M. & Thøgersen, H. C. 2000 I : Biochemistry. 39, 35, s. 10627-10633 7 s.
