Antiprotons for Radiobiology and Cancer Therapy, the AD-4/ACE Experiment. / Holzscheiter, Michael ; Alsner, Jan ; Angelopoulos, A. ; Bassler, Niels ; Curell, Fred ; Doser, M. ; Herrmann, Rochus ; Jäkel , Oliver ; Kaiser, Franz-Joachim ; Kantemiris , I. ; Kavanagh , J. ; Keyes, Roy ; Knudsen, Helge ; Overgaard, Jens ; Petersen, Jørgen B.B. ; Schettino , G. ; Sellner, Stefan ; Sørensen, Brita Singers ; Tegami, Sarah ; Timson , D. ; Tölli , Heikki.

Publikation: Forskning › Konferenceabstrakt i tidsskrift

Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck. / Toustrup, Kasper ; Sørensen, Brita Singers ; Lassen, Pernille ; Wiuf, Carsten ; Alsner, Jan ; Overgaard, Jens ; Danish Head and Neck Cancer Group (DAHANCA).

Publikation: Forskning - peer review › Tidsskriftartikel

Mannan-binding lectin (MBL) and MBL-associated serine protease 2 (MASP-2) genotypes in colorectal cancer. / Ytting, H ; Christensen, I J ; Steffensen, Rudi Nora ; Alsner, Jan ; Thiel, Steffen ; Jensenius, Jens Christian ; Hansen, U ; Nielsen, H J.

Publikation: Forskning - peer review › Tidsskriftartikel

In vivo Identification and Specificity assessment of mRNA markers of hypoxia in human and mouse tumors. / Busk, Morten ; Toustrup, Kasper ; Soerensen, Brita S ; Alsner, Jan ; Horsman, Michael R ; Jakobsen, Steen ; Overgaard, Jens.

Publikation: Forskning - peer review › Tidsskriftartikel

Development of a hypoxia gene expression classifier with predictive impact for hypoxic modification of radiotherapy in head and neck cancer. / Toustrup, Kasper ; Sørensen, Brita Singers ; Nordsmark, Marianne ; Busk, Morten ; Wiuf, Carsten ; Alsner, Jan ; Overgaard, Jens.

Publikation: Forskning - peer review › Tidsskriftartikel

Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer. / Gonzalez-Angulo, Ana M ; Hennessy, Bryan T ; Meric-Bernstam, Funda ; Sahin, Aysegul ; Liu, Wenbin ; Ju, Zhenlin ; Carey, Mark S ; Myhre, Simen ; Speers, Corey ; Deng, Lei ; Broaddus, Russell ; Lluch, Ana ; Aparicio, Sam ; Brown, Powel ; Pusztai, Lajos ; Symmans, W Fraser ; Alsner, Jan ; Overgaard, Jens ; Børresen-Dale, Anne-Lise ; Hortobagyi, Gabriel N ; Coombes, Kevin R ; Mills, Gordon B.

Publikation: Forskning - peer review › Tidsskriftartikel

In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome. / Myhre, Simen ; Mohammed, Hayat ; Tramm, Trine ; Alsner, Jan ; Finak, Greg ; Park, Morag ; Overgaard, Jens ; Børresen-Dale, Anne-Lise ; Frigessi, Arnoldo ; Sørlie, Therese.

Publikation: Forskning - peer review › Tidsskriftartikel

Establishment of a Radiogenomics Consortium. / West, Catharine ; Rosenstein, Barry S ; Alsner, Jan ; Azria, David ; Barnett, Gillian ; Begg, Adrian ; Bentzen, Søren ; Burnet, Neil ; Chang-Claude, Jenny ; Chuang, Eric ; Coles, Charlotte ; De Ruyck, Kim ; De Ruysscher, Dirk ; Dunning, Alison ; Elliott, Rebecca ; Fachal, Laura ; Hall, Janet ; Haustermans, Karin ; Herskind, Carsten ; Hoelscher, Tobias ; Imai, Takashi ; Iwakawa, Mayumi ; Jones, Don ; Kulich, Cecilia ; Langendijk, Jan-Hans ; O'Neils, Peter ; Ozsahin, Mahmut ; Parliament, Matthew ; Polanski, Andrzej ; Rosenstein, Barry ; Seminara, Daniela ; Symonds, Paul ; Talbot, Chris ; Thierens, Hubert ; Vega, Ana ; West, Catharine ; Yarnold, John ; EQUAL-ESTRO.

Publikation: Forskning › Tidsskriftartikel

Intraperitoneal administration of chitosan/DsiRNA nanoparticles targeting TNFα prevents radiation-induced fibrosis. / Nawroth, Isabel ; Alsner, Jan ; Behlke, Mark A ; Besenbacher, Flemming ; Overgaard, Jens ; Howard, Kenneth A ; Kjems, Jørgen.

Publikation: Forskning - peer review › Tidsskriftartikel

A technical assessment of the utility of Reverse Phase Protein Arrays for the study of the functional proteome in non-microdissected human breast cancers. / Hennessy, Bryan T ; Lu, Yiling ; Gonzalez-Angulo, Ana Maria ; Carey, Mark S ; Myhre, Simen ; Ju, Zhenlin ; Davies, Michael A ; Liu, Wenbin ; Coombes, Kevin ; Meric-Bernstam, Funda ; Bedrosian, Isabelle ; McGahren, Mollianne ; Agarwal, Roshan ; Zhang, Fan ; Overgaard, Jens ; Alsner, Jan ; Neve, Richard M ; Kuo, Wen-Lin ; Gray, Joe W ; Børresen-Dale, Anne-Lise ; Mills, Gordon B.

Publikation: Forskning - peer review › Tidsskriftartikel

Biodistribution of 99mTc-HYNIC-lactadherin in mice - a potential tracer for visualizing apoptosis in vivo. / Falborg, Lise ; Waehrens, Lasse N ; Alsner, Jan ; Bluhme, Henrik ; Frøkiaer, Jørgen ; Heegaard, Christian W ; Horsman, Michael R ; Rasmussen, Jan T ; Rehling, Michael.

Publikation: Forskning - peer review › Tidsskriftartikel

HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer. / Lassen, P. ; Eriksen, J.G. ; Hamilton-Dutoit, S. ; Tramm, T. ; Alsner, J. ; Overgaard, J..

Publikation: Forskning - peer review › Tidsskriftartikel

Identifying pH independent hypoxia induced genes in human squamous cell carcinomas in vitro. / Sørensen, Brita Singers ; Toustrup, Kasper ; Horsman, Michael Robert ; Overgaard, Jens ; Alsner, Jan.

Publikation: Forskning - peer review › Tidsskriftartikel

Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck. / Lassen, Pernille ; Eriksen, Jesper G ; Hamilton-Dutoit, Stephen ; Tramm, Trine ; Alsner, Jan ; Overgaard, Jens.

Publikation: Forskning - peer review › Tidsskriftartikel

Expression of EGFR and HPV-associated p16 in head and neck cancer: correlation and influence on prognosis after radiotherapy in 1088 patients from the randomised DAHANCA 5, 6 & 7 trials.. / Lassen, Pernille ; Eriksen, Jesper Grau ; Tramm, Trine ; Hamilton-Dutoit, Stephen Jacques ; Alsner, Jan ; Overgaard, Jens.

Publikation: Forskning › Konferenceabstrakt i tidsskrift

Genetic variants and normal tissue toxicity after radiotherapy: a systematic review. / Andreassen, Christian Nicolaj ; Alsner, Jan.

Publikation: Forskning - peer review › Tidsskriftartikel

Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer. / Agarwal, Roshan ; Gonzalez-Angulo, Ana-Maria ; Myhre, Simen ; Carey, Mark ; Lee, Ju-Seog ; Overgaard, Jens ; Alsner, Jan ; Stemke-Hale, Katherine ; Lluch, Ana ; Neve, Richard M ; Kuo, Wen Lin ; Sorlie, Therese ; Sahin, Aysegul ; Valero, Vicente ; Keyomarsi, Khandan ; Gray, Joe W ; Børresen-Dale, Anne-Lise ; Mills, Gordon B ; Hennessy, Bryan T.

Publikation: Forskning - peer review › Tidsskriftartikel

Proteins upregulated by mild and severe hypoxia in squamous cell carcinomas in vitro identified by proteomics. / Sørensen, Brita Singers ; Horsman, Michael R ; Vorum, Henrik ; Honoré, Bent ; Overgaard, Jens ; Alsner, Jan.

Publikation: Forskning - peer review › Tidsskriftartikel

A comparison among HER2, TP53, PAI-1, angiogenesis, and proliferation activity as prognostic variables in tumours from 408 patients diagnosed with early breast cancer. / Offersen, Birgitte Vrou ; Alsner, Jan ; Ege Olsen, Karen ; Riisbro, Rikke ; Brünner, Nils ; Sørensen, Flemming Brandt ; Sørensen, Boe Sandahl ; Schlemmer, Birgitte Olrik ; Overgaard, Jens.

Publikation: Forskning - peer review › Tidsskriftartikel

A comparison between p53 accumulation determined by immunohistochemistry and TP53 mutations as prognostic variables in tumours from breast cancer patients.. / Alsner, Jan ; Jensen, Vibeke ; Kyndi, Marianne ; Offersen, Birgitte Vrou ; Vu, Phuong ; Børresen-Dale, Anne-Lise ; Overgaard, Jens.

Publikation: Forskning - peer review › Tidsskriftartikel

Antiproton Radiotherapy : (invited paper). / Bassler, Niels ; Alsner, Jan ; Beyer, Gerd ; DeMarco, John J, ; Doser, Michael ; Hajdukovic, Dragan ; Hartley, Oliver ; Iwamoto, Keisuke S. ; Jäkel, Oliver ; Knudsen, Helge ; Kovacevic, Sandra ; Møller, Søren Pape ; Overgaard, Jens ; Petersen, Jørgen B.B. ; Solberg, Timothy D. ; Sørensen, Brita Singers ; Vranjes, Sanja ; Wouters, Bradly G. ; Holzscheiter, Michael H..

Publikation: Forskning - peer review › Konferenceartikel

Antiproton therapy. / Knudsen, Helge ; Holzscheiter, Michael H. ; Bassler, Niels ; Alsner, Jan ; Beyer, Gerd ; DeMarco, John J. ; Doser, Michael ; Hajdukovic, Dragan ; Hartley, Oliver ; Iwamoto, Keisuke S. ; Jäkel, Oliver ; Kovacevic, Sandra ; Møller, Søren Pape ; Overgaard, Jens ; Petersen, Jørgen B.B. ; Ratib, Osman ; Solberg, Timothy D. ; Vranjes, Sanja ; Wouters, Bradly G..

Publikation: Forskning - peer review › Tidsskriftartikel

Carbonic anhydrase IX and response to postmastectomy radiotherapy in high-risk breast cancer: a subgroup analysis of the DBCG82 b and c trials. / Kyndi, Marianne ; Sørensen, Flemming B ; Knudsen, Helle ; Alsner, Jan ; Overgaard, Marie ; Nielsen, Hanne M ; Overgaard, Jens ; Danish Breast Cancer Cooperative Group.

Publikation: Forskning - peer review › Tidsskriftartikel

Genetic markers for prediction of normal tissue toxicity after radiotherapy. / Alsner, Jan ; Andreassen, Christian Nicolaj ; Overgaard, Jens.

Publikation: Forskning - peer review › Tidsskriftartikel

Impact of BCL2 and p53 on postmastectomy radiotherapy response in high-risk breast cancer. A subgroup analysis of DBCG82 b&c.. / Kyndi, M ; Sørensen, Flemming Brandt ; Knudsen, Helle ; Alsner, J ; Overgaard, M ; Nielsen, Hanne Melgaard ; Overgaard, Jens.

Publikation: Forskning - peer review › Tidsskriftartikel

Radiation-induced gene expression in human subcutaneous fibroblasts is predictive of radiation-induced fibrosis. / Rødningen, Olaug Kristin ; Børresen-Dale, Anne-Lise ; Alsner, Jan ; Hastie, Trevor ; Overgaard, Jens.

Publikation: Forskning - peer review › Tidsskriftartikel

The impact of hypoxia on the activity of lactate dehydrogenase in two different pre-clinical tumour models.. / Lukacova, Slavka ; Sørensen, Brita ; Alsner, Jan ; Overgaard, Jens ; Horsman, Michael.

Publikation: Forskning - peer review › Tidsskriftartikel

Transformation of human mesenchymal stem cells in radiation carcinogenesis: long-term effect of ionizing radiation. / Christensen, Rikke ; Alsner, Jan ; Brandt Sorensen, Flemming ; Dagnaes-Hansen, Frederik ; Kolvraa, Steen ; Serakinci, Nedime.

Publikation: Forskning - peer review › Tidsskriftartikel

Biodistribution and tracer kinetics in small and large animals of 99mTc-HYNIC-lactadherin compared to 99mTc-HYNIC-annexin V. / Falborg, Lise ; Wæhrens, Lasse Neumann ; Alsner, Jan ; Dissing, Thomas Heide ; Eilersen, J ; Frøkiær, Jørgen ; Heegaard, Christian Wurtz ; Horsman, Michael Robert ; Rasmussen, Jan Trige ; Nielsen, Søren Steen ; Rehling, Michael.

Publikation: Forskning › Konferenceabstrakt i tidsskrift

Differential gene expression before and after ionizing radiation of subcutaneous fibroblasts identifies breast cancer patients resistant to radiation-induced fibrosis. / Alsner, Jan ; Rødningen, Olaug K. ; Overgaard, Jens.

Publikation: Forskning - peer review › Tidsskriftartikel

Differential risk assessments from five hypoxia specific assays: The basis for biologically adapted individualized radiotherapy in advanced head and neck cancer patients. / Nordsmark, Marianne ; Eriksen, Jesper Grau ; Gebski, Val ; Alsner, Jan ; Horsman, Michael Robert ; Overgaard, Jens.

Publikation: Forskning - peer review › Tidsskriftartikel

Ectopically hTERT expressing adult human mesenchymal stem cells are less radiosensitive than their telomerase negative counterpart.. / Serakinci, Nedime ; Christensen, Rikke ; Graakjaer, Jesper ; Cairney, Claire J ; Keith, W Nicol ; Alsner, Jan ; Saretzki, Gabriele ; Kolvraa, Steen ; Christensen, Rikke.

Publikation: Forskning - peer review › Tidsskriftartikel

Hypoxia induced expression of endogenous markers in vitro is highly influenced by pH. / Sørensen, Brita Singers ; Alsner, Jan ; Overgaard, Jens ; Horsman, Michael Robert.

Publikation: Forskning - peer review › Tidsskriftartikel

Reproductive death of cancer cells induced by femtosecond laser pulses. / Thøgersen, Jan ; Knudsen, Cindy S. ; Maetzke, Alice ; Jensen, Svend Knak ; Keiding, Søren Rud ; Alsner, Jan ; Overgaard, Jens.

Publikation: Forskning - peer review › Tidsskriftartikel

ATM sequence variants and risk of radiation-induced subcutaneous fibrosis after postmastectomy radiotherapy. / Andreassen, Christian Nicolaj ; Overgaard, Jens ; Alsner, Jan ; Overgaard, Marie ; Herskind, Carsten ; Cesaretti, Jamie A ; Atencio, David P ; Green, Sheryl ; Formenti, Silvia C ; Stock, Richard G ; Rosenstein, Barry S.

Publikation: Forskning - peer review › Tidsskriftartikel

Focal S100A4 protein expression is an independent predictor of development of metastatic disease in cystectomized bladder cancer patients. / Agerbæk, Mads ; Alsner, Jan ; Marcussen, Niels ; Lundbeck, Finn ; Maase, Hans von der.

Publikation: Forskning - peer review › Tidsskriftartikel

LOH rather than genotypes of TP53 codon 72 is associated with disease-free survival in primary breast cancer. / Kyndi, Marianne ; Alsner, Jan ; Hansen, Lise Lotte ; Sørensen, Flemming Brandt ; Overgaard, Jens.

Publikation: Forskning - peer review › Tidsskriftartikel

Risk of radiation-induced subcutaneous fibrosis in relation to single nucleotide polymorphisms in TGFB1, SOD2, XRCC1, XRCC3, APEX and ATM - a study based on DNA from formalin fixed paraffin embedded tissue samples. / Andreassen, Christian Nicolaj ; Alsner, Jan ; Overgaard, Marie ; Sørensen, Flemming Brandt ; Overgaard, Jens.

Publikation: Forskning - peer review › Tidsskriftartikel

Strain and tumour specific variations in the effect of hypoxia on osteopontin levels in experimental models. / Lukácová, Slávka ; Overgaard, Jens ; Alsner, Jan ; Horsman, Michael Robert.

Publikation: Forskning - peer review › Tidsskriftartikel

TGFB1 polymorphisms are associated with risk of late normal tissue complications in the breast after radiotherapy for early breast cancer. / Andreassen, Christian Nicolaj ; Alsner, Jan ; Overgaard, Jens ; Herskind, Carsten ; Haviland, Jo ; Owen, Roger ; Homewood, Janis ; Bliss, Judith ; Yarnold, John.

Publikation: Forskning - peer review › Tidsskriftartikel

Influence of oxygen concentration and pH on expression of hypoxia induced genes. / Sørensen, Brita Singers ; Hao, J. ; Overgaard, J. ; Vorum, Henrik ; Honore, Bent ; Alsner, J. ; Horsman, M.R..

Publikation: Forskning - peer review › Tidsskriftartikel

Microarray analysis of the transcriptional response to single or multiple doses of ionizing radiation in human subcutaneous fibroblasts. / Rødningen, Olaug Kristin ; Overgaard, Jens ; Alsner, Jan ; Hastie, Trevor ; Børresen-Dale, Anne-Lise.

Publikation: Forskning - peer review › Tidsskriftartikel

Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: : Results from the DAHANCA 5 randomised double-blind placebo-controlled trial. / Overgaard, J. ; Eriksen, Jesper Grau ; Nordsmark, Marianne ; Alsner, J. ; Horsman, M.R..

Publikation: Forskning - peer review › Tidsskriftartikel

Relationship between radiobiological hypoxia in a C3H mouse mammary carcinoma and osteopontin levels in mouse serum. / Lukácová, Slávka ; Khalil, Azza Ahmed ; Overgaard, Jens ; Alsner, Jan ; Horsman, Michael Robert.

Publikation: Forskning - peer review › Tidsskriftartikel

The possible role of TP53 mutation status in the treatment of squamous cell carcinomas of the head and neck (HNSCC) with radiotherapy with different overall treatment times. / Eriksen, Jesper Grau ; Alsner, J. ; Steiniche, Torben ; Overgaard, J..

Publikation: Forskning - peer review › Tidsskriftartikel

Molecular profiles as predictive marker for the effect of overall treatment time of radiotherapy in supraglottic larynx squamous cell carcinomas. / Eriksen, J.G. ; Buffa, F.M. ; Alsner, J. ; Steiniche, T. ; Bentzen, S.M. ; Overgaard, J..

Publikation: Forskning › Tidsskriftartikel

Optimisation and validation of methods to assess single nucleotide polymorphisms (SNPs) in archival histological material. / Andreassen, C.N. ; Sørensen, F.B. ; Overgaard, J. ; Alsner, J..

Publikation: Forskning › Tidsskriftartikel

The prognostic value of epidermal growth factor receptor is related to tumor differentiation and the overall treatment time of radiotherapy in squamous cell carcinomas of the head and neck. / Eriksen, J.G. ; Steiniche, T. ; Askaa, J. ; Alsner, J. ; Overgaard, J..

Publikation: Forskning › Tidsskriftartikel

Prediction of normal tissue radiosensitivity from polymorphisms in candidate genes. / Andreassen, C.N. ; Alsner, J. ; Overgaard, M. ; Overgaard, J..

Publikation: Forskning › Tidsskriftartikel

Retinoblastoma protein expression is an independent predictor of both radiation response and survival in muscle-invasive bladder cancer. / Agerbæk, M. ; Alsner, J. ; Marcussen, N. ; Lundbeck, F. ; von der Maase, H..

Publikation: Forskning › Tidsskriftartikel

Spatial evolutionary games of interactions among generic cancer cells.. / Bach, Lars ; Sumpter, David ; Alsner, Jan ; Loeschcke, Volker.

Publikation: Forskning - peer review › Tidsskriftartikel

Does variability in normal tissue reactions after radiotherapy have a genetic basis - where and how to look for it. / Andreassen, C.N. ; Alsner, J. ; Overgaard, J..

Publikation: Forskning › Tidsskriftartikel

Interaction between potential doubling time and TP53 mutation: predicting radiotherapy outcome in squamous cell carcinoma of the head and neck. / Alsner, J ; Høyer, M ; Sørensen, S B ; Overgaard, J.

Publikation: Forskning - peer review › Tidsskriftartikel

An evolutionary-game model of tumour-cell interactions: possible relevance to gene therapy. / Bach, L.A. ; Bentzen, S.M. ; Alsner, J. ; Christiansen, F.B..

Publikation: Forskning › Tidsskriftartikel

Hypoxia in human soft tissue sarcomas: Adverse impact on survival and no association with p53 mutations. / Nordsmark, M. ; Alsner, J. ; Keller, J. ; Nielsen, O.S. ; Jensen, O.M. ; Horsman, M.R. ; Overgaard, J..

Publikation: Forskning › Tidsskriftartikel

Hypoxia in human soft tissue sarcomas: adverse impact on survival and no association with p53 mutations. / Nordsmark, M ; Alsner, J ; Keller, Johnny ; Nielsen, Ole Steen ; Jensen, O M ; Horsman, M R ; Overgaard, J.

Publikation: Forskning - peer review › Tidsskriftartikel

Interaction between potential doubling time and TP53 mutation: predicting radiotherapy outcome in squamous cell carcinoma of the head and neck. / Alsner, J. ; Høyer, M. ; Sørensen, S.B. ; Overgaard, J..

Publikation: Forskning › Tidsskriftartikel

TP53 mutation is related to poor prognosis after radiotherapy, but not surgery, in squamous cell carcinoma of the head and neck. / Alsner, J. ; Sørensen, S.B. ; Overgaard, J..

Publikation: Forskning › Tidsskriftartikel

Hypoxia in human soft tissue sarcomas. Adverse impact on survival and no association with p53 mutations.. / Nordsmark, Marianne ; Alsner, Jan ; Keller, Johnny Østergaard ; Nielsen, Ole Steen ; Jensen, O. M. ; Overgaard, Jens.

Publikation: Forskning - peer review › Konferenceabstrakt i tidsskrift

Importance of overall treatment time for the response to radiotherapy in patients with squamous cell carcinoma of the head and neck. / Overgaard, J ; Alsner, J ; Eriksen, J ; Horsman, M R ; Grau, Cai.

Publikation: Forskning - peer review › Tidsskriftartikel