Jan Alsner

  1. 2017
  2. Udgivet
  3. 2016
  4. Udgivet

    HPV status, cancer stem cell marker expression, hypoxia gene signatures and tumour volume identify good prognosis subgroups in patients with HNSCC after primary radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG). / Linge, Annett; Lohaus, Fabian; Löck, Steffen; Nowak, Alexander; Gudziol, Volker; Valentini, Chiara; von Neubeck, Cläre; Jütz, Martin; Tinhofer, Inge; Budach, Volker; Sak, Ali; Stuschke, Martin; Balermpas, Panagiotis; Rödel, Claus; Grosu, Anca-Ligia; Abdollahi, Amir; Debus, Jürgen; Ganswindt, Ute; Belka, Claus; Pigorsch, Steffi; Combs, Stephanie E; Mönnich, David; Zips, Daniel; Buchholz, Frank; Aust, Daniela E; Baretton, Gustavo B; Thames, Howard D; Dubrovska, Anna; Alsner, Jan; Overgaard, Jens; Krause, Mechthild; Baumann, Michael; DKTK-ROG.

    I: Radiotherapy & Oncology, Bind 121, Nr. 3, 12.2016, s. 364-373.

    Publikation: Forskning - peer reviewTidsskriftartikel

  5. Udgivet

    Radiation-induced morbidity evaluated by high-frequency ultrasound. / Schack, Line M Hybel; Alsner, Jan; Overgaard, Jens; Andreassen, Christian Nicolaj; Offersen, Birgitte V.

    I: Acta Oncologica, Bind 55, Nr. 12, 12.2016, s. 1498-1500.

    Publikation: Forskning - peer reviewTidsskriftartikel

  6. Udgivet

    The relative biological effectiveness of antiprotons. / Holzscheiter, Michael H.; Alsner, Jan; Bassler, Niels; Boll, Rebecca; Caccia, Massimo; Knudsen, Helge; Maggiore, Carl; Petersen, Jørgen B.; Sellner, Stefan; Strasse, Tina; Sørensen, Brita Singers; Overgaard, Jens.

    I: Radiotherapy & Oncology, Bind 121, Nr. 3, 12.2016, s. 453-458.

    Publikation: Forskning - peer reviewTidsskriftartikel

  7. Udgivet

    Establishment and characterisation of oropharyngeal cancer patient-derived xenografts as a model for radiation research. / Lilja-Fischer, Jacob Kinggaard; Ulhøi, Benedicte Parm; Alsner, Jan; Lassen, Pernille; Nielsen, Viveque Egsgaard; Overgaard, Jens.

    2016. Poster session præsenteret ved International symposium on HPV infection in head and neck cancer, Leipzig, Tyskland.

    Publikation: Forskning - peer reviewPoster

  8. Udgivet
  9. Udgivet

    An evaluation of multiplex bead-based analysis of cytokines and soluble proteins in archived lithium heparin plasma, EDTA plasma and serum samples. / Brøndum, Line; Sørensen, Brita Singers; Eriksen, Jesper Grau; Mortensen, Lise Saksø; Lønbro, Simon; Overgaard, Jens; Alsner, Jan.

    I: Scandinavian Journal of Clinical & Laboratory Investigation, Bind 76, Nr. 8, 26.09.2016, s. 601-611.

    Publikation: Forskning - peer reviewTidsskriftartikel

  10. Udgivet

    Radiogenomics - current status, challenges and future directions. / Andreassen, Christian Nicolaj; Schack, Line Meinertz Hybel; Laursen, Louise Vagner; Alsner, Jan.

    I: Cancer Letters, Bind 382, Nr. 1, 01.09.2016, s. 127-136.

    Publikation: ForskningReview

  11. Udgivet

    Integrative Analysis of DCE-MRI and Gene Expression Profiles in Construction of a Gene Classifier for Assessment of Hypoxia-Related Risk of Chemoradiotherapy Failure in Cervical Cancer. / Fjeldbo, Christina S; Julin, Cathinka H; Lando, Malin; Forsberg, Malin F; Aarnes, Eva-Katrine; Alsner, Jan; Kristensen, Gunnar B; Malinen, Eirik; Lyng, Heidi.

    I: Clinical Cancer Research, Bind 22, Nr. 16, 15.08.2016, s. 4067-76.

    Publikation: Forskning - peer reviewTidsskriftartikel

  12. Udgivet

    Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients. / Andreassen, Christian Nicolaj; Rosenstein, Barry S; Kerns, Sarah L; Ostrer, Harry; De Ruysscher, Dirk; Cesaretti, Jamie A; Barnett, Gillian C; Dunning, Alison M; Dorling, Leila; West, Catharine M L; Burnet, Neil G; Elliott, Rebecca; Coles, Charlotte; Hall, Emma; Fachal, Laura; Vega, Ana; Gómez-Caamaño, Antonio; Talbot, Christopher J; Symonds, R Paul; De Ruyck, Kim; Thierens, Hubert; Ost, Piet; Chang-Claude, Jenny; Seibold, Petra; Popanda, Odilia; Overgaard, Marie; Dearnaley, David; Sydes, Matthew R; Azria, David; Koch, Christine Anne; Parliament, Matthew; Blackshaw, Michael; Sia, Michael; Fuentes-Raspall, Maria J; Ramon Y Cajal, Teresa; Barnadas, Agustin; Vesprini, Danny; Gutiérrez-Enríquez, Sara; Mollà, Meritxell; Díez, Orland; Yarnold, John R; Overgaard, Jens; Bentzen, Søren M; Alsner, Jan; International Radiogenomics Consortium (RgC).

    I: Radiotherapy & Oncology, 18.07.2016.

    Publikation: Forskning - peer reviewTidsskriftartikel

  13. Udgivet
  14. Udgivet

    Low Cancer Stem Cell Marker Expression and Low Hypoxia Identify Good Prognosis Subgroups in HPV(-) HNSCC after Postoperative Radiochemotherapy: A Multicenter Study of the DKTK-ROG. / Linge, Annett; Löck, Steffen; Gudziol, Volker; Nowak, Alexander; Lohaus, Fabian; von Neubeck, Cläre; Jütz, Martin; Abdollahi, Amir; Debus, Jürgen; Tinhofer, Inge; Budach, Volker; Sak, Ali; Stuschke, Martin; Balermpas, Panagiotis; Rödel, Claus; Avlar, Melanie; Grosu, Anca-Ligia; Bayer, Christine; Belka, Claus; Pigorsch, Steffi; Combs, Stephanie E; Welz, Stefan; Zips, Daniel; Buchholz, Frank; Aust, Daniela E; Baretton, Gustavo B; Thames, Howard D; Dubrovska, Anna; Alsner, Jan; Overgaard, Jens; Baumann, Michael; Krause, Mechthild; DKTK-ROG.

    I: Clinical Cancer Research, Bind 22, Nr. 11, 01.06.2016, s. 2639-49.

    Publikation: Forskning - peer reviewTidsskriftartikel

  15. Udgivet
  16. Udgivet

    Prognostic value of hypoxia-regulated gene expression in loco-regional gastroesophageal cancer. / Winther, Mette; Alsner, Jan; Tramm, Trine; Holtved, E; Baeksgaard, L; Nordsmark, Marianne.

    I: Acta Oncologica, Bind 55, Nr. 5, 05.2016, s. 652-5.

    Publikation: Forskning - peer reviewTidsskriftartikel

  17. Udgivet
  18. Udgivet

    Gene-expression Classifier in Papillary Thyroid Carcinoma: Validation and Application of a Classifier for Prognostication. / Londero, Stefano Christian; Jespersen, Marie Louise; Krogdahl, Annelise; Bastholt, Lars; Overgaard, Jens; Schytte, Sten; Godballe, Christian; Alsner, Jan; The Danish Thyroid Cancer Group – DATHYRCA (part of the DAHANCA organization).

    I: Anticancer Research, Bind 36, Nr. 2, 02.2016, s. 749-56.

    Publikation: Forskning - peer reviewTidsskriftartikel

  19. Udgivet

    Hypoxia-regulated microRNAs in gastroesophageal cancer. / Winther, Mette; Alsner, Jan; Sørensen, Brita Singers; Wittrup, Catja Foged; Tramm, Trine; Beaksgaard, L; Hofland, K; Holtved, E; Nordsmark, Marianne.

    I: Anticancer Research, Bind 36, Nr. 2, 02.2016, s. 721-30.

    Publikation: Forskning - peer reviewTidsskriftartikel

  20. Udgivet

    Clinical Impact of a Novel MicroRNA Chemo-Sensitivity Predictor in Gastrooesophageal Cancer. / Winther, Mette; Knudsen, Steen; Dahlgaard, Jesper; Jensen, Thomas; Hansen, Anker; Jensen, Peter Buhl; Tramm, Trine; Alsner, Jan; Nordsmark, Marianne.

    I: P L o S One, Bind 11, Nr. 2, e0148070, 2016.

    Publikation: Forskning - peer reviewTidsskriftartikel

  21. 2015
  22. Udgivet
  23. Udgivet

    Danish retinoblastoma patients 1943-2013 - genetic testing and clinical implications. / Gregersen, Pernille A; Urbak, Steen F; Funding, Mikkel; Overgaard, Jens; Jensen, Uffe B; Alsner, Jan.

    I: Acta Oncologica, 23.10.2015, s. 1-6.

    Publikation: Forskning - peer reviewTidsskriftartikel

  24. Udgivet

    Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium. / Pettersen, Erik O; Ebbesen, Peter; Gieling, Roben G; Williams, Kaye J; Dubois, Ludwig; Lambin, Philippe; Ward, Carol; Meehan, James; Kunkler, Ian H; Langdon, Simon P; Ree, Anne H; Flatmark, Kjersti; Lyng, Heidi; Calzada, Maria J; Peso, Luis Del; Landazuri, Manuel O; Görlach, Agnes; Flamm, Hubert; Kieninger, Jochen; Urban, Gerald; Weltin, Andreas; Singleton, Dean C; Haider, Syed; Buffa, Francesca M; Harris, Adrian L; Scozzafava, Andrea; Supuran, Claudiu T; Moser, Isabella; Jobst, Gerhard; Busk, Morten; Toustrup, Kasper; Overgaard, Jens; Alsner, Jan; Pouyssegur, Jacques; Chiche, Johanna; Mazure, Nathalie; Marchiq, Ibtissam; Parks, Scott; Ahmed, Afshan; Ashcroft, Margaret; Pastorekova, Silvia; Cao, Yihai; Rouschop, Kasper M; Wouters, Brad G; Koritzinsky, Marianne; Mujcic, Hilda; Cojocari, Dan.

    I: Journal of Enzyme Inhibition and Medicinal Chemistry, 10.2015, s. 689-721.

    Publikation: Forskning - peer reviewReview

  25. Udgivet

    Dose-response modifiers in radiation therapy. / Horsman, Michael Robert; Lindegaard, Jacob Christian; Grau, Cai; Nordsmark, Marianne; Alsner, Jan; Overgaard, Jens.

    Clinical radiation oncology. red. / LL Gundersen; JE Tepper. 4. udg. Philadelphia, PA, USA : Elsevier Science, 2015. s. 51-62.

    Publikation: ForskningBidrag til bog/antologi

  26. Udgivet
  27. Udgivet
  28. Udgivet

    Evaluation of miR-21 and miR-375 as prognostic biomarkers in esophageal cancer. / Winther, Mette; Alsner, Jan; Tramm, Trine; Baeksgaard, Lene; Holtved, Eva; Nordsmark, Marianne.

    I: Acta oncologica (Stockholm, Sweden), Bind 54, Nr. 9, 2015, s. 1582-91.

    Publikation: Forskning - peer reviewTidsskriftartikel

  29. Udgivet

    Relative biological effectiveness of carbon ions for tumor control, acute skin damage and late radiation-induced fibrosis in a mouse model. / Sørensen, Brita Singers; Horsman, Michael Robert; Alsner, Jan; Overgaard, Jens; Durante, Marco; Scholz, Michael; Friedrich, Thomas; Bassler, Niels.

    I: Acta Oncologica, Bind 54, Nr. 9, 2015, s. 1623-1630.

    Publikation: Forskning - peer reviewTidsskriftartikel

  30. Udgivet
  31. 2014
  32. Udgivet
  33. Udgivet

    Effect of radiation on cell proliferation and tumor hypoxia in HPV-positive head and neck cancer in vivo models. / Sørensen, Brita Singers; Busk, Morten; Horsman, Michael R; Alsner, Jan; Overgaard, Jens; Kyle, Alastair H; Minchinton, Andrew I.

    I: Anticancer Research, Bind 34, Nr. 11, 11.2014, s. 6297-304.

    Publikation: Forskning - peer reviewTidsskriftartikel

  34. Udgivet

    Development and validation of a gene profile predicting benefit of postmastectomy radiotherapy in patients with high-risk breast cancer: a study of gene expression in the DBCG82bc cohort. / Tramm, Trine; Mohammed, Hayat; Myhre, Simen; Kyndi, Marianne; Alsner, Jan; Børresen-Dale, Anne-Lise; Sørlie, Therese; Frigessi, Arnoldo; Overgaard, Jens.

    I: Clinical Cancer Research, Bind 20, Nr. 20, 15.10.2014, s. 5272-80.

    Publikation: Forskning - peer reviewTidsskriftartikel

  35. Udgivet
  36. Udgivet

    Radiogenomics: radiobiology enters the era of big data and team science. / Rosenstein, Barry S; West, Catharine M; Bentzen, Søren M; Alsner, Jan; Andreassen, Christian Nicolaj; Azria, David; Barnett, Gillian C; Baumann, Michael; Burnet, Neil; Chang-Claude, Jenny; Chuang, Eric Y; Coles, Charlotte E; Dekker, Andre; De Ruyck, Kim; De Ruysscher, Dirk; Drumea, Karen; Dunning, Alison M; Easton, Douglas; Eeles, Rosalind; Fachal, Laura; Gutiérrez-Enríquez, Sara; Haustermans, Karin; Henríquez-Hernández, Luis Alberto; Imai, Takashi; Jones, George D D; Kerns, Sarah L; Liao, Zhongxing; Onel, Kenan; Ostrer, Harry; Parliament, Matthew; Pharoah, Paul D P; Rebbeck, Timothy R; Talbot, Christopher J; Thierens, Hubert; Vega, Ana; Witte, John S; Wong, Philip; Zenhausern, Frederic; International Radiogenomics Consortium.

    I: International Journal of Radiation: Oncology - Biology - Physics, Bind 89, Nr. 4, 15.07.2014, s. 709-13.

    Publikation: Forskning - peer reviewReview

  37. Udgivet

    Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c. / Nygren, M. K.; Tekle, C.; Ingebrigtsen, V. A.; Mäkelä, R.; Krohn, M.; Aure, M. R.; Nunes-Xavier, C. E.; Perälä, M.; Tramm, T.; Alsner, J.; Overgaard, J.; Nesland, J. M.; Borgen, E.; Børresen-Dale, A. L.; Fodstad, O.; Sahlberg, K. K.; Leivonen, S. K.

    I: B J C, Bind 110, Nr. 8, 01.01.2014, s. 2072-2080.

    Publikation: Forskning - peer reviewTidsskriftartikel

  38. Udgivet
  39. Udgivet

    Hypoxia and radiation therapy. / Nordsmark, Marianne; Alsner, Jan; Busk, Morten; Overgaard, Jens; Horsman, Michael Robert.

    Hypoxia and Cancer: Biological Implications and Therapeutic Opportunities. red. / Giovanni Melilo. New York : Humana Press, 2014. s. 265-81.

    Publikation: Forskning - peer reviewBidrag til bog/antologi

  40. 2013
  41. Udgivet

    Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection. / Tramm, Trine; Hennig, Guido; Kyndi, Marianne; Alsner, Jan; Sørensen, Flemming Brandt; Myhre, Simen; Sørlie, Therese; Overgaard, Jens.

    I: Virchows Archiv, Bind 463, Nr. 6, 12.2013, s. 775-786.

    Publikation: Forskning - peer reviewTidsskriftartikel

  42. Udgivet

    Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors. / Aure, Miriam Ragle; Leivonen, Suvi-Katri; Fleischer, Thomas; Zhu, Qian; Overgaard, Jens; Alsner, Jan; Tramm, Trine; Louhimo, Riku; Alnæs, Grethe I; Perälä, Merja; Busato, Florence; Touleimat, Nizar; Tost, Jörg; Børresen-Dale, Anne-Lise; Hautaniemi, Sampsa; Troyanskaya, Olga G; Lingjærde, Ole Christian; Sahlberg, Kristine Kleivi; Kristensen, Vessela N.

    I: Genome Biology, Bind 14, Nr. 11, R126, 20.11.2013.

    Publikation: Forskning - peer reviewTidsskriftartikel

  43. Udgivet

    Independent prospective validation of a predictive test for risk of radiation induced fibrosis based on the gene expression pattern in fibroblasts irradiated in vitro. / Andreassen, Christian Nicolaj; Overgaard, Jens; Alsner, Jan.

    I: Radiotherapy & Oncology, Bind 108, Nr. 3, 03.10.2013, s. 469-472.

    Publikation: Forskning - peer reviewTidsskriftartikel

  44. Udgivet

    Hypoxia-regulated gene expression and prognosis in loco-regional gastroesophageal cancer. / Winther, Mette; Alsner, Jan; Tramm, Trine; Nordsmark, Marianne.

    I: Acta Oncologica, Bind 52, Nr. 7, 10.2013, s. 1327-1335.

    Publikation: Forskning - peer reviewTidsskriftartikel

  45. Udgivet
  46. Udgivet

    Radiosensitivity and effect of hypoxia in HPV positive head and neck cancer cells. / Sørensen, Brita Singers; Busk, Morten; Olthof, Nadine; Speel, Ernst-Jan; Horsman, Michael R; Alsner, Jan; Overgaard, Jens.

    I: Radiotherapy & Oncology, Bind 108, Nr. 3, 13.08.2013, s. 500-505.

    Publikation: Forskning - peer reviewTidsskriftartikel

  47. Udgivet
  48. Udgivet

    SNP in TXNRD2 Associated With Radiation-Induced Fibrosis: A Study of Genetic Variation in Reactive Oxygen Species Metabolism and Signaling. / Edvardsen, Hege; Landmark-Høyvik, Hege; Reinertsen, Kristin V; Zhao, Xi; Grenaker-Alnæs, Grethe Irene; Nebdal, Daniel; Syvänen, Ann-Christine; Rødningen, Olaug; Alsner, Jan; Overgaard, Jens; Børresen-Dale, Anne-Lise; Fosså, Sophie D; Kristensen, Vessela N.

    I: International Journal of Radiation: Oncology - Biology - Physics, Bind 86, Nr. 4, 15.07.2013, s. 791-799.

    Publikation: Forskning - peer reviewTidsskriftartikel

  49. Udgivet

    Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins. / Myhre, Simen; Lingjærde, Ole-Christian; Hennessy, Bryan T; Aure, Miriam R; Carey, Mark S; Alsner, Jan; Tramm, Trine; Overgaard, Jens; Mills, Gordon B; Børresen-Dale, Anne-Lise; Sørlie, Therese.

    I: Molecular Oncology, Bind 7, Nr. 3, 06.2013, s. 704-18.

    Publikation: Forskning - peer reviewTidsskriftartikel

  50. Udgivet
  51. Udgivet

    Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection. / Tramm, Trine; Hennig, Guido; Kyndi, Marianne; Alsner, Jan; Sørensen, Flemming Brandt; Myhre, Simen; Sørlie, Therese; Overgaard, Jens.

    I: Virchows Archiv, Bind 463, Nr. 3, 2013, s. 775-786.

    Publikation: Forskning - peer reviewTidsskriftartikel

  52. Udgivet
  53. Udgivet
  54. 2012
  55. Udgivet
  56. Udgivet

    Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck. / Toustrup, Kasper; Sørensen, Brita Singers; Lassen, Pernille; Wiuf, Carsten; Alsner, Jan; Overgaard, Jens; Danish Head and Neck Cancer Group (DAHANCA).

    I: Radiotherapy & Oncology, Bind 102, Nr. 1, 01.2012, s. 122-129.

    Publikation: Forskning - peer reviewTidsskriftartikel

  57. Udgivet

    Antiprotons for Radiobiology and Cancer Therapy, the AD-4/ACE Experiment. / Holzscheiter, Michael; Alsner, Jan; Angelopoulos, A.; Bassler, Niels; Curell, Fred; Doser, M.; Herrmann, Rochus; Jäkel , Oliver; Kaiser, Franz-Joachim; Kantemiris , I.; Kavanagh , J.; Keyes, Roy; Knudsen, Helge; Overgaard, Jens; Petersen, Jørgen B.B.; Schettino , G.; Sellner, Stefan; Sørensen, Brita Singers; Tegami, Sarah; Timson , D.; Tölli , Heikki.

    I: Radiotherapy & Oncology, Bind 102, Nr. Supplement 1, 2012, s. S24-S25.

    Publikation: ForskningKonferenceabstrakt i tidsskrift

  58. Afsendt

    Breast irradiation profile. A gene expression signature predicting benefit of radiation therapy in breast cancer patients. / Alsner, Jan (Opfinder); Tramm, Trine (Opfinder); Børresen-Dale, Anne Lise (Opfinder); Frigessi, Arnoldo (Opfinder); Mohammed, Hayat (Opfinder); Myhre, Simen (Opfinder); Sørlie, Therese (Opfinder); Overgaard, Jens (Opfinder).

    IPC nr.: U.S. Provisional Patent Application Serial No. 61/607,316.

    Publikation: ForskningPatent

  59. Udgivet

    Conducting radiogenomic research--do not forget careful consideration of the clinical data. / Andreassen, Christian Nicolaj; Barnett, Gillian C; Langendijk, Johannes A; Alsner, Jan; De Ruysscher, Dirk; Krause, Mechtild; Bentzen, Søren M; Haviland, Joanne S; Griffin, Clare; Poortmans, Philip; Yarnold, John R.

    I: Radiotherapy & Oncology, Bind 105, Nr. 3, 2012, s. 337-40.

    Publikation: Forskning - peer reviewTidsskriftartikel

  60. Udgivet

    Hypoxia gene expression signatures as prognostic and predictive markers in head and neck radiotherapy. / Toustrup, Kasper; Sørensen, Brita S; Alsner, Jan; Overgaard, Jens.

    I: Seminars in Radiation Oncology, Bind 22, Nr. 2, 2012, s. 119-127.

    Publikation: Forskning - peer reviewTidsskriftartikel

  61. Udgivet

    Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity. / Barnett, Gillian C; Elliott, Rebecca M; Alsner, Jan; Andreassen, Christian N; Abdelhay, Osama; Burnet, Neil G; Chang-Claude, Jenny; Coles, Charlotte E; Gutiérrez-Enríquez, Sara; Fuentes-Raspall, Maria J; Alonso-Muñoz, Maria C; Kerns, Sarah; Raabe, Annette; Symonds, R Paul; Seibold, Petra; Talbot, Chris J; Wenz, Frederik; Wilkinson, Jennifer; Yarnold, John; Dunning, Alison M; Rosenstein, Barry S; West, Catharine M L; Bentzen, Søren M.

    I: Radiotherapy & Oncology, Bind 105, Nr. 3, 2012, s. 289-295.

    Publikation: Forskning - peer reviewTidsskriftartikel

  62. Udgivet

    Method for determining clinically relevant hypoxia in cancer. / Alsner, Jan (Opfinder); Toustrup, Kasper (Opfinder); Sørensen, Brita Singers (Opfinder); Wiuf, Carsten Henrik (Opfinder); Nordsmark, Marianne (Opfinder); Overgaard, Jens (Opfinder).

    IPC nr.: C12Q 1/68 (2006.01), A61K 31/415 (2006.01), A61K 31/4164 (2006.01) . Patentnummer: WO/2012/146259. nov. 01, 2012.

    Publikation: ForskningPatent

  63. 2011
  64. Udgivet
  65. Udgivet

    Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer. / Gonzalez-Angulo, Ana M; Hennessy, Bryan T; Meric-Bernstam, Funda; Sahin, Aysegul; Liu, Wenbin; Ju, Zhenlin; Carey, Mark S; Myhre, Simen; Speers, Corey; Deng, Lei; Broaddus, Russell; Lluch, Ana; Aparicio, Sam; Brown, Powel; Pusztai, Lajos; Symmans, W Fraser; Alsner, Jan; Overgaard, Jens; Børresen-Dale, Anne-Lise; Hortobagyi, Gabriel N; Coombes, Kevin R; Mills, Gordon B.

    I: Clinical Proteomics, Bind 8, Nr. 1, 08.07.2011, s. 11.

    Publikation: Forskning - peer reviewTidsskriftartikel

  66. Udgivet
  67. Udgivet

    Mannan-binding lectin (MBL) and MBL-associated serine protease 2 (MASP-2) genotypes in colorectal cancer. / Ytting, H; Christensen, I J; Steffensen, Rudi Nora; Alsner, Jan; Thiel, Steffen; Jensenius, Jens Christian; Hansen, U; Nielsen, H J.

    I: Scandinavian Journal of Immunology, Bind 73, Nr. 2, 01.02.2011, s. 122-7.

    Publikation: Forskning - peer reviewTidsskriftartikel

  68. Udgivet

    Status Report for Experiment AD-4/ACE. / Holzscheiter, Michael; Alsner, Jan; Angelopoulos, Angelo; Bassler, Niels; Beyer, Gerd; Boll, Rebecca; Caccia, Massimo; Currell, Fred; Doser, Michael; Hajdukovic, Dragan; Hartley, Oliver; Herrmann, Rochus; Jäkel, Oliver; Kantemiris, Ioannis; Kaiser, Franz-Joachim; Overgaard, Jens; Kavanagh, Joy; Knudsen, Helge; Keyes, Roy; Møller, Søren Pape; Negrini, Loretta; Ratib, Osman; Schettino, Giuseppe; Sellner, Stefan; Strasse, Tina; Tegami, Sara; Timson, David; Tölli, Heikki; Sørensen, Brita Singers; Petersen, Jørgen B.B.; Solberg, Timothy; Welsch, Carsten.

    CERN-SPSC, 2011. 28 s.

    Publikation: Forskning - peer reviewRapport

  69. 2010
  70. Udgivet

    In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome. / Myhre, Simen; Mohammed, Hayat; Tramm, Trine; Alsner, Jan; Finak, Greg; Park, Morag; Overgaard, Jens; Børresen-Dale, Anne-Lise; Frigessi, Arnoldo; Sørlie, Therese.

    I: P L o S One, Bind 5, Nr. 11, 01.12.2010, s. e14002.

    Publikation: Forskning - peer reviewTidsskriftartikel

  71. Udgivet

    Intraperitoneal administration of chitosan/DsiRNA nanoparticles targeting TNFα prevents radiation-induced fibrosis. / Nawroth, Isabel; Alsner, Jan; Behlke, Mark A; Besenbacher, Flemming; Overgaard, Jens; Howard, Kenneth A; Kjems, Jørgen.

    I: Radiotherapy & Oncology, Bind 97, Nr. 1, 01.10.2010, s. 143-8.

    Publikation: Forskning - peer reviewTidsskriftartikel

  72. Udgivet
  73. Udgivet

    Establishment of a Radiogenomics Consortium. / West, Catharine; Rosenstein, Barry S; Alsner, Jan; Azria, David; Barnett, Gillian; Begg, Adrian; Bentzen, Søren; Burnet, Neil; Chang-Claude, Jenny; Chuang, Eric; Coles, Charlotte; De Ruyck, Kim; De Ruysscher, Dirk; Dunning, Alison; Elliott, Rebecca; Fachal, Laura; Hall, Janet; Haustermans, Karin; Herskind, Carsten; Hoelscher, Tobias; Imai, Takashi; Iwakawa, Mayumi; Jones, Don; Kulich, Cecilia; Langendijk, Jan-Hans; O'Neils, Peter; Ozsahin, Mahmut; Parliament, Matthew; Polanski, Andrzej; Rosenstein, Barry; Seminara, Daniela; Symonds, Paul; Talbot, Chris; Thierens, Hubert; Vega, Ana; West, Catharine; Yarnold, John; EQUAL-ESTRO.

    I: International Journal of Radiation: Oncology - Biology - Physics, Bind 76, Nr. 5, 01.04.2010, s. 1295-6.

    Publikation: ForskningTidsskriftartikel

  74. Udgivet

    Biological Effects of Antiprotons; Are Antiprotons a Candidate for Cancer Therapy? :  Status Report for Experiment AD-4/ACE. / Holzscheiter, Michael; Alsner, Jan; Angelopoulos, Angelo; Bassler, Niels; Beyer, Gerd; Boll, Rebecca; Currell, Fred; DeMacro, John; Doser, Michael; Hajdukovic, Dragan; Hartley, Oliver; Iwamoto, Kei; Jäkel, Oliver; Kantemiris, Ioannis; Kaiser, Franz-Joachim; Kavanagh, Joy; Keyes, Roy; Knudsen, Helge; Kovacevic, Sandra; Møller, Søren Pape; Overgaard, Jens; Petersen, Jørgen B.B.; Ratib, Osman; Herrmann, Rochus; Schettino, Giuseppe; Sellner, Stefan; Tegami, Sara; Timson, David; Tölli, Heikki; Sørensen, Brita Singers; Solberg, Timothy; Vranjes, Sanja; Welsch, Carsten; Weber, Patrick; Wouters, Brad.

    CERN-SPSC, 2010. 44 s.

    Publikation: ForskningRapport

  75. Udgivet

    A technical assessment of the utility of Reverse Phase Protein Arrays for the study of the functional proteome in non-microdissected human breast cancers. / Hennessy, Bryan T; Lu, Yiling; Gonzalez-Angulo, Ana Maria; Carey, Mark S; Myhre, Simen; Ju, Zhenlin; Davies, Michael A; Liu, Wenbin; Coombes, Kevin; Meric-Bernstam, Funda; Bedrosian, Isabelle; McGahren, Mollianne; Agarwal, Roshan; Zhang, Fan; Overgaard, Jens; Alsner, Jan; Neve, Richard M; Kuo, Wen-Lin; Gray, Joe W; Børresen-Dale, Anne-Lise; Mills, Gordon B.

    I: Clinical Proteomics, Bind 6, Nr. 4, 2010, s. 129-51.

    Publikation: Forskning - peer reviewTidsskriftartikel

  76. Udgivet

    Biodistribution of 99mTc-HYNIC-lactadherin in mice - a potential tracer for visualizing apoptosis in vivo. / Falborg, Lise; Waehrens, Lasse N; Alsner, Jan; Bluhme, Henrik; Frøkiaer, Jørgen; Heegaard, Christian W; Horsman, Michael R; Rasmussen, Jan T; Rehling, Michael.

    I: Scandinavian Journal of Clinical & Laboratory Investigation, Bind 70, Nr. 3, 2010, s. 209-16.

    Publikation: Forskning - peer reviewTidsskriftartikel

  77. Udgivet

    HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer. / Lassen, P.; Eriksen, J.G.; Hamilton-Dutoit, S.; Tramm, T.; Alsner, J.; Overgaard, J.

    I: Radiotherapy & Oncology, Bind 94, Nr. 1, 2010, s. 30-5.

    Publikation: Forskning - peer reviewTidsskriftartikel

  78. Udgivet
  79. 2009
  80. Udgivet

    Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer. / Agarwal, Roshan; Gonzalez-Angulo, Ana-Maria; Myhre, Simen; Carey, Mark; Lee, Ju-Seog; Overgaard, Jens; Alsner, Jan; Stemke-Hale, Katherine; Lluch, Ana; Neve, Richard M; Kuo, Wen Lin; Sorlie, Therese; Sahin, Aysegul; Valero, Vicente; Keyomarsi, Khandan; Gray, Joe W; Børresen-Dale, Anne-Lise; Mills, Gordon B; Hennessy, Bryan T.

    I: Clinical Cancer Research, Bind 15, Nr. 11, 01.06.2009, s. 3654-3662.

    Publikation: Forskning - peer reviewTidsskriftartikel

  81. Udgivet

    Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck. / Lassen, Pernille; Eriksen, Jesper G; Hamilton-Dutoit, Stephen; Tramm, Trine; Alsner, Jan; Overgaard, Jens.

    I: Journal of Clinical Oncology, Bind 27, Nr. 12, 20.04.2009, s. 1992-8.

    Publikation: Forskning - peer reviewTidsskriftartikel

  82. Udgivet
  83. Udgivet

    Genetic variants and normal tissue toxicity after radiotherapy: a systematic review. / Andreassen, Christian Nicolaj; Alsner, Jan.

    I: Radiotherapy & Oncology, Bind 92, Nr. 3, 2009, s. 299-309.

    Publikation: Forskning - peer reviewTidsskriftartikel

  84. Udgivet

    Prognosis of Distant Metastasis in Node-Negative Early Breast Cancer. / Schmidt, M; Tramm, Trine; Böhm, D; Kyndi, M; Alsner, Jan; Kölbi, H; Stropp, U; von Törne, C; Weber, K; Henning, G; Gehrmann, M; Sampson, E.; Overgaard, Jens.

    2009. Poster session præsenteret ved AACC, Chicago, USA.

    Publikation: ForskningPoster

  85. Udgivet

    Proteins upregulated by mild and severe hypoxia in squamous cell carcinomas in vitro identified by proteomics. / Sørensen, Brita Singers; Horsman, Michael R; Vorum, Henrik; Honoré, Bent; Overgaard, Jens; Alsner, Jan.

    I: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, Bind 92, Nr. 3, 2009, s. 443-9.

    Publikation: Forskning - peer reviewTidsskriftartikel

  86. 2008
  87. Udgivet

    Genetic markers for prediction of normal tissue toxicity after radiotherapy. / Alsner, Jan; Andreassen, Christian Nicolaj; Overgaard, Jens.

    I: Seminars in Radiation Oncology, Bind 18, Nr. 2, 04.2008, s. 126-35.

    Publikation: Forskning - peer reviewTidsskriftartikel

  88. Udgivet

    Carbonic anhydrase IX and response to postmastectomy radiotherapy in high-risk breast cancer: a subgroup analysis of the DBCG82 b and c trials. / Kyndi, Marianne; Sørensen, Flemming Brandt; Knudsen, Helle; Alsner, Jan; Overgaard, Marie; Nielsen, Hanne Melgaard; Overgaard, Jens; Danish Breast Cancer Cooperative Group.

    I: Breast Cancer Research (Online Edition), Bind 10, Nr. 2, 03.2008, s. R24.

    Publikation: Forskning - peer reviewTidsskriftartikel

  89. Udgivet

    Radiation-induced gene expression in human subcutaneous fibroblasts is predictive of radiation-induced fibrosis. / Rødningen, Olaug Kristin; Børresen-Dale, Anne-Lise; Alsner, Jan; Hastie, Trevor; Overgaard, Jens.

    I: Radiotherapy & Oncology, Bind 86, Nr. 3, 03.2008, s. 314-320.

    Publikation: Forskning - peer reviewTidsskriftartikel

  90. Udgivet

    Antiproton radiotherapy. / Bassler, Niels; Alsner, Jan; Beyer, Gerd; DeMarco, John J; Doser, Michael; Hajdukovic, Dragan; Hartley, Oliver; Iwamoto, Keisuke S; Jäkel, Oliver; Knudsen, Helge V; Kovacevic, Sandra; Møller, Søren Pape; Overgaard, Jens; Petersen, Jørgen B; Solberg, Timothy D; Sørensen, Brita S; Vranjes, Sanja; Wouters, Bradly G; Holzscheiter, Michael H.

    I: Radiotherapy & Oncology, Bind 86, Nr. 1, 01.2008, s. 14-19.

    Publikation: Forskning - peer reviewTidsskriftartikel

  91. Udgivet

    A comparison among HER2, TP53, PAI-1, angiogenesis, and proliferation activity as prognostic variables in tumours from 408 patients diagnosed with early breast cancer. / Offersen, Birgitte Vrou; Alsner, Jan; Ege Olsen, Karen; Riisbro, Rikke; Brünner, Nils; Sørensen, Flemming Brandt; Sørensen, Boe Sandahl; Schlemmer, Birgitte Olrik; Overgaard, Jens.

    I: Acta Oncologica, Bind 47, Nr. 4, 2008, s. 618-32.

    Publikation: Forskning - peer reviewTidsskriftartikel

  92. Udgivet

    A comparison between p53 accumulation determined by immunohistochemistry and TP53 mutations as prognostic variables in tumours from breast cancer patients. / Alsner, Jan; Jensen, Vibeke; Kyndi, Marianne; Offersen, Birgitte Vrou; Vu, Phuong; Børresen-Dale, Anne-Lise; Overgaard, Jens.

    I: Acta Oncologica, Bind 47, Nr. 4, 2008, s. 600-7.

    Publikation: Forskning - peer reviewTidsskriftartikel

  93. Udgivet

    Antiproton therapy. / Knudsen, Helge; Holzscheiter, Michael H.; Bassler, Niels; Alsner, Jan; Beyer, Gerd; DeMarco, John J.; Doser, Michael; Hajdukovic, Dragan; Hartley, Oliver; Iwamoto, Keisuke S.; Jäkel, Oliver; Kovacevic, Sandra; Møller, Søren Pape; Overgaard, Jens; Petersen, Jørgen B.B.; Ratib, Osman; Solberg, Timothy D.; Vranjes, Sanja; Wouters, Bradly G.; the CERN ACE Collaboration.

    I: Nuclear Instruments & Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms, Bind 266, Nr. 3, 2008, s. 530-534.

    Publikation: Forskning - peer reviewTidsskriftartikel

  94. Udgivet

    Differential risk assessments from five hypoxia specific assays: The basis for biologically adapted individualized radiotherapy in advanced head and neck cancer patients. / Nordsmark, Marianne; Eriksen, Jesper Grau; Gebski, Val; Alsner, Jan; Horsman, Michael Robert; Overgaard, Jens.

    2008. Poster session præsenteret ved 10th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology, Wolfsberg, Tyskland.

    Publikation: ForskningPoster

  95. Udgivet

    HPV- associated p16 positive Head and Neck Squamous Cell Carcinomas Exhibit Improved Prognosis and Response to Radiotherapy. / Lassen, Pernille; Eriksen, Jesper Grau; Alsner, Jan; Hamilton-Dutoit, Stephen Jacques; Overgaard, Jens.

    2008. Abstract fra European Head and Neck Society, EHNS - ESTRO 2007, International Meeting on Innovative Approaches in Head and Neck Oncology, Barcelona, Spanien.

    Publikation: ForskningKonferenceabstrakt til konference

  96. Udgivet

    Human papillomavirus in head and neck cancer: a potential prognostic factor and predictor of response to radiotherapy. / Lassen, Pernille; Eriksen, Jesper Grau; Alsner, Jan; Hamilton-Dutoit, Stephen Jacques; Overgaard, Jens.

    2008. Abstract fra PhD dag, Aarhus Universitet, Århus, Danmark.

    Publikation: ForskningKonferenceabstrakt til konference

  97. Udgivet

    Hypoxia induced expression of endogenous markers in vitro is highly influenced by pH. / Sørensen, Brita Singers; Horsman, Michael Robert; Overgaard, Jens; Alsner, Jan.

    2008. Poster session præsenteret ved 10th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology, Wolfsberg, Schweiz.

    Publikation: ForskningPoster

  98. Udgivet

    Impact of BCL2 and p53 on postmastectomy radiotherapy response in high-risk breast cancer. A subgroup analysis of DBCG82 b&c. / Kyndi, Marianne; Sørensen, Flemming Brandt; Knudsen, Helle; Alsner, Jan; Overgaard, Marie; Nielsen, Hanne Melgaard; Overgaard, Jens.

    I: Acta Oncologica, Bind 47, Nr. 4, 2008, s. 608-617.

    Publikation: Forskning - peer reviewTidsskriftartikel

  99. Udgivet

    The impact of hypoxia on the activity of lactate dehydrogenase in two different pre-clinical tumour models. / Lukacova, Slavka; Sørensen, Brita; Alsner, Jan; Overgaard, Jens; Horsman, Michael.

    I: Acta Oncologica, Bind 47, Nr. 5, 2008, s. 941-47.

    Publikation: Forskning - peer reviewTidsskriftartikel

  100. Udgivet

    Transformation of human mesenchymal stem cells in radiation carcinogenesis: long-term effect of ionizing radiation. / Christensen, Rikke; Alsner, Jan; Sørensen, Flemming Brandt; Dagnaes-Hansen, Frederik; Kolvraa, Steen; Serakinci, Nedime.

    I: Regenerative Medicine, Bind 3, Nr. 6, 2008, s. 849-61.

    Publikation: Forskning - peer reviewTidsskriftartikel

  101. 2007
  102. Udgivet

    Differential gene expression before and after ionizing radiation of subcutaneous fibroblasts identifies breast cancer patients resistant to radiation-induced fibrosis. / Alsner, Jan; Rødningen, Olaug K.; Overgaard, Jens.

    I: Radiotherapy & Oncology, Bind 83, Nr. 3, 06.2007, s. 261-266.

    Publikation: Forskning - peer reviewTidsskriftartikel

  103. Udgivet
  104. Udgivet

    Hypoxia induced expression of endogenous markers in vitro is highly influenced by pH. / Sørensen, Brita Singers; Alsner, Jan; Overgaard, Jens; Horsman, Michael Robert.

    I: Radiotherapy & Oncology, Bind 83, Nr. 3, 06.2007, s. 362-366.

    Publikation: Forskning - peer reviewTidsskriftartikel

  105. Udgivet

    Reproductive death of cancer cells induced by femtosecond laser pulses. / Thøgersen, Jan; Knudsen, Cindy S; Maetzke, Alice; Jensen, Svend Knak; Keiding, Søren R; Alsner, Jan; Overgaard, Jens.

    I: International Journal of Radiation Biology, Bind 83, Nr. 5, 05.2007, s. 289-99.

    Publikation: Forskning - peer reviewTidsskriftartikel

  106. Udgivet

    Biodistribution and tracer kinetics in small and large animals of 99mTc-HYNIC-lactadherin compared to 99mTc-HYNIC-annexin V. / Falborg, Lise; Wæhrens, Lasse Neumann; Alsner, Jan; Dissing, Thomas Heide; Eilersen, J; Frøkiær, Jørgen; Heegaard, Christian Wurtz; Horsman, Michael Robert; Rasmussen, Jan Trige; Nielsen, Søren Steen; Rehling, Michael.

    I: European Journal of Nuclear Medicine and Molecular Imaging, 2007, s. S395.

    Publikation: ForskningKonferenceabstrakt i tidsskrift

  107. Udgivet

    Ectopically hTERT expressing adult human mesenchymal stem cells are less radiosensitive than their telomerase negative counterpart. / Serakinci, Nedime; Christensen, Rikke; Graakjaer, Jesper; Cairney, Claire J; Keith, W Nicol; Alsner, Jan; Saretzki, Gabriele; Kolvraa, Steen; Christensen, Rikke.

    I: Experimental Cell Research, Bind 313, Nr. 5, 2007, s. 1056-67.

    Publikation: Forskning - peer reviewTidsskriftartikel

  108. 2006
  109. Udgivet

    Focal S100A4 protein expression is an independent predictor of development of metastatic disease in cystectomized bladder cancer patients. / Agerbæk, Mads; Alsner, Jan; Marcussen, Niels; Lundbeck, Finn; Maase, Hans von der.

    I: European Urology, Bind 50, Nr. 4, 10.2006, s. 777-785.

    Publikation: Forskning - peer reviewTidsskriftartikel

  110. Udgivet

    Risk of radiation-induced subcutaneous fibrosis in relation to single nucleotide polymorphisms in TGFB1, SOD2, XRCC1, XRCC3, APEX and ATM - a study based on DNA from formalin fixed paraffin embedded tissue samples. / Andreassen, Christian Nicolaj; Alsner, Jan; Overgaard, Marie; Sørensen, Flemming Brandt; Overgaard, Jens.

    I: International Journal of Radiation Biology, Bind 82, Nr. 8, 08.2006, s. 577-586.

    Publikation: Forskning - peer reviewTidsskriftartikel

  111. Udgivet

    Strain and tumour specific variations in the effect of hypoxia on osteopontin levels in experimental models. / Lukácová, Slávka; Overgaard, Jens; Alsner, Jan; Horsman, Michael Robert.

    I: Radiotherapy & Oncology, Bind 80, Nr. 2, 08.2006, s. 165-171.

    Publikation: Forskning - peer reviewTidsskriftartikel

  112. Udgivet

    ATM sequence variants and risk of radiation-induced subcutaneous fibrosis after postmastectomy radiotherapy. / Andreassen, Christian Nicolaj; Overgaard, Jens; Alsner, Jan; Overgaard, Marie; Herskind, Carsten; Cesaretti, Jamie A; Atencio, David P; Green, Sheryl; Formenti, Silvia C; Stock, Richard G; Rosenstein, Barry S.

    I: International Journal of Radiation: Oncology - Biology - Physics, Bind 64, Nr. 3, 01.03.2006, s. 776-783.

    Publikation: Forskning - peer reviewTidsskriftartikel

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